Hyperkeratosis of the nipple and areola is a rare skin disordr characterized clinically by thickening and discoloration of the skin of the areola and/or nipple and pathoiog cally by papillomaosis or acanthosis-nigricans like changes. We report a case of hyperkeratosis of the nipple and areola occuring in a woman with no underlying endocrinopathy and no other additional hyperkeratotic conditions. Ttie iresent case seems to be the nevoid form by the Levy-Franckel classification. Treatment with topical medications including steroids and keratolytic agents produced no improvement. Therefore we recommeneded surgical excision because the paient was greatly disturbed by the appearance of the lesions. Surgical excision and full thickness skin graft were performed sucessfully.
Classification ; Female ; Humans ; Keratolytic Agents ; Nipples* ; Skin* ; Steroids ; Transplants*

The coexistence of pheochromocytoma and renal artery stenosis has been recognized since 1958, but it is rare. We have experienced an anesthetic management of 43-year-old female patient of renovascular hypertension associated with right adrenal pheochromocytoma. Proper preoperative preparation, sufficient sedation, smooth induction, complete analgesia and good muscle relaxation were very important. Relative cardiovascular stability was achieved with sodium nitroglycerine, sodium nitroprusside and verapamil during tumor manipulation. After the tumor was removed, we could control the hypotension with dopamine, dobutamine, crystalloid and colloid. On the operative field there was no definite anatomic stenosis of renal artery and it was suggested that leakage of catecholamines from pheochromocytoma causes functional, reversible spasm of renal artery and thus renovascular hypertension.
Adult ; Analgesia ; Catecholamines ; Colloids ; Constriction, Pathologic ; Dobutamine ; Dopamine ; Female ; Humans ; Hypertension, Renovascular* ; Hypotension ; Muscle Relaxation ; Nitroglycerin ; Nitroprusside ; Pheochromocytoma* ; Renal Artery ; Renal Artery Obstruction ; Sodium ; Spasm ; Verapamil

PURPOSE: The aim of this study was to determine the risks of a hemorrhoidectomy in patients requiring long-term anticoagulation. METHODS: Between March 1998 and February 2001, 13 patients requiring long-term oral anticoagulation because of prosthetic valve replacement (n=4), atrial fibrillation (n=7), and coronary artery disease (n=2) underwent a hemorrhoidectomy at Seoul National University Hospital. We performed a retrospective analysis on these patients regarding the results of the hemorrhoidectomy. The control group consisted of 148 patients without any medical problems who had undergone a hemorrhoidectomy during the same period. Patients on anticoagulation stopped their oral medication three days before the operation and full intravenous (IV) heparinization was commenced. Heparin was stopped six hours before the operation and restarted postoperatively, and warfarin was re-started on the evening of postoperative day 1. The hemorrhoidectomy consisted of excising three main piles, followed by submucosal excision of all intervening piles. Student's t-test and Fisher's exact test were used for statistical analysis. RESULTS: The PTs (prothrombin times) of the anticoagulation group and the control group obtained at admission were INRs (international normalized ratios) of 1.75+/-0.54 and 1.04 0.08, respectively (P=0.0005). After discontinuation of oral medication and full IV heparinization, the INR of the anticoagulation group at the time of operation was 1.06+/-0.09, which was not statistically different from the PT (INR) of the control group at admission (P=0.603). There were two cases of postoperative bleeding requiring blood transfusions in the anticoagulation group (15.4%), and four cases of postoperative bleeding requiring blood transfusions in the control group (2.7%), but there was no statistical difference between the rates for the two groups (P=0.075). The mean postoperative hospital stays were 6.69+/-3.68 and 3.64+/-2.98 for the anticoagulation and control groups, respectively (P=0.074). Postoperative analgesic requirements and urinary difficulty were similar in both groups (P=0.478 and 0.397, respectively). No systemic thromboembolism in both groups, and there was no bacterial endocarditis or valvular thrombosis was seen in patients with prosthetic heart valves. CONCLUSIONS: Our results indicate that patients taking oral warfarin for anticoagulation may safely undergo a hemorrhoidectomy after strict heparinization.
Atrial Fibrillation ; Blood Transfusion ; Coronary Artery Disease ; Endocarditis, Bacterial ; Heart Valves ; Hemorrhage ; Hemorrhoidectomy* ; Heparin ; Humans ; International Normalized Ratio ; Length of Stay ; Retrospective Studies ; Seoul ; Thromboembolism ; Thrombosis ; Warfarin

