1.Prenatal 3D-ultrasound diagnosis of Otocephaly and Holoprosencephaly-Cyclopia.
Min Jeoung KIM ; Hyo Jin KIM ; Min Jeoung HA ; Jeoung Min MOON ; Eun Young JI ; In Yang PARK ; Soo Young HUR ; Gui Sera LEE ; Joung Chul SHIN ; Sa Jin KIM
Korean Journal of Obstetrics and Gynecology 2005;48(10):2422-2427
Otocephaly is a rare malformations comprising hypoplasia or absence of the mandible (agnathia), ventromedial displacement and often fusion of external ears (synotia or otocephaly), and hypoplasia of the oral cavity (microstomia) and tongue (hypoglassia). This developmental complex represents a malformation of the first and second branchial arches and occurs sometimes with holoprosencephaly. We present the ultrasound detection of otocephaly and holoprosencephaly with cyclopia in a fetus of 27 gestational weeks 6 days. The use of three-dimensional (3-D) ultrasound made additional diagnostic ultrasound tomograms possible, and the volume reconstructions improved the imaging and the understanding of the condition.
Branchial Region
;
Diagnosis*
;
Ear, External
;
Fetus
;
Holoprosencephaly
;
Mandible
;
Mouth
;
Tongue
;
Ultrasonography
2.Complete Remission from C1q Nephropathy with Disappearance of C1q Deposition after Steroid Therapy.
Hyaejin YUN ; Sung Min JEOUNG ; Hyun Soon LEE ; Byoung Soo CHO
Korean Journal of Medicine 2016;91(3):311-315
C1q nephropathy is a rare glomerular disease, defined by characteristic mesangial C1q immune deposition seen in immunofluorescence microscopy with no serological evidence of systemic lupus erythematosus. C1q nephropathy can be diagnosed with a subsequent biopsy, as with IgA nephropathy. There are some cases with an initial diagnosis of hematuria and proteinuria with minimal disease changes, focal segmental glomerulonephritis, and mesangial proliferative glomerulonephritis, but lacking C1q nephropathy, in which C1q deposition on immunofluorescence subsequently develops. We report a case that was diagnosed as diffuse mesangial proliferative glomerulonephritis, but a subsequent biopsy showed C1q nephropathy, with C1q deposition in both immunohistochemistry and electron microscopy (EM). We treated the C1q nephropathy with methylprednisolone and confirmed the disappearance of C1q depositions by both immunohistochemistry and EM in a follow-up biopsy.
Biopsy
;
Complement C1q
;
Diagnosis
;
Fluorescent Antibody Technique
;
Follow-Up Studies
;
Glomerulonephritis
;
Glomerulonephritis, IGA
;
Hematuria
;
Immunohistochemistry
;
Lupus Erythematosus, Systemic
;
Methylprednisolone
;
Microscopy, Electron
;
Microscopy, Fluorescence
;
Proteinuria
3.A Standardization Study of Korean DFS (Delivery Fear Scale) in fear of childbirth.
Min Jeoung KIM ; Jae Woo PARK ; Min Jeoung HA ; Hyun Young AHN ; In Yang PARK ; Soo Young HUR ; Gui Sera LEE ; Joung Chul SHIN ; Dae Jin KIM ; Sa Jin KIM
Korean Journal of Obstetrics and Gynecology 2006;49(1):70-75
OBJECTIVE: The study shows that the DFS is a questionnaire that almost effortlessly can be completed within 60-90 seconds during any moment of labor and delivery. The aim of the present study was to test the validity and reliability of the DFS, to identify its factor structure in Korea. METHODS: Review of the medical records from the department of obstetrics and gynecology from January to April 2005, a confirmed 51 patients with the diagnosis of singleton pregnancy without medical or obstetrical complications, being in 37-42 weeks. 22 primiparous and 29 multiparous women answered the Delivery Fear Scale (DFS) once during active labor, and the STAI (State-Trait Anxiety Inventory) after delivery. Reliability test to calculate Chronbach alpha and validity test to measure correlation between DFS and STAI was done. Then factor analysis was applied with the method of principal component analysis and varimax rotation. RESULTS: Korean version of DFS proved to be a reliable and valid scale statistically: Cronbach's alpha was 0.7182 in study. CONCLUSION: Women's psychological experiences during the actual process of labor and delivery are essential part of obstetrical care. Nevertheless, studies examining psychological variables concerning childbirth, are mostly performed before or after labor. The DFS measures fear during labor and delivery in an effortless and fast away. The development of the Korean version of DFS which is reliable and valid, and consists of three sub-factors may facilitate future research in the field.
