No abstract available.
Atrophy ; Pityriasis* ; Tinea Versicolor*

Acne fulminans (AF) is a rare severe form of acne associated with systemic symptoms. It primarily affects male adolescents and is clinically characterized by painful ulcerative nodules on the face, chest, and back. The associated systemic symptoms, such as fever, myalgia, and arthralgia, are usually present at the onset. The etiology of AF remains unknown, but there are many theories, such as increased androgens, autoimmune complex disease, and genetic predisposition. Treatment can be challenging because its response to traditional acne therapies is poor. A combination of oral steroids and isotretinoin is the most recommended treatment. Herein, we report a case of a 16-year-old Korean man with acne fulminans presenting with tender, hemorrhagic, crusted, inflammatory nodules on the upper chest, which occurred after isotretinoin use. After treatment with oral isotretinoin and pulsed dye laser for 23 weeks, most of the lesions healed leaving some scars.
Acne Vulgaris* ; Adolescent ; Androgens ; Arthralgia ; Cicatrix ; Fever ; Genetic Predisposition to Disease ; Humans ; Isotretinoin* ; Lasers, Dye ; Myalgia ; Steroids ; Thorax ; Ulcer

BACKGROUND: Androgenetic alopecia (AGA) is the most common type of hair loss, and androgens and genetic predisposition are believed to be the major factors that influence the development of AGA. Although there have been previous reports about the relationship between family history, smoking and insulin resistance with AGA, no previous study has investigated lifestyle habits such as eating habits in AGA patients. OBJECTIVE: The aim of this study was to investigate family history, lifestyle including smoking and eating habits in AGA patients and to compare the results with data from Korea Health Statistics 2009: Korea National Health and Nutrition Examination Survey (KNHANESIV-3). METHODS: We retrospectively evaluated a total of 347 male patients with AGA who visited the Department of dermatology, Inha University School of medicine, from September 2010 to August 2012. RESULTS: AGA with paternal family history was the most common (49.9%), and both of maternal and paternal family history was the least (10.1%). Body mass index and smoking did not show significant differences but eating habits showed a statistically significant difference according to the duration of AGA. Patients with longer disease duration (> or =60 months) showed higher intake of meat but low intake of fish than those with shorter disease duration (<12 months). Also, AGA patients showed low intake of beef, bean and squid in comparison to the average Korean population. CONCLUSION: This was the first study which investigated lifestyle habits such as eating habits in AGA patients and compared the results with data from Korea Health Statistics. However, a further large scale Cohort study is needed to define the casual relationship between eating habits and the development of AGA. Also, a further study including the difference of serum and hair androgen levels in relation to different lifestyle habits should be done.
Alopecia* ; Androgens ; Body Mass Index ; Cohort Studies ; Decapodiformes ; Dermatology ; Eating ; Genetic Predisposition to Disease ; Hair ; Humans ; Insulin Resistance ; Korea ; Life Style* ; Male ; Meat ; Nutrition Surveys ; Retrospective Studies ; Smoke ; Smoking

No abstract available.
Female ; Humans

Myoepitheliomas of salivary gland occur infrequently and are generally benign. Malignant myoepitheliomas of salivary gland are extremely rare tumor, and increasing number of case reports have shown that malignant myoepitheliomas may either arise de novo or develop in a pre-existing pleomorphic adenoma. In our case, myoepitheliomas was located in the parotid gland, and tumor cells displayed morphological features of spindle & epithelioid cells. Their clinical behavior by literature seems variable. This case dealt with malignant myoepithelioma of the parotid gland in a 65-year-old man with a relatively favourable course, and was followed up for 2 years and 5 months. In addition, this case illustrates some of the characteristic clinical and pathological features of this rare tumor.
Adenoma, Pleomorphic ; Aged ; Epithelioid Cells ; Humans ; Myoepithelioma* ; Parotid Gland* ; Salivary Glands

