1.A clinical study on microangiopathic hemolytic anemia.
Jee Sook HAHN ; Don Haeng LEE ; Sun Ju LEE ; Yoo Hong MIN ; Yun Woong KO
Korean Journal of Hematology 1991;26(2):263-279
No abstract available.
Anemia, Hemolytic*
2.Hemichorea Associated with Hyperglycemia: A Case Showing Increased Blood Flow in the Contralateral Striatum.
Chang Min LEE ; Dae Woong YONG ; Sang Hoon HONG
Journal of the Korean Neurological Association 1999;17(5):770-773
We report a diabetic woman who developed paroxysmal hemichorea during an episode of non-ketotic hyper-glycemia. A MRI showed a high signal intensity on T1-weighted images and a low signal intensity on T2-weighted images in the contralateral putamen. SPECT on the 30th day after the onset revealed an increased blood flow in the contralateral striatum. Although these abnormalities in the left putamen are considered to be the cause of her involuntary movement, the exact pathophysiological mechanisms of these abnormalities are not yet clear and further investigations are needed.
Dyskinesias
;
Female
;
Humans
;
Hyperglycemia*
;
Magnetic Resonance Imaging
;
Putamen
;
Tomography, Emission-Computed, Single-Photon
3.Prevalence of hepatitis C virus antibodies in various liver diseases and posttransfusion hepatitis.
Sung Min PARK ; Kee Joong JU ; Chang Hwan LEE ; Young Woong SHIM ; Kap Young SONG
Korean Journal of Medicine 1993;45(2):154-160
No abstract available.
Hepacivirus*
;
Hepatitis C Antibodies*
;
Hepatitis C*
;
Hepatitis*
;
Prevalence*
4.Prevalence and Clinical Features of Probable REM Sleep Behavior Disorder- An Epidemiological Study in Osan City.
Young Min CHOE ; In Young YOON ; Ki Woong KIM ; Sang Don LEE ; Gawon JU ; Joon Hyuk PARK
Sleep Medicine and Psychophysiology 2011;18(1):23-28
OBJECTIVES: REM sleep behavior disorder (RBD) has received little attention in epidemiologic studies. This study aimed to determine the prevalence of probable REM sleep behavior disorder (pRBD) in the elderly population and its clinical features. METHODS: A random sample of 1,588 was selected from a roster of 14,050 elderly population living in Osan city. The subjects were asked to fill out the REM sleep behavior disorder screening questionnaire (RBDSQ). Subjects whose score were 5 or higher on RBDSQ underwent a diagnostic phase of person-to-person assessment by experts in RBD. RESULTS: Among 1,588 subjects, 886 elderly subjects participated in the screening phase and 123 subjects were assessed in the diagnostic phase. Eleven subjects were diagnosed as having pRBD, so prevalence was 1.5% (95% CI=0.70-2.30%). The frequency of depression and cognitive decline was significantly increased in patients with pRBD compared to subjects without pRBD, and there was no difference in sleep disturbances between two groups. CONCLUSIONS: Probable REM sleep behavior disorder is not rare in the elderly but frequently under-recognized. More attention should be paid to evaluation and treatment of RBD.
Aged
;
Depression
;
Epidemiologic Studies
;
Humans
;
Mass Screening
;
Prevalence
;
Surveys and Questionnaires
;
REM Sleep Behavior Disorder
;
Sleep, REM
5.Arthroscopic Decompression of an Inferior Paralabral Cyst of the Shoulder in an Elderly Patient: A Case Report.
Ju Oh KIM ; Ki Yong AN ; Hwang Se BONG ; Kyu Jung LEE ; Woong Bae MIN
Clinics in Shoulder and Elbow 2015;18(4):266-268
The widespread use of diagnostic radiography, especially using magnetic resonance imaging, has helped to increase the diagnosis of paralabral cysts in patients with chronic shoulder pain. These paralabral cysts are frequent in the anterior, the superior, and the posterior compartment of the shoulder joint but are rare in the inferior compartment. Paralabral cysts in the shoulder appear particularly in men in their third and fourth decades but rarely in elderly patients. We report a case of an inferior paralabral cyst in an elderly patient whom we treated through arthroscopic decompression.
Aged*
;
Arthroscopy
;
Decompression*
;
Diagnosis
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Radiography
;
Shoulder Joint
;
Shoulder Pain
;
Shoulder*
6.The effect of the cytotoxicity on cultured fibroblast to various allograft materials.
Seong Hoon CHOI ; In Woong UM ; Dong Keun LEE ; Soo Nam KIM ; Seung Ki MIN
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1992;18(1):111-121
No abstract available.
Allografts*
;
Fibroblasts*
7.Case report of pan-peritonitis due to duodenal ulcer perforation associated with comminuted mandibular fracture.
Dong Keun LEE ; In Woong UM ; Kue Hee KIM ; Seung Ki MIN
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1992;18(1):87-90
No abstract available.
Duodenal Ulcer*
;
Mandibular Fractures*
8.The effect of the cytotoxicity on cultured fibroblast to various type of miniplate.
