1.Studies on the bfp Gene, Adherence to HEp-2 Cells and Serotyping of Escherichia coli Isolated from Urine.
Yung Bu KIM ; Min Jung KIM ; Geun Sam PARK
Journal of the Korean Society for Microbiology 1998;33(1):77-87
Eighty-two strains of Escherichia coli isolated from urine specimens in Pusan University Hospital, were serotyped and analyzed for plasmid DNA profiles, PFGE profiles, MRHA of human blood cells, HEp-2 cell adherence ability and reactivity to bfpA, LT, STh and STp DNA probes. The following results were obtained. Fifty-three of the eighty-two strains belonged to thirteen different 0 serotypes, twenty-nine strains could not be typed with the antisera used. Thirty strains (43.9%) were hemolysin producer. MRHA is present on twenty-nine strains (35.37%) of eighty-two strains. MRHA positive strains carry a plasmid of 60MDa, a putative factor involved in adherence. This plasmid might be specific for MRHA positive strains. MRHA positive strains were observed in serotype 01, 018, 055, 086a, 0119, 0126, and 0142. Twenty-six strains of E. coli showed three patterns of adherence to HEp-2 cells namely, localized, diffuse, and aggregative adhesion. Twenty-two strains hybridized with the bfpA probe, while all eighty-two strains did not hybridize with the probes, LT, STh, STp. The restriction fragment patterns of chromosomal DNA digested with AotI analysed by PFGE of hemolysin-producing E. coli ten strains were compared with eight different types. Three of E. coli serotype 01, 08 and 0126 showed the same chromosomal DNA fragment patterns.
Blood Cells
;
Busan
;
DNA
;
DNA Probes
;
Escherichia coli*
;
Escherichia*
;
Humans
;
Immune Sera
;
Plasmids
;
Serotyping*
2.Evaluation of Simple Tool as a Screening Test for Osteoporosis and Osteopenia in Korean Postmenopausal Women .
Hye Joon PARK ; Kyung Hee PARK ; Geun Min PARK ; Yoo Jin PAEK ; Jung Jin CHO
Journal of the Korean Academy of Family Medicine 2003;24(8):702-708
BACKGROUND: Osteoporosis is an important health concern among the postmenopausal women. Therefore, it is necessary to find out acceptable screening tools for osteoporotic patients. The purpose of this study was to evaluate the Risk Index by OSTA as a screening test for osteoporosis. METHODS: The study population was 322 naturally caused menopausal women in Korea. Their was of femoral neck and lumbar spine BMD measured by DEXA. Risk Index by OSTA, based on weight and age, was calculated and the sensitivity and specificity for osteoporosis and osteopenia were evaluated. To find out the proper cut-off point for osteoporosis and osteopenia among the postmenopausal women in Korea, we also compared the sensitivity and specificity of each Risk Index value. RESULTS: The mean age and ages at menopause were 59.1(+/-6.2) and 50.7 (+/-2.7) years, respectively. The prevalence of osteoporosis was 9.6% with femoral neck BMD. For oeteoporosis, using a cut-off point of -1 yielded a sensitivity of 74.3% and a specificity of 52.2% with femoral neck BMD. Using a cut-off of -2 yielded a sensitivity of 87.3% and a specificity of 70.9%. The ROC curve showed an AUROC 0.88 for Risk Index in identifying osteoporosis. CONCLUSION: The Risk Index is an acceptable, simple and useful method in the diagnosis of osteoporosis with a Risk Index of -2 in Korean postmenopausal women.
Bone Diseases, Metabolic*
;
Diagnosis
;
Female
;
Femur Neck
;
Humans
;
Korea
;
Mass Screening*
;
Menopause
;
Osteoporosis*
;
Prevalence
;
ROC Curve
;
Sensitivity and Specificity
;
Spine
3.A Case of Malignant Acanthosis Nigricans Associated with Gastric Adenocarcinoma.
Hyung Geun PARK ; Seong Min PARK ; Doo Chan MOON ; Kyung Sool KWON ; Tae Ahn CHUNG
Korean Journal of Dermatology 1989;27(3):316-319
A 51-year-old female had disseminated, symmetrically distributed, brownish black pigmentation and papillary hypertrophy on the intertriginous and flexural areas for 6 months, and gastric adenocarcinoma was confirmed during the evaluation of internal malignancy, The cutaneous finding of acanthosis nigricans was a significant cutaneous marker of internal malignancy in this case.
