Livedoid vasculitis is characterized clinically by smooth or depressed ivory-white scars surrounded by hyperpigmentation and telangiectasia with or without preceding purpuric in-filtrated papules and plaques and histologically by intravascular deposition of fibrin. Its pathophysiology is still obscure. Many treatment modalities have been used, but results are not satisfactory. Recently, there have been experiences of successful treatments with danazol, a synthetic androgen. We used danazol in three patients who presented with livedoid vasculitis and were relatively resistant to treatments with aspirin and/or pentoxifylline. After 4 to 8 weeks, there was remarkable clinical improvement in all three patients.
Aspirin ; Cicatrix ; Danazol* ; Fibrin ; Humans ; Hyperpigmentation ; Pentoxifylline ; Telangiectasis ; Vasculitis*

Aneurysm of the pulmonary artery is a rate entity. A neonate was seen with cyanosis and tachypnea. There was a grade 4/6 systolic murmur along the left sternal border. The chest X-ray showed a round mass shadow in the left parahilar region. Echocardiogram showed large Ventricular Septal Defect and mild Pulmonary Stenosis. The cardiac angiogram showed giant aneurysm of pulmonary artery. Surgical intervention was advised. However, the patient was discharged against operative plan. And the patient died two weeks later.
Aneurysm* ; Cyanosis ; Heart Septal Defects, Ventricular* ; Humans ; Infant, Newborn ; Pulmonary Artery ; Pulmonary Valve Stenosis* ; Systolic Murmurs ; Tachypnea ; Thorax

Trichilemmal carcinoma is a rare malignant neoplasm of the hair follicle, which is derived from or differentiates towards cells of the outer root sheath. We report a case of trichilemmal carcinoma in an 83-year-old female patient. She presented with a tender dome-shaped crusted papule showing a feature of cutaneous horn on the forehead, which was first detected 6 months before. nstopathologically, lobular patterned tumor cells with peripheral palisade of basaloid cells, nuclear atypia, and clear or pale, PAS-positive, diastase-sensitive cytoplasm were observed beneath the marked hyperkeratosis. After the diagnosis, total excision was done. The patient has been free of recurrence or metastasis till now.
Aged, 80 and over ; Animals ; Cytoplasm ; Diagnosis ; Female ; Forehead ; Hair Follicle ; Horns* ; Humans ; Neoplasm Metastasis ; Recurrence

PURPOSE: Persistent pulmonary hypertension (PPHN) is considered an important prognostic factor in meconium aspiration syndrome (MAS). The aim of this study was to determine the comorbid risk factors for PPHN in infants with MAS. METHODS: We retrospectively analyzed 60 infants diagnosed with MAS and admitted to the neonatal intensive care unit of the Sanggye Paik Hospital from January 2007 to April 2013. There were 28 infants (47%) with PPHN and 32 infants (53%) without PPHN. Clinical characteristics, laboratory findings within 24 hours after birth, and initial capillary blood gas analysis results were compared between infants with and without PPHN. RESULTS: Incidence of PPHN was associated with the severity of MAS (P<0.001). The PPHN group had a greater incidence of hypotension and hypoxic-ischemic encephalopathy within 24 hours of birth compared to the non-PPHN group. The PPHN group also had a lower initial pH. However, there was no significant difference for laboratory findings within 24 hours of birth and initial capillary blood gas analysis. In the multivariate analysis, hypotension within 24 hours of birth (P=0.046, odds ratio 11.494, 95% confidence interval 1.048-125.00) was found to be a significant comorbid factor for PPHN in infants with MAS. CONCLUSION: Infants with MAS who develop hypotension within 24 hours of birth should be closely monitored for development of PPHN.
Blood Gas Analysis ; Capillaries ; Humans ; Hydrogen-Ion Concentration ; Hypertension, Pulmonary* ; Hypotension ; Hypoxia-Ischemia, Brain ; Incidence ; Infant* ; Infant, Newborn* ; Intensive Care, Neonatal ; Meconium Aspiration Syndrome* ; Multivariate Analysis ; Odds Ratio ; Parturition ; Retrospective Studies ; Risk Factors*

More than half of patients presenting with hoarseness show benign vocal cord changes. However, in rare cases with benign mucosal lesions, it can be diagnosed as a malignant disease after histopathological examination. A 53-year-old man with a 30-pack-year smoking history was admitted for the evaluation of hoarseness, and using a laryngoscope, an enclosed, sac-like cystic lesion was detected on the midpoint of the right true vocal cord. The cystic lesion was deemed to be an intracordal cyst and treated with laryngeal microsurgery. However, pathological findings showed squamous cell carcinoma of the larynx arising in the intracordal cyst, which is exceptionally rare. Therefore, even if a benign lesion is initially suspected, a biopsy must be performed on a patient with smoking history to confirm the diagnosis. In conclusion, we report a case of squamous cell carcinoma of the larynx arising in the intracordal cyst.

