1.Cutaneous Metastasis from Small Cell Lung Cancer Expressing Thyroid Transcription Factor-1.
Sung Hyuk MOON ; Nack In KIM ; Min Kyung SHIN
Korean Journal of Dermatology 2012;50(9):835-837
No abstract available.
Neoplasm Metastasis
;
Small Cell Lung Carcinoma
;
Thyroid Gland
2.Characteristics of Unilateral Cryptorchid Testes Treated by Orchiectomy : Analysis of 78 Cases.
Kyung Min KANG ; Chang Ho MOON ; Sung Kwang CHUNG
Korean Journal of Urology 2000;41(12):1495-1501
No abstract available.
Orchiectomy*
;
Testis*
3.Relationship between Changes in Body Mass Index and Pulmonary Function in Adults.
Eun Kyung SON ; Chang Ho YOUN ; Hae Jin KO ; Hyo Min KIM ; Kyung Min MOON
Korean Journal of Health Promotion 2011;11(3):154-159
BACKGROUND: Obesity is linked to a wide range of respiratory diseases. Several studies have shown that body weight at baseline and weight change were related to pulmonary function. The purpose of this study was to investigate the relationship between change in body mass index (BMI) and pulmonary function in adults. METHODS: Of those aged 40-64 years at baseline who had initially visited the health promotion center at one university-level hospital from January 2000 to December 2002, 499 (men: 309, women: 190) patients revisited the center over a 5-year period up to December 2009 and were enrolled in the study. Subjects were classified into 4 groups- group 1: normal-normal, group 2: normal-obese, group 3: obese-normal, and group 4: obese-obese, based on their BMI at baseline and follow-up. Forced expiratory volume in one second (FEV1), forced vital capacity (FVC) and FEV1/FVC were measured by spirometry. RESULTS: Change in FEV1/FVC was significantly associated with change in BMI for men in all 4 groups. Change in FEV1/FVC was significantly different between group 1 and 3 and between group 1 and 4. Changes in FEV1, FVC and FEV1/FVC were significantly associated with change in BMI for women in all 4 groups. Change in FEV1 was significantly different between group 3 and 4, and change in FVC was significantly different between group 1 and 3. CONCLUSIONS: These results suggest that a change in BMI is negatively associated with change in pulmonary function. Obesity itself can be a risk factor for pulmonary dysfunction, and a decrease in BMI through weight reduction could reduce pulmonary dysfunction or improve pulmonary function in adults.
Adult
;
Aged
;
Body Mass Index
;
Body Weight
;
Female
;
Follow-Up Studies
;
Forced Expiratory Volume
;
Health Promotion
;
Humans
;
Male
;
Obesity
;
Risk Factors
;
Vital Capacity
;
Weight Loss
4.Prevalence and Epidemiologic Characteristics of Hypertension in a Rural Adult Population.
Joung Soon KIM ; Un Yeong KO ; Yong MOON ; Min Kyung LIM ; Min Joung KO
Korean Journal of Epidemiology 1996;18(1):55-63
To determine the prevalence and risk factors of hypertension we performed cross-sectional study in a rural area. We measured BP and body mass index(BMI), and interviewed adult residents over 30-year-old age. 337 males and 357 females participated the survey. BP was checked twice and the mean was used to determine age and sex specific mean BP and prevalence of hypertension. Prevalence of definite hypertension(BP>or=160/95 or on medication) was 14. 0% in males and 17. 7% in females. Risk factor for hypertension was analysed by multiple logistic regression; age (10years: OR=l. 7) and BMI(1 BMI unit: OR=l. 2) were positively associated with hypertension but smoking(1 pack year: OR=0.9) was shown to have inverse relationship.
Adult*
;
Cross-Sectional Studies
;
Female
;
Humans
;
Hypertension*
;
Logistic Models
;
Male
;
Prevalence*
;
Risk Factors
5.A Case of Intestinal GVHD after Allogeneic Bone Marrow Transplantation for Treatment of Severe Aplastic Anemia.
