1.Primary Leiomyosarcoma in Bladder
Tae Wook KANG ; Min Seob EOM ; Hyun Chul CHUNG
Korean Journal of Urological Oncology 2019;17(1):66-69
Leiomyosarcoma of the bladder is a very rare tumor and it has been reported in less than 200 cases in the literature which represent 0.1% of all nonurothelial bladder tumors. We experienced a case of sarcoma of bladder that protruding into the urinary bladder in 51-year-old woman. She underwent mass excision with enucleation for the bladder function preservation. Pathologically, the mass consisted of high grade leiomyosarcoma. In immunohistochemical study, tumor showed positive reactions for smooth muscle actin and desmin. After mass excision, follow-up radiation treatment is ongoing. Herein, we present the case of a high-grade leiomyosarcoma with literature review.
Actins
;
Desmin
;
Female
;
Follow-Up Studies
;
Humans
;
Leiomyosarcoma
;
Middle Aged
;
Muscle, Smooth
;
Sarcoma
;
Urinary Bladder Neoplasms
;
Urinary Bladder
2.Tubular Apocrine Adenoma with Syringocystadenoma Papilliferum of the External Auditory Canal.
Min Suk KANG ; Ju Shin LIM ; Sang Yoo PARK ; Min Seob EOM
Korean Journal of Otolaryngology - Head and Neck Surgery 2012;55(8):518-520
Tumors that develop from external auditory canal (EAC) are very rare. Adenoma that originates from apocrine is also a rare entity found in the EAC. Nevus sebaceous, syringocystadenoma papilliferum (SCAP), tubular apocrine adenoma (TAA), and fibroadenoma are known to originate from apocrine. Among them, SCAP is believed to be a benign tumor that is manifested as papule and plague on the scalp and the face. However, TAA is a rare intradermal eccrine tumor and it mostly manifests as an isolated single nodule within the scalp area. Generally, these tumors are considered as two separate entities. Many articles have reported on the prevalence of TAA or SCAP with nevus sebaceous on the body, extremities, and scalp; but only 2 articles were reported on tumors that developed from EAC. In this article, we report on a patient who presented a mass in EAC, with both SCAP and TAA pathohistologic finding without nevus sebaceous.
Adenoma
;
Aminocaproic Acids
;
Apocrine Glands
;
Ear Canal
;
Extremities
;
Fibroadenoma
;
Humans
;
Nevus
;
Plague
;
Prevalence
;
Scalp
3.Placental Transmogrification of the Lung.
Jin Woo KIM ; Il Hwan PARK ; Woocheol KWON ; Min Seob EOM ; Young Ju KIM ; Joong Hwan OH
Korean Journal of Radiology 2013;14(6):977-980
Placental transmogrification is a very rare lung disease, where the alveoli resemble the chorionic villi of placenta, and this change is a characteristic finding. A 31-year-old female patient presented with cough and dyspnea that had begun 2 weeks prior to admission. Along with giant bulla found in the left upper lung field, subsegmental consolidation was also identified in the lingular segment on plain chest radiograph and CT scan. Wedge resection was performed to remove the bulla. Pathologic examination of the resected bulla revealed destruction of the normal structures and characteristic villous and papillary changes. These changes led to a diagnosis of placental transmogrification. We made an encounter of an unusual placental transmogrification which had different image findings from other reported transmogrification cases. Thus, we report an atypical placental transmogrification case where both consolidation and giant bulla coexist.
Adult
;
Chorionic Villi/*pathology
;
Diagnosis, Differential
;
Female
;
Humans
;
Lung/*pathology/radiography/surgery
;
Lung Diseases/pathology/*radiography/surgery
;
Pneumonectomy
;
Tomography, X-Ray Computed/*methods
4.Forensic Consideration of Postpartum Acute Myocardial Infarction Associated with Ergot Derivatives Administration in Old Aged Woman: A Case Report.
Min Seob EOM ; Young Joo KIM ; Youn Shin KIM ; Han Young LEE ; Ho LEE
Korean Journal of Legal Medicine 2005;29(1):52-55
Cases of acute myocardial infarction (AMI) that occurs during pregnancy or postpartum are rarely reported. Ergot derivatives were known to induce spasmodic contraction of coronary arteries. Administration of ergot derivatives can cause AMI even in normal healthy people. Several cases are also reported that ergot derivatives may trigger severe AMI in postpartum period. Here, we report a case of a forty-year-old pregnant woman who was succeeded to be pregnant by artificial fertilization died after treatment with ergot derivatives. Examinations of autopsy have revealed AMI with severe coronary atherosclerosis. This case is the first report which shows aggravation of preexistent severe coronary atherosclerosis after postpartum infusion of ergot derivatives.
