Objective To know the efficacy of oral nursing by visible electric toothbrushes among patients with peroral endotracheal intuabtion. Methods Divided 108 trauma patients with peroral endo-tracheal intubation and clear consciousness into the research group and the control group randomly, there were 54 cases in each group. Routine oral nursing cares were used in the control group, while the visible electric toothbrushes was used in the research group. Compared the efficacy of oral nursing between the two groups. Results The incidence rate of mouth odor, plaque index and oral infection in the research group were better than those of in the control group. Conclusions Using visible electric toothbrushes for trau-ma patients with oral endotracheal tube is a kind of effective and feasibility method, which should be devel-oped in the clinical field.

No abstract available.
Adolescent* ; Humans ; Suicide*

To develop optimal shift systems for an improvement of work schedule satisfaction, health and work productivity, the effects of the direction of the rotational work shifting on the circadian rhythm and adaptation of physiological components and work mistakes were investigated in nursing students. Two groups of seven volunteers participated as experimental subjects, apd seven to twenty nursing students participated as a control group. The directions of rotation work shift were as follows CW(clockwise)-shift system rotation in the direction of day shift(3 days), evening shift(3 days), off duty(l day) and night shift(5 days), and CCW (counterclockwise) -shift system rotation in the reverse direction. Urinary Na, K, and Cl levels were measured with ion-selective electrodes. The levels of performance were measured by a questionnaire to determine the number of mistakes in 12 specific items during duty. The disturbance of Na the circadian rhythm was seen on day and night shifts, especially in the CCW-rotation shift system, and the magnitude of the daily variation was greatest in the CCW-rotation system. The daily rhythms of K and Cl shifted to the right on the evening shift, and the rhythms were reversed on the night shift, which suggests that they adapted to the altered shift work. However, the levels of Cl were higher in day and night shift workers, especially in CCW-shift system. In the ease of urine salts, it seems that the students in CW-shift system more easily adapted to the altered shift. The incidence of mistakes during work were more frequent on the CCW shift than in the CW shift. These data indicate that the direction of rotation effects the worker's health and work performance. These results indicate that the CCW rotation of shift work makes it more difficult for the workers to adapt to the shift on a physiological level, and has many more negative effects on the shift workers' health when compared with the CW rotation. Thus, a clockwise rotating shift system seems to be more desirable for the optimal health and performance of nurses.
Appointments and Schedules ; Circadian Rhythm* ; Efficiency ; Humans ; Incidence ; Ion-Selective Electrodes ; Salts ; Students, Nursing ; Volunteers ; Surveys and Questionnaires

Clinical practice is an important link of medical education. The change of medical modes and conditions, the pressure of employment and entrance examination for graduates affect the quality of clinical practice. General hospitals have improved a series of management measures to strengthen and ensure the quality of clinical practice. Furthermore, we shound further explore the new mode of teaching to improve the quality of clinical medicine education.

Objective To observe the effect of potassium sodium dehydroandrographolide succinate for injection (PSDS)combining with smecta enema treatment on children with autumn diarrhea.Methods 102 children patients with autumn diarrhea were selected and divided into the control group,the PSDS group and the combination group with 34 patients in each group.The control group received symptomatic supportive treatment,based upon this,the PSDS group received PSDS,and the combination group adopted PSDS and smecta enema treatment.The treatment effect was compared between the three groups.Results The effect of the PSDS group and the combination group was better than the control group,the effect of the combination group was better than the PSDS group.Conclusions Combination of PSDS with smecta enema treatment for children with autumn diarrhea has significant effect,but enough attention should be paid to peri-anal nursing.

2-(3-benzoylphenyl)propionitrile which is an important intermediate of ketoprofen was synthesized through phase-transfer catalytic by four steps, involving Friedel-crafts reaction, bromination and cyanation. Pure compound was obtained, and the content of crystal was about 98%.AIM　The content of 2-(3-benzoylphenyl)propionitrile was improved. METHODS　Phase-transfer catalytic methylation and suitable method of aftertreatment were used. RESULTS　The yield and content was both improved. CONCLUSION　Phase-transfer catalytic methylation was the best method, and suitable method of aftertreatment was essential.

