Research on dual-use of life sciences can promote human health and social development .However,potential harm is also gradually recognized .This article introduces the definition of dual-use life sciences research , major develop-ments and risk samples , trends of development and surveillance , and proposes some considerations in future efforts to strengthen the oversight of dual-use life sciences research .

Due to the large population and relatively closed space environment , the subway system is vulnerable to bioterrorist attacks.This paper analyzes the technological response measures against subway bioterrorism in the United States, including Detect to Protect program of Department of Homeland Security (DHS) and PROTECTS program of Depart-ment of Energy ( DOE) .We also put forward some proposals on how to improve China′s capability of prevention of and response to subway bioterrorism .

Biosecurity is defined as effectively responding to biological damage associated with various destructive fac -tors and threats ,maintaining and protecting national interests ,security and public health in the era of globalization .This pa-per analyzes the overall situation of biosecurity capability building since the SARS outbreak in 2003 before concluding that remarkable progress has been made in China , but the gap remains great compared with the need of national security envi -ronment and the capacity building of developed countries .This paper outlines four considcrations regarding the development of biosecurity research strategic planning and offer eight tips on strengthening research on biosecurity technology in China .

Biosecurity is an important component of national security and an important guarantee for national revival and the realization of China's dream.However China is facing increasingly serious biological threats .Biosecurity capability build-ing has some problem .For exanyple ,people have a vague idea about the relationship between different biological threats ,the duties and rights of civil-military integration development , the balance between sustainable development and emergency pre-vention and control capacity-building, multidisciplinary convergence of biosecurity capacity-building, and about ways to break down the technological blockade and market monopoly by the United States and other developed countries .

The 2013 Meeting of Experts from States Parties to the Biological Weapons Convention ( BWC) was held in Geneva from August 12 to 16 in 2013 .This paper reviews the main topics and results of the meeting , analyzes the current situation of biological arms control , and proposes some methods to strengthen implementation .

Classification of biological agents is a basic work in biodefense capability building that can help set priorities of biodefense .In this study , we compared and analyzed the Biological Agent Category Lists and the defining criteria used by the Center for Disease Control and Prevention ( CDC) of the United States, the European Union and Russia .We also compared with biological agent category lists for other purposes .

The biological threat is an important component of national security threats .Developed countries attach great importance to biodefense capability building .This paper analyzed the particularity of biological threats , explained the necessi-ty of biosecurity strategic research and development in China , and proposed establishing an integrated biodefense system .

Computational epidemiology is a fast-developing and interdisciplinary research area .Through comprehensive computation-analysis of multi-uncertain factors affecting the epidemic process , this method may add to our knowledge about epidemic patterns and help design reasonable response plans and emergency strategies .This article briefly summarizes the idea and theory of computational epidemiology based on related researches in the recent years , introduces the application of this method in case of smallpox bioterrorism and influenza pandemic , and predicts the development of this area .

The use of the Internet big data to discriminate the early symptoms of unexpected biological events has be-come a frontier research area in biosurveillance .This paper mainly introduces the principle , method, practical applications of big data based biosurveillance , and the future development of this new research field .

Biodefense research based on modern information technology is an important supplement to traditional biode -fense capacity building and an important part of the national biodefense system in the 21st century.This article outlines the typical biodefense information systems developed in the last ten years and analyzes the development trends of this research field.It is hoped that more domestic research institutions or researchers can become interested in this field .