Basal cell carcinoma is the most common skin cancer, but it rarely metastasizes. Metastatic basal cell carcinoma (MBCC) is rare in terms of incidence as well as absolute numbers. We present a case of 67-year-old woman who had a dirty oozing, ulcerated, tumor mass on the vertex and suffered from dyspnea and mild lumbago. The diagnosis of MBCC was based on clinical, radiological, and histopathological findings. To our knowledge, the occurrence of MBCC has not been reported in the Korean literatures. So we reported herein this case of MBCC of the lung and the bone.
Aged ; Carcinoma, Basal Cell* ; Diagnosis ; Dyspnea ; Female ; Humans ; Incidence ; Low Back Pain ; Lung ; Skin Neoplasms ; Ulcer

OBJECTIVE: To assess whether there is correlation between serum concentrations of vascular endothelial growth factor(VEGF) and development of preeclampsia. METHODS: The authors measured serum concentrations of VEGF in 18 preeclamptic women admitted to Sanggye Paik Hospital, Inje University from February 1999 to September 1999 and in 18 normotensive pregnant women matched in maternal age, maternal body weight, parity and gestational age. VEGF was measured with a sensitive and specific enzyme immunoassays. RESULTS: VEGF was detected in all pregnant women. The results of this study showed that the serum concentrations of VEGF are significantly higher in the preeclamptic women than in the normotensive pregnant women. The values of median and range of VEGF are 7.74 ng/ml and 0.5-35.94 ng/ml in the preeclamptic women, and 0.5 ng/ml and 0.5-2.16 ng/ml in the normotensive pregnant women, respectively. There is significant difference in serum concentrations of VEGF between two groups(p<0.001, Mann-Whitney U test). Positive correlations were noted between VEGF concentraions and the systolic and diastolic blood pressure(Systolic BP: r2=0.688, Diastolic BP: r2=0.722, Spearman rank test). CONCLUSION: The high serum concentration of VEGF is thought to be important in the development or pathophysiologic mechanism of preeclampsia. In the next study, the prospective analysis will be necessary to identify whether serum concentration of VEGF is abnormally high in early gestational pregnant women who are destined to preeclampsia.
Body Weight ; Female ; Gestational Age ; Humans ; Immunoenzyme Techniques ; Maternal Age ; Parity ; Pre-Eclampsia ; Pregnant Women ; Vascular Endothelial Growth Factor A*

OBJECTIVE: To determine whether there is correlation between serum concentrations of lipoproteins (VLDL, HDL, LDL) and development of preedampsia. METHODS: The authors measured serum concentrations of lipoproteins(VLDL, HDL, LDL) and lipids(which are major components of lipoproteins) in 12 preeclamptic women admitted to Sanggye Paik Hospital, Inje University from March 1999 to August 1999 and 12 normal pregnant women matched in age, weight, parity and gestational age. RESULTS: The first, the values of median and range of VLDL are higher in preeclamptic women than in normal pregnant women(preeclamptic women : 244mg/dL & 124-521mg/dL, normal pregnant women : 149mg/dL & 68-308mg/dL, p=0.0005). But there are no difierences in serum concentrations of HDL(high-density lipoprotein) and LDL(low-density lipoprotein) between two groups. The second, the values of median and range of triglyceride and free fatty acids are higher in preedamptic women than in normal pregnant women(preeclamptic women : triglycerides : 305.5mg/dL & 231-545mg/dL, free fatty acids : 1,333mmol/L & 842- 1523mmol/L, normal pregnant women,: triglycerides : 239mg/dL & 151-414mg/dL, free fatty acids : 806.5mmol/L & 314-1517mmol/L, p=0.019 in triglycerides and p=0.033 in free Fatty acids). But the serum concentrations of cholesterol are similar in two groups. CONCLUSIONS: Overall, the results of this study showed the serum concentrations of VLDL, triglycerides and free fatty acids are significantly higher in preeclamptic women than in normal pregnant women. So, the high serum concentration of VLDL is thought to be important in the pathogenesis of preeclampsia. In the next study, the prospective analysis will be necessary to identify whether serum concentration of VLDL is abnormaUy high in early gestational pregnant women who are destined to preeclamsia. Also, the measurement of pI 5.6 isoelectric form of albumin which is suggested to prevent VLDL toxicity will be necessary.
Cholesterol ; Fatty Acids, Nonesterified ; Female ; Gestational Age ; Humans ; Lipoproteins* ; Parity ; Pre-Eclampsia* ; Pregnant Women ; Triglycerides

