1.Clinical analysis of he benign gastric tumors.
Jun Min KANG ; Min Hyuk LEE ; Ik Su KIM
Journal of the Korean Surgical Society 1992;43(1):15-23
No abstract available.
2.An experimental study on enhanced antitumor effect of cyclophosphamide by methylxanthines human gastric cancer cells(NUGC-4).
Jae Jun KIM ; Min Hyuk LEE ; Kyung Bal HUR
Journal of the Korean Cancer Association 1992;24(4):469-479
No abstract available.
Cyclophosphamide*
;
Humans*
;
Stomach Neoplasms*
3.The Role of Thermography in the Diagnosis of Breast Cancer.
Journal of the Korean Surgical Society 1998;54(5):631-639
Breast thermography produces a picture of the heat emitted from the surface of the breast. And abnormal temperature over the breast has been suggested as an indicator of malignancy. The mechanisms for the heat production at the area of the skin over the breast are suggested hypermetabolism, hypervascularization, and hyperfusion of the affected regions of the breast. The purpose of this study was to evaluate the diagnostic accuracy of breast thermography in breast cancer. One hundred thirty breast cancers and one hundred ten benign breast masses were examined by a digital infrared thermographic system (NEC San-ei, Therm Tracer 6T67) between January 1991 and December 1995. In this study, thermograms were classified as normal (Th-1), equivocal (Th-2), or abnormal (Th-3). Normal thermograms were those with normal symmetric vascularity, equivocal thermograms were those with only heat in the area of mass, and abnormal thermograms were those with heat and increased vascularity in the area of mass. Among the 110 benign breast masses, there were 98 Th-1 cases (89.1%), 2 Th-2 cases (1.8%) and 10 Th-3 cases (9.1%). Among the 130 breast cancers, there were 98 Th-3 cases (75.4%), 20 Th-2 cases (16.2%), and 12 Th-1 cases (9.2%). The sensitivity of the breast thermograms was 90%, the specificity 89.1%, and the diagnostic accuracy 89.6%. A thermal difference(deltaT) of less than 1oC was seen in 10 cases (7.7%) of breast cancer, and a deltaT of more than 1oC was seen in 120 cases (92.3%). Among the latter of a deltaT of more than 3oC was seen in 67 cases(51.4%). The correlation of the breast-cancer tumor size with deltaT was highly significant(p<0.0001). The classification of the thermographic diagnosis was found to be statistically correlated with tumor size (p<0.0001), axillary node status (p<0.001) and nuclear grade (p<0.05), but not with the presence or abscence of estrogen receptor. These results suggest that thermography is useful as a diagnostic tool for breast cancer. And that a deltaT of more than 2oC of on a breast thermogram strongly suqqests a malignancy.
Breast Neoplasms*
;
Breast*
;
Classification
;
Diagnosis*
;
Estrogens
;
Hot Temperature
;
Sensitivity and Specificity
;
Skin
;
Thermogenesis
;
Thermography*
4.Moderate to Severe Left Ventricular Ejection Fraction Related to Short-term Mortality of Patients with Post-cardiac Arrest Syndrome after Out-of-Hospital Cardiac Arrest.
Kyoung Jeen MIN ; Jin Joo KIM ; In Cheol HWANG ; Jae Hyuk WOO ; Yong Su LIM ; Hyuk Jun YANG ; Keun LEE
Korean Journal of Critical Care Medicine 2016;31(4):342-350
BACKGROUND: The aim of this study was to investigate the relationships between left ventricular ejection fraction (LVEF) and mortality and neurologic outcomes with post-cardiac arrest syndrome (PCAS) after out-of-hospital cardiac arrest (OHCA). METHODS: Patients with PCAS after OHCA admitted to the intensive care unit between January 2014 and December 2015 were analyzed retrospectively. RESULTS: total of 104 patients were enrolled in this study. The mean age was 54.4 ± 15.3 years, and 75 of the patients were male (72.1%). Arrest with a cardiac origin was found in 55 (52.9%). LVEF < 45%, 45-55%, and > 55% was measured in 39 (37.5%), 18 (17.3%), and 47 (45.2%) of patients, respectively. In multivariate analysis, severe LV dysfunction (LVEF < 45%) was significantly related to 7-day mortality (odds ratio 3.02, 95% Confidence Interval 1.01-9.0, p-value 0.047). CONCLUSIONS: In this study, moderate to severe LVEF within 48 hours after return of spontaneous circulation was significantly related to 7-day short-term mortality in patients with PCAS after OHCA. Clinicians should actively treat myocardial dysfunction, and further studies are needed.