Anesthesiologists are faced with a growing number of patients in need of cardiac pacing with symptoms of increasing complexity. Because intraoperative pacemaker malfunction can lead to sudden death, it is important for the anesthesiologists to possessthe information necessary to evaluate and treat such patients. On the other hand, torsade de pointes, a particular form of life-threatening polymorphic ventricular tachycardia, is known to be elicited in patients with cardiac pacemakers in the setting of abnormally long QT intervals, decreased heart rate and severe electrolyte disturbances, notably hypokalemia. We herein report a case of intraoperative torsade de pointes that was triggered by pacemaker malfunction-induced bradycardia in a patient with a VVI-type cardiac pacemaker, whose serum potassium and magnesium level were low preoperatively. (Korean J Anesthesiol 1999; 37: 164~167)
Bradycardia ; Death, Sudden ; Hand ; Heart Rate ; Humans ; Hypokalemia ; Magnesium ; Potassium ; Tachycardia, Ventricular ; Torsades de Pointes*

A 65-year-old male presented with pain in his right medial calf. An imaging study revealed no acute lesions, and a diagnosis of saphenous neuralgia was made by a nerve conduction study. He received temporary pain relief with saphenous nerve blocks twice in a one-week interval. Pulsed radiofrequency neuromodulation reduced pain to 10% of the maximal pain intensity. At 6 months after the procedure, the pain intensity was not aggravated even without medication. Pulsed radiofrequency neuromodulation of the saphenous nerve may offer an effective and minimally invasive treatment for patients with saphenous neuralgia who are refractory to conservative management.
Aged ; Humans ; Male ; Nerve Block ; Neural Conduction ; Neuralgia

The changes of arterial carbon dioxide partial pressure considerably influence cerebral blood flow and different anesthetic agents have different effects on cerebrovascular physiology. However the importance of these differences in neuroanesthetic practice are unclear. Transcranial Doppler ultrasonography allows the noninvasive direct measurements of cerebral blood flow velocity and direction in the basal brain arteries. The authors performed transcranial Doppler ultrasonography to measure the blood flow velocity of middle cerebral artery in 12 patients who were anesthetized with 10 mcg/kg of fentanyl and 66 % nitrous oxide in oxygen(fentanyl group) and 12 patients with 1.0 vo1% isoflurane and 66 % nitrous oxide in oxygen(isoflurane group) during normocapnia(P(ET)CO(2)=38 mmHg) and hypocapnia(P(ET)CO(2)=28 mmHg)state. The carbon dioxide reactivity was expressed as the changes in mean blood flow velocity per unit changes in endtidal carbon dioxide partial pressure(P(ET)CO(2)). Mean blood flow velocity of middle cerebral artery decreased from 46.6+/-8.9 cm/s to 30.0+/-5.3 cm/s in the fentanyl group and 42.7+/-5.6 cm/s to 32.5+/-4.6 cm/s in the isoflurane group as the P(ET)CO(2) decreased from 38 mmHg to 28 mmHg. There was a significant difference between the CO2 reactivity of fentanyl group(1.7+/-0.7 cm/s/mmHg) and isoflurane group(1,0+/-0,2 cm/s/mmHg) (p<0.05). It is concluded that hyperventilation is more likely to affect cerebral blood flow during fentanyl-nitrous oxide anesthesia than during isoflurane-nitrous oxide anesthesia.
Anesthesia ; Anesthetics ; Arteries ; Blood Flow Velocity ; Brain ; Carbon Dioxide ; Fentanyl* ; Humans ; Hyperventilation ; Isoflurane* ; Middle Cerebral Artery ; Nitrous Oxide ; Partial Pressure ; Physiology ; Ultrasonography, Doppler, Transcranial

