Purpose: This study aimed to systematically evaluate school-based suicide prevention programs for adolescents, focusing on their impact on suicide attempts, knowledge and attitudes about suicide, and help-seeking behaviors. Methods: A systematic review was conducted following PRISMA guidelines. Databases searched included PubMed, Cochrane Library, EMBASE, PsycINFO, CINAHL, KMBASE, KoreaMed, and ScienceON. Randomized controlled trials of school-based interventions for middle and high school students were included. The Risk of Bias 2.0 tool was used to assess study quality. Results: Out of 1,738 screened records, eight studies met the inclusion criteria. SOS (Signs of Suicide) and SEYLE (Saving and Empowering Young Lives in Europe) programs significantly reduced suicide attempts by 40% and 55%, respectively. Sources of Strength improved help-seeking behavior (ES=0.62, p<.001), though results were inconsistent across interventions. All programs enhanced knowledge and attitudes about suicide, but methodological limitations, such as variability in implementation and reporting, affected reliability. Conclusion School-based suicide prevention programs effectively reduce suicide attempts and improve awareness but show mixed results for help-seeking behaviors. Standardized, scalable interventions and rigorous evaluations are needed to enhance their impact.

Purpose: This study aimed to systematically evaluate school-based suicide prevention programs for adolescents, focusing on their impact on suicide attempts, knowledge and attitudes about suicide, and help-seeking behaviors. Methods: A systematic review was conducted following PRISMA guidelines. Databases searched included PubMed, Cochrane Library, EMBASE, PsycINFO, CINAHL, KMBASE, KoreaMed, and ScienceON. Randomized controlled trials of school-based interventions for middle and high school students were included. The Risk of Bias 2.0 tool was used to assess study quality. Results: Out of 1,738 screened records, eight studies met the inclusion criteria. SOS (Signs of Suicide) and SEYLE (Saving and Empowering Young Lives in Europe) programs significantly reduced suicide attempts by 40% and 55%, respectively. Sources of Strength improved help-seeking behavior (ES=0.62, p<.001), though results were inconsistent across interventions. All programs enhanced knowledge and attitudes about suicide, but methodological limitations, such as variability in implementation and reporting, affected reliability. Conclusion School-based suicide prevention programs effectively reduce suicide attempts and improve awareness but show mixed results for help-seeking behaviors. Standardized, scalable interventions and rigorous evaluations are needed to enhance their impact.

Purpose: This study aimed to systematically evaluate school-based suicide prevention programs for adolescents, focusing on their impact on suicide attempts, knowledge and attitudes about suicide, and help-seeking behaviors. Methods: A systematic review was conducted following PRISMA guidelines. Databases searched included PubMed, Cochrane Library, EMBASE, PsycINFO, CINAHL, KMBASE, KoreaMed, and ScienceON. Randomized controlled trials of school-based interventions for middle and high school students were included. The Risk of Bias 2.0 tool was used to assess study quality. Results: Out of 1,738 screened records, eight studies met the inclusion criteria. SOS (Signs of Suicide) and SEYLE (Saving and Empowering Young Lives in Europe) programs significantly reduced suicide attempts by 40% and 55%, respectively. Sources of Strength improved help-seeking behavior (ES=0.62, p<.001), though results were inconsistent across interventions. All programs enhanced knowledge and attitudes about suicide, but methodological limitations, such as variability in implementation and reporting, affected reliability. Conclusion School-based suicide prevention programs effectively reduce suicide attempts and improve awareness but show mixed results for help-seeking behaviors. Standardized, scalable interventions and rigorous evaluations are needed to enhance their impact.

Purpose: This study aimed to systematically evaluate school-based suicide prevention programs for adolescents, focusing on their impact on suicide attempts, knowledge and attitudes about suicide, and help-seeking behaviors. Methods: A systematic review was conducted following PRISMA guidelines. Databases searched included PubMed, Cochrane Library, EMBASE, PsycINFO, CINAHL, KMBASE, KoreaMed, and ScienceON. Randomized controlled trials of school-based interventions for middle and high school students were included. The Risk of Bias 2.0 tool was used to assess study quality. Results: Out of 1,738 screened records, eight studies met the inclusion criteria. SOS (Signs of Suicide) and SEYLE (Saving and Empowering Young Lives in Europe) programs significantly reduced suicide attempts by 40% and 55%, respectively. Sources of Strength improved help-seeking behavior (ES=0.62, p<.001), though results were inconsistent across interventions. All programs enhanced knowledge and attitudes about suicide, but methodological limitations, such as variability in implementation and reporting, affected reliability. Conclusion School-based suicide prevention programs effectively reduce suicide attempts and improve awareness but show mixed results for help-seeking behaviors. Standardized, scalable interventions and rigorous evaluations are needed to enhance their impact.

