1.A Case of Resection of Pulmonary Metastatic Choriocarcinoma in Drug-Resistant Patient.
Ji Min LEE ; Chi Heum CHO ; Soon Do CHA ; Sang Min CHO ; Kun Young KWON
Korean Journal of Obstetrics and Gynecology 2000;43(6):1096-1099
Pulmonary metastasis occurs frequently in patients with gestational choriocarcinoma and most of these patients achieve remission with chemotherapy alone. Thus, the indications for surgical intervention are limited, but in appropriately selected patients, resection of a chemotherapy-resistant lung lesion can be curative. We have experienced that pulmonary metastatic choriocarcinoma in a drug-resistant patient was cured by pulmonary resection. So we report this case with a brief review of literatures.
Choriocarcinoma*
;
Drug Therapy
;
Female
;
Humans
;
Lung
;
Neoplasm Metastasis
;
Pregnancy
2.The Virulence Factors of Vibrio spp.
Yang Hyo OH ; Young Min PARK ; Min Jung KIM ; Mi Sun CHA
Journal of the Korean Society for Microbiology 1999;34(2):125-136
A total of 100 Vibrio spp. strains were examined for production of various extracellular enzyme and for plasmid content plasmid were subjected to digestion with restriction enzymes. Most of them produced extracellular enzyme more than one, especially V. parahaemolyticus and V. cholerae non-01 strains were showed production of various extracellular enzymes. About the 55% Vibrio spp. have the plasmid more than one, but a lot of Vibrio spp. (about 45%) did not possess any plasmid. Most of these plasmid various derivatives ranged from 2.4 kb-23 kb, especially two strains of V. mimicus and one strain of V. furnissii carried one high-molecular weight plasmid (molecular weight ranging between 70 kb-100 kb). Results of restriction analysis for plasmid of this three strains were by no means the rule. For detection of tdh and ctx gene, the virulence factor involved in the pathogenesis, we carried out the TDH, CT assay, PCR amplification, and hybridization. A total 11 strains were produced TDH, involved in 4 strains of V. parahaemolyticus and 1 strain of V. cholerae non-01 from clinical isolates and 6 strains of environmental isolates. Nine strains of 11 strains, involved in 4 strains of V. parahaemolyticus and 1 strain of V. cholerae non-01 from clinical isolates and 4 strains of V. parahaemolyticus from environmental isolates, could be successfully amplified in 400 bp by PCR, no amplification products were obtained from TDH-negative strains. The PCR results were consistent with DNA hybridization. In the experiments of ctx gene detection, in all, 3 strains of V. cholerae non-01 from clinical isolate and 1 strains of V. cholerae non-01 from environmental isolate were observed CT- positive. These CT-producing strains amplified in 302 bp by PCR for the detection of ctx gene. All CT-producing strains hybridized with digoxigenin-labeled DNA probe, while CT-negative strains did not hybridize. Also hybridization tests results for detection of ctx gene consistent with PCR.
Cholera
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Digestion
;
DNA
;
Plasmids
;
Polymerase Chain Reaction
;
Vibrio*
;
Virulence Factors*
;
Virulence*
3.Clinical study of color doppler ultrasonography in IVF-ET.
Young Beom CHA ; Hong Ki KIM ; Seung Jae LEE ; Jong Min PARK ; Young Ho LEE
Korean Journal of Obstetrics and Gynecology 1991;34(5):697-704
No abstract available.
Ultrasonography, Doppler, Color*
4.Epidural Emphysema Associated with Subcutaneous Emphysema after Chest Tube Placement: A Case Report.
Ji Young RHO ; Seung Min YOO ; Young Ah CHO ; Sang Min LEE
Tuberculosis and Respiratory Diseases 2010;69(5):389-391
Spinal epidural emphysema is rare and has been described secondary to following medical intervention, such as lumbar puncture and epidural analgesia, pneumothorax or pneumomediastinum, degenerative disk disease, epidural abscess, and trauma. Rarely, it occurs after chest tube placement. We report a case of spinal epidural emphysema incidentally noted on HRCT after chest tube placement.
Analgesia, Epidural
;
Chest Tubes
;
Emphysema
;
Epidural Abscess
;
Epidural Space
;
Mediastinal Emphysema
;
Pneumothorax
;
Spinal Puncture
;
Subcutaneous Emphysema
;
Thorax
;
Tomography, X-Ray Computed
5.A Case of Acute Lymphocytic leukemia in a Newborn.
Young Jin MIN ; Myoung Hee CHA ; Kyeng Sook CHO ; Jong Dai JO
Journal of the Korean Pediatric Society 1988;31(9):1197-1201
No abstract available.
Humans
;
Infant, Newborn*
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma*
6.A Clinical Review of Intussusception in Infant and Children.
Myeong Hee CHA ; Young Jin MIN ; Kyeong Sook CHO ; Jong Dae CHO
Journal of the Korean Pediatric Society 1988;31(9):1153-1162
No abstract available.
Child*
;
Humans
;
Infant*
;
Intussusception*
7.Pediatric Dysphagia.
