Hepatitis G virus (HGV) is a single-strand RNA virus in the Flaviviridae family, it was recently identified from the plasma of a patient with chronic hepatitis. HOV infection may cause acute and chronic liver disease by blood transfusion, drug addicts, hemophilia, and multiple sexual partners. But clinical significance of infectious pathway is still unclear. In this report, we amplified HGV RNA by reverse transcription-PCR (RT-PCR) by primers within the highly conserved 5'-noncoding region (NCR) and used restriction fragment length polymorphism (RFLP) method for the polymorphism analysis of amplified HGV gene. HGV was shown to be present in 7 of 78 (9.0%) from HCV RT-PCR positive serum samples and 5 of 58 (8.6%) from HCV RT-PCR negative serum samples. From the RFLP method HGV divided into four genotypes in 12 positive samples. Therefore, HGV genotype was distributed at least four different types in Korea.
Blood Transfusion ; Drug Users ; Flaviviridae ; GB virus C* ; Genotype ; Hemophilia A ; Hepatitis* ; Hepatitis, Chronic ; Humans ; Korea ; Liver Diseases ; Plasma ; Polymorphism, Restriction Fragment Length* ; RNA ; RNA Viruses ; Sexual Partners

The mutation of p53, a tumor suppressor gene, has been considered to play an important role in tumorigenesis in a variety of human cancers and the abnormal expression of p53 are frequently associated with poor prognosis. In order to examine the association of p53 overexpression with known prognostic factors including estrogen receptors (ER) and progesterone receptors (PR), we studied the status of p53 protein expression by immunohistochemical staining of paraffin sections of 29 endometrial carcinoma (25 endometrioid carcinoma, 2 clear cell carcinoma, and 2 serous carcinoma), obtained from hysterectomy. The results were as follows: The expression of p53, ER, and PR was present in 9/29 (31%), 3/29 (16%), and 12/29 (48%), respectively. The expression of p53 in endometrioid adenocarcinoma was present in 6/25 (24%) and showed significant correlation with histologic grade, nuclear grade, and myometrial invasion. The status of PR showed significant inverse correlation with histologic grade, nuclear grade and myometrial invasion. There was no significant correlation between ER status and these histologic factors. The expression of p53 was inversely associated with the status of PR, but statistically not significant. Our results indicate that p53 may be useful in predicting prognosis in endometrial carcinoma and will be able to provide helpful information in predetermination of aggressive behavior of the tumor in evaluation of curettage specimen.
Carcinogenesis ; Carcinoma, Endometrioid ; Curettage ; Endometrial Neoplasms* ; Female ; Genes, Tumor Suppressor ; Humans ; Hysterectomy ; Paraffin ; Prognosis ; Receptors, Estrogen ; Receptors, Progesterone

PURPOSE: This research was for checking the effect of meridian massage on the reduction of pain and subjective symptoms of myofascial pain syndrome. METHOD: The method of the research was interruptive time series design. The research objects are 25 hospital workers with myofascial pain syndrome at B hospital in Busan from July 22. 2002 to August 18, 2002. SPSS Win 10.0 was used for data analysis, paired t-test and repeated measures ANOVA for hypothesis test. RESULT: The recipients of meridian massage felt less pain than before(F=12.587, p=.000). The recipients of meridian massage felt less often than before (F=6.705, p=.001). The recipients of meridian massage got lower score on subjective symptoms of myofascial pain than before(F=12.857, p=.000). The recipients of meridian massage had lower blood pressure than before(systolic blood pressure: t=4.697, p=.000, diastolic blood pressure: t=3.426, p=.002). The recipients of meridian massage did not get the lower number of pulse than before(t=0.33, p=.744). CONCLUSION: The above results show that meridian massage is effective on the reduction of pain and subjective symptoms of myofascial pain syndrome and makes stable the blood pressure. Therefore meridian massage can be apply as the effective intervention for the reduction of pain and subjective symptoms of myofascial pain syndrome.
Blood Pressure ; Busan ; Massage* ; Myofascial Pain Syndromes* ; Statistics as Topic

Carcinoma, Squamous Cell ; Diagnosis ; Epithelium ; Humans ; Jaw ; Mandible ; Mandibular Osteotomy ; Middle Aged ; Mouth Mucosa ; Myocutaneous Flap ; Odontogenic Cysts