Apert's syndrome(acrocephalosyndactyly) is a rare congenital anomaly that is characterized by the combination of premature fusion of multiple cranial sutures primarily involving the coronal suture and severe symmetrical syndactyly of fingers and toes. Some patients of this syndrome have various abnormalities of the central nervous system. We experienced a case of Apert's syndrome with craniofacial malformations, symmetric syndactyly, occipital encephalocele and hypogenesis of corpus callosum. She had a oxycephalic head with small sized anterior fontanelle, elongated forehead, hypertelorism, down-slanting palpebral fissures, flattened nose, cleft palate, low set ears and short neck. A 5x3 cm sized scalp-covered soft mass protruded in the occipital area through defect of the occipital bone. MRI showed hypogenesis of corpus callosum, occipital encephalocele, dilatation of the lateral and the third ventricles. She also had hands and feet with symmetric syndactyly involved skin and soft tissue but not bones.
Central Nervous System ; Cleft Palate ; Corpus Callosum* ; Cranial Fontanelles ; Cranial Sutures ; Dilatation ; Ear ; Encephalocele* ; Fingers ; Foot ; Forehead ; Hand ; Head ; Humans ; Hypertelorism ; Magnetic Resonance Imaging ; Neck ; Nose ; Occipital Bone ; Skin ; Sutures ; Syndactyly ; Third Ventricle ; Toes

No abstract available.
Gestational Trophoblastic Disease*

OBJECTIVES: The trial was performed to obtain an unbiased comparison of the relative merits of endocervical and vaginal prostaglandin E2(PGE2) in the case of parous and nulliparous woman with favorable and unfavorable cervical features. This study was performed to determine the clinical usefullness of endocervical PGE2 comparing with the vaginal PGE2 in cervical ripening and induction of labor. METHOD: The randomized trial with 65 Participants was performed with sealed envelopes for parity and Bishop score (from March to september, 1998). PGE2 tablet(3mg Dinoprostone) was administrated intravaginally to the 32 pregnant women and endocervically to the 33 pregnant women every eight hours with maximum three times until the regular labor develped. RESULT: Outcomes of labor and delivery were clearly related to cervical score at trial entry. endocerval PGE2 had a more marked effect on cervical ripeness than did vaginal PGE2. There were no significant differences on age distribution, gestatioanal period, primiparity, cervical status, initial B-score in each group. There were no significant differences in cesarian section rate, fetal distress, uterine hyperstimulation, side effect and poor infant outcome between the groups The mean induction time was statistically shorter in cervical group with multiparous women than other group(p=0.0195). In the induction-active labor time, cervical with primi group was statistically shorter than other group(p=0.0245). Statistically significant differences were noted between the nulliparous woman and multiparous women in mean induction time, induction-active labor time, time to B-score 8. In the factor that effects induction-active labor, route was significantly better than other factor.(p=0.0001) CONCLUSION: edocervical PGE2 is more effctive than vaginal PGE2 in cervical ripening and induction of active labor. the endocervical PGE2 resulted in a significantly shorter induction to active labor time compared with vaginal PGE2 and has almost no side effect. Because differences in effectiveness between endocervical and vaginal PGE2 are marginal, preference of woman and clinicians can the choice between them.
Age Distribution ; Cervical Ripening ; Dinoprostone ; Female ; Fetal Distress ; Humans ; Infant ; Parity ; Pregnancy ; Pregnant Women

