1.A Study on Physiological Index, Anxiety and Depression by the Severity of Lower Urinary Tract Symptoms in Patients with Benign Prostatic Hyperplasia.
Jung Kyoun KIM ; Jin Bum KIM ; Min Sun SONG
Journal of Korean Biological Nursing Science 2016;18(3):127-134
PURPOSE: The purpose of this study was to investigate the physiological index, anxiety and depression by the severity of lower urinary tract symptoms in patients with benign prostatic hyperplasia. METHODS: This research was conducted from the 4th to the 27th of May in 2016 on112 patients with benign prostatic hyperplasia. The data were analyzed using a chi-square test, ANOVA, and Pearson Correlation Coefficients. RESULTS: The results demonstrated a difference depending on the dysuria period of each lower urinary tract symptom, marital status, occupation and perceived health state of the patient. The physiological index by lower urinary tract symptoms showed a difference in the maximum flow rate, amount of post-void residual urine and Prostate-Specific Antigen (PSA), and anxiety and depression factors also revealed a difference. Lower urinary tract symptoms showed a positive correlation to the amount of post voided residual urine and PSA, a negative correlation to the maximum flow rate and also indicated a positive correlation to depression. CONCLUSION: The results of the study belonging to the moderate and severe categories were high when the result was based on the categorization of subjects with benign prostatic hyperplasia with lower urinary tract symptoms. Considering that depression levels increase as the symptom intensifies and the anxiety score is also high with mild symptoms, psychological support intervention is needed when a pattern of benign prostatic hyperplasia appears.
Anxiety*
;
Depression*
;
Dysuria
;
Humans
;
Lower Urinary Tract Symptoms*
;
Marital Status
;
Occupations
;
Prostate-Specific Antigen
;
Prostatic Hyperplasia*
;
Urinary Tract
2.Pathophysiological study on the anemia in hypothyroidism.
Jee Sook HAHN ; Sun Ju LEE ; Hyun Chul LEE ; Yoo Hong MIN ; Kap Bum HUH ; Yun Woong KO
Korean Journal of Hematology 1992;27(1):1-14
No abstract available.
Anemia*
;
Hypothyroidism*
3.Development of Multicolor Fluorescence In Situ Hybridization for Preimplantation Genetic Diagnosis in Human Embryos.
Suk Hyun KIM ; Sung Mi CHOI ; Hee Sun KIM ; Bum Yong RYU ; Myung Geol BANG ; Sun Gyung OH ; Byung Chul JEE ; Chang Suk SEO ; Young Min CHOI ; Gwang Bum BAE ; Jung Goo KIM ; Sin Yong MOON ; Jin Yong LEE
Korean Journal of Obstetrics and Gynecology 2000;43(12):2170-2177
No abstract available.
Embryonic Structures*
;
Fluorescence*
;
Humans*
;
In Situ Hybridization*
;
Preimplantation Diagnosis*
4.Cardiac Tamponade Caused by Cardiac Hemangioma: A case report.
Won Chae JANG ; Byong Pyo KIM ; Yong Sun CHOI ; Min Sun BUM ; Bong Suk OH
The Korean Journal of Thoracic and Cardiovascular Surgery 2005;38(3):233-236
Cardiac hemangioma is an extremely rare benign tumor. A 65 years old woman was admitted due to epigastric and chest pain. After we confirmed cardiac tamponade with right atrial mass by chest CT, we performed surgical resection of the mass and identified hemangioma with capillary endothelial hyperplasia on pathologic examination. Therefore, we report the case with literature review.
Aged
;
Capillaries
;
Cardiac Tamponade*
;
Chest Pain
;
Female
;
Heart Neoplasms
;
Hemangioma*
;
Humans
;
Hyperplasia
;
Tomography, X-Ray Computed
5.Displaced Double-Layered Lateral Meniscus That Mimicked the Bucket-Handle Tear: a Case Report.
