Eleven cases of arthroscopic ankle arthrodesis were reviewed. Average age of patients was 59 years, 4 male and 7 female. Underlying diseases were osteoarthritis in 7 cases, rheumatoid arthritis in 3 cases and one post-traumatic arthritis. At the mean follow up of 15 months, fusion rate was 100%, mean time to complete union was 9.5 weeks. There were no complications such as nonunion, infection and skin problems. All patients stayed at the hospital just overnight after the surgery. Patients satisfaction was high and the functional clinical grade was excellent in 9 patients, good in 1 patient and fair in 1 patient. We concluded that arthroscopic technique was a simple and effective method for ankle arthrodesis in the selected patients and had significant advantages over the open technique.
Ankle* ; Arthritis ; Arthritis, Rheumatoid ; Arthrodesis* ; Arthroscopy ; Female ; Follow-Up Studies ; Humans ; Male ; Osteoarthritis ; Skin

Objective To explore the impact of maternal hepatitis B (HBV) virus infection status on the vaccination effect of the offspring. Methods Eighty-six pairs of HBV-infected mothers and newborns who were treated in Dalian Sixth People<sup>'sup>s Hospital from 2017 to 2019 were selected as the research subjects. According to the strength of the hepatitis B vaccine response, all patients were divided into two groups, the observation group (none or weak response) and the control group (strong response). Hepatitis B virus infection was compared between the mothers of the two groups, and multivariate logistic regression was used to analyze the influencing factors of vaccination effect of the offspring. Results The positive rate of HBV DNA in mothers of the observation group was higher than that in the control group. HBV DNA was mainly at high load and HBeAg was at low level. The HBV DNA of the control group was mainly at low load, while the distribution of HBeAg was close. The difference was statistically significant (P < 0.05). HBV infection pattern in the observation group was <sup>"sup>HBsAg(+), HBeAg(+), anti-HBc(+)<sup>"sup> in 14 cases (51.85%), <sup>"sup>HBsAg(+), anti-HBe(+), anti- HBc(+)<sup>"sup> in 11 cases (40.74%) , while there were 27 cases (45.76%), 25 cases (42.37%), and 7 cases (11.86%), respectively, in the control group. The difference was statistically significant (P<0.05). Multivariate logisitic regression analysis showed that HBV DNA positivity, HBV DNA high load, HBeAg positivity, and low HBeAg levels were risk factors for weak response of the offspring vaccination. Conclusion HBV DNA positivity, high HBV DNA load, HBeAg positivity, and low HBeAg levels in HBV-infected mothers were risk factors for weak response of the offspring to vaccines, which should be paid attention to in clinic.

OBJECTIVES: This study aims to investigate the effectiveness of an internet-based anger management program for school-aged children. METHODS: Forty-eight elementary school students took part in an anger management training program; subsequently, participants, their parents, and their teachers answered questionnaires assessing the participants' anger, aggressiveness, and other emotional/behavioral problems, pre- and post-training. RESULTS: At the post-training self-assessment, the participants showed significant reductions in their "anger-out" tendencies and physical aggressiveness. In addition, the effects of the program on "anger-out" tendencies, aggressiveness, anger and peer relational problem were found to be more significant in participants who reported depressive symptoms. Teachers rated the participants' peer-relational problems as having decreased after the training. CONCLUSION: The proposed internet-based anger management program had a significant effect on the school-aged children's abilities to control their anger.
Anger* ; Child* ; Depression ; Education ; Humans ; Parents ; Self-Assessment ; Violence* ; Surveys and Questionnaires