Autopsy
;
Coronary Artery Disease
;
Coronary Vessels
;
Ergot Alkaloids
;
Female
;
Fertilization
;
Humans
;
Myocardial Infarction*
;
Postpartum Period*
;
Pregnancy
;
Pregnant Women
5.Local Recurrence of Spermatic Cord Leiomyosarcoma.
Hyun Chul CHUNG ; Hyo Serk LEE ; Tae Im KIM ; Min Seob EOM ; Jae Mann SONG
Korean Journal of Urology 2009;50(1):92-95
A leiomyosarcoma of the spermatic cord is an extremely rare tumor. A 73-year-old man complained of a soft, palpable mass in the right inguinal canal. Transinguinal radical orchiectomy was performed and histologic examination revealed leiomyosarcoma originating from the spermatic cord. Distant metastases were not observed by further examinations. At 7 months postoperatively, a local recurrence developed. Reoperative wide resection was performed and a negative margin was obtained. At 9 months reoperatively, there has been no recurrence or metastasis.
Aged
;
Humans
;
Inguinal Canal
;
Leiomyosarcoma
;
Neoplasm Metastasis
;
Neoplasm Recurrence, Local
;
Orchiectomy
;
Recurrence
;
Spermatic Cord
6.A Case of Intramural Pregnancy.
Jung Sik HA ; In Bai CHUNG ; Joo Hyung CHO ; Hyang A LEE ; Min Seob EOM ; Kwang Hwa PARK
Korean Journal of Obstetrics and Gynecology 2003;46(11):2323-2327
Intramural pregnancy is one of the rarest forms of ectopic pregnancy. The pathologic diagnosis of the intramural ectopic pregnancy requires that the myometrium surrounds the products of conception separated from the endometrial cavity or fallopian tubes. Because the early diagnosis is very difficult, most cases are found after the onset of complications such as a uterine rupture or hemoperitoneum. The previous histories of curettage, cesarean section, myomectomy, salpingectomy and manual removal of the placenta are known as possible etiology of the intramural pregnancy. We have recently experienced a case of intramural pregnancy after 10 times of curettages and are reporting with a brief review of the literatures.
Animals
;
Cesarean Section
;
Curettage
;
Diagnosis
;
Early Diagnosis
;
Fallopian Tubes
;
Female
;
Fertilization
;
Hemoperitoneum
;
Mice
;
Myometrium
;
Placenta
;
Pregnancy*
;
Pregnancy, Ectopic
;
Salpingectomy
;
Uterine Rupture
7.Eccrine Poroma of the Auricle: A Case Report.
Tae Hoon KONG ; Tae Hyoung HA ; Min Seob EOM ; Sang Yoo PARK
Korean Journal of Audiology 2014;18(3):151-152
Eccrine poroma is described as a benign neoplasm originating from the intraepidermal eccrine duct of sweat glands. This tumor is known to arise in bare skin areas, but more rarely appeared in head and neck region. A 54-year-old female presented with a mass on the retroauricular aspect of the left auricle. There was a soft, protruding, and purple-colored, solitary mass of about 1.0x1.0 cm in size. After authors performed an excisional biopsy, eccrine poroma was confirmed histopathologically. Thus, we report a rare case of eccrine poroma of the ear with the review of literature.
Biopsy
;
Ear
;
Ear Auricle
;
Female
;
Head
;
Humans
;
Middle Aged
;
Neck
;
Poroma*
;
Skin
;
Sweat Glands
8.Membranoproliferative Glomerulonephritis Associated with Papillary Thyroid Carcinoma.
