1.A Case of Chronic Ectopic Pregnancy Misdiagnosed as Ovarian Cancer.
Journal of the Korean Medical Association 1998;41(11):1183-1187
No abstract available.
Female
;
Ovarian Neoplasms*
;
Pregnancy
;
Pregnancy, Ectopic*
2.Instincts in the Movies.
Journal of the Korean Medical Association 1998;41(2):129-134
No abstract available.
Instinct*
;
Motion Pictures as Topic*
3.Postmenopausal Hormone Replacement Therapy.
Journal of the Korean Medical Association 2000;43(5):412-418
No abstract available.
Estrogen Replacement Therapy*
;
Female
4.Experience of Surgical Approach to the Pontine Lesions : Report of 4 Cases.
Journal of Korean Neurosurgical Society 2000;29(10):1396-1401
No abstract available.
5.The efficacy of fetal genetic diagnosis using fetal nucleated erythrocytes in maternal blood.
Jin CHOI ; Young Min CHOI ; Hee Chul SHIN
Korean Journal of Obstetrics and Gynecology 2000;43(11):1939-1946
OBJECTIVE: The conventional methods to determine fetal genetic status, such as amniocentesis or chorionic villi sampling(CVS) have small procedure-related risk of abortion. Recently, several researchers reported that fetal genetic status, such as sex, can be confirmed by fetal nucleated erythrocytes in maternal blood and this method might reduce such risk. Therefore, in this study, we attempted to determine the basic fetal genetic status, sex, with fetal nucleated erythrocytes. METHODS: In twelve pregnant women who undertook amniocentesis or CVS, 20 ml of venous blood was drawn immediately before the procedure and the nucleated erythrocytes were recovered by magnetic activated cell sorting(MACS). After MACS, DNA was extracted from 200 microliter of sample and single nucleated erythrocyte was obtained by additional procedure, immunostaining, and microdissection. After recovery of nucleated erythrocytes by microdissection, nested polymerase chain reaction(PCR) and fluorescent PCR of amelogenin gene were performed to identify the fetal gender. RESULTS: The DNA of enriched erythrocytes after MACS could identify the fetal gender in the 58.3% of the samples by nested PCR. After the recovery of single nucleated erythrocyte by MACS, immunostaining and microdissection, the minute DNA in a single cell could be amplified by primer extension preamplification(PEP), nested PCR, and fluorescent PCR. Fetal genders were correctly identified in 8 out of 12 (66.7 %). CONCLUSION: Through this study, we could conclude that fetal nucleated erythrocytes in maternal blood might be sufficient sample to determine fetal sex. And single cell isolation by microdissection could get the better results than nested PCR after MACS only. However, in spite of the pregnancy of male fetus, female specific bands were obtained after nested PCR of amelogenin in several cells, which might suggest that part of nucleated erythrocytes in maternal blood might be maternal origin. Therefore, to determine fetal genetic condition by nucleated erythrocytes in maternal blood, further improvements of methods to identify the nucleated erythrocytes of fetal origin are needed.
Amelogenin
;
Amniocentesis
;
Cell Separation
;
Chorionic Villi
;
Diagnosis*
;
DNA
;
Erythroblasts*
;
Erythrocytes
;
Female
;
Fetus
;
Humans
;
Male
;
Microdissection
;
Polymerase Chain Reaction
;
Pregnancy
;
Pregnant Women
6.Treatment of uterine myoma with a gonadotropin-releasing agonist (D-Trp-6-LHRH).
Eung Gi MIN ; Young Min CHOI ; Jin Yong LEE
Korean Journal of Obstetrics and Gynecology 1991;34(5):673-682
No abstract available.
Leiomyoma*
7.A Case of Mixed Gonadal Dysgenesis.
Eun Young CHOI ; Min Sik KIM ; Hey Sun LEE ; Young Min AHN ; Kyung Joon MIN
Journal of the Korean Pediatric Society 1989;32(7):1023-1029
No abstract available.
Gonadal Dysgenesis, Mixed*
8.Arthroscopic Synovectomy in the Rheumatoid Arthritis of the Knee Joint.
Hyun Kee CHUNG ; Choong Hyeok CHOI ; Young Joon CHOI ; Kyeong Jin CHOI ; Jae Min LEE
The Journal of the Korean Orthopaedic Association 1998;33(2):264-272
The short term beneficial effect of arthroscopic excision of synovial tissue in knees with rheumatoid arthritis have been well documented. The purpose of this study to report the results of synovectomy in patients with rheumatoid arthritis who have been observed at least 3 years. We analysed the clinical result with modified Laurin criteria, radiologic change and patients own satisfaction degree with survey. The results were as follows; 1. The preoperative symptoms were pain (100%), swelling (100%), decreased range of motion (83%) and joint tenderness (74%), and those were improved postoperatively to 43%, 60%, 11%, 43% each other. 2. Among the laboratory parameters, C-reactive protein (CRP) was improved most significantly (pvalue =0.026). 3. On simple supine A-P X-rays, the width of medial joint space and lateral joint space were compared to preoperatively and postoperatively. The width of medial joint space was 4.33mm preoperatively, and it was changed to 3.22mm at last follow up (p=0.032). Those of lateral joint space was changed from 4.24mm preoperatively to 3.27mm at last tollow up (p=0.106). 4. The grade of articular cartilage damage was related with severity of preoperative symptoms and the patients with low grade of articular cartilage damage showed more postoperative improvement. The result of operation was related to symptom duration, degree of X-ray change and degree of cartilage damage. 5. 58% ot patients were satisfied to results of synovectomy, 28% were answered neither satisfied nor ansatisfied and 14% were unsatisf'ied to operation. We concluded the arthroscopic synovectomy of the knee joints was effective procedure to improve the clinical symptoms, range of knee motion and to alleviate the inflammatory reaction at mid-term period al'ter the operation. So we consider this procedure is a palliative treatment that modified and alleviate the progression of rheumatoid arthritis of knee joints.
Arthritis, Rheumatoid*
;
C-Reactive Protein
;
Cartilage
;
Cartilage, Articular
;
Follow-Up Studies
;
Humans
;
Joints
;
Knee Joint*
;
Knee*
;
Palliative Care
;
Range of Motion, Articular
9.A Case of Eczema Herpeticum Occurring in Atopic Dermatitis.
Eun Young CHOI ; Min Sik KIM ; Hey Sun LEE ; Young Min AHN
Journal of the Korean Pediatric Society 1989;32(5):695-699
No abstract available.
Dermatitis, Atopic*
;
Eczema*
;
Kaposi Varicelliform Eruption*
10.A Case of Beckwith-Wiedemann Syndrome.
Jeong Wi WOOK ; Eun Young CHOI ; Min Shik KIM ; Hey Sun LEE ; Young Min AHN
Journal of the Korean Pediatric Society 1988;31(12):1685-1688
No abstract available.
Beckwith-Wiedemann Syndrome*