PURPOSE: The efficacy of 20-gauge and 23-gauge vitrectomy system was investigated in primary vitrectomy for rhegmatogenous retinal detachment. METHODS: Eyes that underwent primary vitrectomy without scleral buckling for the treatment of rhegmatogenous retinal detachment were followed up at least 6 months and were reviewed retrospectively. Anatomic results, functional outcomes, operation time and complications were compared between 20-gauge and 23-gauge groups. RESULTS: Among 59 eyes of 59 patients, the 20-gauge group had 29 eyes of 29 patients and 23-gauge group had 30 eyes of 30 patients. Anatomic success after a single operation was obtained in 23 eyes (79.3%) of the 20-gauge group and 28 eyes (93.3%) of the 23-gauge group. Recurrence occurred in 6 eyes (20.7%) in the 20-gauge and in 2 eyes (6.6%) in the 23-gauge group. Retinal reattachment in all of these eyes was obtained through reoperation. Visual acuity improved logMAR 0.2 or more in 19 eyes (65.5%) of the 20-gauge group and 20 eyes (66.7%) of the 23 gauge group (p=0.153, 0.215). The average operation time of the 23-gauge group was 80.2 minutes, which was significantly shorter than the 94.8 minutes of the 20-gauge group (p=0.008). Transient ocular hypertension and progression of lens opacity were the most common complications in the both groups. CONCLUSIONS: Twenty-three-gauge transconjuctival sutureless vitrectomy achieved outcomes comparable with 20-gauge vitrectomy, with significantly shorter operation time in repair of rhegmatogenous retinal detachment. It is considered as a viable alternative to 20-gauge vitrectomy in selected cases.
Cataract ; Eye ; Humans ; Ocular Hypertension ; Recurrence ; Reoperation ; Retinal Detachment ; Retinaldehyde ; Retrospective Studies ; Scleral Buckling ; Visual Acuity ; Vitrectomy

PURPOSE: To compare the changes in corneal topography between 23 gauge (G) pars plana vitrectomy (PPV) and 20 G PPV. METHODS: Forty-three eyes of 42 patients who underwent PPV were divided into 2 groups: 20G PPV (Group I, n=18) and 23 G PPV (Group II, n=25). Both groups were followed up over 3 months postoperatively. ORBSCAN II was performed to compare the corneal topographic change of 20 G PPV and 23 G PPV. RESULTS: In a 5 mm zone, significant postoperative change in the mean corneal surface cylinder was found between the 1st day and the 1st month in Group I, while no significant change was found in Group II. Postoperatively, the increase in the mean corneal surface cylinder in Group I was significantly higher than in Group II between the 1st day and the 1st month. Clinically significant astigmatism, induced by surgery, was found only in Group I one week after the operation. In a 3 mm zone, there was no significant change in the mean corneal surface cylinder in both groups postoperatively. The difference in the mean corneal surface cylinder between the 2 groups at the postoperative periods showed no significant change. Surgically induced astigmatism was significantly higher in Group I than in Group II between the 1st day and the 1st month postoperatively. CONCLUSIONS: PPV with the 23 G system is a sutureless transconjunctival surgery, which appears to be more effective due to insignificant corneal surface and astigmatic changes in the early postoperative period.
Astigmatism ; Corneal Topography ; Eye ; Humans ; Postoperative Period ; Vitrectomy

No abstract available.
Child* ; Humans ; Liver Diseases* ; Liver* ; Prospective Studies*

There are some controversies on the mechanism of the lumbar disc degeneration and disc prolapse. But,it is clear that many factors are related to the disc degeneration. Configurations of the lower lumbar and lumbosacral spine have long been proposed as one of the important factors of disc degeneration in these areas. To look for the configurational risk factors and the probability of disc degeneration by the combinations of these factors, we analyzed simple radiographs and MRI of 73 patients who complaints of low back pain and are between 20 years and 39 years of age. We performed chi-square test and multivariate logistic regression analysis: L4-5 disc degeneration and L5-Sl disc degeneration as dependent variables and lumbar lordosis, sacral inclination, height of intercrest line, transitional vertebra and facet joint asymmetry as independent variables. We could not find any of these variables significantly related to the L4-5 intervertebral disc degeneration. For L5-S1 disc degeneration, only the presence of transitional vertebra was signicantly related. When there is no transitional vertebra, the probability of disc degeneration is 9 times(8.889) as large as that of presence of transitional vertebra. The probability of L4-5 disc degeneration without the degeneration of L5-S1 is 3 times as large as that of degeneration of both of L4-5 and L5-S1 disc in case of the presence of transitional vertebra.
Animals ; Humans ; Intervertebral Disc Degeneration* ; Logistic Models ; Lordosis ; Low Back Pain ; Magnetic Resonance Imaging ; Prolapse ; Risk Factors ; Spine* ; Zygapophyseal Joint

