No abstract available.
Arthrodermataceae ; Microsporum*

No abstract available.
Granuloma* ; Microsporum* ; Tinea*

No abstract available.
Microsporum ; Tinea Capitis

Ringworm infections have been extensiveIy studied in Korea since 1943. However, only two cases of ringworrn caused by Microsporum gypseum were reported until 1975. The authors experienced an increase of M. gypseum infection in recent years, suggesting a further increase in incidence in the future. Therefore, the authors studied the cIinical and mycological findings of 14 cases of M. gypseum infection encountered from 1976 to l978, along with the distribution of various dermatophytoses observed in recert years. To investigate possible sources of infection, mycological characteristics of M. gypseum strains isolated from human and soil were compared. (countinued...)
Humans ; Incidence ; Korea ; Microsporum* ; Soil ; Tinea

BACKGROUND: Trichophyton(T.) mentagrophytes is one of common dermatophytes in Korea. The strain has a various colonial morphology; the colonial morphology of granular and powdery forms is very similar to Microsporum(M.) persicolor. OBJECTIVE: We tried to evaluate the mycologic features of T. mentagrophytes and to investigate the possibility of existence of M. persicolor among granular forms of T. mentagrophytes isolated in Korea. METHODS: Fifty strains of T. mentagrophytes var. mentagrophytes were examined and compared with standard strain of RV 28710 Nannizzia (Arthroderma) persicolor(+), RV 28709 Nannizzia (Arthroderma) persicolor (-), RV 27960 Arthroderma vanbreuseghemii(+), RV 27961 Arthroderma vanbreuseghemii (-), RV 26678 Arthroderma benhamiae (+) and RV 26680 A
Arthrodermataceae ; Daegu* ; Humans ; Korea ; Microsporum* ; Tinea* ; Trichophyton*

Tinea capitis in the neonatal period is extremely rare. To our knowledge, there have been only a few reports of neonatal tinea capitis in the Korean dermatologic literature. We report an additional case of neonatal tinea capitis caused by Microsporum canis. The patient was successfully treated with oral griseofulvin.
Griseofulvin ; Humans ; Microsporum ; Tinea Capitis* ; Tinea*

A keratinolytic proteinase secreted by Microsporum canis in a broth containing human hair was purified 134-fold from the culture filtrate by ion-exchange chromatography using DEAE-Sephacel, CM-Sephadex C-50, and by Sephadex G-75 gel filtration. The purified enzyme was electrophoretically homogeneous with a molecular weight of 33,000. The enzyme had an optimum pH of 8.0, and the activity was stable in the alkaline pH range. Enzyme activity increased with temperature up to 35 degrees C and was stable up to 45 degrees C. The keratinolytic activity was not affected by the addition of nonionic detergents, was activated by Mg2+, but inhibited by Zn2+. The purified enzyme was used to obtain guinea pig antiserum. The antiserum tested by double diffusion against the purified enzyme showed a single line of precipitation and completely neutralized the proteinase activity. This study reaffirms that the proteinase from M. canis may be a biochemical mechanism for the invasion of keratinized tissue, and could possibly play a role in the hypersensitivity reactions arising from superficial infections of this fungus.
Microsporum/enzymology* ; Peptide Hydrolases/isolation & purification*

We present a case of white superficial onychomycosis(WSO) caused by Microsporum canis in a 15-year-old girl. She complained whitish patches and irregularly pitted surface of the right thumb nail, clinically suggesting WSO. On the mycologic studies, the nail lesion was diagnosed as WSO caused by Microsporum canis.
Adolescent ; Female ; Humans ; Microsporum* ; Onychomycosis* ; Thumb

No abstract available.
Humans ; Microsporum* ; Siblings* ; Tinea Capitis* ; Tinea*

Dermatophytes are keratinophilic fungi responsible for superficial infections called dermatophytoses and composed of three anamorphic genera, Trichophyton, Microsporum and Epidermophyton. The identification of these species by mycological methods is sometimes difficult and time-consuming. Moreover, suitable methods for subtyping of these species are not established yet. Therefore, several approaches using molecular biological methods have been proposed to identify dermatophyte species and to clearly define their taxonomic and phylogenetic relationship to the teleomorphs and to other dermatophyte species. For identification, distinction among isolates to the species level was easily performed using molecular biological methods, particularly for atypical isolates. In contrast, in all but a few cases, distinction between dermatophyte strains failed. The development of new techniques to reveal molecular polymorphisms in dermatophytes is required.
Arthrodermataceae* ; Epidermophyton ; Fungi ; Microsporum ; Molecular Biology ; Tinea ; Trichophyton