Objective To evaluate the clinical curative effect of Liuwei Nengxiao capsules combined with acupoint application for functional constipation. Methods According to the order of treatment, 105 patients with functional constipation were divided into combined treatment group, Liuwei Nengxiao group and acupoint application group with random number table, 35 cases in each group. Combined treatment group was treated with both Liuwei Nengxiao capsules orally taking and Tongbian Fang acupoint application in Shenque. Liuwei Nengxiao group was treated with Liuwei Nengxiao capsules alone, and acupoint application group was treated with Tongbian Fang acupoint application in Shenque alone. The course of treatment lasted for 10 days. The symptom scores were assessed before and after treatment, to evaluate the efficacy. Results The symptom scores of the three groups all decreased after treatment (P<0.05). The total effective rates of combined treatment group, Liuwei Nengxiao group and acupoint application group were 100%(35/35), 94.3% (33/35) and 88.6% (31/35), respectively, and the clinical effect of combined treatment group was better than that of other two groups (P<0.01). Conclusion The clinical effect of Liuwei Nengxiao capsules combined with acupoint application in treating functional constipation is superior to that of separate applications.

Great progresses were made in the genetic study of osteoporosis during the past decade.Genetic variants of endocrine hormones,bone matrix proteins and cytokines involved in bone metabolism were closely associated with bone mineral density,bone quality,bone structure,bone turnover rate or osteoporotic fracture.This paper is a comprehensive review of the most important and representative molecular genetic study in osteoporosis,and the important problems in osteoporosis molecular study.

Objective To investigate the clinical features of children's acute appendicitis in order to reduce the misdiagnose rate.Method Collect and retrospective analyse 77 cases clinical data of children's acute appendicitis from January 2008 to December 2011 in our hospital.Results There are 77 cases abdominal pain,61 cases fever,48 cases vomiting in 77 children,22 cases(28.57％) misdiagnosis or missed diagnosis in total.17 cases with appendix perforation,the perforation rate is 22.07％.49 cases receive surgery,28 cases receive conservative treatment.All are improved and cured and discharged.Conclusions The main clinical features of children's acute appendicitis is abdominal pain,fever and vomiting.When clinical features is not classic,there is higher rate of misdiagnosis and missed diagnosis,especially for infants.Stress that for children with unreasonable abdominal pain and fever,it is necessary to check leukocyte,CRP and type-B ultrasonic,observe the abdominal sign continually,in order to diagnose and treat early.

The paper described the conception and forms of risks for public hospitals financing,proposing the risk avoidance strategy, loss control strategy, and risk transfer strategy against these risks. In addition, it is proposed to take proactive measures to build the financing risk management system for public hospitals, and construct an effective financing risk prewaming mechanism, raise the scientific standard of financial decision-making, and develop a clear-cut economic responsibility system for the hospital leaders during their term, for the purpose of effectively minimizing the risks.

0.05 ), there was no massive haemorrhage, anal incontinence and other serious complications. In the therapeutic group, there were less occurrence of post-operation pain, dropsy in cut edge, remaining wart and anal stricture (P

0. 05),cardiac index decreased from 12. 5% to 13. 3 % during hypotension (P 0. 05 ). It was concluded that PaCO2 can still be followed continuously and noninvasively by monitoring end-tidal CO2 tension during hypotension induced by PGE,

0.05) in both groups. In group B,cardiac output decreased by 13% at 15th min following deliberated hypotension (P0.05). It is suggested that PaCO_2 can be evaluated continuously and noninvasively by monitoring end-tidal CO_2 tension during SNP-induced hypotension.

Pulmonary circulation and gas exchange were observed during and after prostaglandin E_1-indueed hypotention in 9 adult mongrel dogs undergoing procaine balanced anesthesia. Cardiac index decreased from 12.5% to 13% (P0.05) during hypotension but the effective ratios of oxygen increased(P

[Objective]To explore the relationship between Pglycoprotein,survivin expression and chemotherapy outcome.[Method]The expressions of P-glycoprotein,and of survivin were examined by the immunohistochemistry in 38 specimens of preoperation biopsy of osteosarecomas.[Result]The response rate of the P-glycoprotein positive group was lower than that of P-glycoprotein negative group.The response rate of the survivin overexpression group was significant lower than survivin was found to be more valuable in predicting chemotherapy results.[Conclusion]The expressions of P-glycoprotein,and of survivin are clearly associated with osteosarcomas response to chemotherapy in osteosarecoma and survivin is a more valuable parameter.

T),resulting in His to Leu(CAT→CTT) substituted at codon 435(H435L).No mutation was identified in the patient's parents.HT occurred in the patient during following-up.Conclusion H435L mutation in exon 10 of TR? gene leads to resistance to thyroid hormone.Meanwhile,consistent RTH might lead to HT.