OBJECTIVE: To systematically review the effect of acupuncture on emotional disorder in the patients with migraine and knee osteoarthritis and its effect time limit. METHODS: The randomized controlled trials of acupuncture for migraine or knee osteoarthritis were retrieved from the databases, starting from the time of establishment through to December, 2018, i.e. the Cochrane Library, PubMed, EMbase, CNKI, SinoMed, VIP and Wanfang. The bias risk assessment tool of Cochrane Review Manual 5.1.0 was adopted to evaluate the quality of trials in methodology. RevMan 5.3 software was used for the Meta-analysis. RESULTS: A total of 12 articles were included, with 2450 cases. Regarding the immediate effect, the score of the emotional function subscale of migraine-specific quality-of-life questionnaire (MSQ) in the acupuncture group was higher than the control group (6.38[2.78,9.98], =25%). In view of the emotional function subscale of the short-form of health survey (SF-36/SF-12), and the scores of the mental function and negative mode scale in Spain's index of quality of life (PQLC), there were no significant differences in the scores between the acupuncture group and the control group. In 3 months of treatment, the score of the emotional function subscale of MSQ in the acupuncture group was higher than the control group (9.66 [3.06,16.25], =44%). The difference in the score of the mental health subscale of SF-36 and SF-12 was not significant between the acupuncture group and the control group. In 3 to 6 months of treatment, as well as in over 6 months of treatment, the score of every scale was not different statistically between the acupuncture group and the control group. CONCLUSION Acupuncture effectively maintains the healthy emotion in the patients with migraine and the effect is sustainable for 3 months after treatment. But the improvement of acupuncture is not remarkable in emotional disorder induced by knee osteoarthritis.
Acupuncture Therapy ; Chronic Pain ; psychology ; therapy ; Emotions ; Humans ; Migraine Disorders ; psychology ; therapy ; Osteoarthritis, Knee ; psychology ; therapy ; Quality of Life ; Treatment Outcome

BACKGROUND/AIMS: Gastric stasis in migraineurs remains controversial. The aim of this study is to investigate gastric emptying (GE) time, and any associations between GE parameters and dyspeptic symptoms among patients with functional dyspepsia (FD) and migraine without any gastrointestinal symptoms during the interictal period. METHODS: We enrolled 27 migraine patients, 32 FD patients and 12 healthy people as controls, and performed GE scintigraphy as gastric function test. Gastrointestinal symptoms were evaluated in the FD and migraine. RESULTS: The age-adjusted mean gastric half-emptying time in FD (125.51 +/- 52.55 minutes) patients was longer than in migraineurs (100.82 +/- 23.94 minutes, P = 0.035) and controls (95.25 +/- 23.29 minutes, P = 0.021). The percentage of gastric retention was higher in FD than in migraine. However, migraineurs did not show an obvious delayed gastric emptying or an increase of gastric retention when compared to the normal controls. The association between each dyspeptic symptom and GE parameters was not significant, but postprandial fullness and early satiety showed a tendency of delayed GE. In migraineurs, GE time did not show significant association with nausea and vomiting during interictal periods. CONCLUSIONS: Delayed GE does not appear to be a mechanism that patients with FD and migraine have in common. Migraineurs without dyspepsia during interictal period had normal GE, and further study for association with FD should be investigated.
Dyspepsia ; Gastric Emptying ; Gastroparesis ; Humans ; Migraine Disorders ; Nausea ; Retention (Psychology) ; Vomiting

BACKGROUND: Psychosocial factors exert a significant influence on primary headaches. However, little has been known about the agreement concerning the extent and nature of psychological processes on migraine and tension-type headache (TTH). METHODS: Fifty-five patients with primary headache were enrolled to participate in the study and 33 headache-free control subjects. A depression scale (BDI), an anxiety scale (STAI), a psychopathology scale (SCL-90-R), a stress coping scale (MCS), and a quality-of-life scale (WHOQOL-BREF) were administered to all the participants. RESULTS: The headache sufferers turned out to have various emotional problems, used more inefficient stress coping strategies and lead poor quality of life compared with those who had no headache. No distinctive psychological symptom was found between the two diagnosis groups, but the migraine group showed higher obsessive-compulsive symptoms than the TTH group, and the latter group showed higher levels of trait anxiety than the former. CONCLUSIONS: This study shows that the primary headache sufferers have various psychosocial problems. Accordingly, individual treatment approach focusing on the psychological symptoms is needed for the efficient management of headache.
Anxiety ; Depression ; Diagnosis ; Headache ; Humans ; Migraine Disorders* ; Psychology ; Psychopathology ; Quality of Life ; Tension-Type Headache*

The article presents an original method for the automatic assessment of the quality of event-related potentials (ERPs), based on the calculation of the coefficient ε, which describes the compliance of recorded ERPs with some statistically significant parameters. This method was used to analyze the neuropsychological EEG monitoring of patients suffering from migraines. The frequency of migraine attacks was correlated with the spatial distribution of the coefficients ε, calculated for EEG channels. More than 15 migraine attacks per month was accompanied by an increase in calculated values in the occipital region. Patients with infrequent migraines exhibited maximum quality in the frontal areas. The automatic analysis of spatial maps of the coefficient ε demonstrated a statistically significant difference between the two analyzed groups with different means of migraine attack numbers per month.
Humans ; Chronic Pain ; Evoked Potentials ; Migraine Disorders/psychology* ; Occipital Lobe ; Electroencephalography

