1.A Case of Dermoid Cyst.
Seok Ho KIM ; Jong Min KIM ; Eil Soo LEE
Korean Journal of Dermatology 1987;25(5):689-691
A 13-year-old male presented a single, elevated, oval, walnut sized, soft mass on the left retroauricular ares which has increased in size since birth, Histopathologic examination revealed a cyst in the subcutaneus area. Cyst wall is lined by normal epiderrnis and cyst cavity contains hairs and keratinous materials.
Adolescent
;
Dermoid Cyst*
;
Hair
;
Humans
;
Juglans
;
Male
;
Parturition
2.Clinical significance of urinary growth hormone measurement in patients with growth hormone deficiency.
Ho Seong KIM ; Duk Hi KIM ; Min Seok CHEON
Journal of the Korean Pediatric Society 1993;36(4):478-484
Urinary growth hormone (GH) excretion was quantitated in 12-hr overnight urine collections obtained from 13 children with complete growth hormone deficiency (CGHD). 6 children with partial growth hormone deficiency (PGHD), 5 children with short stature and normal GH provocation tests (NSC), and 5 normal control children (NC) to investigate whether the measurement of urinary GH can clearly separate the PGHD and CGHD groups from the NSC and NC groups. In addition, the urinary excretion of GH was measured in CGHD after sc injections of 0.1 IU/kg GH three times a week and daily in an attempt to determine the optimal replacement dose. The results were as follows. 1) The 12-hr urinary GH excretion cleary separated the CGHD (1.2+/-1.1 ng/12 hr; range, 0.3-3.1, n=13) and PGHD (3.7+/-2.4 ng/12 hr; range, 0.9-6.8 n=6) groups from the NSC (14.0+/-3.6 ng/12 hr; range, 8.5-18.2 n=5) and NC (12.7+/-5.8 ng/12 hr; range, 6.9-20.8, n=5) groups without any overlap. 2) There were significant difference in 12-hr urinary GH excretion between CGHD and PGHD, but the higher values in CGHD groups overlapped some of the lower values in PGHD group. 3) There were no differencies in 12-hr urinary GH excretion between NC and NSC. 4) A 12-hr urinary GH values less than 6.9 ng/12 hr suggested GH deficiency. 5) The CGHD patients who received o.1 IU/kg GH. sc. daily GH levels within the range of the mean +/-SD in NC. but those who received theree times a week had daily variable urinary GH levels. These results suggest that the measurement of 12-hr nocturnal urinary GH excretion monitering of GH therapy response.
Child
;
Growth Hormone*
;
Humans
;
Urine Specimen Collection
3.Immunohistochemical study on the distribution of hyman papillomavirus(HPV) 16/18 in oral squamous cell carcinomas, leukoplakias and papillomas.
Woo Seok MIN ; Eui Wung LEE ; Jin KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(4):477-487
No abstract available.
Carcinoma, Squamous Cell*
;
Leukoplakia*
;
Papilloma*
4.Hypokalemic Periodic Paralysis.
Seok Min CHOI ; Jong Kyun LEE ; Pyung Kil KIM
Journal of the Korean Pediatric Society 1988;31(11):1499-1501
No abstract available.
Hypokalemic Periodic Paralysis*
5.Clinical Study of Hypophosphatemic Rickets.
Seok Min CHOI ; Duk Hi KIM ; Chin Suck SUH
Journal of the Korean Pediatric Society 1989;32(8):1057-1063
No abstract available.
Rickets, Hypophosphatemic*
6.Clear Cell Hidradenoma: Report of three cases.
Sang Mee SEOK ; Chun Wook PARK ; Jong Min KIM
Annals of Dermatology 1996;8(4):282-286
Clear cell hidradenoma, generally as an eccrine sweat gland origin, is a fairly uncommon tumor and occurs as a slowly growing, usually solitary nodule. The histological patterns vary from one tumor to another and in different parts of the same tumor. We experienced three cases of clear cell hidradenoma which were diagnosed by the histopathologic examination of the tumor mass removed by surgical excision. Clinical and histopathologic features of each case were reviewed and compared.
Acrospiroma*
;
Sweat Glands
7.Photon Defects due to Residual Barium in the Colon Simulating Cold Bone Metastasis in Two Patients with Extraskeletal Cancer.
Seok Tae LIM ; Min Woo KIM ; Myung Hee SOHN
Korean Journal of Nuclear Medicine 2002;36(5):314-316
No abstract available.
Barium*
;
Colon*
;
Humans
;
Neoplasm Metastasis*
8.Two Cases of Neonatal Arrhythmia Observed by Fetal Echocardiography.