Korean Journal of Pediatric Gastroenterology and Nutrition 2009;12(Suppl 1):S77-S84
Pediatric dysphagia comes from disturbances in swallowing process, which has 'preparatory phase', 'oral phase', 'pharyngeal phase', and 'esophageal phase', and mainly the causes are neuro-muscular discoordination. It is necessary to recognize clinical manifestation if they have accompanied organic disorder and diagnose accurately. Videofluoroscopic study evaluation is a valuable method to find out abnormal swallowing mechanism at each phases. Treatment should be diagnosis specific, and multidisciplinary team approach is desirable. We can use various behavioral techniques to facilitate normal swallowing mechanism including conditioning of oral and pharyngeal structures, bolus manipulation, postural compensation, and adaptive feeding utensils. Important point is that the diagnosis and treatment for pediatric dysphagia should not be delayed because children are under development.
Child
;
Compensation and Redress
;
Deglutition
;
Deglutition Disorders
;
Humans
8.Three cases of atypical Kawasaki disease with coronary aneurysm.
Min Young PARK ; Kwang Sun HAN ; Sung Yoon CHO ; Byoung Soo CHO ; Sung Ho CHA
Journal of the Korean Pediatric Society 1993;36(9):1315-1319
Kawasaki disease is described by fever lasting five days or more, bilateral conjunctival injection, changes of lips and oral cavity, polymorphous exanthema, acute non-purulent cervical lymphadenopathy, and changes of extremities. Atypical Kawasaki disease is defined as fewer than 4 of 6 criteria described above including coronary artery abnormalities. Especially, atypical clinical manifestations of Kawasaki disease appear in infants younger than 6 months old of age. Thus we recommend echocardiography in early infancy who has prolonged fever in order to diagnose atypical Kawasaki disease and treat early. We have experienced three cases of atypical Kawasaki disease with coronary aneurysm who were admitted because of fever and revealed coronary aneurysm on echocardiography.
Coronary Aneurysm*
;
Coronary Vessels
;
Echocardiography
;
Exanthema
;
Extremities
;
Fever
;
Humans
;
Infant
;
Lip
;
Lymphatic Diseases
;
Mouth
;
Mucocutaneous Lymph Node Syndrome*
9.A case of cyclic neutropenia.
Yoon Hwa CHA ; Hye Sun LEE ; Young Min AHN ; Myoung Sook KOO
Journal of the Korean Pediatric Society 1993;36(7):1009-1015
Cyclic Neutropenia is a benign, unusual hematologic disorder characterized by regularly recurring episodes of severe neutropenia occurring approximately every 21 days. Beside neutrophils, monocytes, lymphocytes, platelets and reticulocytes all cycle with strict periodicity suggest that this disease should be viewed as cyclic hematopoiesis, not merely as cyclic neutropenia. During neutropenic periods, patients regularly experience aphthous stomatitis, fever, malaise, cervical lymphadenitis, cutaneous infections and occasional pneumonia and otitis media. The exact cause of cyclic neutropenia is unknown. But it is strongly suggested that cyclic neurtopenia is due to an abnormality in the regulation of early hematopoietic precursor cells. We have documented a case of cyclic neutropenia for a period of 2.5 years in a 11 year-old boy who had suffered from recurrent fever, stomatitis, gingival swelling, cervical lymphadenitis and skin infections at 3 weeks intervals since 5 years of age. A brief review of the related literatures is presented.
Child
;
Fever
;
Hematopoiesis
;
Humans
;
Lymphadenitis
;
Lymphocytes
;
Male
;
Monocytes
;
Neutropenia*
;
Neutrophils
;
Otitis Media
;
Periodicity
;
Pneumonia
;
Reticulocytes
;
Skin
;
Stomatitis
;
Stomatitis, Aphthous
10.Loss of Heterozygosity using Microsatellite Marker in plasma of patients with ovarian cancer.
Yong Min KIM ; Young Tae KIM ; Kyu Wan LEE
Korean Journal of Obstetrics and Gynecology 2002;45(9):1505-1510
OBJECTIVE: Recent studies demonstrated that soluble tumor DNA is found in the plasma of cancer patients, and some microsatellite alteration have been identified in ovarian carcinoma. The aim of study was to detect microsatellite abnormalities in the plasma of patients with ovarian carcinoma and to evaluate their efficacy as molecular screening or diagnostic tool for ovarian cancer. METHODS: In fifteen ovarian carcinoma patients, DNA was extracted from the plasma samples and microsatellite analysis was done with 11 microsatellite markers. RESULTS: All fifteen cases showed at least one tumor specific alteration in microsatellite analysis. The frequency of genetic alteration varies from 14.2% to 85.7%. Highly frequent tumor specfic alteration markers are D18S69 (85.7%), D10S215 (69.2%), D16S504 (66.7%), D8SNEFL (62.5%) and D11S1340 (60.0%). CONCLUSION: These results suggest that the mutation of tumor DNA can be detected in plasma of patients with ovarian carcinoma. LOH is more frequent event and the frequency of genetic alteration is relatively higher than that of previous reports.
DNA
;
Humans
;
Loss of Heterozygosity*
;
Mass Screening
;
Microsatellite Instability
;
Microsatellite Repeats*
;
Ovarian Neoplasms*
;
Plasma*