Min Jee KWAK ; Sun Ki KIM ; Ki Jun KIM ; Bum Sik LEE ; Jun KANG
Investigative Magnetic Resonance Imaging 2016;20(3):191-195
Among the various types of congenital meniscal anomalies, the double-layered lateral meniscus is extremely rare. The double-layered meniscus consists of both the upper additional and the lower normal meniscus. As the upper additional meniscus is mobile, it can be easily displaced, while the lower lateral meniscus is usually normal in shape and volume. A 42-year-old woman suffering from pain and locking of her left knee underwent Magnetic resonance imaging (MRI) examination and an arthroscopic surgery. A rare meniscal abnormality was seen in her left knee, which presented as a double-layered lateral meniscus with displacement. It was remarkable that the upper additional meniscus was displaced over the intercondylar eminence of the tibia and it mimicked a bucket-handle tear. Even though it is rare, it is necessary to consider the possibility of displaced double-layered meniscus in the differential diagnosis of a bucket-handle tear. Here, we report the MRI and arthroscopic findings of a displaced double-layered lateral meniscus, which was similar to the bucket-handle tear.
Adult
;
Arthroscopy
;
Diagnosis, Differential
;
Female
;
Humans
;
Knee
;
Magnetic Resonance Imaging
;
Menisci, Tibial*
;
Tears*
;
Tibia
6.The Results of Extraventricular Drainage Combined with Intraventricular Injection of Urokinase for Intraventricular Hematomas.
Young Sun CHUNG ; Min Ho KIM ; Ji Young LEE ; Ki Bum SIM ; Seung Kuan HONG
Journal of Korean Neurosurgical Society 1996;25(4):812-818
The authors applied extraventricular drainage combined with intermittent intraventricular injection of urokinase to 21 patients with intraventricular hemtoma and ventricular dilatation. Ten-thousand IU of urokinase was injected every 12 hours for 3 days. Follow-up CT on day 4 after the treatment showed complete disappearance of the hematoma in the 3rd and 4th ventricles and a small residual hematoma in the occipital horns of lateral ventricles in the majority(14 patients) of the patients. Obstruction of the drainage catheter did not occur in any case, but transient pleocytosis in CSF study, ventriculitis, and rebleeding complicated 6,4, and 4 cases, respectively. The duration of extraventricular drainage in the 17 patients without major complications was 3-17 days. The clinical and death in 7 cases. The decisive events that were thought to have caused vegetative states or death in the 13 case. The method of extraventricular drainage combined with intermittent intraventricular injection of urokinase seems useful in revoving intraventricular hematomas, futher investigation including prospective studies is necessary to determine whether the intraventricular injection of urokinase significantly improves the final outcomes of those patients with severe intraventricular hematomas.
Animals
;
Catheters
;
Dilatation
;
Drainage*
;
Follow-Up Studies
;
Hematoma*
;
Horns
;
Humans
;
Injections, Intraventricular*
;
Lateral Ventricles
;
Leukocytosis
;
Persistent Vegetative State
;
Urokinase-Type Plasminogen Activator*
7.Who experiences endoscopic retrograde cholangiopancreatography after laparoscopic cholecystectomy for symptomatic gallstone disease?.
Bum Soo KIM ; Sun Hyung JOO ; Sungsin CHO ; Min Soo HAN
Annals of Surgical Treatment and Research 2016;90(6):309-314
PURPOSE: Laparoscopic cholecystectomy (LC) has become a standard treatment of symptomatic gallstone disease. But, some patients suffer from retained common bile duct stones after LC. The aim of this study is to analyze the predicting factors associated with subsequent postoperative endoscopic retrograde cholangiopancreatography (ERCP) after LC. METHODS: We retrospectively reviewed a database of every LC performed between July 2006 and September 2012. We classify 28 patients who underwent ERCP within 6 months after LC for symptomatic gallstone disease as the ERCP group and 56 patients who underwent LC for symptomatic gallstone disease during same period paired by sex, age, underlying disease, operation history, and body mass index as the control group. To identify risk factor performing postoperative ERCP after LC, we compared admission route, preoperative biochemical liver function test, number of gall stones, gallstone size, adhesion around GB, wall thickening of GB, and existence of acute cholecystitis between the 2 groups. RESULTS: Admission route, preoperative AST, ALT, and ALP, stone size, longer operation time, and acute cholecystitis were identified as risk factors of postoperative ERCP in univariate analyses. But, longer operation time (P = 0.004) and acute cholecystitis (P = 0.048) were identified as independent risk factors of postoperative ERCP in multivariate analyses. CONCLUSION: The patient who underwent ERCP after LC for symptomatic gallstone disease are more likely experienced longer operation time and acute cholecystitis than the patient who did not undergo ERCP after LC.
