1.Prognostic Factors in Liposarcomas: A Retrospective Study of 52 Patients.
Yang Guk CHUNG ; Yong Koo KANG ; Won Jong BAHK ; Seung Koo RHEE ; An Hi LEE ; Jung Mee PARK ; Min Woo KIM
The Journal of the Korean Bone and Joint Tumor Society 2010;16(1):14-20
PURPOSE: To investigate prognostic factors influencing on local recurrence, distant metastasis and event-free survival of liposarcomas. MATERIALS AND METHODS: Fifty-two patients managed for liposarcomas since 1993 were analyzed respectively in the view of prognostic influence of patient age, tumor size, location, histologic type, histologic grade, resection type, surgical margin, chemotherapy and radiation therapy on local recurrence, distant metastasis and event-free survival. The mean follow up period was 39 months. The univariate and multivariate regression analysis were performed for statistical evaluation. RESULTS: The local recurrences occurred in 11 patients (21.2%) and distant metastasis in 4 patients (8%), Event-free survival rate at 4 year follow up was 67%. In univariate analysis, histologic grade, surgical margin, chemotherapy and radiation therapy were significant prognostic factors on local recurrence (p<0.05). However, histologic grade lost its significance in muitivariate analysis. Trunk location revealed higher rate of distant metastasis than extremity location. In univariate analysis on event-free survival. histologic grade and chemotherapy were significant factors (p<0.05). No factor remained significant in multivariate analysis. CONCLUSION: Considering selection bias, positive surgical margin was negative prognostic factor on local recurrence. Liposarcomas arisen in trunk revealed higher rate of distant metastasis. There was no independent prognostic factor on event-free survival of patients with liposarcomas.
Disease-Free Survival
;
Extremities
;
Follow-Up Studies
;
Humans
;
Liposarcoma
;
Multivariate Analysis
;
Neoplasm Metastasis
;
Recurrence
;
Retrospective Studies
;
Selection Bias
2.Hypobaric Spinal Anesthesia in a Patient with Transplanted Heart: A case report.
Sun Joon BAI ; Yong Taek NAM ; Haeng Chul LEE ; Min Woo KOO
Korean Journal of Anesthesiology 1998;35(5):999-1002
Heart transplantation is an accepted procedure for treatment of end-staged cardiac failure. A return to near-normal quality on life can be expected in many patients with a nonrejecting cardiac allograft, and many of these patients will return to the operating room for noncardiac surgical procedures. Anesthesiologists should be alert to recognizing problems caused by the presence of infection in immunosuppressed patients, modes of presentation of rejection phenomena and how transplanted organs, notably significantly denervated ones, may behave and respond under the pathophysiologic circumstance that arise during surgery, resuscitation and intensive care. The use of regional techniques require adequate preloading to avoid exaggerated hypotension and aseptic technique to avoid infection. Hypobaric spinal anesthesia has some benefit. It does not depress cardiovascular and respiratory system and keep adequate venous return by trendelenberg position. We report herein a case of successfully undergone total hip replacement in a patient who had previously undergone orthotopic heart transplantation under hypobaric spinal anesthesia.
Allografts
;
Anesthesia, Spinal*
;
Arthroplasty, Replacement, Hip
;
Heart Failure
;
Heart Transplantation
;
Heart*
;
Humans
;
Hypotension
;
Critical Care
;
Operating Rooms
;
Respiratory System
;
Resuscitation
3.Granuloma Developed Following Injection for Chemical Castration Treatment in Paedophilia.
Yu Ri WOO ; Hye Min LEE ; Joong Sun LEE ; Dae Won KOO ; Kyoung Eun JUNG
Korean Journal of Dermatology 2013;51(5):376-378
No abstract available.
Castration
;
Granuloma
;
Granuloma, Foreign-Body
4.Repair of Microform Cleft Lip with Minimal Incision.
Byung Doo MIN ; Seung Ha PARK ; Eul Sik YOON ; Sang Hwan KOO ; Woo Kyung KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(5):834-837
Microform cleft lip is a mild form of incomplete cleft lip, also known as a minimal occult, abortive, forme fruste cleft lip. However, it has no definition and few methods have been reported for its correction. A microform cleft lip is characterized as the incomplete union of the superficial portion of the orbicularis oris muscle. It is more prominent during facial expression than in a resting state. We confined microform cleft lip in our study to the absence of philtral skin change and a contracted position on the top of cupid's bow. During the past 5 years, 17 patients of microform cleft lip were operated on. We corrected the defect of the upper vermilion border and nostril sill with minimal incision, and repaired the underlying lip musculature in superficial discontinuity. Reduction of the widened alar base was performed. Deformed alar cartilage was dissected via rim incision, and suspended in a medial and upper direction with pull-out sutures. The most important thing is precise repair of the superficial portion of the separated orbicularis oris muscle via minimal incision, and it is best to operate after 1-year of age for accurate repair. The results were satisfactory and the parents were also satisfied. The advantages of this procedure are as follows: 1. Less visible, minimal scar on upper lip 2. Simultaneous correction of vermillion notching, deformed cupid's bow and nasal deformity. 3. Eversion of philtral ridge due to tenting effect of horizontal mattress suture 4. Philtral elongation effect by reduction of alar base and Z-plasty of cupid's bow.
