10 adult female rats were used to study blast injuries of the air-way and lung. The conclusions are as follows. 1. There was significant difference in arterial blood gas analysis between the normal control and injury group. 2. The une-venness in the lung damage, bleeding, tear of the alveolar septa induced by the air shock wave was predominant, by scanning electron microscopy (SEM) as well as by the light microscopy (LM) . The bleeding may be due to the capillary rupture of alveolar septa. The' rope-like' structures seen might represent the fibre component in the septa which had more resistance to the local force and remained after the other components were wiped away by explosion. 3. Striping and fissure of the epithelium of trachea and bronchi of the injured group were detected. 4. The pathological changes observed with SEM were compared to those with LM.

The morphological changes of the rat lung with blast injury are quantitified with a stereological method. After blast the pulmonary capillary volume and internal surface area decreased significantly, arithrnatic and harmonic mean thickness of the air-blood barrier, the volumes of P'MN and platelet in capillury increased remarkably. The morphometric lung diffusion capacity of oxygen (DLO2) is reduced markedly mainly due to the decrease of diffusion capacity of air-blood barrier and erythrocyte. The change of DLO2 is closely correlated with the arterial blood oxygen pressure, indicated that the damage of pulmonary capillary is one of the main causes of alveolar bleeding and the early respiratory insufficiency. A mathematic relation can be established between the intensity of the blast wave and the corresponding morphological changes of the injured lungs.

Semaphorins is the one of guidance molecule families.It is proved to have wide physiological function in the development of neutron and play important role in the pathogenesis of retinal degenerative diseases,gangliocyte apoptosis-related diseases and neovascularization.Previous studies showed that Semaphorins distribute in the cornea,lens and retina.Semaphorins play important role in the development of retina,visual system,cornea nerve and reduce the death of retinal ganglion cells(RGCs)caused by glaucoma,retinal detachment and hypoxic ischemic optic neuropathy.Semaphorin family-related gene mutation may be associated with retinal degenerative diseases.Some of the members could also inhibit angiogenesis.Since semaphorins and its receptors participate in the development of the vasculature and nervous systems,they are implied to be the potential new target of ophthalmopathic treatment.The current ptogress in structure and functions of the semaphorin family along with their relationship with ophthalmopathy were summarized in this study.

Object To provide an economical and practical technique for planting of Radix Gentianae in large scale Methods Indoor artificial pregermination, insemination in carboxymethyl cellulose suspension, irrigation with micro sprayer and no shelter growing technique of seedling Results The seedling cost is 60% lower than that of conventional technique In each square meter 3 000 seedlings were grown Conclusion This technique can be widely applied.

Object To investigate the reason of the low germination and sprout rates by studying on inhibitory activities of the crude extracts of the seed of the dried root of Saposhnikovia divaricata (Turcz.) Schischk (DRSD) on Brassica, wheat and the seed of DRSD. Methods The ether extract and residue of the crude extract were prepared and treated by paper chromatography. The inhibitory activities of different fractions with different Rf value were determined. Effect of steeping the seed in warm water at 41 ℃ and 45 ℃ for different periods of time was also studied, respectively. Results There are intrinsic inhibitor in the seed of DRSD with strong activity. The portion of its ether extract with Rf 0.6 showed the strongest inhibitory activity for the germination of Brassica seed. The crude extract of the seed of DRSD also has the stronger inhibitory activity to the germination and growth of tender root of S. divaricata and has the same effect on aerial part of wheat sprouts. Steeping with warm water and solvent can remove most of the intrinsic inhibitor. Conclusion Intrinsic inhibitor in the seed of DRSD is the main factor that results in the low germination and sprouting slowly after seeding.

Objective To compare the clinical effect between SMA concentrator and tension band internal fixation for the treatment of patellar comminuted facture. Methods Retrospective analysis of 132 cases of patellar fracture surgery patients,72 cases of them with internal fixation by SMA concentrator,the other 60cases with tension band internal fixation. Results All patients were followed up for 6 to 16 months. The recovery rate of sma concertrator was 95.8% and that of tension hard internal fixation was 88. 3%. Conclusion Using SMA concentrator to treat patellar comminuted fracture was a better treatment.

China ; Feeding Methods ; Female ; Humans ; Infant, Newborn ; Infant, Premature ; growth & development ; Infection ; complications ; therapy ; Obstetric Labor, Premature ; complications ; mortality ; Pregnancy ; Respiration, Artificial ; Respiratory Therapy ; Survival Rate

Cardiomyopathies ; chemically induced ; Chlorine Compounds ; poisoning ; Female ; Humans ; Middle Aged ; Oxides ; poisoning

Objective To compare the strength of oxidative stress from different concentrations of oxygen administered by the accumulation of hydroxyl radicals during early reperfusion after global brain ischemia.Methods Sixteen adult male Mongolian gerbils with microdialysis probes implanted in the hippocampal CA1 were divided randomly (random number)into two groups (n =8 in each).All gerbils of both groups were subjected to 10 min bilateral carotid artery occlusion (BCAO).Then the following intervention:(a) immediate 30% O2 (near normoxia,NO group ) and (b ) immediate 100% O2 (hyperoxia,HO group).The accumulation of hydroxyl radicals (·OH)in hippocampus during reperfusion was estimated by measuring 2,3-dihydroxybenzoic acid (DHBA ) and 2,5-DHBA in microdialysis perfusate.Results Immediately after the onset of reperfusion,two groups showed markedly elevated DHBA,which returned to baseline gradually.Compared with the NO group,the HO group showed significantly higher peak DHBA and slower recovery.Conclusions Hydroxyl radical accumulation was more sensitive to inhalation of high concentration O2 during early reperfusion of global cerebral ischemia.

Objective To study the role of ARHI protein and COX-2 protein and to explore their correlation in pathogenesis of adenocarcinoma of the uterine cervix.Methods The expression of ARHI and COX-2 protein were detected both in 40 cases of adenocarcinoma of the uterine cervix and in 30 cases of normal cervix by immunohistochemistry.Results The positive rate of the expression of ARHI protein in adenocarcinoma of the uterine cervix was 50.0％ (20/40),which lower than that in normol cervix controls 90.0％ (27/30),the difference was significant ( x2 =12.43,P ＜ 0.05 ) ; The positive rate of the expression of COX-2 protein in adenocarcinoma of the uterine cervix was 82.5 ％ (33/40),which higher than that in normol cervix controls 0 (0/30),the difference was significant (x2 =46.16,P ＜ 0.05 ) ;The positive expression rate of ARHI was negatively correlated with the clinical stage of cervical adenocarcinoma ( x2 =3.96,P ＜ 0.05 ) disease and pathological grade (x2 =7.04,P ＜ 0.05 ).COX-2 protein was positively correlated with pathological grade (x2 =7.04,P ＜0.05 ),but had no correlation with the clinical stage of cervical adenocarcinomacervical adenocarcinoma stage of diseas(P ＞ 0.05) ;The expression of ARHI protein and COX-2 protein wasn't correlated with lymph nodeatic meatastasis(P ＞ 0.05);The expression of ARHI protein had correlation with the expression of COX-2 protein (r =0.31,P ＜ 0.05 ).Conclusion Inactivation of ARHI gene and the abnormal expression of COX-2 protein are involved in the origin of cervical adenocarcinoma,their synergistic reaction may play an important role in tumor origin of cervical adenocarcinoma.