Objective:To investigate the situation of narcotic drug use in the out-patient department of our hospital to provide reference for the rational use of drugs.Method:By collecting all the prescriptions of the out-patient department of our hospital in 2007,the designations,dosages,dosage form,usage,synptoms and section offices of the narcotic drug were statistically analyzed.Result:Top 3 of the prescriptions amounts in the out-patient department were morphine sulfate sustained-Relrase tablets,pethidine hydrochloride injection and oxycodone hydrochloride sustained-release tablets. Top 3 of the prescriptions amounts in DUI were fentanyl citrate injecton,bucinnazine hydrochlooride injection and morphine hydrochloride injection.Conclusion:The narcotic drug used in the out-patient clinic of our hospital is rational on the whole,and the doctors and pharmacists should pay much attention to the use and management of narcotic drug.

Objective To compare disinfection efficacy of three different air disinfection methods on the air in blood collection room.Methods Air disinfection in blood collection room was conducted by ultraviolet (UV)light, ozone disinfector (OD)and air purification disinfector respectively ,natural sedimentation method was used to take air specimens before ,after disinfection ,and during working condition of staff ,air disinfection efficacy was detec-ted.Results All three methods could decrease air bacterial count after disinfection ,the total number of bacteria in indoor air after disinfection met the class Ⅲ environmental requirement.Under working condition of staff ,the num-ber of bacteria of OD and UV light group increased rapidly,at 4 hours was (7.53±1.28)CFU/5 min·Φ90petri dish and (8.16±1.57)CFU/5 min·Φ90petri dish respectively;air purification disinfector disinfected for 4 hours under the condition of movement of personnel in blood collection environment,bacteria count still remained <4.0 CFU/5 min·Φ90petri dish.Conclusion Disinfecting continuously by air purification disinfector can ensure the effectiveness of air cleanliness in blood collection room.

Adenocarcinoma ; metabolism ; pathology ; Aged ; Carcinoid Tumor ; metabolism ; pathology ; Chromogranin A ; metabolism ; Humans ; Immunohistochemistry ; Male ; Neoplasms, Multiple Primary ; metabolism ; pathology ; Phosphopyruvate Hydratase ; metabolism ; Rectal Neoplasms ; metabolism ; pathology ; S100 Proteins ; metabolism

Medical thermostat water bath cauldron is widely used in clinic,but its temperature control is not accurate.This paper presents a digitalized revolution on medical thermostat water bath cauldron.

AIM To study an analytical method of fingerprint for Adina pilulifera (Lam.)Franch. ex Drake in order to ensure the quality of this medicinal material. METHODS RP-HPLC was used to detect 6 batches of this medicinal material collected in main production areas. The experiment was carried out by using Agilent ZORBAX Extend C_ 18 column (4.6 mm?250 mm), methanol:water (23∶ 77) and 258 nm. RESULTS This RP-HPLC method was accurate, stable and reproducible, and the main peaks in the spectrum were all separated perfectly. CONCLUSION The developed method is simple, accurate and operable, and can be used to control the quality of Adina pilulifera (Lam.)Franch.ex Drake efficiently and feasibly.

Mesenchymal stem cell (MSC) resides in a relatively hypoxia niche (volume fraction 1％～7％)compared to normoxia (20％).MSC cultured in hypoxia condition shows different biological features from those in normoxia condition.Hypoxia inducible factor-1 α (HIF-1 α),as one of main transcription factors in hypoxia,participates in the regulation of cell proliferation,differentiation,apoptosis,glycolysis and angiogenesis.Recent researches show that HIF-lα also plays an important role in regulating the survival,differentiation and migration of MSC.It turns out that hypoxia can improve survival and migration of MSC,enhance chondrogenesis but inhibit adipogenesis through HIF-lα and its downstream genes.However,whether hypoxia promotes or impedes osteogenesis remains controversial.Such differences can be caused by variances of tissue origination,oxygen concentration and culture condition.The comparison of different researches should be based on the same experiment condition.This review focuses on the influence of hypoxia on proliferation,apoptosis,differentiation and migration of MSC.

The electroencephalogram (EEG) has proved to be a valuable tool in the study of comprehensive conditions whose effects are manifest in the electrical brain activity, and epilepsy is one of such conditions. In the study, multiscale permutation entropy (MPE) was proposed to describe dynamical characteristics of EEG recordings from epilepsy and healthy subjects, then all the characteristic parameters were forwarded into a support vector machine (SVM) for classification. The classification accuracies of the MPE with SVM were evaluated by a series of experiments. It is indicated that the dynamical characteristics of EEG data with MPE could identify the differences among healthy, interictal and ictal states, and there was a reduction of MPE of EEG from the healthy and interictal state to the ictal state. Experimental results demonstrated that average classification accuracy was 100% by using the MPE as a feature to characterize the healthy and seizure, while 99. 58% accuracy was obtained to distinguish the seizure-free and seizure EEG. In addition, the single-scale permutation entropy (PE) at scales 1-5 was put into the SVM for classification at the same time for comparative analysis. The simulation results demonstrated that the proposed method could be a very powerful algorithm for seizure prediction and could have much better performance than the methods hased on single sale PF
Algorithms ; Electroencephalography ; Entropy ; Epilepsy ; Healthy Volunteers ; Humans ; Seizures ; diagnosis ; Support Vector Machine

The β-cyclodextrin cross-linked polymer(β-CDCP) was used as adsorbent to pre-concentrate/separate the trace p-nitrophenol and then the determination was carried by UV-Vis spectrophotometry. Under alkaline condition,the adsorption/elution behavior of p-nitrophenol was studied. In 0. 02 mol/L NaOH solution and at room temperature for 30 min,the resin could separate and pre-concentrate the p-nitrophenol effectively. Methanol solution(1:1,V/V) was used as eluent and the β-CDCP could be used repeatedly. The linear range and detection limit was 0.5 -90.0 mg/L and 3. 10 μg/L,respectively. The proposed method has been used to determine the p-nitrophenol in synthesized sample with satisfactory results.

Acute pancreatitis is acute inflammation due to autodigestion of pancreatic tissue by trypsogen activation, can induce systemic inflammatory reaction,and deteriorate to be nonfunction and fatality. Nuclear factor kappa B seizes the coral position in the development of acute pancreatitis, regulates gene expression of inflammatory factors and immune protein. This article reviews the therapy of pancreatitis on account of NF-κB.

Objective To explore the effect of palliative care led by oncology professional nurses in the elderly patients with late tumor. Methods Ninety patients who were diagnosed with late tumor were randomly divided into control group and intervention group. Routine nursing care was conducted in the control group and in the intervention group, palliative care lead by professional nurses was conducted besides the routine nursing care for 8 weeks. The two groups were compared in view of life, symptom distress, and self-efficacy intervention effect. Result The quality of life and self-efficacy were significantly higher than those of the control group (P<0.05) and the symptom distress was significantly lower than that of the control group eight weeks after the intervention (P<0.05). Conclusion The multi-disciplinary intervention led by the oncology professional nurses can improve the quality of life and self-efficacy of the patient and improve the symptoms of the patient.