Body Mass Index
;
Cholangiopancreatography, Endoscopic Retrograde*
;
Cholecystectomy, Laparoscopic*
;
Cholecystitis, Acute
;
Common Bile Duct
;
Gallstones*
;
Humans
;
Liver Function Tests
;
Multivariate Analysis
;
Retrospective Studies
;
Risk Factors
8.Follow-up Results of Stent Placement for Extracranial Carotid Artery Stenosis.
Young Sup YOON ; Bum Kee HONG ; Dong Hoon CHOI ; Sun Ho KIM ; Dong Ik KIM ; Seung Min KIM ; Yangsoo JANG ; Won Heum SHIM
Korean Circulation Journal 1998;28(11):1820-1927
BACKGROUND AND OBJECTIVES: Carotid artery stenting has evolved as a potential alternative to carotid endarterectomy in patients (pts) with significant carotid artery stenosis. We evaluated the feasibility and long-term outcome of carotid artery stenting in selected pts at high surgical risk. MATERIALS AND METHODS: Between May, 1996 and September 1998 we performed carotid artery stenting at 35 lesions in 25 pts. There were 23 males and 2 fe-males. Mean age was 63.2+/-6.6 (range 54 - 77). Eight four percent (21/25) of the pts had significant coronary artery disease. Sixty four percent (16/25) of the pts had significant peripheral artery lesions. Sixty percent (15/25) of the pts had neurologic symptoms or non-disabling stroke. We used Wallstent in 32 lesions and Palmaz stent in 3 lesions. Carotid stenting was undertaken in 33 internal carotid, 1 common carotid and 1 external carotid lesions. Bil-ateral carotid stenting was undertaken in forty percent (10/25) of the pts. RESULTS: Carotid stenting was successful in all lesions. One patient died due to massive cerebral hemorrhage 3 days after carotid stenting, who had und-erwent stenting as a rescue procedure for failed endarterectomy. One major stroke developed during procedure with partial recovery. For the combined endpoint of strokes and death within 30 days of procedure, the incidence was 8% and 5.7% in terms of pts and procedures, respectively. On follow-up (12+/-7 months), we found neither neurologic complications nor death. Angiographic and/or duplex sonography which were performed at 5.5 month in all (18) eligible pts with 24 lesions revealed no evidence of stent deformity or restenosis ( 50% of diameter stenosis). Mean angiographic stenosis was 20% on follow-up angiography. CONCLUSION: Carotid artery stenting can be performed with high success and low complication rate in pts with significant carotid artery stenosis especially at high surgical risk. Follow-up clinical outcome of average 12 month was good with low restenosis rate.
Angiography
;
Arteries
;
Carotid Arteries*
;
Carotid Stenosis*
;
Cerebral Hemorrhage
;
Congenital Abnormalities
;
Constriction, Pathologic
;
Coronary Artery Disease
;
Endarterectomy
;
Endarterectomy, Carotid
;
Follow-Up Studies*
;
Humans
;
Incidence
;
Male
;
Neurologic Manifestations
;
Stents*
;
Stroke
9.The large-conductance calcium-activated potassium channel holds the key to the conundrum of familial hypokalemic periodic paralysis.
