No abstract available.
Leiomyoma*

No abstract available.
Esophageal and Gastric Varices* ; Hemorrhage*

BACKGROUND: For the diagnoais of atopic dermatitis(AD) an array of basic and minor clinical features proposed by Hanifin and Rajka were in common use. However, there have been some disputes in the diagnostic significance of minor clinical features of AD due to ethni. differences, variance in definitions, materisls and methods, OBJECTIVES: The purpose of the present study was to evaluate the dignostic significance of total 38 minor clinical features of AD in Korean children. Most of them wefe roposed by some authors in the literature and the remainder by ourselves based on our clinical experienes. METHODS: The frequency of these features was studied in 48 patieni s with typical AD compared to that in 89 control subjects. The age of all studied individuals ranged from 2 to 12 years. RESULTS: Thirteen of these was including xerosis, perifollicular acccntuation, frontal lichenification, anterior neck folds, eyelid eczema, Dennie-Morgan folds, auricular fiss are/eczema, pityriasis alba, vertral wrist eczema, infragluteal eczema, sandpaper-like skin lesion of yelbow/knee/lateral malleolus, white dermographism, and scalp scaling were shown to be of mueh diag nostic significance(P<0,001). CONCLUSION: We propose that above-mentioned 13 monor features may be a valuable guideline for the large scale field survey on the incidence and prevalence of AD in Korea children.
Child ; Dermatitis, Atopic* ; Dissent and Disputes ; Eczema ; Eyelids ; Humans ; Incidence ; Korea* ; Neck ; Pityriasis ; Prevalence ; Scalp ; Skin ; Wrist

BACKGROUND: Three age-depedent clinical phases(infantile, childhood and adult phase) of atopic dermatitis(AD) were recognized. We think that for t he diagnosis of AD there seems to be some differences in minor clinical features of diagnosic significance according to each phase, yet only a few studies about them. OBJECTIVES: The purprrse of the present study was to evalute the diagnostic significance of total 39 minor clinical features of AD in Korean adolescenc and adult popluation, all but only skin were proposed by our previous study for Korean children. METHODS: The frequeney of 39 minor clinical features wistudied in 82 patients with typical AD compared to that in 109 control subjects. The age all studied individuals ranged from 13 to 42 years. Furthermore, some characteristic micro features of AD in them were compared with those from our previous study for Korean children. RESULTS: Twenty-seven minor features including xerosis, peifolhcular accentuation, frontal lichenification, anterior neck folds, eyelid eczema, Dennie-Mogan folds, auricular fissure/eczema, pityriasis alba, ventiral wrist eczema, infragluteal eczcm, sandpaper-like skin lesions on elbow/knee/lateral malleblus, white dermographism, scalaling, Hertoghes sign, orbital darkening, cheilitis, facial erythema/pallor, hyperlinear paln, ichthyosiform skin lesions, nipple eczema, nummular eczema, pompholyx, itchy hyperker totic lesions of dorsal hands, knuckle dermatitis of hands, hangnail, non-specific hand/foot dermatitis, chronic dermatophytosis were shown to be of much diagnostic signiic, nce(P<0.001). CONCLUSION: We think tiat 13 minor features such as Hert piges sign, cheilitis, facial erythe- mapallor, hyperlinear ichthyosiform skin lesions, ripile eczema, nummular eczema, pompholyx, itchy hyperkpratotic lesions of dorsal hands, kzukle dermatitis of hands, hangnail, non-specific hand/foot dermatitis, chronic dermato h tosis are specific for Korean adolescence and adult population with AD. Taken together, to propose that these 13 minor features be added to a gardeline for the large scale field sirvy on the incidence and prevalence of AD in the Korea adolescence and adult population.
Adolescent* ; Adult* ; Cheilitis ; Child ; Dermatitis ; Dermatitis, Atopic* ; Diagnosis ; Eczema ; Eczema, Dyshidrotic ; Eyelids ; Hand ; Humans ; Incidence ; Korea* ; Neck ; Nipples ; Orbit ; Pityriasis ; Prevalence ; Skin ; Tinea ; Wrist

