Microphthalmos is a uncommon congenital ocular anomaly and the term is justified in that in all cases the eyes are smaller than normal. Microphthalmos is classified as various forms according to degrees of developmental abnormality. The authors experienced a case of microphthalmos with a large cyst in one eye and colobomatous microphthalmos in the other eye.
Coloboma ; Microphthalmos*

Anophthalmos is a complete absence of the tissues of the eye. Embryologically, anophthalmos denotes those cases wherein there is complete failure in the outgrowth of the primary optic vesicle. When essential structures of the eye are present, the aonormality is microphthalmos, no matter how small the eye may be. Clinical anophthalmos represents the majority of cases in which the eye appears to be absent. Congenital anophthalmos is one of the rare ophthalmic anomalies, only 5 cases were reported in Korea and about 100 cases in the world. We report this case with a brief review of literatures.
Anophthalmos* ; Korea ; Microphthalmos

No abstract available.
Choanal Atresia* ; Microphthalmos*

Congenital anophthalmos is fairly rare malformation in which the eyeball is apparently absent. We experienced a 10-day-old boy, who had a congenital anophthalmos of his left eye, a microphthalmos of the other eye and short palpebral fissure of both eyes(right: 12mm, left: 5mm). The absence of left eyeball within a small orbit was confirmed by C-T scanning. We report this interesting case with a brief review of literatures.
Anophthalmos* ; Humans ; Male ; Microphthalmos ; Orbit

Congenital cryptophthalmos is very rare, according with Duke-Elder's System of Ophthalmology(Volume 3, Part 2) some 50 cases having been recorded since Zehender and Manz's(1872) original observation. I observed the congenital ocular deiermities in siblings; out of 10 siblings, 2 were affected. A 15-year old girl had cryptophthalmos unilaterally with other gross anomalies of the face. One of her brother (27-year old) had congenital microblepharon, coloboma of eyelids, microphthalmos and symblepharon bilaterally. The surgical amelioration of cryptophthalmos was attempted but it was impossible.
Adolescent ; Coloboma ; Eyelids* ; Female ; Humans ; Microphthalmos ; Siblings*

Microphthalmos with cyst which results from a defect of ventral fissure is a rare malformation, with no previously reported case in Korea. The defect permits neuroectodermal tissue to proliferate into the orbit, forming a cystic structure that remains connected to the inferior aspect of the diminutive globe. We have observed such a malformation in a 8-year-old girl and surgically excised the diminutive eye and communicating cyst en-bloc.
Child ; Female ; Humans ; Korea ; Microphthalmos* ; Neural Plate ; Orbit

Complicated microphthalmos can be diagnosed when a reduction in global dimension is combined with other structural anomalies. These include corneal opacity or staphyloma, cataract, aniridia, corectopia, persistence of pupillary membrane or the tunica vasculosa lentis and hyaloid vessel, thickening or ossification of the choroid and various retinal anomalies. Complicated microphthalmos is frequently hereditary and the transmission may be either as an autosomal dominant or recessive or as a sex linked recessive trait. Four cases of bilateral complicated microphthalmos with cataract were found in a family.
Aniridia ; Cataract ; Choroid ; Corneal Opacity ; Humans ; Membranes ; Microphthalmos* ; Retinaldehyde

Twenty years old Korean male patient with Hallermann-Streiff syndrome who developed glaucoma is reported. The clinical features are dyscephalia with mandibulo-oculo-facial malformation, bilateral congenital cataract, dental anomalies, hypotrichosis, microphthalmia, nanism and the secondary complications. A brief review of literature is described.
Cataract ; Dwarfism ; Glaucoma ; Hallermann's Syndrome* ; Humans ; Hypotrichosis ; Male ; Microphthalmos

Microcornea is a condition characterized by a small cornea in an otherwise normal eye and can be defined when corneal diameter is less than 11.00mm. Microcornea may occur as an isolated abnormality or accompany other anterior segment anomalies like aniridia and anterior chamber cleavage abnormalities. Microcornea is part of nanophthalmos, a condition in which a reduction in global dimensions is the only structural abnormality, as well as microphthalmos, a term generally, used to signify a small, abnormal globe. Microcornea is a rare anomaly and its etiology is probably a primary aberration of the growth of the ectoderm of the optic cup. Both autosomal dominant and autosomal recessive patterns of inheritance occur, but it may appear sporadically. Cornea plana is usually seen in association with microcornea wherein the corneal curvature is less than normal. It is often associated with diffuse opacities of the cornea stroma. Cornea plana might be caused by a deep developmental arrest in the fourth month, at which time the cornea begins to increase its curvature relative to the sclera. The authors experienced a case of bilateral microcornea with cornea plana in a family which seemed to transmit as the dominant trait.
Aniridia ; Anterior Chamber ; Cornea* ; Ectoderm ; Humans ; Microphthalmos ; Sclera ; Wills

Microcornea is a condition characterized by a small cornea in an otherwise normal eye and can be defined when corneal diameter is less than 11.00mm. Microcornea may occur as an isolated abnormality or accompany other anterior segment anomalies like aniridia and anterior chamber cleavage abnormalities. Microcornea is part of nanophthalmos, a condition in which a reduction in global dimensions is the only structural abnormality, as well as microphthalmos, a term generally, used to signify a small, abnormal globe. Microcornea is a rare anomaly and its etiology is probably a primary aberration of the growth of the ectoderm of the optic cup. Both autosomal dominant and autosomal recessive patterns of inheritance occur, but it may appear sporadically. Cornea plana is usually seen in association with microcornea wherein the corneal curvature is less than normal. It is often associated with diffuse opacities of the cornea stroma. Cornea plana might be caused by a deep developmental arrest in the fourth month, at which time the cornea begins to increase its curvature relative to the sclera. The authors experienced a case of bilateral microcornea with cornea plana in a family which seemed to transmit as the dominant trait.
Aniridia ; Anterior Chamber ; Cornea* ; Ectoderm ; Humans ; Microphthalmos ; Sclera ; Wills