Pulmonary metastasis occurs frequently in patients with gestational choriocarcinoma and most of these patients achieve remission with chemotherapy alone. Thus, the indications for surgical intervention are limited, but in appropriately selected patients, resection of a chemotherapy-resistant lung lesion can be curative. We have experienced that pulmonary metastatic choriocarcinoma in a drug-resistant patient was cured by pulmonary resection. So we report this case with a brief review of literatures.
Choriocarcinoma* ; Drug Therapy ; Female ; Humans ; Lung ; Neoplasm Metastasis ; Pregnancy

A total of 100 Vibrio spp. strains were examined for production of various extracellular enzyme and for plasmid content plasmid were subjected to digestion with restriction enzymes. Most of them produced extracellular enzyme more than one, especially V. parahaemolyticus and V. cholerae non-01 strains were showed production of various extracellular enzymes. About the 55% Vibrio spp. have the plasmid more than one, but a lot of Vibrio spp. (about 45%) did not possess any plasmid. Most of these plasmid various derivatives ranged from 2.4 kb-23 kb, especially two strains of V. mimicus and one strain of V. furnissii carried one high-molecular weight plasmid (molecular weight ranging between 70 kb-100 kb). Results of restriction analysis for plasmid of this three strains were by no means the rule. For detection of tdh and ctx gene, the virulence factor involved in the pathogenesis, we carried out the TDH, CT assay, PCR amplification, and hybridization. A total 11 strains were produced TDH, involved in 4 strains of V. parahaemolyticus and 1 strain of V. cholerae non-01 from clinical isolates and 6 strains of environmental isolates. Nine strains of 11 strains, involved in 4 strains of V. parahaemolyticus and 1 strain of V. cholerae non-01 from clinical isolates and 4 strains of V. parahaemolyticus from environmental isolates, could be successfully amplified in 400 bp by PCR, no amplification products were obtained from TDH-negative strains. The PCR results were consistent with DNA hybridization. In the experiments of ctx gene detection, in all, 3 strains of V. cholerae non-01 from clinical isolate and 1 strains of V. cholerae non-01 from environmental isolate were observed CT- positive. These CT-producing strains amplified in 302 bp by PCR for the detection of ctx gene. All CT-producing strains hybridized with digoxigenin-labeled DNA probe, while CT-negative strains did not hybridize. Also hybridization tests results for detection of ctx gene consistent with PCR.
Cholera ; Digestion ; DNA ; Plasmids ; Polymerase Chain Reaction ; Vibrio* ; Virulence Factors* ; Virulence*

No abstract available.
Ultrasonography, Doppler, Color*

Spinal epidural emphysema is rare and has been described secondary to following medical intervention, such as lumbar puncture and epidural analgesia, pneumothorax or pneumomediastinum, degenerative disk disease, epidural abscess, and trauma. Rarely, it occurs after chest tube placement. We report a case of spinal epidural emphysema incidentally noted on HRCT after chest tube placement.
Analgesia, Epidural ; Chest Tubes ; Emphysema ; Epidural Abscess ; Epidural Space ; Mediastinal Emphysema ; Pneumothorax ; Spinal Puncture ; Subcutaneous Emphysema ; Thorax ; Tomography, X-Ray Computed

Achondrogenesis type 2 is a lethal form of congenital skeletal dysplasia characterized by severe short-limbed dwarfism, decreased vertebral ossification and normal ossification of the skull. We report an autopsy case of achondrogenesis type 2 in a female fetus terminated at 29 weeks of gestation. External morphology revealed a relatively large head, short upper and lower extremities, short neck, and distended abdomen. The x-ray finding showed normal calvarial ossification, hypoplastic ilium and unossified ischium, and metaphyseal flares of the femur and tibia. Histologically, chondrocytes were large and irregular with increased vascularity.
Abdomen ; Autopsy* ; Chondrocytes ; Dwarfism ; Female ; Femur ; Fetus ; Head ; Humans ; Ilium ; Ischium ; Lower Extremity ; Neck ; Pregnancy ; Skull ; Tibia

Pediatric dysphagia comes from disturbances in swallowing process, which has 'preparatory phase', 'oral phase', 'pharyngeal phase', and 'esophageal phase', and mainly the causes are neuro-muscular discoordination. It is necessary to recognize clinical manifestation if they have accompanied organic disorder and diagnose accurately. Videofluoroscopic study evaluation is a valuable method to find out abnormal swallowing mechanism at each phases. Treatment should be diagnosis specific, and multidisciplinary team approach is desirable. We can use various behavioral techniques to facilitate normal swallowing mechanism including conditioning of oral and pharyngeal structures, bolus manipulation, postural compensation, and adaptive feeding utensils. Important point is that the diagnosis and treatment for pediatric dysphagia should not be delayed because children are under development.
Child ; Compensation and Redress ; Deglutition ; Deglutition Disorders ; Humans

No abstract available.
Humans ; Infant, Newborn* ; Precursor Cell Lymphoblastic Leukemia-Lymphoma*

No abstract available.
Child* ; Humans ; Infant* ; Intussusception*

No abstract available.
Child* ; Humans ; Tuberculosis, Renal*

One-hundred ninty five cases with Kawasaki disease who were diagnosed and treated at the Department of Pediatrics, Kyung Hee University Hospital from January 1985 to June 1993, were investigated for their clinical manifestations and laboratory findings, and cardiac complications. The results are as follows: 1) Most patients (92.8%) were under 5 years of the age. 2) Boys were more prevalent than girls, as a ratio of 2.3 : l 3) The incidence of principal symptoms and signs were fever over 5 days (89.8%), bilateral conjunctival injection (78.5%), changes of oral mucosa and lip (82.3%), skin eruption (72.8%), changes in extremities (58.5%), and cervical lymphadenopathy (47.2%). 4) The main laboratory findings observed were anemia (29.2%), leukocytosis (90.8%), thrombocytosis (89.7%), increased ESR (85.1%), positive CRP (100%), increased sGOT (33.3%), increased sGPT (34.9%), pyuria (41.5%), proteinuria (5.6%), microscopic hematuria (9.7%), and abnormalities of EKG (23.5%). 5) Abnormal findings of the heart were found in 27.2% by echocardiogram and coronary aneurysm and dilatation were present in 19.7%. 6) Among 147 cases assessed by echocardiogram, the abnormalities of coronary artery were present in 16 of 92 cases (17.4%) in the aspirin and intravenous gammaglobulin treated group, as compared with 13 of 55 cases (23.6%) in the aspirin treated group.
Alanine Transaminase ; Anemia ; Aspartate Aminotransferases ; Aspirin ; Coronary Aneurysm ; Coronary Vessels ; Dilatation ; Electrocardiography ; Extremities ; Female ; Fever ; Heart ; Hematuria ; Humans ; Incidence ; Leukocytosis ; Lip ; Lymphatic Diseases ; Mouth Mucosa ; Mucocutaneous Lymph Node Syndrome ; Pediatrics ; Proteinuria ; Pyuria ; Skin ; Thrombocytosis