More than half of patients presenting with hoarseness show benign vocal cord changes. However, in rare cases with benign mucosal lesions, it can be diagnosed as a malignant disease after histopathological examination. A 53-year-old man with a 30-pack-year smoking history was admitted for the evaluation of hoarseness, and using a laryngoscope, an enclosed, sac-like cystic lesion was detected on the midpoint of the right true vocal cord. The cystic lesion was deemed to be an intracordal cyst and treated with laryngeal microsurgery. However, pathological findings showed squamous cell carcinoma of the larynx arising in the intracordal cyst, which is exceptionally rare. Therefore, even if a benign lesion is initially suspected, a biopsy must be performed on a patient with smoking history to confirm the diagnosis. In conclusion, we report a case of squamous cell carcinoma of the larynx arising in the intracordal cyst.

Apocrine gland carcinoma is a rare form of sweat gland neoplasm. Although the region of the axilla remains the most common site for these tumors, apocrine gland carcinomas of the other regions have been reported. This is a tumor of adults with no evident prevalence for sex and race. Most patients have a history of a long-standing neoplasm before the diagnosis is made and a favorable outcome. A 33-year-old man showed an axillary nodule with regional lymph node enlargement. Histopathologic examination revealed a poorly differentiated adenocarcinoma. The tumor was positive in immunohistochemical staining with CEA and BRST-2.
Adenocarcinoma ; Adult ; Apocrine Glands* ; Axilla* ; Continental Population Groups ; Diagnosis ; Humans ; Lymph Nodes ; Prevalence ; Sweat Gland Neoplasms

Leiomyoma cutis is a benign tumor originating from smooth-muscle fibers. It arises from the arrectores pilorum muscles of the skin, the lamina media of subcutaneous blood vessels, or dartoic muscle of the genital regions and nipples. Leiomyoma of the nipple is the less frequent type of cutaneous leiomyoma. We report a case of leiomyoma cutis on the nipple in a 40-year-old woman. She presented with asymptomatic macule on the nipple. On histopathologic examination, interlacing bundles of smooth muscle fibers were seen in the dermis.
Adult ; Blood Vessels ; Dermis ; Female ; Humans ; Leiomyoma* ; Muscle, Smooth ; Muscles ; Nipples* ; Skin

Generalized syringoma is a rare variant of syringoma. In generalized syringoma, numerous papules arise in successive crops on the anterior surface of the body involving the chest, neck, and abdomen. It usually occurs in adolescents and young adults. Males and females are almost equally affected. A 19-year-old man presented with multiple 2-3mm sized papules on the chest, abdomen, and upper back. There was no subjective symptom. Family history showed that his mother had similar lesions. Histopathologic examination showed numerous eccrine ducts of various shapes and sizes lined by a double layer of squamous epithelium. Herein, we present a case of generalized syringoma with a review of the literature.
Abdomen ; Adolescent ; Epithelium ; Female ; Humans ; Male ; Mothers ; Neck ; Syringoma* ; Thorax ; Young Adult

Acute mesenteric ischemia is a state in which intestinal infarction can be caused by a sudden decrease in blood flow. A 68-year-old man was transferred to Hanyang University Guri hospital with abdominal pain. A computed tomography scan performed before the transfer showed no abnormal findings. Examination and evaluation revealed abnormal electrocardiogram findings and increased troponin I. Although emergency coronary angiography was normal, the patient continued to complain of severe abdominal pain. A computed tomography scan showed occlusion of the superior mesenteric artery. Percutaneous aspiration embolectomy was successfully performed prior to surgery, and subsequent laparoscopic exploration revealed an area of bowel necrosis which was then resected. The length of the small intestine remaining after resection measured 1.6 m. On postoperative Day 6, the patient began a soft food diet and was prescribed medication after being diagnosed with atrial fibrillation. He was discharged on the 13th postoperative day without postoperative complications.