1.Researchprogress of radar for non-contact medical monitoring
Chinese Medical Equipment Journal 2015;36(5):107-111
The advantages of non-contact medical monitoring radar were introduced compared with the traditional medical monitoring devices. The state of art of three kinds of typical medical monitoring radar schemes over the past decade was reviewed. Researches on breathing and heartbeat signal extraction, isolation and clutter suppression algorithms were summarized. The advantages and disadvantages of these algorithms were also pointed out. The prospects of non-contact medical monitoring radar were explored finally.
2.Study of prognostic factors in patients with acute respiratory failure due to chronic obstructive pulmonary Disease
Clinical Medicine of China 2008;24(8):787-789
Objective To explore the prognostic factors in patients with acute respiratory failure due to chronic obstructive pulmonary disease (COPD) in EICU. Method Clinical data of 39 patients admitted to EICU from May 2005 to May 2007 were retrospectivley analyzed. Results In death group, the pulmonary artery pressure (PAP) ,creatinine (Cr) ,APACHE-Ⅱ score, and APACHE-Ⅲ score were increased (P < 0. 05) and ICU stays were prolonged (P < 0.05) ; Respiratory rate (RR) and Glasgow coma score (GCS) were decreased (P < 0.05). Conclusion PAP, Cr, APACHE-Ⅱ score,APACHE-Ⅲ score,RR and GCS predict the prognosis of the patients with acute respiratory failure due to chronic obstructive pulmonary disease.
3.Treatment of urethral stricture and occlusion(report of 154 cases)
Chun LIU ; Dongwen WANG ; Zhenguo MI
Chinese Journal of Urology 2000;0(05):-
Objective To make the surgical therapy of urethral stricture and occlusion more effective. Methods 154 patients treated in our hospital were included in this retrospective study,of these cases,40 cases were in anterior urethra and 114 in posterior part.Based on etiology,106 cases were from trauma,15 from infection and 33 from idiopathic causes.Open surgery was performed on 34 cases and endoscopic therapy on 120 cases. Results All of the anterior urethral cases were treated successfully,among them,18 cases were with open surgery and 22 with endoscopic surgery.Normal urination was achieved on the follow-up from 6 months to 12 months.Within posterior urethral stricture and occlusion situation,open surgery was in 16 cases with 10 cases of normal urination and endoscopic surgery in 98 cases with 92 cases of normal urination.6 cases with open surgery and 5 cases with endoscopy resulted in postoperative dysuria or anuria.Urethral stricture and occlusion were shown in all these unsuccessful operation according to our urethrogram. Conclusions Good result can be achieved by both open and endoscopic surgery in anterior urethral stricture.In case of posterior urethral condition,endoscopic procedure is the best choice.
4.Application Study of Thinprep Liquid Based Cytology Test in the Detection of Cervical Diseases
Xianjun MI ; Baoming BAI ; Yong LIU
Journal of Chinese Physician 2001;0(04):-
Objective To assess the value of thinprep liquid based cytology test (TCT) and Besthesda system (TBS) in diagnosis of cervial lesions. Methods 11000 cases of cervical lesions were detected with TCT and TBS.The samples of atypical squamous cells(ASC) and more severe than ASC lesions were classified into postive cytology,and then cytological results were compared with pathological examination results of cervical biopsies.Results The satisfactory rate of TCT samples was 96.36%, and the postive rate of abnormal epithelial cells diagnosed by TCT was 10.96%(1206/11000). Among 1206 cases, 15 cases(0.14%) of CA, 89 cases (0.81%) of HSIL, 449 cases (4.08%) of LSIL, 73 cases (0.66%) of ASC-H and 580 cases (5.27%) of ASC-US and AGUS. 1128 cases with postive cytologic results received pathological examination. The pathological positive rate of CA, HSIL, LSIL, ASC-H, and ASC-US and AGUS were 100%, 100%, 67.12%, 54.17% and 14.09%, respectively. The coincident rate of two examination methods was 100% for CA, 91.1% for HSIL,57.82% for LSIL and 27.78% for ASC-H. Conclusion TCT and TBS can accurately detect cervical cancer, precancerous lesions and infection of bacteria, virus and other pathogens, and at present is a means of screening cervical cancer.
5.The Quality Control and Targeting Studies of Anti-hepatoma Monoclonal Antibodies
Zhinan CHEN ; Li MI ; Zhiguang LIU
Chinese Journal of Cancer Biotherapy 1995;0(02):-
The cell suspensions prepared from surgically resected hepatoma specimens were used to immunize BALB/c mice and, with the hybridoma technique, a battery of high affinity monoclonal anti-hepatoma antibodies were obtained which were designated HAbl8, Fll, E5 and A10 separately. Immunohistochimical staining showed that the above 4 antibodies possessed good selective reactivity with hepatoma tissue. After radioiodination of Fll, E5, A10, HAbl8 IgG and It's F(ab')_(2) fragments, the labelled reagents were employed for radioimmunoimaging in hepatoma-bearing nude mice and the in vivo detection appeared promising, with tumor/non-tumor ratios being 6.88, 5.14, 5.67, 5.15 and 14.47 respectively. The in vivo localization ablities of the antibodies seemed better compared to other similar findings published elswhere (Dunk AA, 1987). Also, ~(131) I -HAbl8 I gG and its radiolabelled fragments were utilized for radioimmunotherapy in hepatoma-bearing nude mice, with complete response rate and partial response rate being 42%(5/12) and 50% (6/12)respectively. When the HAbl8 conjugate with radioiodine was introduced for the in vivo imaging in hepatoma patients, a positivity rate of 86.5% (45/52)was witnessed, with the smallest tumor foci detected being only 0.5cm in diameter. In the in vivo targeting therapy with the immunoconjugate, a partial response rate of 69.6% (16/23) was obtained. In summary, the antibodies reported here have lended a novel regime for the present comprehensive therapy protocol of hepatoma.