Cartilage
;
Cicatrix
;
Cleft Lip*
;
Congenital Abnormalities
;
Facial Expression
;
Humans
;
Lip
;
Microfilming*
;
Parents
;
Skin
;
Sutures
5.A clinical study of mycotic sinusitis.
Yang Gi MIN ; Myung Koo KANG ; Jong Woo LEE ; Moo Jin CHOO ; Kang Soo LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(2):292-301
No abstract available.
Sinusitis*
6.Surgical treatment of metastatic tumor of spine musculoskeletal oncology study group.
Young Kyun WOO ; Seung Koo RHEE ; Hyoung Min KIM ; Yong Koo KANG ; Suk Whan SONG ; Won Jong BAHK ; Chong Hoo KANG ; Seung Beom KANG
The Journal of the Korean Orthopaedic Association 1993;28(5):1774-1782
No abstract available.
Spine*
7.Hypercalcemia Associated with Bone Metastasis
Won Jong BAHK ; Ju Hai CHANG ; Seung Koo LEE ; Myung Sang MOON ; Young Kyun WOO ; Jung Man KIM ; Hyoung Min KIM ; Yong Koo KANG ; Seok Whan SONG
The Journal of the Korean Orthopaedic Association 1995;30(2):349-354
Hypercalcemia is a relatively common complication of cancer that is clinically important because, left unattended, it is associated with symptomatic deterioration and even death. So hypercalcemia can afflict the quality of life and complicate management of the cancer patients with anorexia, lethargic, stuporous mentality, and severely dehydrated. Nonetheless, most cancers are at an advanced stage by the time hyperclacemia develops, many clinicians share doubts about the role of antihypercalcemic therapy in this situation. Furthermore, because the symptoms of hypercalcemia may mimic that of progressive malignant disease or the toxic effects of chemotherapy and radiation therapy, this may not always be recognized. So concerns are needed for active management of patients with malignant hypercalcemia. The authors reviewed the morbidity and mortality in 20 patients with malignant hypercalcemia out of 219 patients with bone metastasis, who were treated at the department of orthopaedic surgery, Catholic University Medical College from January 1989 through December 1992. The results were as follows. 1. The overall incidence of malignant hypercalcemia was 8.6% of bone metastases (20 out of 219 cases).: lung cancer 11.2% (10 out of 89 cases), breast cancer 22.5% (7 out of 31 cases), stomach cancer 6.3% (3 out of 47 cases). 2. The underlying diseases associated with hyprecalcemia were 10 cases of lung cancer(50%), 7 cases of breast cancer(35%) and 3 cases of stomach cancer(15%). Out of lung cancers, 8 cases were squamous cell cancers, the other 2 cases were oat cell cancers. 3. Only 7 out of 20 patients were treated with hydration, diuretics, steroid, calcitonin and mithramycin. And the mean survival duration after recognition of hypercalcemia was 11.3 weeks independent of treatment. In conclusion, the authors emphasize that inspite of grave prognosis, when treated actively, calcium lowering therapy may allow patients to be discharged during terminal period of their illness.
Anorexia
;
Avena
;
Breast
;
Breast Neoplasms
;
Calcitonin
;
Calcium
;
Diuretics
;
Drug Therapy
;
Humans
;
Hypercalcemia
;
Incidence
;
Lung
;
Lung Neoplasms
;
Mortality
;
Neoplasm Metastasis
;
Neoplasms, Squamous Cell
;
Plicamycin
;
Prognosis
;
Quality of Life
;
Stomach
;
Stomach Neoplasms
;
Stupor
8.Periampullary cancer and whipple's operation.
Ja Yun KOO ; Woo Jung LEE ; Sung Hoon NO ; Myung Wook KIM ; Byung Ro KIM ; Jin Sik MIN ; Kyung Sik LEE
Journal of the Korean Surgical Society 1992;43(4):518-528
No abstract available.
9.A Case of Global Aphasia without Hemiparesis.
Yong Tae KWAK ; Il Woo HAN ; Hee CHEONG ; Min Seong KOO
Journal of the Korean Neurological Association 2000;18(1):73-76
In addition to severe deficits in speech production and auditory comprehension, patients with global aphasia general-ly have a dense hemiplegia. However, acute global aphasia without hemiparesis (GAWH) occurs rarely and only a few cases of GAWH have been reported with variable conclusions regarding lesion localization, etiology, and prognosis. We report an unusual case of GAWH in which magnetic resonance imaging (MRI) and single photon emission comput-ed tomography (SPECT) revealed only a single lesion of the left superior temporal area. Our case supports the notion that the functional anatomy of aphasia may be complex and that GAWH may have a more benign prognosis than typi-cal global aphasia with hemiparesis.
Aphasia*
;
Comprehension
;
Hemiplegia
;
Humans
;
Magnetic Resonance Imaging
;
Paresis*
;
Prognosis
;
Tomography, Emission-Computed, Single-Photon
10.The Effect of Low-Dosage Alpha-Interferon Therapy in Children with Chronic Active Hepatitis B.
Hee Kyung KIM ; Sung Min CHOI ; Cheol Woo KO ; Kun Soo LEE ; Ja Hoon KOO ; Doo Hong AHN
Journal of the Korean Pediatric Society 1990;33(7):915-922
No abstract available.
Child*
;
Hepatitis, Chronic*
;
Humans
;
Interferon-alpha*