No Abstract Available.
Adenoma*

No abstract available.
Bronchoalveolar Lavage Fluid* ; Bronchoalveolar Lavage* ; Silicosis*

PURPOSE: The purpose of this study was to evaluate the clinical features and the courses and effects of long-term treatment, and to analyze the association between clinical features and duration of therapy in chronic functional constipation in children. METHODS: This study enrolled 57 children with chronic functional constipation who were treated in the Eulji Hospital for more than five months between May, 2000 and February, 2004. We analyzed the clinical features and the courses and results of the phase of disimpaction, maintenance, weaning retrospectively. RESULTS: Mean age at diagnosis was 3.3+/-2.3 years and the male to female ratio was 24:33. The mean duration of symptoms was 12.5+/-13.9 months in 49 patients. Mean defecation frequency per week was 5.7+/-4.0 and hard stools were seen in 59.7% of patients. The clinical presentations were as follows : abdominal pain(45.6%), rectal blood loss(28.1%), vomiting(19.3%). Fifty-four patients had successful disimpaction with lactulose+bisacodyl/glycerine enema or only lactulose, except for three patients with polyethylene glycol(PEG) solution. After a maintenance phase with lactulose or lactulose+mineral oil, a significant increase in defecation frequency per week was observed(5.7+/-4.0 to 6.3+/-1.8(P<0.05)), discomfort in defecation was not observed in all patients and hard stools were not observed except in four patients. The mean duration of the maintenance phase was 5.5+/-4.3 months and mean duration of total therapy was 10.8+/-3.8 months in 42 patients who finished the weaning phase. Duration of the maintenance phase and of total therapy had no statistical correlation with age, duration of symptoms and frequency of stools, and had no association with clinical presentations. CONCLUSION: Long-term treatment is necessary for effective treatment of chronic functional constipation in children. Further long-term follow up would have to be perfomed to evaluate successful treatment.
Child* ; Constipation* ; Defecation ; Diagnosis ; Enema ; Female ; Follow-Up Studies ; Humans ; Lactulose ; Male ; Mineral Oil ; Polyethylene ; Retrospective Studies ; Weaning

Background and Objectives: Recurrence rates after radiofrequency catheter ablation (RFCA) in atrial fibrillation (AF) patients are not low especially in non-paroxysmal AF. The diameter of left atrium (LA) has been widely used to predict the recurrence after RFCA for decades. However, LA diameter represents structural remodeling of LA and does not reflect electrical remodeling. We aimed to determine the predictive value of electrical remodeling of LA which is represented by the amount of low voltage zone (LVZ). Methods: We performed a retrospective cohort analysis of AF patients who underwent de novo RFCA in a single-center. Results: A total of 3,120 AF patients with de novo RFCA were analyzed. Among these patients, 537 patients underwent an electroanatomic mapping with bipolar voltage measurement of LA.The diameter of LA and flow velocity of LA appendage (LAA) differed significantly according to quartile group of LVZ area and percentage: patients with high LVZ had large LA diameter and low LAA flow velocity (p<0.001). Freedom from late recurrence (LR) was significantly lower in patients with high LVZ area and percentage (p<0.001). The diameter and surface area of LA had area under curve (AUC) of 0.592 and 0.593, respectively (p=0.002 for both). The predictive value of LVZ area (AUC, 0.676) and percentage (AUC, 0.671) were both superior compared with LA diameter (p=0.011 and 0.027 for each comparison). Conclusions In conclusion, LVZ can predict freedom from LR after RFCA in AF patients. Predictive value was higher in parameters reflecting electrical rather than structural remodeling of LA.