Acanthosis Nigricans*
;
Adenocarcinoma*
;
Female
;
Humans
;
Hypertrophy
;
Middle Aged
;
Pigmentation
4.Effects of Alginate Culture on Viability, Proliferation, and Phenotype of Canine Articular Chondrocytes.
Hyeong Geun PARK ; Jeong Im WOO ; So Ra PARK ; Han Jo LIM ; Byoung Hyun MIN
Journal of Korean Orthopaedic Research Society 2001;4(1):24-31
No Abstract Available.
Chondrocytes*
;
Phenotype*
5.Acute appendicitis in children.
Min Hang KIM ; Tae Geun SONG ; Jae Sun PARK ; Chung Han LEE
Journal of the Korean Pediatric Society 1992;35(1):51-59
No abstract available.
Appendicitis*
;
Child*
;
Humans
6.Factors Associated with the Direction of Ocular Deviation in Sensory Horizontal Strabismus and Unilateral Organic Ocular Problems.
In Geun KIM ; Jung Min PARK ; Soo Jung LEE
Korean Journal of Ophthalmology 2012;26(3):199-202
PURPOSE: To evaluate factors associated with the direction of horizontal deviation in the sensory strabismus of patients with unilateral organic amblyopia. METHODS: The medical charts of 53 patients who had been diagnosed with sensory strabismus between 2000 and 2009 were reviewed retrospectively. The underlying ocular disease, time of onset and the duration of vision impairment, refractive error and axial length of the fixing eye, and the direction and angle of deviation were analyzed to determine the distribution of underlying diseases and any factors relevant to determining the direction of the horizontal deviation. RESULTS: Congenital cataracts were the most common underlying disease, found in 33 patients, followed by acquired cataracts, optic nerve disorders, retinal detachment, glaucoma and lens subluxation. Among the 50 patients with horizontal strabismus, 11 had esotropia and 39 had exotropia. The incidence of esotropia was significantly higher when the fixing eye had hyperopia or emmetropia, than when the eye was myopic. Age of onset of vision deterioration and at diagnosis of sensory strabismus, and the axial length of the fixing eye had no relationship to the direction of horizontal deviation. In addition, the duration of visual impairment had no significant relationship with the direction or extent of horizontal deviation. CONCLUSIONS: The most common cause of sensory strabismus was congenital cataracts and the most frequent type of strabismus was exotropia. With respect to the direction of horizontal strabismus, esotropia occurred significantly more often when the refractive error of the fixing eye was hyperopia or emmetropia than when the fixing eye was myopic.
Adolescent
;
Adult
;
Amblyopia/*complications/physiopathology
;
Cataract/complications/congenital/physiopathology
;
Child
;
Child, Preschool
;
Eye Movements/*physiology
;
Female
;
Follow-Up Studies
;
Humans
;
Infant
;
Infant, Newborn
;
Male
;
Oculomotor Muscles/*physiopathology
;
Refractive Errors
;
Retrospective Studies
;
Risk Factors
;
Strabismus/etiology/*physiopathology
;
Visual Acuity
;
Young Adult
7.A Case of Protein Energy Malnutrition After Whipples' s Operation.
Min Ah PARK ; Sang Geun HA ; Young Ho WON ; Inn Ki CHUN
Korean Journal of Dermatology 1994;32(1):130-133
Protein energy malnutrition occurs when inadequate protein and calories are ingested. PEM is not confined to children and is common in hospitalized patients. PEM is diagnosed by a weight loss and hypoalbuminemia. We report a case of PEM in a 27-year-old man after Whipple's operation. He had brittle hair, loss on the scalp and brownish colored papules with desquamation on extremities. Also he had erosion and fissuring on the perioral area and beef tongue. Treatment with zinc sulfate, albumin and vitamin resulted in a good response.
Adult
;
Child
;
Extremities
;
Hair
;
Humans
;
Hypoalbuminemia
;
Protein-Energy Malnutrition*
;
Scalp
;
Tongue
;
Vitamins
;
Weight Loss
;
Zinc Sulfate
8.Comparison of the 20-Gauge Conventional Vitrectomy Technique with the 23-Gauge Releasable Suture Vitrectomy Technique.