June Bum KIM ; Sung Jo KIM ; Sun Yang KANG ; Jin Woong YI ; Seung Min KIM
Korean Journal of Pediatrics 2014;57(10):445-450
PURPOSE: Familial hypokalemic periodic paralysis (HOKPP) is an autosomal dominant channelopathy characterized by episodic attacks of muscle weakness and hypokalemia. Mutations in the calcium channel gene, CACNA1S, or the sodium channel gene, SCN4A, have been found to be responsible for HOKPP; however, the mechanism that causes hypokalemia remains to be determined. The aim of this study was to improve the understanding of this mechanism by investigating the expression of calcium-activated potassium (KCa) channel genes in HOKPP patients. METHODS: We measured the intracellular calcium concentration with fura-2-acetoxymethyl ester in skeletal muscle cells of HOKPP patients and healthy individuals. We examined the mRNA and protein expression of KCa channel genes (KCNMA1, KCNN1, KCNN2, KCNN3, and KCNN4) in both cell types. RESULTS: Patient cells exhibited higher cytosolic calcium levels than normal cells. Quantitative reverse transcription polymerase chain reaction analysis showed that the mRNA levels of the KCa channel genes did not significantly differ between patient and normal cells. However, western blot analysis showed that protein levels of the KCNMA1 gene, which encodes KCa1.1 channels (also called big potassium channels), were significantly lower in the membrane fraction and higher in the cytosolic fraction of patient cells than normal cells. When patient cells were exposed to 50 mM potassium buffer, which was used to induce depolarization, the altered subcellular distribution of BK channels remained unchanged. CONCLUSION: These findings suggest a novel mechanism for the development of hypokalemia and paralysis in HOKPP and demonstrate a connection between disease-associated mutations in calcium/sodium channels and pathogenic changes in nonmutant potassium channels.
Blotting, Western
;
Calcium
;
Calcium Channels
;
Channelopathies
;
Cytosol
;
Humans
;
Hypokalemia
;
Hypokalemic Periodic Paralysis*
;
Large-Conductance Calcium-Activated Potassium Channels
;
Membranes
;
Muscle Weakness
;
Muscle, Skeletal
;
Paralysis
;
Polymerase Chain Reaction
;
Potassium
;
Potassium Channels
;
Potassium Channels, Calcium-Activated*
;
Reverse Transcription
;
RNA, Messenger
;
Sodium Channels
10.Subcutaneous Panniculitis-like T cell Lymphoma with Hemophagocytic Syndrome.
So Young KIM ; Sook Hyun BANG ; Myung Hwa KIM ; Min Sun CHO ; Hae Young CHOI ; Ki Bum MYUNG
Korean Journal of Dermatology 2005;43(4):507-511
Subcutaneous pnniculitis-like T cell lymphoma (SPTCL) is a rare subtype of cutaneous T cell lymphoma which clinically and histopathologically mimics benign panniculitis. It presents as tender erythematous, subcutaneous nodules or plaques on the extremities and trunk, and displays systemic symptoms such as weight loss, fever, chills, fatigue or myaligia. The association of hemophagocytic syndrome (HPS) portends a poor prognosis. We report a case of SPTCL that occurred in a 20-month-old girl. She presented with multiple erythematous subcutaneous nodules on the face, right thigh, buttocks and trunk, plus fever and vomiting. Histopathological examination of the subcutaneous nodules revealed a dense infiltration of atypical T-lymphoid cells in the subcutaneous fat layer, with rimming of fat cells, numerous karyorrhetic bodies and histiocytes, phagocytosed apoptotic cells and Bean bag cells In spite of combination chemotherapy, she died of disseminated intravascular coagulation due to HPS.
Adipocytes
;
Buttocks
;
Chills
;
Disseminated Intravascular Coagulation
;
Drug Therapy, Combination
;
Extremities
;
Fatigue
;
Female
;
Fever
;
Histiocytes
;
Humans
;
Infant
;
Lymphohistiocytosis, Hemophagocytic*
;
Lymphoma, T-Cell*
;
Lymphoma, T-Cell, Cutaneous
;
Panniculitis
;
Prognosis
;
Subcutaneous Fat
;
Thigh
;
Vomiting
;
Weight Loss