Anxiety
;
Diagnosis
;
Female
;
Gynecology
;
Humans
;
Korea
;
Medical Records
;
Obstetrics
;
Parturition*
;
Pregnancy
;
Principal Component Analysis
;
Surveys and Questionnaire
;
Reproducibility of Results
4.Electrocardiographic and Echocardiographic Characterisitics of Wolff-Parkinson-White Syndrome in Preschool Children.
Jeoung Min CHU ; Hyun Sup SIM ; Soo Chul CHO ; Chan Uhng JOO
Journal of the Korean Pediatric Society 2002;45(9):1097-1105
PURPOSE: This study was conducted to estabilish the prevalence, clinical features and relationship between ECG findings and echocardiographic findings of Wolff-Parkinsion-White(WPW) syndrome in asymptomatic preschool children. METHODS: An electrocardiographic screening study was performed on 77,824 preschool children in Jeonbuk province from April, 1999 to August, 2001. Patients with WPW syndrome underwent echocardiographic study. RESULTS: Twenty three patients with WPW syndrome were discovered by electrocardiographic screening of preschool children. The prevalence rate was 2.9 per 10,000 preschool children and there was no significant sexual difference. Two patients had a history of symptoms related to tachyarrythmia. According to the ECG classification of Rosenbaum et al., five patients were type A and 18 were type B. Utilizing the criteria of Gallagher et al, right anterior, 12 patients; right anteiror paraseptal, four patients; left anteiror, three patients. Nineteen of 23 patients underwent echocardiographic study. Four of five patients with type A WPW syndrome had abnormal early systolic anterior motion of left ventricular posterior wall. Twelve of 14 patients with type B had abnormal interventricular septal motion characterized by early sytolic posterior motion immediately after inscription of the delta wave. CONCLUSION: The prevalence rate of preschool children in Jeonbuk province was 2.9/10,000. By the classification according to the electrocardiographic findings, the accessory pathway location was dominant right side than left side. In the echocardiographic study, type A WPW syndrome showed abnormal left ventricular posterior wall motion and type B WPW showed abnormal interventricular septal motion.
Child, Preschool*
;
Classification
;
Echocardiography*
;
Electrocardiography*
;
Humans
;
Jeollabuk-do
;
Mass Screening
;
Prevalence
;
Wolff-Parkinson-White Syndrome*
5.Alteration of insulin resistance and serum adiponectin levels after one year follow-up of obese children and adolescents.
Min Jee JEOUNG ; Jung Yeon SHIN ; Soo Young KIM ; Jung Hwa LEE ; Kee Hyoung LEE ; Joo Won LEE
Korean Journal of Pediatrics 2007;50(8):767-773
PURPOSE: Obesity has become a pandemic and especially the prevalence of childhood obesity has increased remarkably over the past years. Childhood obesity is often accompanied by the expected morbidities such as hyperlipidemia, fatty liver and glucose intolerance. We evaluated the pattern of alteration in the body mass index (BMI), serum adiponectin concentration, insulin resistance (HOMA-IR), and complication rates after one year follow-up. METHODS: Forty two obese children (age: 8-15 years, 95th percentile of BMI for age and sex) were examined twice annually on June, 2004 and July, 2005. The body mass index (BMI) and sexual maturity rating (SMR) were determined annually by the same examiner and serum fasting glucose, liver enzyme, lipid profiles, adiponectin, insulin and HOMA-IR were measured and annual results were compared. Upper abdominal sonography was performed to detect fatty liver. RESULTS: BMI (25.3+/-2.9 kg/m2 vs. 26.0+/-2.9 kg/m2) and HOMA-IR (3.6+/-1.8 vs. 4.7+/-1.9) have increased significantly after one-year follow-up. The serum adiponectin concentration (17.2+/-5.2 g/mL vs. 12.6+/-5.2 g/mL) has decreased after one year. The prevalence of hyperlipidemia and fatty liver were not changed significantly but that of hyperinsulinemia increased after one-year. HOMA-IR showed a positive correlation with BMI and SMR, but was negatively correlated with serum adiponectin concentration. CONCLUSION: Obese children in our study showed significant increment of insulin resistance during one year. These results suggest that well-organized and continuous obesity control is required especially for obese adolescent to prevent complication of obesity.
