1.The analysis of prognostic factors in endometrial cancer managed with surgical staging.
Jung Hye YUN ; Hyun Suk RHO ; Jin Woo SIN ; Jong Min LEE ; Chan Yong PARK
Korean Journal of Gynecologic Oncology 2006;17(2):129-133
OBJECTIVE: To determine pathologic variables associated with overall survival and disease free survival of patients with endometrial cancer. METHODS: Survival of 81 endometrial cancer patients treated with primary surgery between January 1997 and December 2003 at our center was compared about various histopathologic variables. All patients underwent complete surgical staging including pelvic +/- paraaortic lymph node dissection. Survival analyses were performed by the Kaplan-Meier curves and the log-rank test. Independent prognostic factors were determined by Cox's proportional hazards model using likelihood-ratio statistics based on the conditional parameter estimate (Conditional). RESULTS: With regard to disease free survival, univariate analysis revealed no significant differences in subgroups according to age category, grade and adjuvant radiotherapy. However, significant differences in disease free survival were found between stage I+II and stage III, and between endometrioid type and the others type. Among these significant subgroups, the Cox-proportional hazards model showed that stage was the only independent prognostic factor. There were no significant differences in the overall survival of patients in subgroups according to age category and adjuvant radiotherapy. But, significant differences in overall survival were found in subgroups according to stage, histology and grade. Multivariate analysis revealed that stage was the only independent significant adverse prognostic effect. CONCLUSION: Our results showed that only stage was an independent prognostic factor of disease free survival and overall survival in endometrial cancer patients.
Disease-Free Survival
;
Endometrial Neoplasms*
;
Female
;
Humans
;
Lymph Node Excision
;
Multivariate Analysis
;
Proportional Hazards Models
;
Radiotherapy, Adjuvant
2.A Case of Diagnosis and Management of Noncommunicating Rudimentary Horn Pregnancy with the Use of Laparoscopy.
Woo Suk RA ; Ki Hwan KIM ; Chang Up SON ; Min CHOUNG ; Jeong Hoon RHO ; In Tak HWANG ; Joon Suk PARK
Korean Journal of Perinatology 2007;18(4):415-418
A non-communicating rudimentary uterine horn is a rare Mllerian duct anomaly. We experienced a case of unruptured rudimentary uterine horn pregnancy. The patient was diagnosed by laparoscopy and removed by laparoscopic resection of the pregnant rudimentary uterine horn was performed. We report our case with brief review of literatures.
Animals
;
Diagnosis*
;
Horns*
;
Humans
;
Laparoscopy*
;
Pregnancy*
3.Laparoscopic assisted vaginal hysterectomy for large uterus; the comparison of conventional LAVH with LH.
Woo Suk NA ; Ki Hwan KIM ; Byung Kwan LEE ; Jeong Hoon RHO ; Chang Up SON ; Min CHOUNG ; Yoon Seok YANG ; Joon Suk PARK
Korean Journal of Gynecologic Oncology 2007;18(3):227-234
OBJECTIVE: To compare clinical results of laparoscopic assisted vaginal hysterectomy for uteri weighing 500 g or more with less than 500 g. And we compared clinical results between laparoscopic coagulation of uterine vessel (LH) and conventional LAVH. METHODS: We reviewed medical records of 296 patient who underwent LAVH from February 2004 to May 2006. They were divided into two groups, uteri weighing greater than 500 g and less than 500 g. And each group was divided into two groups, LH and conventional LAVH. Each groups were compared by operative time, hemoglobin change, complication, transfusion and hospital days. RESULTS: Operation time ,hemoglobin change on the 1st postoperative day and transfusion were significant greater in the uteri > or =500 g group than in the <500 g. However, there was no significant difference in hospital days, hemoglobin change on the 4th postoperative day and complication. In the <500 g group, LH group was lower than conventional LAVH group in operative time, hemoglobin change on the 1st and 4th postoperative day. In the > or =500 g group, there was no signicant difference in hospital days, operative time, hemoglobin change on the 1st postoperative day. However, hemoglobin change was smaller in the LH group than conventional LAVH group on the 4th postoperative day. CONCLUSION: This study demonstrates that despite the increased operating time and blood loss, LAVH can be safely performed for large uterus. However, surgeons need to be aware of high risk of blood transfusion. Modification of surgical method can decrease operating time and blood loss in LAVH.
Blood Transfusion
;
Female
;
Humans
;
Hysterectomy
;
Hysterectomy, Vaginal*
;
Medical Records
;
Operative Time
;
Uterus*
4.Prognostic factors of cervical cancer stage IB2 treated surgically.