BACKGROUND: There are a few studies on the effects of job strain on the prevalence of sleep problems in the foreign countries. In Korea, it has not been studied till now. In this article, the combined effects of job strain, shift work and some life style on the prevalence of sleep proplems were studied among workers in middle aged men. METHODS: 998 cases were chosen from 1109 men who visited health screening center from October to November, 1999. Sleep problems were categorized to insomnia, sleep deprivation, daytime sleepiness and snoring on the base of result of factor analysis of 11 questions. Job strain was measured by 11 questions which developed by Karasek and Theorell. All data set were analyzed using Chi square test and multiple logistic regression analysis. RESULTS: The 4 sleep proplems were analyzed by multiple logistic regression analysis in relation to job strain, shift work, occupation, obesity, sedentary life style, smoking, drinking. Insomnia was increased significantly from highest job strain group(Odds ratio (OR:2.02)) and non exercise group(OR:2.05). In these groups, daytime sleepiness was increased significantly(OR=1.92 in the highest job strain group, OR=1.72 in non exercise group). Sleep deprivation was increased in the highest job strain group(OR=2.18), managers & clerks(OR:1.67) and non exercise group(OR:1.78). Snoring was increased from BMI(Body mass index)> OR =25(OR=1.77), BMI> OR =27(OR=2.80) and non exercise group(OR:1.87). CONCLUSION: In the highest job strain group, insomnia, sleep deprivation and daytime sleepiness was increased significantly. And sedentary life style increased all sleep problems.
Dataset ; Drinking ; Humans ; Korea ; Life Style* ; Logistic Models ; Male ; Mass Screening ; Middle Aged* ; Obesity ; Occupations ; Prevalence* ; Sleep Deprivation ; Sleep Initiation and Maintenance Disorders ; Smoke ; Smoking ; Snoring

PURPOSE: The aim of this study was to identify the experience of patients with liver cirrhosis. METHOD: This study was performed from march 2003 to June 2003. The participators were five men. Data collected through in-depth personal interviews, which were recorded and analysed according to the Colazzi's method. RESULT: Liver cirrhosis was classified into 20 themes, 70 formulated meaning, and 10 categories. The Result confirmed that the experience of liver cirrhosis patients were classified into 10 categories; unexpected change, limited daily living and role, difficult compliance with therapeutic regimen, unbelief so untreated with apathy, negative emotional change, lack of cause perception, self control, perceived family support, expectations for recovery and healing. CONCLUSION: We, cooperative researchers, realized that to reduce not only the days of hospital treatment and the economic loss, as well as the expenditure of insurance the importance of managing liver cirrhosis from early diagnosis and the physical, spiritual, social role in studying the patients who experience liver cirrhosis.
Apathy ; Compliance ; Early Diagnosis ; Health Expenditures ; Humans ; Insurance ; Liver Cirrhosis* ; Liver* ; Male ; Self Concept

BACKGROUND: This prospective phase II trial was performed to determine the efficacy and toxicity of mitomycin C, vinorelbine and cisplatin combination chemotherapy for patients with previously untreated stage IIIB or IV non-small cell lung cancer (NSCLC). METHODS: Between January 1999 and April 2001, 30 patients with chemotherapy- naive stage IIIB or IV NSCLC were entered into this study. Mitomycin C at a dose of 7 mg/m2, vinorelbine at a dose of 25 mg/m2 and cisplatin at a dose of 75 mg/m2 on day 1 and vinorelbine at a dose of 25 mg/m2 on day 8 were administered. This regimen was repeated every 4 weeks. RESULTS: 29 patients out of 30 patients were assessable. Among the assessable patients, 15 (51.7%) patients had a partial response. The median duration of response and survival was 22 weeks and 39 weeks, respectively. Grade 3 or 4 leukopenia and thrombocytopenia were observed in 28.3% and 4.7% of all the cycles, respectively. Nausea and vomiting of grade 3 occurred only in 2.4% of all the cycles. CONCLUSION: The regimen of mitomycin C, vinorelbine and cisplatin for non-small cell lung cancer is active against advanced NSCLC with tolerable toxicities.
Adult ; Aged ; Antineoplastic Combined Chemotherapy Protocols/*therapeutic use ; Carcinoma, Non-Small-Cell Lung/*drug therapy/pathology ; Cisplatin/*administration & dosage ; Dose-Response Relationship, Drug ; Female ; Human ; Lung Neoplasms/*drug therapy/pathology ; Male ; Middle Aged ; Mitomycin/*administration & dosage ; Treatment Outcome ; Vinblastine/*administration & dosage/*analogs & derivatives