PURPOSE: To assess the prognostic factors associated with anatomical success of scleral buckle (SB) for rhegmatogenous retinal detachment (RRD) in high myopia patients. METHODS: The medical records of RRD in highly myopic eyes treated with SB from January 2009 to December 2013 were reviewed retrospectively. Cases with history of intraocular surgery including phacoemulsification and vitrectomy were excluded. Correlations between anatomical success and the parameters of age, sex, preoperative visual acuity, axial length, presence of large tear, presence of horseshoe tear, the number of tears, involved fovea, and extent of detachment were analyzed. RESULTS: This study included 80 eyes of 80 patients. Average age and axial length were 32.3 ± 13.4 and 26.753 ± 0.961 mm, respectively. Sixty-nine eyes (86.3%) were reattached following primary surgery. Univariate analysis revealed that age (p = 0.011), presence of large tear (p = 0.002), and presence of horseshoe tear (p = 0.044) were correlated with anatomical success after SB. Based on multivariate logistic regression analysis, age was the sole independent prognostic factor (odds ratio = 1.086, 95% confidence interval = 1.022~1.154, p = 0.004). CONCLUSIONS: A younger age is associated with a higher rate of primary anatomical success of SB for RRD in highly myopic eyes. In young, highly myopic patients with RRD, SB should be considered as the primary procedure.
Humans ; Logistic Models ; Medical Records ; Myopia ; Phacoemulsification ; Retinal Detachment* ; Retinaldehyde* ; Retrospective Studies ; Scleral Buckling* ; Tears ; Visual Acuity ; Vitrectomy

Leber's hereditary optic neuropathy (LHON) is a maternally transmitted disease causing acute or subacute, bilateral optic atrophy mainly in young men. It is found to be a mitochondrial disorder with the primary mitochondrial DNA (mtDNA) mutations at 11778, 3460, and 14484. The incidence of each mutation is reported to be race-dependent. Point mutations at mtDNA nucleotide position 11778 and 14484 have been reported in Korean patients with LHON, however there has been no report of mtDNA mutation at nucleotide position 3460. Molecular genetic analyses at four primary sites (11778, 14484, 15257, and 3460) of mitochondrial DNA using the polymerase chain reaction, restriction enzyme digestion, and direct sequencing were performed in a 35-yr-old man with severe visual loss. A point mutation in the mtDNA at nucleotide position 3460 was identified and a conversion of a single alanine to a threonine was confirmed. To our knowledge, this is the first report confirming mtDNA mutation at nucleotide position 3460 in Korean patients with LHON. Detailed molecular analyses would be very helpful for the correct diagnosis of optic neuropathy of unknown etiology and for genetic counseling.
Adult ; *DNA, Mitochondrial ; Humans ; Male ; Optic Atrophy, Hereditary, Leber/*genetics ; *Point Mutation

PURPOSE: To compare concentration of cytokines in the vitreous of rabbit eyes after photocoagulation using a short-pulse pattern scanning laser (PASCAL) or a conventional laser. METHODS: Laser photocoagulation was performed using PASCAL (duration 0.02 seconds) in the right eyes and a conventional laser (duration 0.1 seconds) in the left eyes of 13 pigmented rabbits. To obtain ophthalmoscopically similar mild burns, power was adjusted during the photocoagulation. The rabbits were sacrificed at 1, 3 or 7 days after photocoagulation to investigate histological changes. Levels of interleukins (IL)-1beta, IL-6, IL-8 and tumor necrosis factor (TNF)-alpha in the vitreous humors of ten rabbits were measured using enzyme-linked immunosorbent assay before treatment and at 1, 3 and 7 days after photocoagulation. RESULTS: Histological changes were comparable between the two groups. IL-1beta and TNF-alpha were not detectable. IL-6 did not change significantly. IL-8 increased at day 3 and day 7, but no significant difference was observed between the two groups (p>0.05). CONCLUSIONS: When ophthalmoscopically similar mild burn intensity was achieved, conventional and PASCAL treatments of rabbit eyes caused no difference in intravitreal concentration of inflammatory cytokines.
Burns ; Cytokines* ; Enzyme-Linked Immunosorbent Assay ; Interleukin-6 ; Interleukin-8 ; Interleukins ; Light Coagulation* ; Rabbits* ; Tumor Necrosis Factor-alpha ; Vitreous Body