Objective To explore the effect of chewing gums on gastrointestinal function of rectal cancer patients undergoing surgical operations.Methods One hundred rectal cancer patients were randomized equally into the control group and test group:the former received routine nursing care and the latter began to chew the chewing 2-3 gums for 4-5 times a day 2-4 hours after operation until anal passage of gas or defecation.The two groups were compared in terms of first time for anal passage of gas,first time for defecation and postoperative abdominal distension.Results The time for anal passage of gas in the test group was(62.52±19.99)h, significantly shorter than that of(70.68±19.34)h in the control group(t=2.184,P<0.05).The defecation time in the test group was (84.20±14.25 ) h,also significantly shorter than that of the control group(t=-2.204,P<0.05).The incidence of abdominal distension in the test group was significantly lower than that in the control group(8.00%vs.26.00%;χ2=5.741,P<0.05).Conclusion Chewing the gums,as an adjunctive therapy,is effective for the recovery of gastrointestinal function after operations on rectal cancer.

Objective To evaluate the clinical efficacy of procedure for prolapse and hemorrhoids (PPH)plus Milligan-Morgan methods for circumferential mixed hemorrhoid.Methods A total of 74 cases with circumferential mixed hemorrhoid were treated by PPH plus Milligan-Morgan methods.Results The anal form of all cases were changed correctly.There was no complication such as anal edema,incontinence,anal stenosis,postoperative massive bleeding and infection.Conclusion PPH plus Milligan-Morgan methods is a safe and effective way for circumferential mixed hemorrhoid.This way can decrease postoperative complications and improve the curative effect.

Objective To observe the clinical effect of low-dose dexmedetomidine plus tramadol hydrochloride for patient-controlled interscalene analgesia (PCIA) after laparoscopic hysterectomy.Methods Seventy ASA Ⅰ ～ Ⅱ female patients with elective laparoscopic hysterectomy were randomly divided into two groups:the tramadol hydrochloride PCIA group(group A),and the dexmedetomidine plus tramadol hydrochloride PCIA group(group B),35 cases in each group.Visual analog scale (VAS),Ramsay scores,Sleepiness scale and the tramadol consumption were recorded.And the adverse events such as nausea and vomiting,dizziness and respiratory depression were observed.Results All patients got good analgesia in both two groups,VAS scores ＜ 4.In group B,VAS scores of postoperative 24h and 48h were (3.2 ±0.3) (2.7 ±0.3),which were significantly lower than (3.8 ±0.4) and (3.2 ± 0.2) in group A (t24 =7.099,t48 =8.204,all P ＜ 0.05).Sleepiness scale (3.1 ± 0.7) in group B was lower than group A (4.2 ± 0.8) (t =6.122,P ＜ 0.05),while there was no difference of Ramsay scores between two groups (P ＞ 0.05).And in group B,the tramadol consumption [(625.2 ± 113.7) mg] and the intramuscular pethidine times (2.1 ±1.9) were fewer than group A[(782.9 ± 102.6)mg,(5.2 ±2.2) times] (t =6.092,6.309,all P ＜0.05).Conclusion Low-dose dexmedetomidine may improve the effect of tramadol hydrochloride PCIA after laparoscopic hysterectomy,and help to reduce the tramadol consumption and adverse effects.

Objective To investigate the mechanism of Thapsigargin in the proliferation of SW480 and provide experimental basis for development of anti-signaling therapy for patients with colon cancer by detection of intracellular calcium concentration in Thapsigargininduced human colon cell line SW480,.Methods Level of[Ca2+]was measured by fluorescence measurement with fura-2/AM,a fluorescent index of calcium.The suppression rate of SW480 cells was calculated by MTY assay.Results Thapsigargin promoted the levels of [Ca2+]from(133.26±5.17,197.46±4.62)to(436.63±5.21,766.41±3.12),and increased the suppression rate from(10.67±5.28)to(31.46±7.21).When W7 Was combined used with Thapsigargin,no significant changes were found in the levels of[Ca2+]and increment of the suppression rate.Condusion Thapsigargin might promote the proliferation of SW480 cells and lead to apoptosis.but the signaling pathway still remain to he studied.