Adiponectin*
;
Adolescent*
;
Body Mass Index
;
Child*
;
Fasting
;
Fatty Liver
;
Follow-Up Studies*
;
Glucose
;
Glucose Intolerance
;
Humans
;
Hyperinsulinism
;
Hyperlipidemias
;
Insulin Resistance*
;
Insulin*
;
Liver
;
Obesity
;
Pandemics
;
Pediatric Obesity
;
Prevalence
6.The Characteristics of REM Sleep-Dependent Obstructive Sleep Apnea and NREM Sleep-Dependent Obstructive Sleep Apnea.
Min Cheol SEO ; Jae Won CHOI ; Eun Jeoung JOO ; Kyu Young LEE ; Soo Young BHANG ; Eui Joong KIM
Sleep Medicine and Psychophysiology 2017;24(2):106-117
OBJECTIVES: Obstructive sleep apnea (OSA) is a sleep-related breathing disorder that is characterized by repetitive collapse or partial collapse of the upper airway during sleep in spite of ongoing effort to breathe. It is believed that OSA is usually worsened in REM sleep, because muscle tone is suppressed during REM sleep. However, many cases showed a higher apnea-hypopnea index (AHI) during NREM sleep than during REM sleep. We aimed here to determine the characteristics of REM sleep-dependent OSA (REM-OSA) and NREM sleep-dependent OSA (NREM-OSA). METHODS: Five hundred sixty polysomnographically confirmed adult OSA subjects were studied retrospectively. All patients were classified into 3 groups based on the ratio between REM-AHI and NREM-AHI. REM-OSA was defined as REM-AHI/NREM-AHI > 2, NREM-OSA as NREM-AHI/REM-AHI > 2, and the rest as sleep stage-independent OSA (IND-OSA). In addition to polysomnography, questionnaires related to subjective sleep quality, daytime sleepiness, and emotion were completed. Chi-square test, ANOVA, and ANCOVA were performed. RESULTS: There was no age difference among subgroups. The REM-OSA group was comprised of large proportions of mild OSA and female OSA patients. These patients experienced poor sleep and more negative emotions than other two groups. The AHI and oxygen desaturation index (ODI) were lowest in REM-OSA. Sleep efficiency and N3 percentage of REM-OSA were higher than in NREM-OSA. The percentage of patients who slept in a supine position was higher in REM-OSA than other subgroups. IND-OSA showed higher BMI and larger neck circumference and abdominal circumference than REM-OSA. The patients with IND-OSA experienced more sleepiness than the other groups. AHI and ODI were highest in IND-OSA. NREM-OSA presented the shortest total sleep time and the lowest sleep efficiency. NREM-OSA showed shorter sleep latency and REM latency and higher percentage of N1 than those of REM-OSA and the highest proportion of those who slept in a lateral position than other subgroups. NREM-OSA revealed the highest composite score on the Horne and Östberg questionnaire. With increased AHI severity, the numbers of apnea and hypopnea events during REM sleep decreased, and the numbers of apnea and hypopnea events during NREM sleep increased. The results of ANCOVA after controlling age, sex, BMI, NC, AC, and AHI showed the lowest sleep efficiency, the highest AHI in the supine position, and the highest percentage of waking after sleep onset in NREM-OSA. CONCLUSION: REM-OSA was associated with the mild form of OSA, female sex, and negative emotions. IND-OSA was associated with the severe form of OSA. NREM-OSA was most closely related to position and showed the lowest sleep efficiency. Sleep stage-dependent characteristics could provide better understanding of OSA.
Adult
;
Animals
;
Apnea
;
Female
;
Horns
;
Humans
;
Neck
;
Oxygen
;
Polysomnography
;
Respiration
;
Retrospective Studies
;
Sleep Apnea, Obstructive*
;
Sleep, REM
;
Supine Position
7.Identification of epidural space using loss of resistance technique with the combination of liquid and air: a clinical feasibility study.
Min soo KIM ; Sang Hyun LEE ; Tae Yoon JEOUNG ; Seong Sik KANG
Anesthesia and Pain Medicine 2011;6(3):212-215
BACKGROUND: The loss of resistance technique is the most popular method for identifying the epidural space. Air or liquid is a commonly used medium for this technique. These two media have certain advantages and disadvantages. A liquid filled pressure line connected to an air syringe might have advantages of both air and liquid while preventing the drawbacks of each medium. METHODS: Twenty-five consecutive patients were scheduled to receive an epidural anesthesia for surgery and selected for study. A lidocaine filled pressure line connected to an air syringe allowed for sequential injection of lidocaine and air. The time spent on the procedure, amount of air injected into the epidural space, inadvertent puncture of the dura mater, and rate of anesthetic failure were recorded. RESULTS: The procedure took less than 2 minutes in 22 cases. The average amount of air lost from the syringe during the loss of resistance test was 0.98 +/- 0.23 ml in 22 patients. Volume of the 3-way connected pressure line was 0.95 ml. Therefore, the air volume injected into the epidural space was minimal. In the other 3 cases where previous spinal disease existed, multiple epidural approaches were needed and the procedure took relatively longer with larger injection volumes. There were no complications. CONCLUSIONS: This technique minimized injection of the air into the epidural space during identification but simultaneously, it does not disturb the feel of air compressibility in the syringe.
