1.Depression, suicide, and Korean society.
Mihee NAM ; Dae Seog HEO ; Tae Yeon JUN ; Min Soo LEE ; Maeng Je CHO ; Changsu HAN ; Min Kyung KIM
Journal of the Korean Medical Association 2011;54(4):358-361
The number of Korean people who are currently suffering from depressive disorders that require medical treatment is assumed to be more than 2 million. However, only around 15% of those with depressive disorder are actively receiving medical treatment, and this leads to an increasing suicide rate. Hence, the National Evidence-based Healthcare Collaborating Agency held a round-table conference to provide information on depression and suicide and suggested a reasonable policy through comprehensive discussion with experts. The prevalence of depression, which is closely related to suicide rates, is lower in Korea than in the U.S., but the rate of suicide is the highest among Organisation for Economic Co-operation and Development countries. It is thought that the underestimated prevalence of depression is owing to the inconsistency between the diagnostic criteria of depression and characteristics of depression in Korea. Therefore, it is necessary to develop Korean diagnostic criteria for depression reflecting cultural characteristics and conduct a regular and organized nationwide survey. Moreover, a term related to suicide officially used by Statistics Korea is 'intentional self-injury'. However, in a Korea-based community study, it was found that 60% to 72% of those attempting suicide had mental disorders; thus suicide is not merely an intentional self-injury but a medical condition that should be treated. To reduce suicide, both medical and social approaches are necessary. Furthermore, a strengthening of the public perception that a medical approach is important for suicide prevention is greatly needed. Moreover, it is necessary to prepare an effective national suicide prevention strategy through studies evaluating the suicide prevention policies currently implemented and psychological autopsy of suicide deaths similar to those practiced in Finland.
Autopsy
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Cultural Characteristics
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Delivery of Health Care
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Depression
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Depressive Disorder
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Finland
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Korea
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Prevalence
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Stress, Psychological
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Suicide
2.Wood Decay Fungi in South Korea: Polypores from Seoul.
Yeongseon JANG ; Seokyoon JANG ; Jaejung LEE ; Hwanhwi LEE ; Hanbyul LEE ; Young Min LEE ; Joo Hyun HONG ; Mihee MIN ; Young Woon LIM ; Changmu KIM ; Jae Jin KIM
Mycobiology 2014;42(2):140-146
In Seoul, a majority of plant communities have undergone significant changes over the last few decades; however, how wood decay fungi have responded and adapted to the changes in vegetation remains unknown. Through an ongoing investigation of Korean indigenous fungi, ca. 300 specimens with poroid basidiocarp were collected in Seoul during 2008~2012. Morphological examination and molecular analysis using the internal transcribed spacer and nuclear large subunit ribosomal DNA region sequences helped identify 38 species belonging to 28 genera, 10 families, and 5 orders in this area. Among them, three polypores, Abundisporus pubertatis, Coriolopsis strumosa, and Perenniporia maackiae were found to be new to South Korea.
Basidiomycota
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Classification
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DNA, Ribosomal
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Fruiting Bodies, Fungal
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Fungi*
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Humans
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Korea
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Maackia
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Phylogeny
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Plants
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Seoul
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Wood*
3.Prognostic Significance Of Sequential 18f-fdg Pet/Ct During Frontline Treatment Of Peripheral T Cell Lymphomas
Ga-Young SONG ; Sung-Hoon JUNG ; Seo-Yeon AHN ; Mihee KIM ; Jae-Sook AHN ; Je-Jung LEE ; Hyeoung-Joon KIM ; Jang Bae MOON ; Su Woong YOO ; Seong Young KWON ; Jung-Joon MIN ; Hee-Seung BOM ; Sae-Ryung KANG ; Deok-Hwan YANG
The Korean Journal of Internal Medicine 2024;39(2):327-337
Background/Aims:
The prognostic significance of 18F-fluorodeoxyglucose (FDG)-positron emission tomography-computed tomography (PET/CT) in peripheral T-cell lymphomas (PTCLs) are controversial. We explored the prognostic impact of sequential 18F-FDG PET/CT during frontline chemotherapy of patients with PTCLs.
Methods:
In total, 143 patients with newly diagnosed PTCLs were included. Sequential 18F-FDG PET/CTs were performed at the time of diagnosis, during chemotherapy, and at the end of chemotherapy. The baseline total metabolic tumor volume (TMTV) was calculated using the the standard uptake value with a threshold method of 2.5.
Results:
A baseline TMTV of 457.0 cm3 was used to categorize patients into high and low TMTV groups. Patients with a requirehigh TMTV had shorter progression-free survival (PFS) and overall survival (OS) than those with a low TMTV (PFS, 9.8 vs. 26.5 mo, p = 0.043; OS, 18.9 vs. 71.2 mo, p = 0.004). The interim 18F-FDG PET/CT response score was recorded as 1, 2–3, and 4–5 according to the Deauville criteria. The PFS and OS showed significant differences according to the interim 18F-FDG PET/CT response score (PFS, 120.7 vs. 34.1 vs. 5.1 mo, p < 0.001; OS, not reached vs. 61.1 mo vs. 12.1 mo, p < 0.001).
Conclusions
The interim PET/CT response based on visual assessment predicts disease progression and survival outcome in PTCLs. A high baseline TMTV is associated with a poor response to anthracycline-based chemotherapy in PTCLs. However, TMTV was not an independent predictor for PFS in the multivariate analysis.