1.Changes of the cellularities in the bronchoalveolar lavage fluid of the experimental silicosis.
Young LIM ; Im Goung YUN ; Min Hwa OH
Tuberculosis and Respiratory Diseases 1991;38(2):14-154
No abstract available.
Bronchoalveolar Lavage Fluid*
;
Bronchoalveolar Lavage*
;
Silicosis*
2.An Epidemiological Study on the Selected Risk Factors of Hepatitis B Virus Infection.
Korean Journal of Preventive Medicine 1984;17(1):223-230
An attempt to confirm the associations of some selected risk factors of HBV infection and measure their risks, a cross-sectional study with 1,209 urban office workers was carried out. For the study, a simple questionnaire which contained several questions on personal experience and behaviors on several known selected risk factors of HBV infection was applied to each subject, and the Hepatitis B virus surface antigen and its antibody were checked by RPHA and PHA method, respectively. Risk factors chosen for this study were experience of blood transfusion and personal contact variables, such as frequencies of eating-out, drinking after office hours, going to tea room, sharing cigarettes, etc. The results obtained were as follows: 1. The proportion of HBsAg positive was 10.6%, and total HVB infected including the Anti-HBs positive cases without vaccination was 44.2%. Both were higher in male than in female. 2. Frequent personal contact through glasses and dishes in eating-outs and drinkings turned out not to be a significant risk factor of Hepatitis B surface antigenecity. 3. Frequent visits to tea room was a significant risk factor of HBV infection which combined HBsAg positive cases and Anti-HBs cases who had not received HBV vaccination. The odds ratio was 1.56. 4. Blood transfusion was not a significant risk factor of both HBsAg positive and total HBV infection. In summary, indirect oral contacts through eating-outs and drinkings was not significant risk factor in Korea at least between adults. Blood transfusion is no more mafor source of HBV infection in Korea probably because the adquate screening test of HBsAg for the blood donors is being made.
Adult
;
Antigens, Surface
;
Blood Donors
;
Blood Transfusion
;
Cross-Sectional Studies
;
Drinking
;
Epidemiologic Studies*
;
Eyeglasses
;
Female
;
Glass
;
Hepatitis B Surface Antigens
;
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
;
Humans
;
Korea
;
Male
;
Mass Screening
;
Odds Ratio
;
Surveys and Questionnaires
;
Risk Factors*
;
Tea
;
Tobacco Products
;
Vaccination
3.Comprehensive Predictors of Fatigue for Cancer Patients.
Young Min SEO ; Hyun Soo OH ; Wha Sook SEO ; Hwa Soon KIM
Journal of Korean Academy of Nursing 2006;36(7):1224-1231
PURPOSE: This study was conducted to identify comprehensive predictors of fatigue in cancer patients. METHODS: One hundred ten cancer patients visiting in-patient or out-patient clinics of a university hospital located in Incheon participated in this study. RESULTS: The hematologic indicators (WBC and Hemoglobin) were significant for explaining fatigue. The psychological factors of fatigue were statistically significant. Both anxiety and depression, included as psychological factors, were significant in explaining fatigue in cancer patients. The influence of physical factors on fatigue was also statistically significant. Among the variables included as physical factors, pain, nausea/vomiting/anorexia, and sleep disturbance were significant whereas, dyspnea was not significant. The influence of the daily activity factor on fatigue was statistically significant. Among the variables included as daily activity factors, regular exercise or not and the usual activity level were significant in explaining fatigue of cancer patients, while the level of rest was not statistically significant. CONCLUSIONS: From the study results fatigue of cancer patients appeared to be influenced by multidimensional factors, such as physiological, physical, psychological, and activity related factors.
Activities of Daily Living
;
Adaptation, Physiological
;
Adult
;
Aged
;
Fatigue/etiology/*nursing
;
Female
;
Health Status
;
Humans
;
Male
;
Middle Aged
;
Models, Nursing
;
Multivariate Analysis
;
Neoplasms/complications/*nursing
;
Sick Role
;
Sickness Impact Profile
4.Study on the Development of a Rapid Detection Method for Pathogenic Yersinia enterocolitica and Yersinia pseudotuberculosis by Nested Polymerase Chain Reaction.
Ho Jung OH ; Hong Ki MIN ; Yeo Won SOHN ; Seung Hwa HONG
Journal of the Korean Society for Microbiology 1999;34(2):175-187
A nested polymerase chain reaction (PCR) was applied to detect and identify pathogenic Yersinia enterocolitica and Y. pseudotuberculosis. We used photochemical postamplification procedure with 8-methoxypsoralen to control carryover contamination. Using the ail and inv gene, the sensitivity and specificity of DNA amplification by nested PCR was considerably improved. The amplified fragment sizes were 298 bp for the ail gene and 295 bp for the inv gene. Amplification was successful when the template was derived from three sources: purified DNA, aliquots of boiled bacterial suspension and aliquots of lysed bacterial suspension. The detection limits were 10 fg of DNA and 2 * 10 colony forming units (CFU) for Y. enterocolitica and 10 fg DNA and 2 CFU for Y. pseudotuberculosis.