PURPOSE: Heart to liver ratio on T1-201 per rectal scintigraphy (shunt index) is known to be useful in the assessment of portal systemic shunt. We assessed T1-201 uptake pattern and early liver/heart uptake rate of T1-201 and correlated with shunt index in patients with chronic active hepatitis (CAH) and liver cirrhosis (LC). MATERIALS AND METHODS: Fifty eight patients with biopsy-proven chronic liver disease (35 with CAH, 23 with LC) underwent T1-201 per rectum scintigraphy after instillation of 18.5 MBq of T1-201 into the upper rectum. We evaluated hepatic uptake (type 1: homogeneous, 2: inhomogeneous segmental, 3: inhomogeneous nonsegmental) and extrahepatic uptake of spleen, heart and kidney (grade 0: no uptake, 1: less than liver, 2: equal to liver, 3: greater than liver). We measured the early liver/heart uptake rate (the slope of the liver to heart uptake ratio for 10 min) and shunt index (heart to liver uptake ratio). T1-201 uptake pattern and early liver/heart uptake rate of T1-201 was correlated with the pathologic diagnosis and shunt index. RESULTS: Hepatic uptake patterns of type 1 and 2 were dominant in CAH (CAH: 27/35, LC: 8/23), and type 3 in LC (CAH: 8/35, LC: 15/23) (p<0.005). The grades of extrahepatic uptake were higher in LC than in CAH (spleen: p<0.001, other soft tissue: p<0.005). The early liver/heart uptake rate of CAH (0.110+/-0.111) was significantly higher than that of LC (0.014+/-0.090) (p<0.001). The sensitivity and specificity of the early liver/heart uptake rate were 77.7% and 67.7% in differentiating LC from CAH. There was negative correlation between early liver/heart uptake rate and shunt index (r=-0.3347, p<0.01). CONCLUSION: Hepatic and extrahepatic uptake pattern and early liver/heart uptake rate on T1-201 per rectum scintigraphy are useful in the assessment of portal systemic shunt in patients with chronic liver disease.
Diagnosis ; Heart ; Hepatitis, Chronic ; Humans ; Kidney ; Liver Cirrhosis ; Liver Diseases* ; Liver* ; Portal System ; Radionuclide Imaging* ; Rectum* ; Sensitivity and Specificity ; Spleen

PURPOSE: This study was performed to identify factors affecting the functional status in disabled persons in the Jeju Province. METHOD: Data were collected from 318 disabled persons in the Jeju province during the period from the 6th of July to the 11th of October in 2006. The functional status was assessed by the disability assessment schedule II(Whodas II) of the World Health Organization and collected data were analyzed using the SAS 8.0 program. RESULT: The mean score of WHODAS II was 29.9. According to the results of multiple regression, factors affecting the functional status were perceived health condition(t=3.44, p<.001), brain disorder disability(t=2.55, p<.001), treatment status(t=-1.95, p=.05), drinking(t=2.09, p=.04), stress(t=-2.72, p=.01), depression(t=-2.70, p=.01), heart disease(t=2.62, p=.01) and anemia(t=2.20, p=.03). CONCLUSION: The functional status was affected by health behaviors, diseases, and the type of disability. Thus, future efforts to promote the functional status of disabled persons may need to take into account all these factors.
Appointments and Schedules ; Brain Diseases ; Disabled Persons* ; Health Behavior ; Heart ; Humans ; World Health Organization

No abstract available.
Prostate* ; Testis*

The relationship between the intestinal histopathology and number and position of intraepithelial lymphocytes (IEL) was observed chronologically in the small intestine of rats experimentally infected with Metagonimus yokogawai. Fifteen Sprague-Dawley rats were orally infected each with 3,000 metacecariae, and 3 were kept uninfected for controls. Three rats each were sacrificed on the day 5, 10, 15, 24 and 70 post-infection (PI) and samples of the small intestine, 5 cm, 10 cm, 20 cm and 70 cm posterior to the pylorus were taken. The samples were processed routinely and stained with Giemsa. The intestinal histopathology was severe during the day 5-15 PI and characterized by villous atrophy, crypt hyperplasia, and decrease of villus/crypt height ratio. After the day 24 PI, the intestinal lesions showed some tendency of recovery. The number of IEL increased at the early stage of infection, but decreased thereafter to a lower level than that of controls, with progression of the pathological changes. Then, the IEL number began to increase again after the day 24 PI. In control rats, the great majority of the IEL were located at the basal region of the epithelium. During the early stage of infection, however, a considerable proportion of IEL was found to have moved to the intermediate or apical region of the epithelium. From the above results, it is suggested that the change of IEL number and position during the course of M. yokogawai infection should be closely related to the progression and recovery of the intestinal histopathology.
English-Abstract ; Epithelium-pathology ; Rats- ; Rats,-Sprague-Dawley ; Time-Factors ; *Heterophyidae- ; *Intestinal-Diseases,-Parasitic-pathology ; *Intestines-pathology ; *Lymphocytes-pathology ; *Trematode-Infections-pathology

No abstract available.

Uterine prolapse with pregnancy is rare condition. The overall incidence is 1/10000- 15000 deliveries. The complications from uterine prolapse range from minor cervical ulceration and infection to fetal death or uterine rupture. The fetal mortality was as high as 22% mainly due to prematurity, respiratory infection. The management of this condition is focused on preventing late occurrence of prolapse during pregnancy and continued reduction. We present a case of uterine prolapse in pregnancy with a brief review of the literature.
Fetal Death ; Fetal Mortality ; Incidence ; Pregnancy* ; Prolapse ; Ulcer ; Uterine Prolapse* ; Uterine Rupture