The purpose of this study is to determine the effect of oral vitamin C supplements on blood sugar and serum lipid level (total cholesterol, triglyceride. high density lipoprotein. low density lipoprotein) in non-insulin independent diabetes mellitus. The study design was a non equivalent control group pre-test post-test design. Data for the study were collected from June 24 to August 31. 2001. The ninty-five research subject were assigned to experimental group(51) and control group(44). Vitamin C(3g/day) was given to 51 subjects for 4 weeks. Following a 12h overnight fasting, blood sample was obstaind at baseline and at the end of 4week - supplementation. Blood samples were taken for plasma vitamin C concentration. fasting blood sugar. HbA1c and serum lipid level. The pre-equivalent test was used by Chi-squre, t-test and two group's pre and post experimental differences were analyzed by t-tset to compare with each other. The results of this study were as follows: 1. The difference between the two groups in plasma vitamin C concentration was significant(t=-12.950. p=.000). 2. The difference between the two groups in fasting blood sugar was significant(t=5.293, p=.000). 3. The difference between the two groups in HbA1c was not significant(t=1.758. p= .082). 4. The difference between the two groups in total cholesterol, HDL, LDL was significant (t=3.786. p=.000 ; t=-5.515. p=.000 . t= 4.169. p = .000). These results suggest that megadose vitamin C supplementation be effective in lowering fasting blood sugar. serum lipids and increasing plasma vitamin C. Thus dietary measures to increase plasma vitamin C may be on important health strategy for reducing the compliance of diabetic patients.
Ascorbic Acid* ; Blood Glucose* ; Cholesterol ; Cholesterol, HDL ; Compliance ; Diabetes Mellitus ; Diabetes Mellitus, Type 2* ; Fasting ; Humans ; Lipoproteins ; Plasma ; Research Subjects ; Triglycerides ; Vitamins*

The purpose of this study is to determine the effect of diabetes education program on Glucose Metabolism(blood sugar. HbAlc) and Lipid Metabolism(total cholesterol. triglyceride. low density lipoprotein. high density lipoprotein). Self-efficacy in non-insulin independent diabetes mellitus. The study design was a non equivalent control group pre-test post-test design. Data for the study were collected from March 12 to June 19, 2001. Sixty-two research subjects were assigned to experimental (36) and control (26) groups. The collected data was analyzed using the Chi-Square test. t-test by spsswin program The results are as follows: 1. Experimental group had higher level of glucose metabolism than control group(FBS: t=-3.317. p=.002. HbAlc: t=-4.956. p=.000). 2. Level of lipid metabolism were partly a significant different between experimental group and control group(Triglyceride: t=-2.108. p=.039). 3. Experimental group had higher efficacy score than control group(t=4.651. p=.000). In conclusion. the study supported the effects of diabetes education program to increase metabolism and self-efficacy. Further study with a longitudinal design is suggested to verify the effect of diabetes education program in NIDDM and standardized diabetes education program.
Cholesterol ; Diabetes Mellitus ; Diabetes Mellitus, Type 2* ; Education* ; Glucose* ; Humans ; Lipid Metabolism* ; Lipoproteins ; Metabolism* ; Research Subjects ; Triglycerides

The purpose of this study is to determine the effect of a health management program on body composition(body weight, body fat mass, body fat ratio, lean body mass, abdominal fat ratio), self-efficacy and health promotion behavior in middle-aged women. This 6-week long program containing exercise and health education was developed by researchers. The study design was one group pretest- posttest design. Data for the study was collected from August 1 to September 15, 2002. The participants consisted of 15 middle - aged women living in the community. The collected data was analyzed using Wilcoxon Matched - Signed - Ranks Test by SPSS/WIN program The results are as follows: 1. There was a significant difference in body composition at week 6 compared to week 1. The body weight, body fat mass and body fat ratio significantly decreased(Z= -2.533, p=. 011 ; Z= -2.023, p= .043; Z= -2.023, p= .043). But the lean body mass significantly increased(Z= -2.226, p= .026). 2.There was a significant improvement in self-efficacy at week 6 compared to week 1(Z= -3.434, p= .001). 3.There was a significant improvement in health promotion behavior at week 6 compared to week 1(Z = -3.305, p= .001). In conclusion, health management program promoting self - efficacy for middle-aged women was effective in improving health promotion behavior. Further study with a longer follow up period is necessary in order to test the long term effect of the program.
Abdominal Fat ; Adipose Tissue ; Body Composition* ; Body Weight ; Female ; Follow-Up Studies ; Health Education ; Health Promotion* ; Humans

No abstract available.