OBJECTIVE: The conventional methods to determine fetal genetic status, such as amniocentesis or chorionic villi sampling(CVS) have small procedure-related risk of abortion. Recently, several researchers reported that fetal genetic status, such as sex, can be confirmed by fetal nucleated erythrocytes in maternal blood and this method might reduce such risk. Therefore, in this study, we attempted to determine the basic fetal genetic status, sex, with fetal nucleated erythrocytes. METHODS: In twelve pregnant women who undertook amniocentesis or CVS, 20 ml of venous blood was drawn immediately before the procedure and the nucleated erythrocytes were recovered by magnetic activated cell sorting(MACS). After MACS, DNA was extracted from 200 microliter of sample and single nucleated erythrocyte was obtained by additional procedure, immunostaining, and microdissection. After recovery of nucleated erythrocytes by microdissection, nested polymerase chain reaction(PCR) and fluorescent PCR of amelogenin gene were performed to identify the fetal gender. RESULTS: The DNA of enriched erythrocytes after MACS could identify the fetal gender in the 58.3% of the samples by nested PCR. After the recovery of single nucleated erythrocyte by MACS, immunostaining and microdissection, the minute DNA in a single cell could be amplified by primer extension preamplification(PEP), nested PCR, and fluorescent PCR. Fetal genders were correctly identified in 8 out of 12 (66.7 %). CONCLUSION: Through this study, we could conclude that fetal nucleated erythrocytes in maternal blood might be sufficient sample to determine fetal sex. And single cell isolation by microdissection could get the better results than nested PCR after MACS only. However, in spite of the pregnancy of male fetus, female specific bands were obtained after nested PCR of amelogenin in several cells, which might suggest that part of nucleated erythrocytes in maternal blood might be maternal origin. Therefore, to determine fetal genetic condition by nucleated erythrocytes in maternal blood, further improvements of methods to identify the nucleated erythrocytes of fetal origin are needed.
Amelogenin ; Amniocentesis ; Cell Separation ; Chorionic Villi ; Diagnosis* ; DNA ; Erythroblasts* ; Erythrocytes ; Female ; Fetus ; Humans ; Male ; Microdissection ; Polymerase Chain Reaction ; Pregnancy ; Pregnant Women

No abstract available.
Factor VIII* ; Hemophilia A* ; Humans

A case of isolated Crohn's disease of appendix is reported. It is a rare disease which commonly mimics the symptoms of acute appendicitis. Review of 221 identical cases previously reported in the world literature revealed slight male predominance(1.17:1) and peak age of incidence in the third decade(24.3 yrs). In contrast to typical Crohn's disease, the rate of postoperative fistula and recurrence was minimal; 1.0% and 3.8%, respectively. Due to these differences, many consider it to be a separate disease entity from Crohn, and a new diagnostic term - "Idiopathic Granulomatous Appendicitis" - has gained wide acceptance in recent years.
Appendicitis* ; Appendix* ; Crohn Disease* ; Fistula ; Humans ; Incidence ; Male ; Rare Diseases ; Recurrence

Bronchioloalveolar carcinoma may present with a variety of radiographic and clinical appearances. The authors reviewed the radiographs of 17 patients with pathologically proven bronchioloalveolar carcinoma, retrospectively. Seven cases were of the localized form. Among the seven five showed a localized mass and two showed localized consolidation. Ten cases were of the diffuse form. Among the ten, three showed diffuse nodules, two showed diffuse consolidation, and five showed a combined pattern of nodules and consolidations. Progression of disease was observed in 9 patients. In these cases, localized forms progressed to a diffuse forms and nodular patterns progressed to a consolidation pattern. Seven cases of the diffuse form were given antituberculous medications on hospital admission. In summary, bronchioloalveolar carcinoma has varied radiographic patterns, and often mimicks other pulmonary diseases such as pulmonary tuberculosis.
Adenocarcinoma, Bronchiolo-Alveolar* ; Humans ; Lung Diseases ; Retrospective Studies ; Tuberculosis, Pulmonary

Arteriovenous mafformation(AVM) of female pelvic organ is a rare disease of unknown cause. The authors' report a case of pelvic AVM which was incidentally found during US examination of the patient with choriocarcinoma after chemotherapy. The real-time sonography revealed several cystic lesions around the uterus with adjacent dilated tortuous vessels. The color Doppler sonography depicted abundant blood flow mixed with red and blue colors within the cystic lesions and rapid turbulent systolic and diastolic flows. CT showed well-enhancing round vascular lesions with elongated vessels in the pelvis, and MRI depicted signal-void cystic lesions on both T1 and T2 weighted images with small portions of high intensity within the lesions on T2 weighted image. The angiography revealed pelvic AVM fed by tortuous uterine and vaginal arteries with a dilated draining vein
Angiography ; Arteries ; Arteriovenous Malformations* ; Choriocarcinoma ; Drug Therapy ; Female ; Humans ; Magnetic Resonance Imaging ; Pelvis ; Pregnancy ; Rare Diseases ; Uterus ; Veins

Arteriovenous mafformation(AVM) of female pelvic organ is a rare disease of unknown cause. The authors' report a case of pelvic AVM which was incidentally found during US examination of the patient with choriocarcinoma after chemotherapy. The real-time sonography revealed several cystic lesions around the uterus with adjacent dilated tortuous vessels. The color Doppler sonography depicted abundant blood flow mixed with red and blue colors within the cystic lesions and rapid turbulent systolic and diastolic flows. CT showed well-enhancing round vascular lesions with elongated vessels in the pelvis, and MRI depicted signal-void cystic lesions on both T1 and T2 weighted images with small portions of high intensity within the lesions on T2 weighted image. The angiography revealed pelvic AVM fed by tortuous uterine and vaginal arteries with a dilated draining vein
Angiography ; Arteries ; Arteriovenous Malformations* ; Choriocarcinoma ; Drug Therapy ; Female ; Humans ; Magnetic Resonance Imaging ; Pelvis ; Pregnancy ; Rare Diseases ; Uterus ; Veins