No abstract available.
Breast Neoplasms* ; Breast* ; Cyclin D1* ; Cyclins* ; Survival Rate*

PURPOSE: The purpose of this study was to investigate the effects of self-efficacy, social support, and depression in elementary school children. METHODS: The participants of this study were 619 students from seven elementary schools located in Jollabuk-do Province, Korea. The methods included data analysis, descriptive statistics, t-test, ANOVA, Scheffe test, Pearson's correlation coefficients and stepwise multiple regression using SPSS/WIN version 15.0. RESULTS: The mean scores of self-efficacy, social support, and depression were 2.9+/-0.58, 3.2+/-0.44 and 14.0+/-7.32, respectively. There was a significant positive correlation between self-efficacy and social support (r=.517, p<.001). Significant negative correlations were observed between self-efficacy and depression (r=-.557, p<.001) and between social support and depression (r=-.571, p<.001). The variables of depression in elementary school children were self-efficacy and social support, which explained 42.7% of the cases. CONCLUSION: The findings from this study suggest that current intervention programs are not sufficient to curb depression in elementary school children and therefore it is needed to develop nursing intervention programs to promote self-efficacy and social support.
Child* ; Depression* ; Humans ; Korea ; Nursing ; Self Efficacy ; Statistics as Topic

PURPOSE: The purpose of this study was to propose and to test a predictive model that could explain and predict the health promotion behavior of obese school-age children in Korea. METHODS: Participants for this study were 365 students from 13 elementary schools located in Jeonbuk Province, Korea. The data were analyzed using SPSS 15.0 program and Amos 7.0 program. RESULTS: The results verified the factors that influence health promotion behavior of the participants. Important direct factors were prior health-related behavior, perceived self-efficacy, and commitment to a plan of action and indirect factors were perceived barrier and activity-related effect. These factors explained 75.3% of variance in the participants' health promotion behavior. The proposed model was concise and extensive in predicting health promotion behavior of the participants. CONCLUSION: Findings may provide useful assistance in developing effective nursing interventions for maintaining and promoting health promotion behavior in obese school-age children.
Attitude to Health ; Child ; Child Behavior ; Female ; *Health Promotion ; Humans ; Male ; *Models, Statistical ; Obesity/*prevention &control/psychology ; Questionnaires ; Self Efficacy ; Social Support

The diagnosis of soft tissue osteochondroma should be considered when a well-defined osseous mass is located in the soft tissues. The differential diagnosis includes myositis ossificans, tumoral calcinosis, synovial chondromatosis, and soft tissue osteosarcoma, true osteochondroma which arises from bone. One case of soft tissue osteochondroma in the knee, a lesion of uncertain pathogenesis is reported.
Calcinosis ; Chondromatosis, Synovial ; Diagnosis ; Diagnosis, Differential ; Knee ; Myositis Ossificans ; Osteochondroma* ; Osteosarcoma

Herein we wish to report a case of pernicious anemia and myasthenia gravis occurred after treatment with removal of an invasive thymoma and irradiation. Nine years ago, the male patient was visited due to chest pain, and was found a mediastinal mass at his age of 55. He received open thoracotomy and was found stage III invasive thymoma which infiltrated phrenic nerve and pericardium. After removal of thymoma, he received 4,500cGy of radiation. Two years later, he complained of left eyelid drooping and diagnosed as myasthenia gravis with tensilon test. His myasthenic eye symptom was controled with Mestinon. After 9 years from thymectomy, he complained of dizziness and dyspnea on exertion. Bone marrow smear revealed megaloblastic anemia and serum vitamin B12 level was 42.24pg/ml. Gastric juice analysis revealed achlorhydria with positive anti-intrinsic factor antibody. 6 weeks after treatment with parenteral vitamin B12, hematologic findings were normalized.
Achlorhydria ; Anemia, Megaloblastic ; Anemia, Pernicious* ; Bone Marrow ; Chest Pain ; Dizziness ; Dyspnea ; Edrophonium ; Eyelids ; Gastric Juice ; Humans ; Male ; Myasthenia Gravis* ; Pericardium ; Phrenic Nerve ; Pyridostigmine Bromide ; Thoracotomy ; Thymectomy* ; Thymoma* ; Vitamin B 12

PURPOSE: The purpose of this research was to determine the effects of a safety management program on safety accident-related knowledge, attitude and behavior of elementary school students in Korea. METHODS: This study adopted nonequivalent control group pretest-posttest design. The number of subjects was 34 in the experimental group and 31 in the control group. The safety management program was performed for approximately 50 minutes each session, once a week for 8 weeks. Data were collected from March 14th to June 23th, 2006, and analyzed by chi2 test and independent t-test with SPSS WIN 16.0. RESULTS: There were statistically significant differences in safety-related knowledge (t=3.010, p=.006) and behavior (t=18.833, p=.001) between the experimental group and the control group. The score of attitude was different between the experimental group and the control group but the difference was not statistically significant. CONCLUSION: The safety management program used in this study was appropriate for elemental school students and affected safety-related knowledge and behavior of elementary school students. Therefore safety education should be provided systematically for elementary schools over the whole country.
Accident Prevention ; Education ; Humans ; Korea* ; Safety Management*