BACKGROUD: It is known that patients with depression can have physical and social dysfunction. Even though adolescents spend most of their time in school, researches on the relationship between adolescent depression and school adjustment are lacking. Therefore, this research surveys depression of adolescents and deals with the relationship between depression and school adjustment or school achievement. METHOD: Questionnaires were distributed to 572 students in one coed high school located in Incheon. Depression tendency was based upon BDI as cut off point 21. School adjustment was based on school related adjustment scale and the dass standing following the first semester. RESULTS: 25% (143) of 572 responses belonged to the depression tendency group. The school related adjustment scale of the depression tendency group averaged 80.06 14.78, while that of the non-depression tendency group averaged 91.78 14.98. The relationship between depression tendency and school adjustment was statistically significant(P<0.001). The relationship between depression tendency and school lifereated adjustment, school environment related adjustment, school friend related adjustment, school teacher related adjustment or school instruction-related adjustment was statistically significant(P<0. 001). In addition, the relationship between depression tendency and dass standirg was statistically significant (P<0.001). CONCLUSIONS: There was a significant relationship between depression tendency and school adjustment or school achievement. As a result, family physicians as primary care physicians need to consider examination of psychiatric symptoms such as depression tendency as well as physical symptoms, when consulting with adolescents who have trouble adjusting to school or those who bave low school achievements.
Adolescent ; Depression* ; Friends ; Humans ; Incheon ; Physicians, Family ; Physicians, Primary Care ; Surveys and Questionnaires

No abstract available.
Incidence

OBJECTIVE: To investigate nationwide statistics on flow-diverting stent usage for cerebral aneurysm treatment and related mortality data.METHODS: We requested data extraction from the National Health Insurance Service claims database using electronic data interchange codes (J3207064, J3207073). Patient and hospital information as well as death statistics were collected from the database.RESULTS: A total of 169 procedures were performed using flow-diverting stents for cerebral aneurysm treatment from November 2014 to December 2016 in Korea. The majority of primary diagnosis was unruptured intracranial aneurysm. During the study period, nine subjects died, including one patient initially diagnosed with subarachnoid hemorrhage. The crude mortality rate was 5.3%. Five patients died within one month after the procedure; therefore, the estimated periprocedural mortality rate was 3.0±1.3%. The mortality rate as of the last day of 2016 was 6.3±2.1%.CONCLUSION: In a 171 person-year follow-up in a Korean series, nine deaths occurred after flow-diverting stent treatment. The crude mortality rate in Korea (5.3%) was higher than that reported in a previous meta-analysis (3.8%).
Diagnosis ; Follow-Up Studies ; Humans ; Intracranial Aneurysm ; Korea ; Mortality ; National Health Programs ; Stents ; Subarachnoid Hemorrhage

Twenty-eight patients with 20 tibia fractures and 8 femur fractures were treated with external fixation. The average age at fracture was 10 years 10 months ranging from 5 years to 17 years 6 months. Of 28 fractures, 6 were closed fractures and 22 were open fractures. The average follow-up of these children was 23 months. Monofixators were used in 12 fractures and Ilizarov fixators in 16 fractures. The average time to healing of the fractures was 14.6 weeks(range, 6 to 44 weeks). Seven segmental bone defects(range, 2 to 17cm) were treated with the Ilizarov method of internal bone transport using the transport ring and bone grafting at the docking site. The average healing index for callus distraction was 25 days per centimeter. Seven patients had 10 major complications that necessitated additional operative procedures. There were 4 nonunions. Three patients had an infected nonunion, which was treated with the Ilizarov fixator and polymethyl-methacrylate antibiotic beads. One patient had a hypertrophic nonunion which was treated with plate fixation. Three patients who had an epiphyseal injury had shortening with angular deformity, which was treated by callus distraction. Three patients had a joint contracture, which was treated by the percutaneous tenotomy and Ilizarov fixator. The selection of the type of external fixator depends on the fracture pattern and the Ilizarov fixator is recommended for complicated fracture with severe comminution or segmental bone loss.
Bone Transplantation ; Bony Callus ; Child ; Congenital Abnormalities ; Contracture ; External Fixators ; Femur ; Follow-Up Studies ; Fractures, Bone ; Fractures, Closed ; Fractures, Open ; Humans ; Ilizarov Technique ; Joints ; Surgical Procedures, Operative ; Tenotomy ; Tibia