BACKGROUND: Smoking is one of the most important leading causes of morbidity and mortality. Smoking habit is recognized as nicotine dependence, which consists of physical and psychosocial dependence. To evaluate social nicotine dependence, the Kano Test for Social Nicotine Dependence (KTSND) working group developed a new questionnaire, which consists of 10 questions with a total score of 30 in Japan. We examined the social nicotine dependence among healthy adults using the new KTSND questionnaire and evaluated validity of the KTSND questionnaire in Korea. METHOD: We applied Korean KTSND questionnaire version 2 to employees of hospital, university students and people for medical examination and promotion test. Complete data obtained from the 741 responders were analyzed. RESULT: The mean age of responders was 31.8 years. Among them, males were 57.8%. Current smokers, ex-smokers, and non-smokers were 13.8%, 12.8%, and 73.4% respectively. According to smoking status, the total KTSND scores of current smokers were significantly higher than those of ex-smokers, and of non-smokers (17.1+/-5.4 versus 14.3+/-5.5, and 12.3+/-5.5, p< or =0.001). The total KTSND scores of males were higher than those of females, suggesting that males have a propensity for depending nicotine socially much more than females (14.3+/-5.7 and 11.7+/-5.4 respectively, p<0.001). Eight of ten questions produced significantly different scores among three different smoking groups. When current smokers were sub-classified by heavy smoking index (HSI) that represented physical nicotine dependence, we did not find a significant difference of KTSND score between low HSI group (<4) and high HSI group (> or =4), This finding suggested that the psychosocial dependence might play a different role from physical nicotine dependence in smoking. Most of the non-smokers (62.5%) had an experience of harmful passive smoking especially in public place. CONCLUSION: Our study suggested that the KTSND questionnaire could be a useful method to evaluate psychosocial aspects of smoking.
Adult ; Female ; Humans ; Japan ; Korea* ; Male ; Mortality ; Nicotine* ; Surveys and Questionnaires* ; Smoke ; Smoking ; Tobacco Smoke Pollution ; Tobacco Use Disorder*

Lichen Planus Pigmentosus (LPP), an uncommon variant of lichen planus, is clinically characterized by insidious onset of diffuse or reticulated hyperpigmented patches on the sun-exposed areas and flexural folds. Histopathologic findings of LPP show atrophic epidermis with vacuolar degeneration of the basal cell layer and sparse lichenoid lymphohistiocytic infiltration with melanophages in the dermis. Although there have been few reports of LPP, clinical and histological pathogenesis and prognosis are not well known. Herein, we describe a case of linear LPP along the Blaschko's lines in 34-year old Korean man who presented with linear hyperpigmented, dark brown patches on his left thigh, repeatedly developing new lesions of erythematous reticular patches since puberty. This report shows the early events of LPP and the protracted course.
Dermis ; Epidermis ; Lichen Planus ; Lichens ; Prognosis ; Puberty ; Thigh

Localized Darier's disease (DD) is a rare variant of DD. The disease is characterized by multiple hyperkeratotic papules in a unilateral, linear, zosteriform or Blaschkoid distribution with the histological features of classical DD. Unlike DD, which presents as a generalized condition, localized DD lacks family history and other clinical findings suggestive of DD such as distinctive nail abnormalities and keratotic papules on the palms and soles. Herein, we describe a case of localized DD in a 31-year old Korean man on the perianal area that was treated with topical retinoid cream.
Darier Disease* ; Humans ; Nails, Malformed

Follicular mycosis fungoides is a distinct variant of mycosis fungoides. Clinically, it occurs mostly in adults, affecting more males than females. It is manifested as pruritic follicular papules, acneiform lesions, or indurated plaques, typically in the head and neck. Histopathologically, it is characterized by infiltration of atypical T lymphocytes with cerebriform nuclei in the follicular epithelium (folliculotropism). We report a case of follicular mycosis fungoides manifested as a milia-like lesion combined with the patch stage of mycosis fungoides, which was treated with radiotherapy.
Adult ; Epithelium ; Female ; Head ; Humans ; Male ; Mycosis Fungoides* ; Neck ; Radiotherapy ; T-Lymphocytes

No abstract available.
Alopecia ; Minoxidil