Young Myung MOON ; Jin Kyung KANG ; In Suh PARK ; Jae Bock CHUNG ; Hee Yon MOON ; Yoo Hong MIN ; Seong Tae LEE
Korean Journal of Gastrointestinal Endoscopy 1994;14(4):494-499
Bone marrow transplantation has become an accepted treatment for malignancy(particulary leukemia and lymphoma), aplastic anemia, and certain inborn errors of metabolism. In addition to the problem of severe, prolonged myelosuppression, bone marrow transplantation is associated with several unusual complications. Among the complications such as GVHD, graft rejection, interstitial pneumonia and veno-occlusive disease, involvement of the gastrointestinal tract by GVHD is associated with high graft failure and mortality. Intestinal GVHD is usually manifest clinically as voluminous secretory diarrhea accompanied by abdominal cramping, ileus, nutritional depletion, and, at times, hemorrhage. We experienced a case of severe intestinal GVHD after allogeneic marrow transplantation for treatment of severe aplastic anemia. He received bone marrow from his elder sister, HLA-matched multiparous woman and suffered from large amount of watery diarrhea with skin rash 34 days after transplantation. 1n spite of prednisolone therapy the symptom was progressed. After sigmoidoscopic mucosal biopsy, intestinal GVHD was confirmed and we tried methylprednisolone pulse therapy. Skin lesion was improved but the amount of diarrhea was increased with intermittent abdominal cramping. We tried ALG(anti-lymphocyte globulin) and conservative management but the patient did not respond the therapy. He succumbed to pneumonia and acute respiratory insufficiency complicated with GVHD, 70days after transplantation.
Anemia, Aplastic*
;
Biopsy
;
Bone Marrow Transplantation*
;
Bone Marrow*
;
Colic
;
Diarrhea
;
Exanthema
;
Female
;
Gastrointestinal Tract
;
Graft Rejection
;
Hemorrhage
;
Humans
;
Ileus
;
Leukemia
;
Lung Diseases, Interstitial
;
Metabolism, Inborn Errors
;
Methylprednisolone
;
Mortality
;
Pneumonia
;
Prednisolone
;
Respiratory Insufficiency
;
Siblings
;
Skin
;
Transplants
6.The development of industrial health information management system.
Sung Hyun HAN ; Young Moon CHAE ; Young Hahn MOON ; Jaehoon ROH ; Kyung Jong LEE ; Myung Wha CHO ; Hae Young MIN
Korean Journal of Occupational and Environmental Medicine 1992;4(2):181-189
No abstract available.
Information Management*
;
Occupational Health*
7.Mucoceles in Post-operative Maxillary Sinuses: CT and MR Findings.
Moon Hee HAN ; Man Chung HAN ; Kee Hyun CHANG ; Kyung Mo YEON ; Yang Gi MIN
Journal of the Korean Radiological Society 1994;30(3):431-435
PURPOSE: This study describes the CT and MR findings of mucoceles occurred in the post-operative maxillary sinuses. MATERIALS AND METHODS: CT and/or MR of 19 maxillary mucoceles in 16 patients who had been operated by CaldwelI-Luc procedure were reviewed. CT scans were performed after contrast enhancement in axial and coronal planes with 5mm thickness. Three cases were studied with a 2.0 T or 0.5 T MRI, which demonstrated multi-compartment lesions. RESULTS: The lesions were bilateral in 3 cases. Compartmentalization of the antral cavity was seen in 7 out of 19 involved sinuses. Surgical bone defect of the anterior wall was the most frequent route of extension (11 cases) and extension into the infratemporal fossa with erosion of posterolateral wall was seen in 7 lesions. In 6 cases, the lesions involved orbit. The expansile and erosive bone changes were localized in every case. In one case with multi-compartment lesion, both T1- and T2-weighted MR images showed different signal intensities in each compartment which represented different protein concentration. CONCLUSION: Post-operative maxillary mucocele showed CT findings of localized erosion and bulging most frequently at the anterior wall in which the bone windows were made during the previous surgery. Post-operative compartmentalization of maxillary antrum may cause eccentric expansion of mucocete and each compartment may show different signal intensities on MR.