PURPOSE: The purpose of this qualitative research is to explore the background of occurrence of perceived incivility by nursing students in clinical practice.METHOD: Data were collected through focus interviews and individual interviews were analysed using qualitative content analysis.RESULT: The results showed that three categories that represented the background of occurrence of incivility were scheme which is not cleared, position which is not settled and unequal relationship.CONCLUSION: Since the background of occurrence of perceived incivility is complex, So it is required to macroscopic approach to reduce the perceived incivility of the students in the clinical practice.
Humans ; Methods ; Nursing ; Qualitative Research ; Students, Nursing

PURPOSE: This study was to examine the effects of Taping therapy on the deformed angle of the foot and pain in hallux valgus patients. METHOD: The subjects were 24 feet from 15 patients who were diagnosed withhallus valgus at the orthopedic department of K University Hospital in Seoul. Taping therapy was conducted 15 times overall during a four-week period. Data was analyzed using descriptive statistics and t-test. RESULT: The deformed angle of the foot of the hallus valgus patients significantly improved from 21.95(4.38) to 18.75(4.80) after Taping therapy. Pain significantly decreased from 4.73(1.56) to 3.45(2.21) after Taping therapy. CONCLUSION: The result shows that Taping therapy is effective in improving the deformed angle of the foot and in decreasing pain in the hallux valgus patients.
Adult ; Female ; Hallux Valgus/*therapy ; Humans ; Middle Aged ; *Orthotic Devices ; Pain

Autoimmune diseases (AIDs), a heterogeneous group of immune-mediated disorders, are a major and growing health problem. Although AIDs are currently treated primarily with anti-inflammatory and immunosuppressive drugs, the use of stem cell transplantation in patients with AIDs is becoming increasingly common. However, stem cell transplantation therapy has limitations, including a shortage of available stem cells and immune rejection of cells from nonautologous sources. Induced pluripotent stem cell (iPSC) technology, which allows the generation of patient-specific pluripotent stem cells, could offer an alternative source for clinical applications of stem cell therapies in AID patients. We used nonintegrating oriP/EBNA-1-based episomal vectors to reprogram dermal fibroblasts from patients with AIDs such as ankylosing spondylitis (AS), Sjögren's syndrome (SS) and systemic lupus erythematosus (SLE). The pluripotency and multilineage differentiation capacity of each patient-specific iPSC line was validated. The safety of these iPSCs for use in stem cell transplantation is indicated by the fact that all AID-specific iPSCs are integrated transgene free. Finally, all AID-specific iPSCs derived in this study could be differentiated into cells of hematopoietic and mesenchymal lineages in vitro as shown by flow cytometric analysis and induction of terminal differentiation potential. Our results demonstrate the successful generation of integration-free iPSCs from patients with AS, SS and SLE. These findings support the possibility of using iPSC technology in autologous and allogeneic cell replacement therapy for various AIDs, including AS, SS and SLE.
Autoimmune Diseases* ; Fibroblasts ; Humans ; In Vitro Techniques ; Induced Pluripotent Stem Cells* ; Lupus Erythematosus, Systemic ; Pluripotent Stem Cells ; Spondylitis, Ankylosing ; Stem Cell Transplantation ; Stem Cells ; Transgenes

Copy number variation has been associated with various autoimmune diseases. We investigated the copy number (CN) of the DEFA1 gene encoding alpha-defensin-1 in samples from Korean individuals with Behcet's disease (BD) compared to healthy controls (HC). We recruited 55 BD patients and 35 HC. A duplex Taqman(R) real-time PCR assay was used to assess CN. Most samples (31.1%) had a CN of 5 with a mean CN of 5.4 +/- 0.2. There was no significant difference in the CN of the DEFA1 gene between BD patients and HC. A high DEFA1 gene CN was significantly associated with intestinal involvement in BD patients. Variable DEFA1 gene CNs were observed in both BD patients and HC and a high DEFA1 gene CN may be associated with susceptibility to intestinal involvement in BD.
Adult ; Behcet Syndrome/*complications/*genetics ; Female ; Gene Dosage ; Genetic Predisposition to Disease ; Genotype ; Humans ; Intestinal Diseases/*etiology/*genetics ; Male ; Middle Aged ; Real-Time Polymerase Chain Reaction ; alpha-Defensins/*genetics