Hea Young OH ; Sung Wook JUN ; Hyun Suk RHO ; Kwang Beom LEE ; Jin Woo SHIN ; Jong Min LEE ; Chan Yong PARK
Korean Journal of Obstetrics and Gynecology 2006;49(3):572-579
OBJECTIVE: This study was performed to identify pathologic and clinical risk factors that predicted survival in cervical cancer stage IB2 patients treated surgically. METHODS: The records of 52 patients with cervical cancer IB2 who underwent radical hysterectomy with pelvic lymph node dissection from 1997 to 2003 were reviewed retrospectively. Clinical and pathologic variables included age, tumor size (TS), histologic type, involvement of resection margin, parametrium invasion, lymph node metastasis (LN), lymph-vascular space invasion, depth of invasion, treatment modality and adjuvant radiation therapy (RTx). Survival analyses were performed by the Kaplan-Meier curves and the log-rank test. Independent prognostic factors were determined by Cox's proportional hazards model. RESULTS: In the present study, median follow up was 46.5 months. With regard to the 2-year disease free survival rate and the 5-year survival rate, univariate analysis revealed no significant differences in subgroups according to age, histologic type, resection margin, parametrium, lymph-vascular space invasion, depth of invasion and treatment modality. Tumor size (p=0.0024), lymph node metastasis (p=0.0007) and radiation therapy (p=0.0398) significantly affected the 2-year disease free survival rate in univariate analysis. They (TS: p=0.0001, LN: p=0.0023, RTx: p=0.0428) also significantly affected 5-year survival rate in univariate analysis. Tumor size (RR 35.87, CI 2.94-438.26, p=0.01) and lymph node metastasis (RR 16.6, CI 1.36-202.05, p=0.03) affected 5-year survival rate in multivariate analysis. CONCLUSION: In patients with cervical cancer stage IB2 who underwent operation regardless adjuvant radiation therapy, the important independent prognostic factors were tumor size and LN metastasis.
Disease-Free Survival
;
Follow-Up Studies
;
Humans
;
Hysterectomy
;
Lymph Node Excision
;
Lymph Nodes
;
Multivariate Analysis
;
Neoplasm Metastasis
;
Proportional Hazards Models
;
Retrospective Studies
;
Risk Factors
;
Survival Rate
;
Uterine Cervical Neoplasms*
5.A Validation Study of the Korean-version of Symmetry, Ordering and Arranging Questionnaire.
Kyung Ryeol CHA ; Joon Suk LIM ; Junyoung PARK ; Su young LEE ; Kwanguk KIM ; Dae Young RHO ; Se Joo KIM ; Min Seong KOO ; Chan Hyung KIM
Journal of Korean Neuropsychiatric Association 2008;47(3):263-268
OBJECTIVES: The Symmetry, Ordering and Arranging Questionnaire (SOAQ) has been reported as a valid tool for the assessment of symmetry, ordering and arranging compulsive behaviors of patients with obsessive compulsive disorder. It was introduced by Radomsky and Rachman in 2004. The aim of this study was to assess the reliability, validity and psychometric properties of the Korean-version of the SOAQ (K-SOAQ). METHODS: Two hundreds twenty eight under-graduate college students were enrolled in this study. They were assessed with K-SOAQ, Obsessive-Compulsive Inventory-Revised (OCI-R), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI). Statistical analysis was done using calculation of Cronbach's alpha, Spearman Correlation Coefficient and Principal Components Analysis. RESULTS: There were no significant differences in sex, education, and total scores of BDI and BAI. The Cronbach's alpha coefficient of K-SOAQ was high, Cronbach's alpha=0.96. There was strong evidence for a one-factor solution, accounting for 60.3% of the variance. Convergent validity was examined through correlations between the SOAQ and the OCI-R (r=0.61). Divergent validity was examined through correlations between the SOAQ and two self report measures; BDI (r=0.12) and BAI (r=0.19). CONCLUSION: The K-SOAQ showed good reliability and validity for the assessment of severity of compulsive characteristics regarding symmetry, ordering and arranging. The K-SOAQ is a useful instrument for assessing compulsive symptoms related with symmetry, ordering and arranging in Korea.
Accounting
;
Anxiety
;
Compulsive Behavior
;
Depression
;
Humans
;
Korea
;
Obsessive-Compulsive Disorder
;
Psychometrics
;
Surveys and Questionnaires
;
Reproducibility of Results
;
Self Report
6.Transcatheter Arterial Embolization for Control of Hemoptysis in Pulmonary Tuberculosis: Analysis of Prognostic Factors.