Primary malignant lymphoma of the appendix is an unconnnon neoplasm although the gastrointestinal tract is the most common extranodal site of malignant lymphoma. We report a case of primary malignant lymphoma of the appendix in a 54-year-old male, who presented with pain in the right lower abdomen. An appendectomy was performed. The appendix measured 9.5 cm in length and 5.5 cm in diameter. Cut sections showed a solitary circumferential mass in the appendiceal lumen. Light microscopic features were compatible with malignant lymphoma of diffuse large cell type(Working Formulation) and the immunophenotype was B cell type.

PURPOSE: To evaluate the size of normal pons and cerebellum in vivo and the change in size according to age, and to compare those with measurement of the diseased pons and cerebellum. MATERIALS AND METHODS: 121 normal adults(M:F=54:67), 5 patients with OPCD and 19 patients with WallerJan degeneration were studied. The normal group was divided into 5 subgroups according to the age (ranged from 20 to 72 years). 1.5T GE Signa MR unit was used. On axial plane, the AP(A) and transverse(B) diameters of the pons, the size of the middle cerebellar peduncle(C), and transverse diameter of the posterior fossa(D) and the cerebellum(E) were measured. On midsagittal plane, the longitudinal(F) and AP(G) diameters of the basis pontis were measured. The ratios of E/D and F/G were calculated. The student t test was used for statistical analysis. RESULTS: C, E and F/G were 15.5mm+/-1.3, 99.8mm+/-4.3 and 1.63+/-.10, respectively. F/G, H/I, and H/J were larger in male(p<.01). All data of the pons showed no statistically significant differences among age groups. E of the seventh decades was shorter than that of the third decades(p<.05). C(12.7 mm+/-1.4) in OPCD and F/G(1. 81+/-.10) in Wallerian degeneration(p<.01) showed the most significant differences when they were compared to the normal. CONCLUSION: Although the cerebellum decreased in size with age, the pons maintained its size up to eighth' decades. The measurement of middle cerebellar peduncle on axial plane (C) and the ratio of basis pontis on midsagittal plane (F/G) were important in the evaluation of OPCD and WallerJan degeneration, respectively.
Cerebellum* ; Humans ; Magnetic Resonance Imaging* ; Pons*

PURPOSE: This study was to determine the effect of oral vitamin C supplements on blood sugar and antioxidative status in Types II diabetes mellitus patients. METHOD: Data for the study were collected from June 24 to August 31, 2001. Participants(31) took 1g/day vitamin C for 4 weeks, after a 1 - week taking no Vitamin C, followed by Vitamin C 3g/day for 4 weeks. A baseline blood sample was obtained following a 12hour overnight fast and at the end of each 4week Vitamin C administration. Blood samples were taken for plasma vitamin C concentration, fasting blood sugar, HbA1c, superoxide scavenging activity and hydrogen peroxide scavenging activity. The data were analyzed by SPSS for repeated measures ANOVA. RESULT: Plasma vitamin C concentration was significantly increased over dose(F=3.316, p=.043). Fasting blood sugar and HbA1c was significantly decreased over dose(F=13.192, p=.000; F=11.995, p=.000). Superoxide scavenging activity and hydrogen peroxide scavenging activity was significantly increased over dose(F=486.138, p=.000; F=177.704, p= .000). CONCLUSION: The results suggest that megadose vitamin C supplementation may have a beneficial effect in diabetes mellitus patients on both glycemic control and antioxidant status. Thus dietary measures to increase plasma vitamin C may be an important health strategy for reducing the compliance of diabetic patients.