Humans
;
Magnetic Resonance Imaging
;
Maxillary Sinus*
;
Mucocele*
;
Orbit
;
Tomography, X-Ray Computed
8.A Case of Ehlers - Danlos Syndrome.
Seong Min PARK ; Doo Chan MOON ; Kyung Sool KWON ; Tae Ahn CHUNG ; Kwang Man KIM
Korean Journal of Dermatology 1988;26(3):426-431
We presented a case of Ehlers-Danlos syndrome(ED syndrome) in s 21-year- old male, who had hyperextensibility of skin, skin fragility, and cigarette paperlike atrophic scars with no joint problems since infancy. There was a family history which was suggestive of autosomal dominant trait. Microscopic examination of the skin biopsy specimen from the normal appearing skin on the right forearm showed no abnormal appearance. In this case the manifestations of skin including marked hyperextensibility might be in accord with type I (gravis) ED syndrome, but the joint manifestation did not correspond to this type. It might be hard to classify this case according to the eleven types of ED syndrome. Wed rather consider this case as a. mixed form of type I and type Il ED syndrome.
Biopsy
;
Cicatrix
;
Ehlers-Danlos Syndrome
;
Forearm
;
Humans
;
Joints
;
Male
;
Skin
;
Tobacco Products
9.Detection of Antibodies to Human Keratinocytes in Vitiligo by Western blotting.
Jin Moon KANG ; Soo Min KIM ; Seung Kyung HANN
Korean Journal of Dermatology 1998;36(4):589-594
BACKGROUND: It has been reported that immunological mechanisms may play an important role in the pathogenesis of vitiligo. Cellular degeneration in vitiligo is not limited to melanocytes but includes keratinocytes and probably whole epidermal melanin units. OBJECTIVE: The purpose of this study was to demonstrate the presence of anti-keratinocyte antibodies and the relationship between the level of antibodies and activity of the disease. METHODS: We analyzed the level of anti-keratinocyte antibodies in 13 patients with non-active, segmental vitiligo and 7 patients with active, non-segmental vitiligo by Western blotting. RESULTS: Using the Western blot method, we demonstrated the occurrence of anti-keratinocyte antibodies with keratinocyte cytoplasm. Anti-keratinocyte antibodies were more reactive in patients with active, non-segmental vitiligo than in those with non-active, segmental vitiligo. CONCLUSION: These results may be a secondary phenomenon to keratinocyte damage with concurrent occurrence of melanocyte destruction. However, the level of these antibodies may represent the acitivity of vitiligo.
Antibodies*
;
Blotting, Western*
;
Cytoplasm
;
Humans*
;
Keratinocytes*
;
Melanins
;
Melanocytes
;
Vitiligo*
10.Supraclavicular BCG Lymphadenitis Noted at 21 Months after BCG Vaccination Confirmed by a Molecular Method.
Min Hyun LEE ; Moon Hee CHAE ; Kyoung Un PARK ; Hye Kyung CHO
Korean Journal of Pediatric Infectious Diseases 2014;21(2):139-143
Bacille Calmette-Guerin (BCG) lymphadenitis is the most common complication of BCG vaccination. It commonly occurs in infants aged <6 months involving ipsilateral axillary lymph nodes. We described BCG lymphadenitis in a 22-month-old boy presenting swelling of left supraclavicular lymph node that was confirmed by real-time polymerase chain reaction (PCR) and the multiplex PCR targeting the region of difference (RD).
Humans
;
Infant
;
Lymph Nodes
;
Lymphadenitis*
;
Male
;
Multiplex Polymerase Chain Reaction
;
Mycobacterium bovis*
;
Real-Time Polymerase Chain Reaction
;
Vaccination*