6.Rapid detection of Escherichiacoli with test paper of Na p-nitrophenyl ?-D-Glucuronate
Jiali SUN ; Sha MI ; Xiaolan LIU
Chinese Journal of Laboratory Medicine 2001;0(03):-
Objective To develop a new method for rapid detection of E.Coli.with a new substrate Na p nitrophenyl ? D glucuronate (PNP Glucu Na). Method The test paper was immersed with of Na p nitrophenyl ? D glucuronate which was synthesized by us and another paper with culture medium and phorphate buffer.Colour change was observed to detect the E.coli. Results An E.coli concerntration of 4?10 7 took 0.5 hour, while a concentration of 4?10 0 took 12 hours. 138 strains of E.coli and 190 strains of other bacteria were examined . The sensitivity was 94.2% and the specificity was 92.6%. Conclusion This method is rapid, accurate, simple, and economical for detecting E.coli.
7.Expression of hepatocyte growth factor in the inflammatory periodontal tissue of rats during orthodontic tooth movement
Hong LIU ; Congbo MI ; Jun ZHU
Chinese Journal of Tissue Engineering Research 2014;(15):2377-2382
BACKGROUND:The cytokine has an effect of immunoregulation and immediate induction in the reconstruction of periodontal tissue. At present, the role and mechanism of hepatocyte growth factor involving the reconstruction of periodontal tissue under orthodontic force are stil unclear.
OBJECTIVE:To explore the mechanism underlying hepatocyte growth factor in the tooth movement and periodontal tissues remodeling under the inflammation periodontal tissue condition.
METHODS:Thirty Sprague-Dawley rats, aged 8 weeks, were used to establish periodontitis model. The obtained model was randomly divided into two groups:inflammatory control group and inflammatory force group. In the force group, rats were treated with the fixed orthodontic appliance by 50 g forces in the maxil ary first molars. After 1, 3, 5, 7 and 14 days of tooth movement, five rats were sacrificed respectively. Hematoxylin-eosin staining and immunohistochemistry methods were used to analyze the expression and distribution of hepatocyte growth factor in the periodontium for rats at different tooth movement stages.
RESULTS AND CONCLUSION:Hematoxylin-eosin staining results showed that, remodeling of periodontal tissues existed in al groups. (2) The immunohistochemical results showed that hepatocyte growth factor had positive expression in periodontal tissue, and the distribution was even in the control group. In the force group, hepatocyte growth factor expression was increased and reached the peak on day 5, then began to decline. Osteoblast, fibroblast and osteoclast were strongly expressed. The findings indicate that, hepatocyte growth factor is involved in the periodontal tissues remodeling under orthodontic force, and inflammation can increase the expression of hepatocyte growth factor in periodontal tissue.
8.Research and Application of SPR Sensor Technique in Biomedical Engineering
Yongwei MI ; Guohua LIU ; Wei ZHANG
Chinese Medical Equipment Journal 1993;0(06):-
The major developments in SPR technology are reviewed.The principle,parameters and configurations of SPR sensors are also introduced.Then the applications and future prospects of SPR sensor technology in biomedical engineering area are discussed.It is pointed out that the development of this technology tends to further improve the detection sensitivity and resolution,multi-channel detection,the array of micro-devices,etc.
9.Needle-Stick Injuries among 379 Nurses:Analysis and Surveillance
Guangli MI ; Yan TANG ; Ping LIU
Chinese Journal of Nosocomiology 2006;0(08):-
OBJECTIVE To investigate rate,cause,psychology and prevention of needle-stick injuries among nursing staff.METHODS A retrospective questionnaire was distributed to a convenience sample of 426 clinical nurses in a hospital.RESULTS Totally 379 nurses(88.97%) suffered from needle-stick injuries with an average of 4.75 times per person annually.The nurses with needle-stick more than 10 times accounted for 6.10%.The main reasons of needle-stick included pulling needles,adding medication,separating needle and so on.CONCLUSIONS Nurse should consolidate them self-protective consciousness.Therefore,it is a very important task of occupational prevention to improve the education of concept of universal precautions,prevent needle stab and reduce the occurrence of blood born diseases.
10.Vitrectomy combined with inferior scleral buckling for a special kind of retinal detachment
Heng, LI ; Zhi-Gang, LIU ; Xue, MI
International Eye Science 2014;(8):1519-1521
AIM:To evaluate the efficiency of vitrectomy combined with inferior scleral buckling for a special kind of retinal detachment.
METHODS: Nineteen eyes of special retinal detachment had following features: 1 ) the course was more than 6mo;2) there were at least one hole located in the 5 : 00 - 7 : 00 of the marginal retina; 3 ) the detachment range of retina more than 270 degrees and retinal proliferation in retinal detachment. The 19 eyes who received vitrectomy combined with inferior scleral buckling, retinal anatomic reattachment and visual function recovery was observed.
RESULTS: Among these 19 eyes, all eyes retinal anatomic reattachment and best corrected visual acuity ( BCVA ) was improved in various degrees. The BCVA was 0. 01-0. 1 in 5 eyes, 0. 12-0. 3 in 9 eyes, and ≥0. 4 in 5 eyes.
CONCLUSION: It is an effective method to vitrectomy combined with inferior scleral buckling for the special kind of retinal detachment which has following features:1) the course was more than 6mo;2) there were at least one hole located in the 5:00-7:00 of the marginal retina;3 ) the detachment range of retina more than 270 degrees and retinal proliferation of cable in retinal detachment.