Echocardiography
;
Humans
;
Intensive Care Units
;
Male
;
Mortality*
;
Multivariate Analysis
;
Out-of-Hospital Cardiac Arrest*
;
Passive Cutaneous Anaphylaxis
;
Retrospective Studies
;
Stroke Volume*
5.Erratum: Moderate to Severe Left Ventricular Ejection Fraction Related to Short-term Mortality of Patients with Post-cardiac Arrest Syndrome after Out-of-Hospital Cardiac Arrest.
Kyoung Jeen MIN ; Jin Joo KIM ; In Cheol HWANG ; Jae Hyuk WOO ; Yong Su LIM ; Hyuk Jun YANG ; Keun LEE
Korean Journal of Critical Care Medicine 2017;32(1):88-88
The author's affiliation should be corrected. We apologize for any inconvenience that may have caused.
6.Visual Loss in One Eye after Spinal Surgery.
Korean Journal of Ophthalmology 2006;20(2):139-142
PURPOSE: To report a patient who developed an unusual combination of central retinal artery occlusion with ophthalmoplegia following spinal surgery in the prone position. METHODS: A 60-year-old man underwent a cervical spinal surgery in the prone position. Soon after recovery he could not open his right eye and had ocular pain due to the general anesthesia. Upon examination, we determined that he had a central retinal artery occlusion with total ophthalmoplegia. RESULTS: Despite medical treatment, optic atrophy was still present at the following examination. Ptosis and the afferent pupillary defect disappeared and ocular motility was recovered, but visual loss persisted until the last follow-up. CONCLUSIONS: A prolonged prone position during spinal surgery can cause external compression of the eye, causing serious and irreversible injury to the orbital structures. Therefore, if the patient shows postoperative signs of orbital swelling after spinal surgery the condition should be immediately evaluated and treated.
Visual Acuity
;
Severity of Illness Index
;
Retinal Artery Occlusion/*complications/diagnosis
;
Postoperative Complications
;
Ophthalmoplegia/*complications/diagnosis
;
Neck Injuries/diagnosis/*surgery
;
Middle Aged
;
Male
;
Magnetic Resonance Imaging
;
Laminectomy/*adverse effects
;
Humans
;
Fundus Oculi
;
Follow-Up Studies
;
Fluorescein Angiography
;
Diagnosis, Differential
;
Cervical Vertebrae/injuries/*surgery
;
Blindness/*etiology
8.Spontaneous Ruptured Subcapsular Liver Hematoma Associated with Pregnancy.
Min Whan KOH ; Sung Jun PARK ; Kang Hyuk LEE ; Young Jin JANG ; Tae Hyung LEE
Korean Journal of Obstetrics and Gynecology 2000;43(1):95-98
Spontaneous rupture of subcapsular liver hematoma in pregnancy is rare but potential life threatening complication of preeclampsia. We experienced a case of spontaneous rupture of subcapsular hematoma of liver that was treated with conservative method. So, we present the case with a brief review of literatures as first report in Korea.
