OBJECTIVETo explore methods for one-stage repairing of nose deformity and alveolar cleft, as well as primary unilateral complete cleft lip.

METHODSThe nose deformity and alveolar cleft were repaired by Carstens' surgical methods, rhBMP-2 was used for correction of alveolar cleft.

RESULTSFrom 2004 to 2008, 45 cases of cleft lip were treated in the United States and followed up for 3-5 years. In 2007, 10 cases of cleft lip were treated in China and followed up for 1 year. All results were satisfactory.

CONCLUSIONSCarstens' surgical methods can be applied for early correction of nose deformity and alveolar cleft in patients with complete cleft lip.

Alveolar Process ; abnormalities ; Bone Morphogenetic Protein 2 ; Bone Morphogenetic Proteins ; therapeutic use ; Cleft Lip ; surgery ; Female ; Follow-Up Studies ; Humans ; Infant ; Male ; Nose ; abnormalities ; Recombinant Proteins ; therapeutic use ; Reconstructive Surgical Procedures ; methods ; Surgical Flaps ; Transforming Growth Factor beta ; therapeutic use