Chronic headache is commonly encountered in the neurology outpatient clinic and it is often associated with depression. In Korea, however, chronic headache has not yet been systematically investigated. We conducted this study to investigate this clinical characteristics and level of depression in patients who presented migraine, tension-type headache, or transformed migraine. METHOD: Among those with chronic headache during the period from January 1, 1994 through December 31, 1994, 131 patients were diagnosed to have either migraine, tension-type headache (by IHS classification), or transformed migraine: migraine in 60 patients, tension-type headache in 49 patients, and transformed migraine in 22 patients. Beck Depression Inventory (BDI) was performed in 116 of the 131 patients. RESULTS & CONCLUSION: There was no significant difference in the age of onset, duration of headache, and family history among the three groups. However, patients with migraine had a more severe, unilateral, and throbbing characteristic pain than those with a tension-type headache. The mean BDI scores in the transformed migraine and the tension-type headache patients were significantly higher than those of migraine, but the level of depression did not correlate with the patient's age, duration, character, severity, and frequency of headache. These findings suggest that migraine, tension-type headache and transformed migraine may be considered clinically distinct entities in viewing their different clinical characteristics and level of depression.
Adolescent ; Adult ; Aged ; Child ; Chronic Disease ; Comparative Study ; Depression/*psychology ; Female ; Human ; Male ; Middle Age ; Migraine/*psychology ; Support, Non-U.S. Gov't ; Tension Headache/*psychology

Headache is one of the meet common symptoms in neurological outpatient clinic. It is not so easy for physicians and neurologists to manage headache, especially if it is chronic although it seldom causes serious problem. There are many psychological factors known to induce, maintain and aggravate symptom in patients with chronic headache. Thus it is necessary to identify these factors in each patient when planning therapeutic strategies. In order to assess the influence of psychological characteristics, such as depression, anxiety and stress, on therapeutic outcome in patients with chronic headache, I performed Beck depression inventory (BDI), General assessment of recent stress scale (GARS) and State-trait Anxiety inventory (STAI) in 13 patients with migraine, 14 with tension-type headache and 29 with unclassified headache, meet of whom are with mixed or chronic daily headache. In all patients the duration of headache is more than one year. The effect of therapy (flunarizine + amitriptyline or moclobemide) was assessed using self-rating headache index after three months. Patients in unclassified group were significantly older and had longer duration of symptoms than other groups. While GARS and STAI scores were comparable among groups, the BDI score in unclassified group was significantly higher than other groups. The therapeutic response was relatively poor in patients in unclassified group and patients with long-term analgesics abuse, compared with other groups. The poor responders to therapy showed higher BDI and STAI more than moderate as well as good responders. Sbepwise regression analysis was performed to exclude interactions between psychological characteristic, and it revealed depression is the strongest variable influencing therapeutic outcome. These results suggest; first, there are no significant differences in psychological characteristics between migraine and tension-type headache; second, patients with depressive trait are prone to have chronic daily headache; third, among the psycholog
Ambulatory Care Facilities ; Amitriptyline ; Analgesics ; Anxiety ; Depression ; Headache ; Headache Disorders* ; Humans ; Migraine Disorders ; Psychology ; Tension-Type Headache

BACKGROUND/AIMS: Migraine is frequently accompanied by symptoms consistent with functional gastrointestinal disorders (FGIDs). This study evaluated the prevalence of functional gastrointestinal symptoms and assessed the symptoms' relationship with the concomitant functional symptoms of anxiety, depression, and headache-related disability. METHODS: This prospective study included 109 patients with migraine who were recruited from a headache clinic at a teaching hospital. The participants completed a self-administered survey that collected information on headache characteristics, functional gastrointestinal symptoms (using Rome III criteria to classify FGID), anxiety, depression, and headache-related disability. RESULTS: In total, 71% of patients met the Rome III criteria for at least one FGID. In patients with FGID, irritable bowel syndrome was the most common symptom (40.4%), followed by nausea and vomiting syndrome (24.8%) and functional dyspepsia (23.9%). Depression and anxiety scores were significantly higher in patients meeting the criteria for any FGID. The number of the symptoms consistent with FGID in individual patients correlated positively with depression and anxiety. CONCLUSIONS: FGID symptoms defined by the Rome III criteria are highly prevalent in migraine. These symptoms correlate with psychological comorbidities, such as depression and anxiety.
Adolescent ; Adult ; Aged ; Anxiety/epidemiology/psychology ; Comorbidity ; Depression/epidemiology/psychology ; Disability Evaluation ; Dyspepsia/epidemiology/psychology ; Female ; Gastrointestinal Diseases/*epidemiology/*psychology ; Humans ; Male ; Middle Aged ; Migraine Disorders/*epidemiology/*psychology ; Nausea/epidemiology/psychology ; Prevalence ; Prospective Studies ; Republic of Korea ; Vomiting/epidemiology/psychology ; Young Adult