Hematoma*
;
Korea
;
Liver*
;
Pre-Eclampsia
;
Pregnancy*
;
Rupture, Spontaneous
9.Association Between Executive Dysfunction-Related Activities of Daily Living Disability and Clinical Dementia Rating Domain Patterns in Patients With Vascular Dementia and Age-Matched Patients With Alzheimer’s Dementia
Byoung Sun JUN ; Kyung Min KIM ; Hyun Ju YANG ; Joon Hyuk PARK
Psychiatry Investigation 2023;20(12):1126-1132
Objective:
Although the Clinical Dementia Rating (CDR) scale was originally developed to stage Alzheimer’s dementia (AD), it is now used globally for various types of dementia. The aim of this study was to investigate the characteristic pattern of CDR domains and its association with neuropsychological findings and activities of daily living (ADL) in patients with vascular dementia (VaD) and patients with AD.
Methods:
We recruited very mild to mild VaD and AD patients who were age-matched among the first visitors to a dementia clinic. All subjects underwent a standardized clinical interview, physical and neurological examinations, and laboratory tests, including brain magnetic resonance imaging, according to the protocol of the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease assessment battery.
Results:
A total of 105 pairs of VaD and AD patients participated in this study. Although the adjusted scores on Korean version of the Mini-Mental State Examination were similar between the two groups, the VaD patients performed better on the Boston Naming Test, Word List Memory, Word List Recall, Word List Recognition, and Constructional Recall Test. However, the scores on global CDR, CDR sum of boxes, and ADL-related CDR domains were higher in VaD patients than in AD patients (p<0.001). The VaD patients also showed poor performances on the Disability Assessment for Dementia Scale, Frontal Assessment Battery, Executive Clock Drawing Task, and Stroop tests.
Conclusion
Despite similar general cognitive function and better memory function, patients with VaD tend to be staged as severer dementia on the CDR scale than patients with AD because of more impaired ADL associated with executive dysfunction.
10.Usefulness of Contralateral Indirect Decompression through Minimally Invasive Unilateral Transforaminal Lumbar Interbody Fusion.
Sang Hyuk MIN ; Jae Sung YOO ; Jun Yeul LEE
Asian Spine Journal 2014;8(4):453-461
STUDY DESIGN: Retrospective study. PURPOSE: This study aims to investigate the clinical and radiological results of contralateral indirect decompression through minimally invasive unilateral transforaminal lumbar interbody fusion (MI-TLIF). OVERVIEW OF LITERATURE: Several studies have proposed that blood loss and operation time could be reduced through a unilateral approach, although many surgeons have forecast that satisfactory foraminal decompression is difficult to achieve through a unilateral approach. METHODS: The study included 30 subjects who had undergone single-level MI-TLIF. Visual analogue scale (VAS) and Oswestry disability index (ODI) were analyzed for clinical assessment. Disc height, segmental lordosis, and lumbar lordosis angle were examined for radiological assessment. The degree of contralateral indirect decompression was evaluated through a comparative analysis, with a magnetic resonance imaging (MRI) performed preoperatively and at one year postoperatively. RESULTS: Intraoperative blood loss volume was 308.75 mL in the unilateral approach group (UAP), and 575.00 mL in the bilateral approach group (BAP), showing a statistically significant difference. Operation time was 139.50 minutes in the UAP group, and 189.00 minutes in the BAP group, exhibiting a statistically significant difference (p<0.05). On the other hand, no significant difference was found in VAS, ODI, disc height, lordosis angles and the degree of nerve decompression in the vertebral foramen, using MRI, between the two groups (p>0.05). CONCLUSIONS: Satisfactory results were acquired with MI-TLIF conducted through the unilateral approach of contralateral indirect decompression, in alignment with the bilateral approach. Therefore, contralateral indirect decompression is thought to be a useful procedure in reducing the operation time and volume of blood loss.
Animals
;
Decompression*
;
Hand
;
Lordosis
;
Magnetic Resonance Imaging
;
Retrospective Studies
;
Spinal Fusion
;
Surgical Procedures, Minimally Invasive