Seung Tae HAN ; Seung Ok CHOI ; Shin Han SONG ; Jae Seok KIM ; Min Seob EOM ; Jong In LEE ; Min Keun KIM ; Byoung Geun HAN ; Jae Won YANG
Korean Journal of Nephrology 2011;30(2):183-186
Malignant tumors have been shown to be a major secondary cause of nephrotic syndrome. They have been associated with different glomerulopathy depending on their type. Membranoproliferative glomerulonephritis (MPGN) rarely develops in solid tumors, although cases have been reported in renal cell cancer, melanoma, lung cancer, and tumors in the urogenital system. However, to our knowledge, there have been no case reported of MPGN associated with thyroid cancer. In the present case, we observed MPGN associated with thyroid cancer in a 44-year-old woman with nephrotic syndrome and renal insufficiency. Her thyroid ultrasound revealed a tumor measuring 1.01x1.14x1.48 cm with an indistinct border that was partially calcified. The tumor was confirmed to be papillary carcinoma by percutaneous needle aspiration biopsy. Renal biopsy showed chronic tubulointerstitial nephritis and MPGN. On day 45 of admission, total thyroidectomy and neck lymphadenectomy were performed. After total thyroidectomy, serum total protein, albumin, C3, and C4 normalized. In conclusion, this case represents the first report of simultaneous development of MPGN and thyroid cancer.
Adult
;
Biopsy
;
Biopsy, Needle
;
Carcinoma
;
Carcinoma, Papillary
;
Carcinoma, Renal Cell
;
Female
;
Glomerulonephritis, Membranoproliferative
;
Humans
;
Lung Neoplasms
;
Lymph Node Excision
;
Melanoma
;
Neck
;
Needles
;
Nephritis, Interstitial
;
Nephrotic Syndrome
;
Renal Insufficiency
;
Thyroid Gland
;
Thyroid Neoplasms
;
Thyroidectomy
;
Urogenital System
9.A High Thymidylate Synthase Expression is Related to Better Outcome for Advanced Gastric Cancer Patients Treated with 5-FU Chemotherapy after Curative Resection.
Mee Yon CHO ; Sang Yeop YI ; Min seob EOM ; Shu Peng ZHANG ; Hwan Sik KIM ; Jong In LEE ; Dae Sung KIM
Korean Journal of Pathology 2006;40(2):128-136
BACKGROUND: The expressions of thymidylate synthase (TS), E2F-1, pRb, and p53 are correlated with DNA synthesis. The significance of their expressions is still controversial for predicting the outcome of 5-fluorouracil (5-FU) therapy in the patients with advanced gastric carcinoma. Furthermore, their prognostic value in the metastatic lesions of gastric carcinoma has not yet been confirmed. METHODS: To ascertain their prognostic value, we immunohistochemically analyzed the expressions of TS, E2F-1, pRb, and p53 in the primary tumors and the related metastatic lymph nodes, and we then compared the survival between the high and low expression group of each protein. Ninety four patients with advanced gastric carcinoma who were treated by complete resection and adjuvant 5-FU chemotherapy were analyzed. RESULTS: The TS expression in primary tumors was significantly correlated with that of E2F-1. The expression of these genes showed no significant difference between the primary tumors and the metastatic lymph nodes except for E2F-1, which was significantly higher in the lymph node metastasis than in the primary tumors. After complete resection and 5-FU-based adjuvant chemotherapy, patients with a high TS expression in the primary tumors showed a longer survival than those patients having primary tumors with a low TS expression (p=0.0392). CONCLUSION: A high TS expression in the primary tumors may be related to a better outcome for advanced gastric cancer patients who were treated with 5-FU chemotherapy after curative resection.
Chemotherapy, Adjuvant
;
DNA
;
Drug Therapy*
;
Fluorouracil*
;
Humans
;
Lymph Nodes
;
Neoplasm Metastasis
;
Stomach Neoplasms*
;
Thymidylate Synthase*
10.A Case Related to Identifying the Missing Person.
Eung Soo KIM ; Moon Hee PARK ; Kyung Ryong LEE ; Byung Ha CHOI ; Young Joo KIM ; Dae Yeol KIM ; Sung Jin CHO ; Min Seob EOM ; Young Shik CHOI
Korean Journal of Legal Medicine 2007;31(1):59-61
The application of DNA typing method after amplification by the polymerase chain reaction (PCR) of DNA derived from bone from two missing persons. In this case, short tandem repeats (STR) are used. The AmpFlSTR Identifiler loci (amelogenin and 15 STRs) are analysed by multiplex-PCR and automated fluorescent detection using Perkin Elmer Prism 310 DNA sequencer.
DNA
;
DNA Fingerprinting
;
Humans
;
Microsatellite Repeats
;
Polymerase Chain Reaction