Proliferations of the endometrial glands form a continuum from focal glandular crowding through simple hyperplasia, complex hyperplasia and atypical hyperplasia to frank adenocarcinoma. But objective criteria to distinguish these proliferative endometrial lesions are not clear-cut and terminology is confusing. The p53 protein is a nuclear phosphoprotein that can regulate cell proliferation and suppress tumor growth. Mutation in the p53 gene have been reported in a variety of human tumors, and in selected malignancies overexpression of p53 has been associated with poor prognosis. In this study we examined a series of endometrial proliferative lesion, including hyperplasia, adenocarcinoma, and adenomyosis to determine whether or not p53 is overexpressed in these lesions. In the result, p53 immunoreactivity was observed in 3 of 17 (17.6%) simple hyperplasia, one of 6 (16.6%) complex hyperplasia, none of 3 (O%) atypical hyperplasia, 6 of 13 (46.1%) adenocarcinoma and none of 10 (O%) adenomyosis. In conclusion, p53 mutation seems to play a role in oncogenesis of endometrial adenocarcinoma in early phase but there was no significant relationship between p53 overexpression and histologic grade of adenocarcinoma.
Adenocarcinoma* ; Adenomyosis ; Carcinogenesis ; Cell Proliferation ; Crowding ; Endometrial Hyperplasia* ; Female ; Genes, p53 ; Humans ; Hyperplasia ; Prognosis

PURPOSE: The purpose of this study was to develop an instrument to measure breastfeeding empowerment for the Korean mother, and to test the validity and reliability of the instrument. METHOD: The items of instruments used was based on literature review. Nineteen item scales were developed with five domains. In order to test reliability and validity of the scale, data was collected from 99 mothers who were within 4weeks, postpatum and 88 mothers who had had children within 1 year. Data was collected between September 2nd and 24th by a self-reported questionnaire. RESULT: The results were as follows: As a result of factor analysis three times, 19 items were selected from the total of 24 items. Five factors evolved by factor analysis, which explained 65.7% of the total variance. The first factor 'breastfeeding skill' explained 34.1%, the 2nd factor 'group empowerment' 10.6%, the 3rd factor 'breastfeeding will' explained 7.8%, the 4th factor 'social policy empowerment' 7.0%, and the 5th factor 'adherence to exclusive breastfeeding' 6.2%. Cronbach's alpha coefficient of this scale was .8781. CONCLUSION: The study supports the reliability and validity of the scale. Because the main concept of breastfeeding empowerment was breastfeeding skill, there were distinct differences in the dimensions of breastfeeding empowerment scales.
Breast Feeding* ; Child ; Humans ; Mothers ; Power (Psychology)* ; Surveys and Questionnaires ; Reproducibility of Results ; Weights and Measures

PURPOSE: The study was performed to identify exercise self-efficacy, depression, and stress by the stage of change in exercise behavior in middle aged women. METHOD: The subjects consisted of 317 women residing in B city by convenience sampling. The collected data was analyzed by the SPSS/WIN program. RESULT: The subjects were distributed in each stage of exercise behavior change: There were 53 subjects in the pre-contemplation stage, 86 subjects in the contemplation stage, 88 subjects in the preparation stage, 51 subjects in the action stage and 39 subjects in the maintenance stage. Analysis of variance showed that exercise self-efficacy (F=39.9, p< .001), depression (F=5.58, p< .001), and stress (F=6.33, p< .001) were significantly associated with the stages of exercise behavior change. There was a significant negative correlation between the stage of change and depression, and the stage of change and stress, but a significant positive correlation between the stage of change and self- efficacy, depression and stress. CONCLUSION: This study identified that exercise self-efficacy, depression and stress were significant variables to explain a possible relationship with exercise stages of middle aged women. This study provides new information to influence the development of better health promotion and exercise intervention for middle aged women in the community.
Depression* ; Female ; Health Promotion ; Humans ; Middle Aged* ; Self Efficacy*