1.A Study on the Frequency of the Autoimmune Disorders in Vitiligo Patients.
Annals of Dermatology 2001;13(4):218-221
BACKGROUND: The increase of the incidence of autoimmune diseases and the autoimmune pathogenesis of vitiligo were reported. OBJECTIVE: We studied the frequency of autoimmune disorders and positivity of antinuclear antibody in Korean vitiligo patients. METHODS: Vitiligo patients (439 patients) and control subjects (197 patients) were interviewed about their history of autoimmune diseases. Laboratory studies including complete blood cell count, urine analysis, blood chemistry, fasting blood sugar, thyroid function test (T3, free T4, TSH), and antinuclear antibody were performed for the screening of autoimmune disorders. RESULTS: The diseases associated with vitiligo were microcytic hypochromic anemia (3.64%), non-insulin dependent diabetes mellitus (2.96%), thyroid disease (3.96%), atrophic gastritis, and alopecia areata. In the control subjects, the associated diseases were microcytic hypochromic anemia (1.62%), non-insulin dependent diabetes mellitus (4.65%), and thyroid disease (3.49%). These results show that the frequency of autoimmune disorders in vitiligo patients is not significantly higher than that in control subjects. Six (54.5%) out of 11 vitiligo patients with thyroid disease were diagnosed as having thyroid disease for the first time. Four (0.91%) out of 438 vitiligo patients showed positive to antinuclear antibody. Positivity of antinuclear antibody was not higher in vitiligo patients than that in control subjects (1.16%). CONCLUSION: Frequency of autoimmune diseases and positive reaction to antinuclear antibody in vitiligo patients were not significantly higher than those in control subjects.
Alopecia Areata
;
Anemia, Hypochromic
;
Antibodies, Antinuclear
;
Autoimmune Diseases
;
Blood Cell Count
;
Blood Glucose
;
Chemistry
;
Diabetes Mellitus
;
Fasting
;
Gastritis, Atrophic
;
Humans
;
Incidence
;
Mass Screening
;
Thyroid Diseases
;
Thyroid Function Tests
;
Vitiligo*
2.Enhancing effect of IL-2, IFN-gamma and poly(A). poly(U) on growth inhibition of murine lymphocytes against cryptococcus neoformans.
Young Min PARK ; Tai You HA ; Byong Suk PARK
Journal of the Korean Society for Microbiology 1991;26(1):105-116
No abstract available.
Cryptococcus neoformans*
;
Cryptococcus*
;
Interleukin-2*
;
Lymphocytes*
3.Efficacy and safety of budesonide turbuhaler in Korean asthmatic patients.
You Young KIM ; Sang Heon CHO ; Kyung Up MIN
Korean Journal of Allergy 1997;17(1):49-57
A controlled study was carried out in 50 patients with perennial bronchial asthma to assess the efficacy and safety of budesonide turbuhaler. Subjects have suffered from cough, wheezing, dyspnea and chest tightness and showed either 15% of reversibility in FEV after bronchodilator inhalation or airway hyperresponsiveness to methacholine(PC20 < or = 25mg/ml.) Patients were randomized to treatment with budesonide turbuhaler or terbutaline turbuhaler for 8 weeks after 2 weeks of run-in period. Budesonide turbuhaler was effective for cough, wheezing, dyspnea and chest tightness. It improved peak expiratory flow rate and FEV1. Budesonide turbuhaler was tolerated well and the laboratory tests showed no abnormality. It is suggested that budesonide turbuhaler is effective and safe in the management of bronchial asthma.
Asthma
;
Budesonide*
;
Cough
;
Dyspnea
;
Humans
;
Inhalation
;
Peak Expiratory Flow Rate
;
Respiratory Sounds
;
Terbutaline
;
Thorax
4.A Case of Multiple Tubular Apocrine Adenoma.