No abstract available.
Child* ; Humans

INTRODUCTION: Osteoporosis, the most common metabolic bone disorder, is a condition of reduced bone density and increased susceptibility to fractures. Osteoporosis is a major public health problem and a significant cause of morbidity in postmenopausal women. Therefore family physicians as primary care physicians are in a key position for preventing and treating this disorder. So we studied the factors affecting to bone mineral density in postmenopausal women. MATERIALS AND METHODS: A total of 136 spontaneous postmenopausal women were participated in the study. They have measured spinal bone mineral density by dual energy x-ray absorptiometry from January 1992 to June 1995 at Yeungnam University Hospital. Age, height, weight, age at menarche and menopause, number of child and breast feeding child, history of oral pill ingestion, family history of osteoporosis, amount of milk and coffee ingestion, consumption of tobacco and alcohol and physical activity were assessed by qustionnaire and medical records. RESULTS: physical activity and weight were significant contributors. Physical activity is most the largest contributor. CONCLUSIONS: Among factors affecting to BMD in postmenopausal women, physical activity and weight were more important factors. Therefore continuous physical activity is significant factor to prevent osteoporosis in postmenopausal women.
Absorptiometry, Photon ; Bone Density* ; Breast Feeding ; Child ; Coffee ; Eating ; Female ; Humans ; Medical Records ; Menarche ; Menopause ; Motor Activity ; Osteoporosis ; Physicians, Family ; Physicians, Primary Care ; Public Health ; Tobacco

PURPOSE: The purpose of this study was to investigate the effects of self-efficacy, social support, and depression in elementary school children. METHODS: The participants of this study were 619 students from seven elementary schools located in Jollabuk-do Province, Korea. The methods included data analysis, descriptive statistics, t-test, ANOVA, Scheffe test, Pearson's correlation coefficients and stepwise multiple regression using SPSS/WIN version 15.0. RESULTS: The mean scores of self-efficacy, social support, and depression were 2.9+/-0.58, 3.2+/-0.44 and 14.0+/-7.32, respectively. There was a significant positive correlation between self-efficacy and social support (r=.517, p<.001). Significant negative correlations were observed between self-efficacy and depression (r=-.557, p<.001) and between social support and depression (r=-.571, p<.001). The variables of depression in elementary school children were self-efficacy and social support, which explained 42.7% of the cases. CONCLUSION: The findings from this study suggest that current intervention programs are not sufficient to curb depression in elementary school children and therefore it is needed to develop nursing intervention programs to promote self-efficacy and social support.
Child* ; Depression* ; Humans ; Korea ; Nursing ; Self Efficacy ; Statistics as Topic

No abstract available.
DNA*

BACKGROUND: The purpose of this study was to examine the frequency and characteristics of needlestick/sharps injuries (NSIs) in nursing students in Korea. METHODS: The study was based on a survey of questionnaires completed by 341 nursing students who had sustained at least one NSI during clinical practice in hospitals. RESULTS: The NSI incidence rate was 36.4%. Approximately half of the students reported two to four NSIs. Most (90.2%) of the NSIs occurred on the fingertips and were caused by a hollow-bore needle (46.8%) or lancet (45.8%). Some students were exposed to used needles contaminated with unknown pathogens (37.3%), HBs Ag (2.3%), Venereal Disease Research Laboratory (VDRL) (0.8%), or HIV (0.6%). Students cited the reason for injury as carelessness, inexperience, hastiness, or recapping. Almost two-thirds of students who reported having experienced an NSI knew about post-exposure treatment. However, only one-third of the students with NSIs completed an official report. CONCLUSION: Korean nursing students lack knowledge about injury prevention, report procedures, and treatment after NSI. A revised educational approach with emphasis on occupational risk, skill development, and injury reporting is necessary to prevent NSI and to ensure that students obtain post-exposure prophylaxis.
Dietary Sucrose ; HIV ; Humans ; Incidence ; Korea ; Needles ; Needlestick Injuries ; Post-Exposure Prophylaxis ; Sexually Transmitted Diseases ; Students, Nursing ; Surveys and Questionnaires

BACKGROUND: Benign paroxysmal positional vertigo (BPPV) is the most common peripheral vestibular disorder that often resolves spontaneously. It was long believed that the condition was caused by inorganic particles in the cupula of the posterior semicircular canal. Management of this condition includes medication, surgery, physical exercise and more recently particle repositioning maneuvers. Among the various therapies, exercise therapy (ET) reported by Brandt-Daroff was based on the theory of cupulolithiasis and is designed to treat BPPV through dispersion of the debris from the cupula. METHODS: Fifty four patients with BPPV were treated with ET to determine the effectiveness. Fifteen additional patients with BPPV were treated with only medication and served as a control group. RESULT: Forty eight of 54 cases (88.9%) treated with ET showed improvement after 2 weeks. With medication alone, 8 of the 15 cases (53.4%) showed improvement after 2 weeks. CONCLUSIONS: The most important benefit of this maneuver seemed to be more expedient recovery than that with medication alone.
Exercise ; Exercise Therapy* ; Humans ; Semicircular Canals ; Vertigo*