DNA
;
Limit of Detection
;
Methoxsalen
;
Polymerase Chain Reaction*
;
Sensitivity and Specificity
;
Stem Cells
;
Yersinia enterocolitica*
;
Yersinia pseudotuberculosis*
;
Yersinia*
5.The Effect of Quinidine on Digoxin Clearance.
Ho Soon KIM ; Hyun Oh NA ; Wan Gyun SHIN ; Min Hwa LEE ; Jung Don SEO
Korean Circulation Journal 1994;24(3):482-485
BACKGROUND: Quinidine appeared to increase serum digoxin levels when given with quinidine. Therefore elevated serum digoxin concentrations and clinical toxicity have been reported in patient receiving quinidine. Currently, Bayesian method which estimates the most probable parameters of the drug for each patient from population parameters data is useful approach for adjusting digoxin dosage. To increase the accuracy of Bayesian method, it is desirable to use population parameters of Korean. Therefore we evaluated the effect of quinidine on digoxin clearance in Korea. METHOD: Patient's records from 19 adult cardiac disease without CHF having normal renal and liver function from Seoul National University of Hospital respectively wre evaluated. Digoxin pharmacokinetic parameters, CL and Vd, were obtained from serum concentration of digoxin of single and combined therapy at each steady-state by using bayesian method. RESULTS: This study show that quinidine reduced the total body clearance of digoxin from 2.39+/-0.17 to 1.51+/-0.08ml/min/kg(p<0.05) and reduced the digoxin volume of distribution from 8.57+/-0.29 to 4.98+/-0.19L/kg(p<0.05). This results show that digoxin dosage reduced to 40-50% in Korean, if quinidine therapy is initiated.
Adult
;
Bayes Theorem
;
Digoxin*
;
Drug Interactions
;
Heart Diseases
;
Humans
;
Korea
;
Liver
;
Pharmacokinetics
;
Quinidine*
;
Seoul
6.Maternal Cell Contamination in Chorionic Villus Sampling : An Analysis of Frequency in 1,059 Consecutive Cases.
Bo Hoon OH ; Jung Min LEE ; Gyung Hwa LEE ; Ae Young JUNG ; Moo Sik GWON
Korean Journal of Obstetrics and Gynecology 2000;43(8):1384-1388
No abstract available.
Chorion*
;
Chorionic Villi Sampling*
;
Chorionic Villi*
;
Female
;
Pregnancy
7.A case of pulmonary fibrosis after exposure to ammonia gas.
Hyeon Woo YIM ; Young LIM ; Im Goung YUN ; Min Hwa OH
Korean Journal of Occupational and Environmental Medicine 1991;3(2):227-234
No abstract available.
Ammonia*
;
Pulmonary Fibrosis*
9.Case of Follicular Bronchiolitis in Rheumatoid Arthritis.
Jong Hwa LEE ; MyungWoo CHOI ; Sung Sik OH ; Mi Rim CHOI ; Hyun Ju YANG ; Kwang Min LEE ; Kyoung Hwa CHOI
Journal of Rheumatic Diseases 2016;23(6):392-395
Follicular bronchiolitis is an uncommon bronchiolar disorder that is characterized by the presence of hyperplastic lymphoid follicles with reactive germinal centers. The condition is associated with connective tissue diseases such as rheumatoid arthritis, Sjögren’s syndrome, and immunodeficiency disorders. A 56-year-old man with rheumatoid arthritis was admitted to hospital with a progressively enlarging pulmonary nodule in the left upper lobe. A follow-up contrast tomography scan showed that the nodule had increased in size from 4.2 mm to 6.3 mm over a 3 month period. An open lung biopsy was performed to establish a definite pathologic diagnosis of the pulmonary nodule, which was suspected to be a lung malignancy. The nodule was diagnosed as follicular bronchiolitis based on the histopathology findings. We describe a patient with follicular bronchiolitis that was confirmed by an open lung biopsy, and is believed to have had rheumatoid involvement.
Arthritis, Rheumatoid*
;
Biopsy
;
Bronchiolitis*
;
Connective Tissue Diseases
;
Diagnosis
;
Follow-Up Studies
;
Germinal Center
;
Humans
;
Lung
;
Middle Aged
;
Solitary Pulmonary Nodule
10.The Effect of Hydroxyl Radical Generation on the Cytotoxicity of Alveolar Macrophage and Lipid Peroxidation of Erythrocyte Membrane by Mineral Fibers.
Kyoung Ah KIM ; Young LIM ; Ji Hong KIM ; Hwang Sin CHANG ; Chung Yill PARK ; Im Goung YUN ; Min Hwa OH
Korean Journal of Occupational and Environmental Medicine 1997;9(3):401-410
No abstract available.
Erythrocyte Membrane*
;
Erythrocytes*
;
Hydroxyl Radical*
;
Lipid Peroxidation*
;
Macrophages, Alveolar*
;
Mineral Fibers*