Gye Sung KIM ; Seok Min CHOI ; Gyu Hyung LEE
Korean Journal of Perinatology 1999;10(1):71-79
M-mode, pulsed Doppler and Doppler color flow mapping, in addition to two-dimensional echocardiography, have greatly improved imaging of the fetal heart through identification of abnormal cardiac anatomy and rhythm in utero. The early detection of cardiac disturbance in utero permits alteration in obstetric management such as delivery in a high-risk center for optimal neonatal care and/or decision in optimal delivery time. We report two cases of the neonatal arrhy-thmia which were observed by fetal echocardiography. In the first case, female baby showed neonatal arrhythmias including tachycardia and brady-cardia until 3 days after birth, and then turned to bradyarrhythmia due to non-conducted atrial bigeminy. These events lead us to review the fetal echocardiographs of the patient carefully. Premature atrial contractions were observed in her fetal echocardiography. At 2 months after birth, the patient's electrocardiogram showed normal sinus rhythm. Severe neonatal bradycardia of the second case was due to congenital complete heart block, identified clearly by electrocardiogram after birth. This case also showed complete heart block in her fetal echocardiography. After insertion of the temporary pacemaker, cardiomegaly was improved. Both the neonate and the mother had positive anti-SSA/Ro autoantibody. But any other symptoms and signs of neonatal lupus did not appear in the neonate. Patient's mother also did not show any symptoms and signs of systemic lupus erythematosus. Since the prognosis depends upon the cause of bradyarrhythmia in fetus and neonates, differential diagnosis is important in obstetric management and optimal neonatal treatment.
Arrhythmias, Cardiac*
;
Atrial Premature Complexes
;
Bradycardia
;
Cardiomegaly
;
Diagnosis, Differential
;
Echocardiography*
;
Electrocardiography
;
Female
;
Fetal Heart
;
Fetus
;
Heart Block
;
Humans
;
Infant, Newborn
;
Lupus Erythematosus, Systemic
;
Mothers
;
Parturition
;
Prognosis
;
Tachycardia
9.A clinical study of pseudotumor of the orbit.
Yang Gi MIN ; Ic Tae KIM ; Won Seok YU
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(6):1242-1246
No abstract available.
Orbit*
10.The Relationship between Change of Lymphocyte Inositol Monophosphatase mRNA Level by Lithium and Clinical Course in Bipolar Affective Disorder.
Seok Hyeon KIM ; Min Soo LEE ; Jang Han LEE
Journal of the Korean Society of Biological Psychiatry 2001;8(1):96-105
OBJECTIVE: Lithium inhibits the action of inositol monophosphatase(IMPase) in phosphoinositide(PI) signal transduction system at therapeutically relevant concentration. The depletion of inositol by lithium itself cannt explain the lithium's therapeutic effect. However, attention has focused on the abnormality of PI signal transduction system as the pathophysiology of bipolar affective disorder(BPD). We investigated whether IMPase mRNA levels of lymphocytes would be different between BPD patients(n=16) and age, sex-matched normal controls(n=16). We also investigated the change of IMPase mRNA level by lithium during 4 weeks to probe the possibility that IMPase mRNA levels could predict the therapeutic response to lithium and clinical course. METHOD: Relative IMPase mRNA levels in lymphocyte were quantified by reverse transcriptase(RT)-PCR in sixteen drug-free BPD patients and sex, age-matched normal controls. The psychopathology of patients were measured using YMRS(Young Mania Rating Scale) and CGI(Clinical Global Impression). RESULTS: There was no significant difference in IMPase mRNA levels between BPD patients and normal controls. And the IMPase mRNA levels were not significantly changed by 4 week treatment with lithium. However, the basal IMPase mRNA levels were negatively correlated with the changes of CGI after 4 weeks. Furthermore, the patients with relatively high basal IMPase mRNA levels showed much more improvement during 4 weeks. CONCLUSIONS: BPD patients and normal controls were not distinguished by lymphocyte IMPase mRNA level. Although we do not support the hypothesis that lymphocyte IMPase activity would be related with the pathogenesis of BPD and the action of lithium, these data raise the possibility that lymphocyte IMPase mRNA levels could function as a predictor of therapeutic response and clinical course of BPD.
5'-Nucleotidase
;
Bipolar Disorder
;
Humans
;
Inositol*
;
Lithium*
;
Lymphocytes*
;
Mood Disorders*
;
Psychopathology
;
RNA, Messenger*
;
Signal Transduction