Min Young YOU ; Seok Kweon YUN ; Chull Wan IHM
Korean Journal of Dermatology 2000;38(5):659-663
No Abstract Available.
Adenoma*
5.Modulation of graft-versus-host reaction, IL-6 production and lymphocyte proliforation by bestatin.
Tai You HA ; Jee Kyu KIM ; Young Min PARK ; Me Yae LEE ; Byong Suk PARK
Journal of the Korean Society for Microbiology 1991;26(1):87-104
No abstract available.
Interleukin-6*
;
Lymphocytes*
6.A Case of Trichoblastoma.
You Jeong KIM ; Mi Yeon KIM ; Young Min PARK ; Hyung Ok KIM
Annals of Dermatology 2004;16(4):180-184
No abstract available.
Immunohistochemistry
;
Keratins
7.Familial Isolated Accessory Tragi.
Korean Journal of Dermatology 2008;46(2):238-240
Accessory tragi are an unusual congenital disorder, which are derived from a developmental abnormality of the first branchial arch. They appear at birth as soft or firm skin-colored papules or nodules, usually located in front of the auricle. There was no report of familial accessory tragi in Korean literature. Herein, we present two cases of familial accessory tragi occurring in a brother and a sister.
Branchial Region
;
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
;
Humans
;
Parturition
;
Siblings
8.A case of occupational asthma induced by latexin a hospital personnel.
Byung Jae LEE ; Yoon Keun KIM ; Kyung Up MIN ; You Young KIM
Journal of Asthma, Allergy and Clinical Immunology 1998;18(3):510-517
IgE-mediated sensitization to natural rubber latex can induce immediate hypersensitivity reactions ranging from contact urticaria to life threatening anaphylaxis. Recent reports suggest that asthma is also relatively frequent manifestation of latex allergy. In this case report, lat,ex induced asthma is described in an operat.ing room nurse regularly exposed t,o latex gloves. Her latex sensitivity was detected by skin prick testing. Specific bronchial provocation test with latex extract showed an early asthmatic reaction. Her symptoms had been much improved after avoidance. Occupational asthma induced by latex may be not uncommon among health care workers.
Anaphylaxis
;
Asthma
;
Asthma, Occupational*
;
Bronchial Provocation Tests
;
Delivery of Health Care
;
Humans
;
Hypersensitivity, Immediate
;
Latex
;
Latex Hypersensitivity
;
Personnel, Hospital*
;
Rubber
;
Skin
;
Urticaria
9.Failure of anti-Il-4 antibody to prevent the chicken-gamma globulin-induced active systemic anaphylaxis: involvement of IgG antibodiesin induction of the anaphylaxis.
Tai You HA ; Hern Ku LEE ; Wang Ho LEE ; Kap Sung KIM ; Young Min PARK
Korean Journal of Immunology 1991;13(1):33-41
No abstract available.
Anaphylaxis*
;
Immunoglobulin G*
10.Bilateral Segmental Neurofibromatosis with Partial Unilateral Lentiginosis: Case Report with Review of the Literature.
You Jeong KIM ; Mi Yeon KIM ; Hyung Ok KIM ; Young Min PARK
Annals of Dermatology 2003;15(4):156-159
Bilateral segmental neurofibromatosis is a rare disease characterized by bilateral neurofibromas, with or without pigmented lesion, or unilateral neurofibromas with contralateral pigmented lesion, limited to a body segment. Partial unilateral lentiginosis is characterized by numerous lentigines localized to a body segment, often corresponding to one or more dermatome. Bilateral segmental neurofibromatosis combined with partial unilateral lentiginosis is very rare, and to our knowledge, only 2 cases have been reported in English literature. We herein report another case of bilateral segmental neurofibromatosis with partial unilateral lentiginosis in a 46-year-old woman.
Female
;
Humans
;
Lentigo*
;
Middle Aged
;
Neurofibroma
;
Neurofibromatoses*
;
Neurofibromatosis 1
;
Rare Diseases