Ji Young RHO ; Byung Suk ROH ; Eun A KIM ; Ki Han PARK ; Hyo Sung KWAK ; Young Min HAN ; Seon Kwan JUHNG ; Eun Taik JEONG ; Jong Jin WON
Journal of the Korean Radiological Society 1998;39(3):511-516
PURPOSE: To evaluate the effectiveness of transcatheter arterial embolization(TAE) and the relationshipbetween therapeutic effect and prognostic factors after this procedure. MATERIALS AND METHODS: Fifty-fivepatients with hemoptysis caused by pulmonary tuberculosis(TB) underwent TAE. We reviewed medical records of thehistory and activity of pulmonary TB, and the extent of treatment, and assessed plain chest PA for the extent oflesions ; we also evaluated the angiographic findings of embolized arteries, and embolic agents. The initialsuccess rate, as shown by immediate response, and recurrence during follow-up, were then observed. Using theChi-square test, differences in these findings were analysed. RESULTS: Immediate control of hemoptysis wasachieved in 46 of 55 patients(84%); 24 of 46(52.2%), experienced recurrence. Initial failure and partial responserates were higher in patients with active pulmonary TB(p<0.05) than in those in whom the condition was inactive.The recurrence rate was higher among those who had had pulmonary TB for between one and ten years (p<0.05). Therewas, however, no significant correlation between therapeutic effect and the extent of anti-TB treatment, theextent of lesions seen on plain chest PA, angiographic findings, embolized arteries, and embolic agents. CONCLUSION: The initial success rate of TAE was 84% and the recurrence rate was as high as 52.2%. Both activityand duration of pulmonary TB were prognostic factors in immediate response and recurrence.
Arteries
;
Bronchial Arteries
;
Follow-Up Studies
;
Hemoptysis*
;
Humans
;
Medical Records
;
Recurrence
;
Thorax
;
Tuberculosis, Pulmonary*
7.Preschool Vision Screening in Korea: Preliminary Study.
Young Suk YU ; Sang Min KIM ; Jung Youn KWON ; Bong Cheal KIM ; Sook OH ; Young Bae RHO ; Won Real LEE
Journal of the Korean Ophthalmological Society 1991;32(12):1092-1096
Vision Screening of 1211 preschool children at 6-year-old was done by the visual acuty test, the cover test, and the stereoacuity test primarily. Secondarily, the corrected visual acuity, the refractive state. the amount of ocular deviation, and the cause of amblyopia were evaluated if the monocular acuity was 0.6 or less, or the difference of two or more lines on the Han's chart between right and left eye with the best optical correction was present, or the strabismus was detected on the primary screening. One hundred and thirty-eight children(11.4%) were abnormal on the primary screening. Seventy-nine children showed myopia. 46 hyperopia, and 3 alisometropia with the cycloplegic refraction, and 79 children also had astigmatism. Twelve children showed strabismus with the cover test. Among those, 8 belonged to exotropia and 4 to esotropia. Six children showed amblyopia and the causes of amblyopia were astigmatism, exotropla, and anisometropia. Among these 6 amblyops, 3 showed abnormal findings with the cover test and 2 showed stereocuity over 1200 seconds of arc. Therfore, among these three tests as primary vision screening, the cover test and the stereoacuity test to be inadequate to detect the amblyopia.
Amblyopia
;
Anisometropia
;
Astigmatism
;
Child
;
Child, Preschool
;
Esotropia
;
Exotropia
;
Humans
;
Hyperopia
;
Korea*
;
Mass Screening
;
Myopia
;
Strabismus
;
Vision Screening*
;
Visual Acuity
8.A Case of Placenta Increta in the Uterine Sacculation which was Treated with Conservative Methods.
Min CHOUNG ; Jeong Hoon RHO ; Chang Up SON ; Woo Suk NA ; Byung Kwan LEE ; Young Rae SONG ; Ji Hoon RYU ; In Taek HWANG ; Ki Hwan KIM
Korean Journal of Perinatology 2007;18(3):277-285
Uterine sacculation is a very rare complication associated with pregnancy in which a part of the uterine wall balloons, and it is difficult to diagnose because it is usually asymptomatic. It frequently contains the placenta and sometimes may be involved with the trapped placenta after delivery due to its structural characteristic. It is impossible to remove the retained placenta in the sac by using usual methods such as manual delivery or curettage so most of patients with it end up with having a laparotomy. Especially, if the placenta in it is accompanied by abnormal adherence of the placenta or serious hemorrhage, hysterectomy should be considered. Currently several conservative methods for the retained placenta including selective uterine artery embolization and administration of methotrexate have been introduced and these may be tried to treat the retained placenta in the uterine sacculation for avoiding operation and preserving future reproductive potential in selective cases. We experienced a case of placenta increta in the uterine sacculation that was diagnosed first during cesarian section and was treated with selective uterine artery embolization followed by methotrexate administration. This case is reported with a brief review of the literatures.