OBJECTIVES: This study aimed to examine the effect of biofeedback treatment on the clinical symptoms and stress responses in chronic headache patients. METHODS : We recruited 18 chronic headache patients who were treated with 8 sessions of biofeedback treatment and 18 age and sex-matched control headache patients. All subjects consisted of patients with chronic tension headache and migraine headache. Stress responses were measured using Symptoms of stress (SOS) inventory and all subjects performed Beck depression inventory (BDI), Spielberger state anxiety inventory (STAIS), and visual analogue scale (VAS). Biofeedback physiological variables including frontal and forearm EMG, electrodermal response (EDR) and skin temperature at pre-and post-treatment were also measured in all subjects. RESULTS : Compared with control patients, patients on biofeedback treatment showed significant reduction in scores of STAIS (t=3.705, p<.001), and VAS (t=3.392, p=.001) as well as SOS subscales;peripheral manifestations (t=1.788, p=.042), habitual patterns (t=2.008, p=.027), depression (t=2.081, p=.023), anxiety (t=1.990, p=.028), and total score (t=2.045, p=.025). There was a significant increase of skin temperature (t=-1.835, p=.038) only in the biofeedback treatment group. CONCLUSION : These results suggest that biofeedback treatment may be effective in relieving chronic headache by reducing psychological and physiological stress responses.
Anxiety ; Biofeedback, Psychology ; Depression ; Forearm ; Galvanic Skin Response ; Headache ; Headache Disorders* ; Humans ; Migraine Disorders ; Relaxation* ; Skin Temperature ; Stress, Physiological ; Tension-Type Headache

Biofeedback with or without combined autogenic training is known to be effective for the treatment of migraine. This study aimed to examine the effect of biofeedback treatment on headache activity, anxiety, and depression in Korean female patients with migraine headache. Patients were randomized into the treatment group (n=17) and monitoring group (n=15). Mood states including anxiety and depression, and psychophysiological variables such as mean skin temperature of the patients were compared with those of the normal controls (n=21). We found greater treatment response rate (defined as > or =50% reduction in headache index) in patients with biofeedback-assisted autogenic training than in monitoring group. The scores on the anxiety and depression scales in the patients receiving biofeedback-assisted autogenic training decreased after the biofeedback treatment. Moreover, the decrease in their anxiety levels was significantly related to the treatment outcome. This result suggests that the biofeedback-assisted autogenic training is effective for the treatment of migraine and its therapeutic effect is closely related to the improvement of the anxiety level.
Adult ; *Affect ; Analysis of Variance ; Anxiety ; Autogenic Training/*methods ; Biofeedback, Psychology/*methods ; Body Temperature ; Depression ; Female ; Humans ; Migraine Disorders/*therapy ; Republic of Korea ; Severity of Illness Index

OBJECTIVEBy using questionnaire method to understand the evaluation regarding cost-effectiveness of acupuncture for migraine in both doctors and patients.

METHODSBy using questionnaire method, questionnaires for doctors and patients were made respectively; by using network platform, two sets of questionnaires were publicly released, which were filled in online. The results were real-time background collected and then analyzed.

RESULTSTotally 696 effective questionnaires for patients and 114 questionnaires for doctors were collected. The results indicated that (1)the direct cost (including treatment fee and material fee) for preventive treatment of migraine was 109 yuan per time in regular acupuncture, 152 yuan per time in regular acupuncture + electroacupuncture (EA) and 238 yuan per time in acupoint catgut embedding. The travelling expense was 42 yuan per time within the city and 193 yuan per time between cities. The indirect cost included cost for loss of working time (208 yuan per time), cost for treatment time (acupoint catgut embedding: 10 to 30 min per time, once one to three weeks; the remaining two treatments: 20 to 50 min per time, once to 5 times every week), time cost for arriving and departing hospital (1 to 3 hours per time within the city and 4 hours per time between cities). From the angle of treatment course, acupoint catgut embedding reduced the treatment frequency, leading to a lower total cost. (2)A mong the reasons to select different acupuncture methods to treat migraine, the results of patient questionnaire indicated that the focus in the patients who selected acupoint catgut embedding was different from that in the patients who selected two other treatments. The main advantage of acupoint catgut embedding was superior and lasting efficacy with low cost. The results of doctor questionnaire indicated the main reason to select acupoint catgut embedding was "lasting efficacy after single treatment" (87. 5%) and "lower frequency of treatment" (75. 0%). (3) The main reason to obstruct the popularization of acupoint catgut embedding was this method was not widely known.

CONCLUSIONThe acupoint catgut embedding is one ideal preventive treatment for migraine, which has higher cost-effectiveness, however, currently it is not widely applied. In future advertisement and training program should be strengthened to perform targeted popularization of acupoint catgut embedding for migraine.

Acupuncture Therapy ; economics ; Adolescent ; Adult ; Aged ; Cost-Benefit Analysis ; Female ; Health Care Costs ; Humans ; Male ; Middle Aged ; Migraine Disorders ; economics ; psychology ; therapy ; Surveys and Questionnaires ; Young Adult