Book Jung KIM ; In Woong UM ; Dong Keun LEE ; Seung Ki MIN
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1992;18(1):42-52
No abstract available.
Fibroblasts*
9.Therapeutic Outcome and Prognosis in Dlderly Patients with Non - Hodgkin's Lymphoma.
Jee Sook HAHN ; Jin Hyuk CHOI ; Seung Tae LEE ; Yoo Hong MIN ; Yun Woong KO
Journal of the Korean Cancer Association 1999;31(2):320-330
PURPOSE: The prognosis of non-Hodgkins lymphoma (NHL) in elderly patients seems to be poorer than that in patients aged less than 60 years. This may be due to the lower tolerance for combination chemotherapy in the elderly. Aggressive combination chemo-therapy, which is the treatment of choice in intermediate and high grade NHL of adulthood, may be associated with unpredictab1y severe and lethal toxicity and worsened quality of life in the elderly. We investigated the treatment responses, toxicities and prognostic factors of NHL in elderly patients treated with combination chemotherapy. MATERIALS AND METHODS: We treated 116 elderly (>60 yrs) patients with NHL between January 1986 and June 1996 with adriamycin-containing regimens, such as CHOP (cyclo- phosphamide, adriamycin, vincristine, prednisolone), BACOP (bleomycin, adriamycin, cyclophosphamide, vincristine, prednisolone), and mBACOP (methotrexate, bleomycin, adriamycin, cyclophosphamide, vincristine, prednisolone). Patients in this study ranged from 60 to 81 (median 67) years of age. Fifty-five percent of patients were in stage I or II and the rest (45%) were in stage III or IV. The histologic grade was predominantly (91%) of intermediate and high grade type. RESULTS: The treatment responses were complete (CR) in 55% and partial (PR) in 25%. The median durstion of CR was 32 (3-132) months. The CR rate was significantly higher in patients treated with RDI (relative dose intensity) > 75% than that in the patients treated with RDI < 75% (p 0.003), but there was no significant difference in CR rate between treatment regimens (p-0.38). At a median follow up of 48-months (range, 12 to 132 months), the estimated 5-year ovetall survival was 46%. Ann Arbor Stage (I, II vs III, IV), ECOG performance (0-1 vs 2-3), RDI (>75% vs <75%) and the treatment response were important prognostic factors in the univariate analysis, and the treament response (CR vs non-CR) was the only independent prognostic parameter in the multivariate analysis. The most frequent and severe toxicity associated with chemotherapy was infection with or without neutropenia. The rate of severe infection was significantly decreased in the patients supported with G/GM-CSF but not in the dose-reduction group (RDI<75% vs >75%). CONCLUSION: Our data suggests that achievement of the CR after combination chemotherpy is the most important prognostic factor in the elderly patients with NHL. Suboptimal chemotherapy (RDI<75%) reduced the complete remission rate without reducing the likelihood of developing severe toxicities. Optimal chemotherapy with supportive cares involving the use of hematopoietic growth factors may be needed to improve the treatment response and the survival in the elderly patients with aggressive NHL.
Aged
;
Bleomycin
;
Cyclophosphamide
;
Dimethoate
;
Doxorubicin
;
Drug Therapy
;
Drug Therapy, Combination
;
Follow-Up Studies
;
Hodgkin Disease*
;
Humans
;
Intercellular Signaling Peptides and Proteins
;
Lymphoma, Non-Hodgkin
;
Multivariate Analysis
;
Neutropenia
;
Prognosis*
;
Quality of Life
;
Vincristine
10.Familial Occurrence of Moyamoya Disease - Report of Two Cases -.
So Jung MIN ; Youm KIM ; Woong Heum KIM ; Hyun Koo LEE ; Myoung Soo KIM
Korean Journal of Cerebrovascular Surgery 2005;7(1):75-79
Moyamoya disease is a rare occlusive cerebrovascular disease characterized by stenosis or occlusion of the main cerebral arteries. It has a tendency for multifactorial inheritance and familial occurrence, although its pathogenesis is not clear. We observed this disease in two girls from the same family:one was eight years old and the other was 45 months. They presented with transient ischemic attacks. We performed cerebral angiography on both patients and magnetic resonance angiography (MRA) on the younger. Both approaches showed the typical features of moyamoya disease, and MRA successfully revealed abnormal findings specific for the disease in the second child. Both children received encephaloduroarteriosynangiosis (EDAS) and this produced good results. MRA is thus a powerful and noninvasive way of detecting individuals at high risk of developing this disease. Considering the reported familial incidence of moyamoya disease in Japan, a careful search for family members using MRA would probably reveal many more such cases in Korea.
Cerebral Angiography
;
Cerebral Arteries
;
Child
;
Constriction, Pathologic
;
Female
;
Humans
;
Incidence
;
Ischemic Attack, Transient
;
Japan
;
Korea
;
Magnetic Resonance Angiography
;
Moyamoya Disease*
;
Multifactorial Inheritance