Curettage
;
Hemorrhage
;
Humans
;
Hysterectomy
;
Laparotomy
;
Methotrexate
;
Placenta Accreta*
;
Placenta*
;
Placenta, Retained
;
Pregnancy
;
Uterine Artery Embolization
9.A Case of Placenta Increta in the Uterine Sacculation which was Treated with Conservative Methods.
Min CHOUNG ; Jeong Hoon RHO ; Chang Up SON ; Woo Suk NA ; Byung Kwan LEE ; Young Rae SONG ; Ji Hoon RYU ; In Taek HWANG ; Ki Hwan KIM
Korean Journal of Perinatology 2007;18(3):277-285
Uterine sacculation is a very rare complication associated with pregnancy in which a part of the uterine wall balloons, and it is difficult to diagnose because it is usually asymptomatic. It frequently contains the placenta and sometimes may be involved with the trapped placenta after delivery due to its structural characteristic. It is impossible to remove the retained placenta in the sac by using usual methods such as manual delivery or curettage so most of patients with it end up with having a laparotomy. Especially, if the placenta in it is accompanied by abnormal adherence of the placenta or serious hemorrhage, hysterectomy should be considered. Currently several conservative methods for the retained placenta including selective uterine artery embolization and administration of methotrexate have been introduced and these may be tried to treat the retained placenta in the uterine sacculation for avoiding operation and preserving future reproductive potential in selective cases. We experienced a case of placenta increta in the uterine sacculation that was diagnosed first during cesarian section and was treated with selective uterine artery embolization followed by methotrexate administration. This case is reported with a brief review of the literatures.
Curettage
;
Hemorrhage
;
Humans
;
Hysterectomy
;
Laparotomy
;
Methotrexate
;
Placenta Accreta*
;
Placenta*
;
Placenta, Retained
;
Pregnancy
;
Uterine Artery Embolization
10.Clinical Characteristics of Thyroid Micropapillary Carcinoma.
Sang Hyuk LEE ; Sung Min JIN ; Young Soo RHO ; Jin Hwan KIM ; Seung Suk LEE ; Hyun Jin CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 2007;50(7):627-631
BACKGROUND AND OBJECTIVES: Papillary microcarcinoma of the thyroid gland (PMC) is defined as a papillary thyroid cancer (PTC) measuring less than 1 cm in its diameter. PMC is frequently diagnosed today, mainly as a result of the wide use of neck ultrasonography and fine needle aspiration biopsy. Despite the overall excellent prognosis for patients with PMC, the extent of thyroid resection and the necessity of lymph node dissection have become the issues of controversy. The rising incidence of the PMC among PTC necessitates the identification of prognostic factors and standardization of treatment protocols. Therefore, to evaluate the characteristics of PMC, we reviewed our experiences. SUBJECTS AND METHOD: Between 2000 and 2005, 265 patients underwent thyroid surgery and 194 patients showed PTC. Of these patients, 53 patients (27.3%) had PMC (9 male, 44 female, mean age 50.1 years). The data from these patients were retrospectively analyzed. RESULTS: The mean tumor size was 7.19 mm. The most frequently presenting symptom was thyroid mass only (77%) and the combined thyroid diseases were found in 35 patients (66%). Twelve patients (27.9%) had multifocal microcarcinomas and in 11 patients (20.8%) had extrathyroidal invasion. Lymph node metastasis was found in 18 patients (33.9%). Lymph node metastasis was significantly associated with the presence of extrathyroidal invasion (p=0.031), lymph node metastasis (p=0.008) and extrathyroidal invasion are more frequently observed in PMCs over 5 mm in size. CONCLUSION: These clinical characteristics may be considered as prognostic factors of the PMC. So the treatment modalities should be chosen taking into consideration of the various clinical factors.
Biopsy
;
Biopsy, Fine-Needle
;
Clinical Protocols
;
Female
;
Humans
;
Incidence
;
Lymph Node Excision
;
Lymph Nodes
;
Male
;
Neck
;
Neoplasm Metastasis
;
Prognosis
;
Retrospective Studies
;
Thyroid Diseases
;
Thyroid Gland*
;
Thyroid Neoplasms
;
Ultrasonography