No abstract available.
Humans ; Pneumonectomy*

Intraosseous lipoma is one of the rarest primary benign tumors of bone and it is characterised by a neoplastic overgrowth of univacuolar fat cells. The incidence is less than one per 1,000 bone tumors. Most commonly, long bones are affected, with a tendency for metaphyseal involvement. Because of its rarity and nonspecific clinicopathologic findings, biopsy is needed for accurate diagnosis. Currettage and bone-grafting is the treatment of choice if the lesion is painful or if structural stability is threatened. We report 3 cases of intraosseous lipoma in long tubular bones with review of literatures. Two cases were treated by surgical intervention and the other case by conservative management.
Adipocytes ; Biopsy ; Diagnosis ; Incidence ; Lipoma*

Dupuytren's contracture is characterized by a proliferative fibroplasia and contracture of the palmar fascia with resultant deformity of hand and finger. It is most common in those of Scandinavian and Celtic origin but it is very rare in the orientals. We experienced 30 hands of 21 patients from January 1985 to December 1995 in Soonchunhyang University Hospital. Among 21 patients, operative treatment was done in 28 hands of 19 patients. Partial fasciectomy was done in 24 hands and complete fasciectomy was done in 4 hands. The longitudinal straight skin incision was done in 14 cases and the transverse or Zig-Zag incision was done in 12 cases. Average follow-up period was 24 months. The results of the operative treatment were classified by Honner's classification. Excellent result was obtained in 16 cases (57%), good in 8 (29%), fair in 3 (11%), poor in 1 (3%). The complications were 5 cases as follows; recurrence 2, skin defect 1, hypoesthesia 2. In conclusion, partial fasciectomy utilizing longitudinal straight incisions overlying diseased area is suggested as one of the good method for the treatment of Dupuytren s contracture.
Classification ; Congenital Abnormalities ; Contracture ; Dupuytren Contracture* ; Fascia ; Fingers ; Follow-Up Studies ; Hand ; Humans ; Hypesthesia ; Recurrence ; Skin

No abstract available.
Autografts* ; Cartilage* ; Transplantation, Autologous*

The incidence of intertrochanteric fracture of the femur in the elederly patient was lower than young in korea because of low average span and causes of injuries. But recently, the incidence is progressively in creased due to prolongation of korean average life span and improvement of residental enviroment. The mortality and morbidity are higher in spite of various treatment methods because of associated diseases and the poor general conditions of patients. Total 102 cases of intertrochanteric fracture of the femur were treated at the Department of Orthopaedic Surgery of Soonchunhyang University Hospital during the period from January, 1978 to December, 1985. Among them, 67 cases(65.7%) were over 60 years in the age, and of which 55 cases(one case was bilateral) were followed from 8 months to 3 years and 4 months(Average 14.7 months). The results were as followes: l. Out of 54 patients, 33 patients were female and the mean age was 74 years. 2. The most common cause is the injury from slip down and the ratio between in-door injury to out-door injury was 1.7: l. 3. The 41 cases(74%) out of the 55 cases were operated within 2 weeks after the accident, 35 cases were treated by Richard compression hip screw, 11 cases were by intramedullary nailing, and 9 cases were by multiple pinning. The multiple pinning were usually tried to patients of poor general condition, which was needed to shorten the operation times. 4. The mean duration of multiple pinning operation time was 1 hour 12 minutes, intramedullary nailing operation time was 1 hour 47 minutes and Richard compression hip screw operation time was 2 hour 42 minutes. 5. Among 55 cases, 20 cases(36%) were complicated.
Aged ; Female ; Femur ; Fracture Fixation, Intramedullary ; Hip ; Humans ; Incidence ; Korea ; Mortality

Locoregional recurrence (LRR) in breast cancer poses significant challenges due to its association with biologically resistant disease and a high likelihood of concurrent occult systemic disease. Despite advancements in local and systemic therapies, LRR affects a substantial percentage of patients, leading to poorer prognosis compared to those with primary breast cancer. Therefore, a comprehensive review of systemic treatment strategies following LRR is warranted to address the gaps in our understanding and improve patient outcomes. This review explored factors influencing the prognosis of breast cancer LRR. In particular, we evaluated the benefits of systemic treatment options post-resection and proposed an optimal treatment algorithm.

Locoregional recurrence (LRR) in breast cancer poses significant challenges due to its association with biologically resistant disease and a high likelihood of concurrent occult systemic disease. Despite advancements in local and systemic therapies, LRR affects a substantial percentage of patients, leading to poorer prognosis compared to those with primary breast cancer. Therefore, a comprehensive review of systemic treatment strategies following LRR is warranted to address the gaps in our understanding and improve patient outcomes. This review explored factors influencing the prognosis of breast cancer LRR. In particular, we evaluated the benefits of systemic treatment options post-resection and proposed an optimal treatment algorithm.