In Geun KIM ; Soo Jung LEE ; Jung Min PARK
Korean Journal of Ophthalmology 2013;27(1):12-18
PURPOSE: To compare the efficacy of the transconjunctival releasable suture technique for pars plana vitrectomy using 23-gauge (23G) instruments versus the conventional 20-gauge (20G) technique. METHODS: A retrospective and interventional case series was consecutively performed for 199 eyes of the 192 patients that were a part of this study. Clinical data were reviewed retrospectively regarding the operation time, preoperative and postoperative intraocular pressure, visual acuity and astigmatism for 54 consecutive patients who received a 23G releasable suture vitrectomy and for 98 consecutive patients who received a 20G conventional vitrectomy during the period between April 2007 and September 2010. RESULTS: Mean operation time based on the operation record was 88.5 +/- 20.1 minutes in the 23G releasable suture vitrectomy group and 102.1 +/- 23.1 minutes in the 20G conventional vitrectomy group, respectively (p = 0.01). The last best-corrected visual acuity (BCVA) was significantly better than the preoperative BCVA in both patient groups (p = 0.01, p = 0.01). The 23G releasable suture group showed less surgically induced astigmatism than the 20G conventional vitrectomy group. Vitreous bleeding was observed to be in 6 eyes (5.9%) in the 23G group, and in 8 eyes (8.2%) in the 20G group. In addition, ocular hypertension was noted to be in 3 eyes (3.0%) in the 23G group, and 6 eyes (6.1%) in the 20G group. No serious complications such as postoperative hypotony or endophthalmitis were observed in either group. CONCLUSIONS: The 23G releasable suture technique is as effective as the 20G conventional technique and offers several advantages.
Adult
;
Aged
;
Equipment Design
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Middle Aged
;
Retrospective Studies
;
Suture Techniques/*instrumentation
;
*Sutures
;
Treatment Outcome
;
Visual Acuity
;
Vitrectomy/*methods
;
Vitreous Hemorrhage/physiopathology/*surgery
9.Maxilla reconstruction with free flap after total maxillectomy.
Jeong Il PARK ; Tae Geun HAN ; Joon CHOE ; Se Min BAEK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(1):39-46
No abstract available.
Free Tissue Flaps*
;
Maxilla*
10.Effect of Topical Bromfenac as a Treatment of Cystoid Macular Edema Following Pars Plana Vitrectomy
Cheol-Won MOON ; Dong-Geun PARK ; Min SAGONG
Journal of the Korean Ophthalmological Society 2020;61(12):1467-1476
Purpose:
To investigate the functional and anatomical effectiveness of bromfenac sodium hydrate ophthalmic solution for the treatment of cystoid macular edema (CME) after pars plana vitrectomy (PPV).
Methods:
A retrospective chart review of 53 patients was performed. Thirty-seven eyes received topical 0.1% bromfenac sodium hydrate ophthalmic solution (nonsteroidal anti-inflammatory drug [NSAID] group), and 16 eyes were treated with subtenon triamcinolone acetonide injection (injection group). Of the NSAID group, 27 eyes underwent PPV with cataract surgery, and 10 eyes underwent PPV without cataract surgery. Best-corrected visual acuity (BCVA), central macular thickness (CMT), and intraocular pressure (IOP) were measured at baseline and monthly after treatment initiation over a 6-month period.
Results:
No significant difference in mean BCVA from baseline was found for either group over the 6-month follow-up. The injection group showed significantly greater improvement in CMT than the NSAID group at 4 months; however, there was no significant difference between the two groups at the 5-month follow-up visit. IOP was significantly higher in the injection group (p = 0.035 at 2 months), but not in the NSAID group. In the NSAID group, neither PPV group, with and without cataract surgery, showed any significant difference in mean BCVA from baseline over the 6 months of follow-up. The baseline CMT was significantly greater in the PPV with cataract surgery group than in the PPV without cataract surgery group (p = 0.023). However, at the 1-month follow-up, no significant difference in mean CMT from baseline values was observed in either group over the remaining follow-up examinations, up to 6 months.
Conclusions
Topical bromfenac resulted in an improvement in the BCVA and a reduction in the CMT, with a less adverse effect in the treatment of CME after PPV, regardless of whether cataract surgery was performed at the same time.