By using (99m)Tc-Pertechnetate, we evaluated the thyroid function of 136 persons with uptake slopeindex(U.S.I.) which was calculated by computerized dynamic flow study. Also, we compared our results of U.S.I.with those of established ¹³¹I-24 hr uptake % in given materials by comparative analysis of their correlation with the hormonal values of T3, T4, Free T4. The results wre as follows: 1. The U.S.I. of euthyroidismal group and hyperthyrodismal group were 4.87±2.26, 27.67±9.56 respectively. The ¹³¹I-24 hr uptake % of above groups were29.22±10.23, and 71.45±15.51. So the differentiation of the two groups could be done more easily by using (99m)Tc-Pertenchnetate U.S.I. than by using ¹³¹I-24 hr uptake %. 2. The correlation rates between (99m)Tc-Pertechnetate U.S.I. and other laboratory hormon levels, T3, T4, Free T4, ar almost parallel with thosebetweeen ¹³¹I-24 hr uptake % and the values of T3, T4, Free T4. Also the direct correlation rate between (99m)Tc-Pertechnetate U.S.I. and ¹³¹I-24 hr uptake % was 0.898. So, the method of thyroidal function evaluation by (99m)Tc-Pettechnetate U.S.I. is very reliable. 3. The (99m)Tc-Pertechnetate U.S.I. is very helpful to evaulate thefunctions of each lobe respectively incases of having obviously different radioactivity between both lobes. 4. (99m)Tc-Pertechnetate used dynamic thyroid function study and scan can be performed during the short time without preparation and especially helpful in debilitating patient and patients under antithyroid drug therapy, who need repetitive follow-up examination.
Drug Therapy ; Follow-Up Studies ; Humans ; Methods ; Radioactivity ; Thyroid Gland

PURPOSE: This study was intended to present basic data of a more effective drug free education program by examining and analyzing the needs of drug and health education in the adolescent. METHOD: The study subjects were 480 students from six high schools in Pusan. The data were collected by a self-administered questionnaire between June 1 and June 10, 1999. Descriptive statistics, t-test, one-way ANOVA, Scheffe test in SPSS program were used for data analysis. RESULT: The scoring rate of knowledge for drug abuse of the subjects was 26.8%. For the scores of knowledge according to the type of drug, cigarettes were the highest at 38.4%, and for the scores of knowledge according to items, the abuse part was 59%, also the highest. The needs of drugs and drug education for the subjects had an average of 19.59. For the score of needs according to the items, plans to maintain and improve health was 1.72, the highest, methods to control anger and stress was 1.66, toxicity of drugs was 1.51, and medicinal use of drugs was 1.44.For the characteristics of the subject and characteristics relating to drugs, and the comparison of needs of drug education, consisted of students who said they liked or disliked their school life, those who have had drug education at school, who having received drug education by various kinds of materials, all had high needs for the education. CONCLUSION: It is necessary that drug free education plans including plans to maintain and improve health on the basis of the needs of drug education for the adolescent and other contents such as the methods to control anger and stress are established. Development of various kinds of audio-visual materials, publicity booklets and educational programs for parents etc. are needed in order to make the adolescent have an interest in drug free education, and recognize its importance.
Adolescent* ; Anger ; Busan ; Education* ; Health Education ; Humans ; Pamphlets ; Parents ; Statistics as Topic ; Substance-Related Disorders ; Tobacco Products ; Child Health

PURPOSE: The purpose of this study was to predict the risk factors for vascular complications among patients with type 2 diabetes. METHOD: The data were collected from August to September, 2007 using clinical examination and questionnaires. Patients (N=101) were recruited from the endocrinology department of P University hospital in D city. Descriptive statistics, Pearson correlation coefficients and multiple linear regression were used to analyze the data. RESULTS: The cardiovascular risk of patients with diabetes was significantly related to self care behavior, family history, and smoking status. The risk of peripheral vascular complications was not related to predictors included in the study. With multivariate analyses, significant predictors of cardiovascular risk for these patients were self care behavior, family history, and smoking status (R2=.40, p<.0001). CONCLUSION: The findings of this study indicate that smoking cessation and improving self-care behavior are essential to reduce the risk of cardiovascular complications among patients with diabetes. To enhance self-care practices for the patients with diabetes, nursing interventions, such as telephone counseling, problem focused nursing counseling, and peer group activities should be considered.
Counseling ; Diabetes Complications ; Diabetes Mellitus ; Endocrinology ; Humans ; Linear Models ; Multivariate Analysis ; Peer Group ; Surveys and Questionnaires ; Risk Factors ; Self Care ; Smoke ; Smoking ; Smoking Cessation ; Telephone

This study was conducted with 512 students in 4 primary schools located at the inner and the outskirt of K city, Northern Kyungsang Province from November 6, 2001 to November 27, 2001(during 3 weeks). This study was a research about the difference of a bullying degree and tendency of both teasing and teased students. The purpose of the study was to help nursing teachers in charge of student consultation and treatment. The findings are as follows. First, for to whom students confess their worries, students in lower grade talked to their parents while students in higher grade talked to their close friends. The higher grader, the higher rate in solving their problems by themselves. For how many students are teased by their peers in groups, 52.0% students answered 1 or 2 students in a class. For the reasons of bully, 37.0% higher graders answered, very selfish and putting on airs after 29.6% lower graders answered, ugly and bad at speaking. Second, for perception of peer relation, 81.3% students participating in the study answered, very important. For a question whether students satisfy present relation with their friends by gender, 53.7% boys were satisfied while 34.6% girls were satisfied. Third, for difference in bullying by gender, boys mainly teased others by using words and physical power(p < 0.000) while girls estranged others. When it goes to teased students, it was the case: boys were bullied physically(p < 0.000) and linguistically while girls were hurt by estrangement. Having nothing direct to do with school achievement, nursing teacher should make good use of such an advantage that students tend to easily confess their worries to them and take care of psychological aspects of students in treatment. Furthermore, it needs to include contents of bully in the regular heath care education.
Bullying* ; Education ; Female ; Friends ; Humans ; Nursing ; Parents ; Child Health