Anesthesia, Epidural
;
Dura Mater
;
Epidural Space
;
Feasibility Studies
;
Humans
;
Lidocaine
;
Punctures
;
Spinal Diseases
;
Syringes
8.A clinical review of emphysematous pyelonephritis.
Gang Wook YI ; Jeong Ho LEE ; Min Soo JEOUNG ; Sunn Kgoo RHEE ; Seoung Hun SHIN ; Young Tai SHIN ; Young Kun KIM ; Chong Koo SUL ; Yool Ro YOON
Korean Journal of Nephrology 1991;10(4):526-533
No abstract available.
Pyelonephritis*
9.Cytologic Featrues of Pituitary Adenoma: A Case Report by Fine Needle Aspiration.
Minsun CHO ; Mi Jung KIM ; Sung Sook KIM ; Hea Soo KIM ; Sung Min JEOUNG ; Sung Hak KIM
Korean Journal of Cytopathology 1994;5(2):184-188
Therapeutic management of brain tumors is based on accurate knowledge of their size, location and histologic type. Stereotaxic cytology under CT guidance has been applied to the investigation of brain tumors, especially in the sellar turcica, third ventricle, and pineal regions. In the present case, the tumor protruded into the nasal cavity, so we were able to get cytologic material via fine needle aspiration.
Biopsy, Fine-Needle*
;
Brain Neoplasms
;
Nasal Cavity
;
Pituitary Neoplasms*
;
Third Ventricle
10.The efficacy of sonographic morphology indexing and serum CA-125 for preoperative differentiation of malignant from benign ovarian tumors in patients after operation with ovarian tumors.
Hyo Young JEOUNG ; Han Song CHOI ; Yo Sup LIM ; Min Young LEE ; Soo A KIM ; Sei Jun HAN ; Tae Gyu AHN ; Sang Joon CHOI
Journal of Gynecologic Oncology 2008;19(4):229-235
OBJECTIVE: To evaluate the value of sonographic morphology indexing (MI) system and serum CA-125 levels in the assessment of the malignancy risk in patients with ovarian tumors. METHODS: From September 2000 to July 2006, 202 patients who underwent surgery for ovarian tumors were reviewed retrospectively. In all patients, the MI score and serum CA-125 level were measured preoperatively. The association of the final pathologic diagnosis with the MI score and serum CA-125 level were examined. RESULTS: There were 26 malignant tumors out of 141 ovarian tumors with a MI > or =5 (18%). With a cut-off value of 5, the sensitivity, specificity, PPV, and NPV of MI scores were 0.743, 0.293, 0.181, and 0.845, respectively. There were 22 malignant tumors out of 54 ovarian tumors with serum CA-125 >30 u/ml (41%). With a cut-off value of 30 u/ml, the sensitivity, specificity, PPV, and NPV of serum CA-125 level were 0.667, 0.808, 0.407, and NPV 0.925, respectively. On ROC curve, the optimal cut-off value of MI score was 6.5-7.5 and that of serum CA-125 level was 25.6-28.5 u/ml. With a cut-off value of 7, the sensitivity and 1-specificity of MI score were 0.875-0.917 and 0.023-0.203, respectively. After the exclusion of teratoma cases, the sensitivity and 1-specificity of MI score were 0.875-0.917 and 0.046-0.138, respectively. With a cut-off value of 25.6-28.5 u/ml, the sensitivity and 1-specificity of serum CA-125 level were 0.958 and 0.203-0.215, respectively. CONCLUSION: The sonographic MI system is an accurate and simple method to differentiate a malignant tumor from a benign ovarian tumor. The accuracy of the sonographic MI system improved when the serum CA-125 level was considered and ovarian teratomas were excluded.
Abstracting and Indexing as Topic
;
CA-125 Antigen
;
Humans
;
Retrospective Studies
;
ROC Curve
;
Sensitivity and Specificity
;
Teratoma