PURPOSE: This study was attempted to find out the actual conditions of drug education among the elementary school teachers. METHOD: 468 teachers consists of nurse-teachers 175, class-room teachers 240 and athletics teachers 53 of the elementary schools in Pusan city were subjected for this study. The period was December 23th through December 28th, 2002 and collected data was analyzed by SPSSWIN program using frequency, percentage, mean, standard deviation and ANOVA. RESULT: The results of this study were as follows: 1. The average point of nurse-teachers performance(2.11) was higher than that of class-room teachers(1.37) and athletic teachers(1.56). 2. Practical difficulties of drug education was no system in the curriculum for nurse-teachers(22.9%), insufficient expert knowledge for class-room teachers(26.3%) and a lack of education materials for athletics teachers(37.7%). For more effective drug education, 25.7% of nurse-teachers hope to have more organized curriculum presentations, class-room teachers(24%) and athletics teachers(22.7%) hope that more various education materials will be developed. CONCLUSION: Based on this results, drug education contents is needed to supplement a drug use prevention program.
Busan ; Curriculum ; Education* ; Hope ; Humans ; Sports ; Child Health

No abstract available.
Estrogens* ; Humans* ; Pituitary Neoplasms* ; Receptors, Estrogen*

Hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome is a rare autosomal recessive urea cycle disorder. HHH is caused by a deficiency of the mitochondrial ornithine transporter protein, which is encoded by the solute carrier family 25, member 15 (SLC25A15) gene. Recently, government supported Korean newborn screening has been expanded to include a tandem mass spectrometry (MS/MS) measurement of ornithine level. We report a case of a neonate with HHH syndrome showing a normal MS/MS measurement of ornithine level. A female newborn was admitted to neonatal intensive unit due to familial history of HHH syndrome. Her parents were consanguineous Parkistani couple. The subject's older sister was diagnosed with HHH syndrome at age of 30 months based on altered mental status and liver dysfunction. Even though the subject displayed normal ammonia and ornithine levels based on MS/MS analysis, a molecular test confirmed the diagnosis of HHH syndrome. At 1 month of age, amino acid analysis of blood and urine showed high levels of ornithine and homocitrulline. After 11 months of follow up, she showed normal growth and development, whereas affected sister showed progressive cognitive impairment despite no further hyperammonemia after protein restriction and standard therapy. Our report is in agreement with a previous Canadian study, which showed that neonatal samples from HHH syndrome patients demonstrate normal ornithine levels despite having known mutations. Considering the delayed rise of ornithine in affected patients, genetic testing, and repetitive metabolic testing is needed to prevent patient loss in high risk patients.

PURPOSE: To determine the patterns of evaluation and treatment in the patient with early breast cancer treated with conservative surgery and radiotherapy and to improve the radiotherapy techiniques, nationwide survey was performed. MATERIALS AND METHODS: A web-based database system for Korean Patterns of Care Study (PCS) for 6 common cancers was developed. Two hundreds sixty-one randomly selected records of eligible patients treated between 1998~999 from 15 hospitals were reviewed. RESULTS: The patients ages ranged from 24 to 85 years(median 45 years). Infiltrating ductal carcinoma was most common histologic type (88.9%) followed by medullary carcinoma (4.2%) and infiltrating lobular carcinoma (1.5%). Pathologic T stage by AJCC was T1 in 59.7% of the casses, T2 in 29.5% of the cases, Tis in 8.8% of the cases. Axillary lymph node dissection was performed in 91.2% of the cases and 69.7% were node negative. AJCC stage was 0 in 8.8% of the cases, stage I in 44.9% of the cases, stage IIa in 33.3% of the cases, and stage IIb in 8.4% of the cases. Estrogen and progesteron receptors were evaluated in 71.6%, and 70.9% of the patients, respectively. Surgical methods of breast-conserving surgery was excision/lumpectomy in 37.2%, wide excision in 11.5%, quadrantectomy in 23% and partial mastectomy in 27.5% of the cases. A pathologically confirmed negative margin was obtained in 90.8% of the cases. Pathological margin was involved with tumor in 10 patients and margin was close (less than 2 mm) in 10 patients. All the patients except one recieved more than 90% of the planned radiotherapy dose. Radiotherapy volume was breast only in 88% of the cases, breast+supraclavicular fossa (SCL) in 5% of the cases, and breast+SCL+posterior axillary boost in 4.2% of the cases. Only one patient received isolated internal mammary lymph node irradiation. Used radiation beam was Co-60 in 8 cases, 4 MV X-ray in 115 cases, 6 MV X-ray in 125 cases, and 10 MV X-ray in 11 cases. The radiation dose to the whole breast was 45~9.4 Gy (median 50.4) and boost dose was 8~20 Gy (median 10 Gy). The total radiation dose delivered was 50.4~70.4 Gy (median 60.4 Gy). CONCLUSION: There was no major deviation from current standard in the patterns of evaluation and treatment for the patients with early breast cancer treated with breast conservation method. Some varieties were identified in boost irradiation dose. Separate analysis for the datails of radiotherapy planning will be followed and the outcome of treatment is needed to evaluate the process.
Breast Neoplasms ; Breast* ; Carcinoma, Ductal ; Carcinoma, Lobular ; Carcinoma, Medullary ; Estrogens ; Humans ; Korea* ; Lymph Node Excision ; Lymph Nodes ; Mastectomy, Segmental* ; Radiotherapy