Hydrocephalus is a common malformation of the central nervous system and its cause may be either congenital or acquired. The imbalance between CSF formation and absorption, obstruction of CSF pathways, impaired venous absorption, and over secretion of CSF results in excessive accumulation of the fluid in the ventricles, leading to hydrocephalus. Although ventriculo-peritoneal shunt is regarded as the main and definitive therapy for rapidly progressive hydrocephalus, shunts in newborns have a high failure rate and thus there have been a search for alternative non-invasive techniques. Acetazolamide is a carbonic anhy- drase inhibitor, which acts by reducing production of CSF in the choroid plexus. Admini- stration of acetazolamide will decrease the rate of CSF production, preventing progressive ventricular enlargement. We experienced three cases of neonatal hydrocephalus successfully treated by long-term administration of acetazolamide. Brief review and related literatures were also presented.
Absorption ; Acetazolamide* ; Carbon ; Central Nervous System ; Choroid Plexus ; Humans ; Hydrocephalus* ; Infant, Newborn ; Ventriculoperitoneal Shunt

The purpose of this study was to compare the anthropometry and nutrition knowledge, food behaviour and lifestyle of women college students with different obesity indexes. The subjects were 251 women college students who were randomly selected from Kunsan National University. The height, body weight, soft/lean mass, fat mass, percentage of body fat, and fat distribution were measured, and health-related lifestyle habits were evaluated based on questionnaires. The subjects were assigned to one of the following groups based on their Body Mass Index (BMI): underweight, normal weight and overweight. The results were as follows. Their body weight, soft/lean mass, fat mass, percentage of body fat, and fat distribution were significantly higher in the overweight subjects when compared to the underweight or normal weight subjects. Standard of living, self-recognition of health status and duration of exercise were significantly correlated with their BMIs. Self-satisfaction with body weight decreased as the BMI increased. Most subjects had poor habits such as skipping meals and lack of exercises. The overweight and the underweight groups skipped meals more frequently than the normal weight group. There were no significant differences in the scores on the nutritional knowledge and the dietary behaviour of the subjects with different BMIs. Therefore, proper nutritional education on regular meals and intervention are required if women college students are to have normal weights and healthy lifestyles.
Adipose Tissue ; Anthropometry* ; Body Height ; Body Mass Index ; Body Weight ; Education ; Exercise ; Female ; Humans ; Jeollabuk-do* ; Life Style* ; Meals ; Obesity ; Overweight ; Socioeconomic Factors ; Thinness ; Weights and Measures ; Surveys and Questionnaires

BACKGROUND: Pyoderma gangrenosum is a rare disease in which a painful nodule or pustule breaks down to form a progressive enlarging ulcer. Until now, only 8 cases of pyoderma gangrenosum have been reported in Korea. Therefore, we thought it necessary to perform a clinical analysis of pyoderma gangrenosum in Korea with a review of literature. OBJECTIVE: Our purpose was to find the clinical features of pyoderma gangrenosum in Korea. METHODS: Fourteen cases with pyoderma gangrenosum were investigated by reviewing medical records. Results There were 6 males and 8 females. The onset age was between 4 years and 65 years, and most(9 cases) had developed the condition between the ages of 20 and 60. Thirteen cases involved the extremities and 3 cases had whale body involvement, Seven cases(50%) had multiple lesions. All cases had pain at the lesional sites. Two cases were classified as the bullous type and the others were ulcerative in nature. The histological fmdings were non-specific. Dense inflarnmatory infiltrates composed of lymphocytes and predominant neutrophils were found in the epidermis and dermis associated with ulceration. Two cases were treated only with systemic steroids, and 2 cases with dapsone and steroids, 2 cases with colchicine and steroids, and 1 case with steroids, dapsone and colchicine. One case was treated with colchicine and anti-Tbc drug, 1 case with dapsone, 3 cases with antibotics, 1 case with the anti-Tbc drug and 1 case with anti-cancer drugs. Systemic disease was present in 5D% of the cases. The associated diseases were Behcets disease(3 cases), tuberculosis(2 cases), systemic lupus erythematosus(1 case), pancytopenia(1 case), iron deficiency anemia(1 case), acute leukemia(1 case), and colon adenoma(1 case). Recurrence developed in 2 cases and positive pathergy reactions were observed in 3 cases. CONCLUSION: Pyoderma gangrenosum was eccompanied with systemic disease in 50% of the cases and the most common therapeutic drugs were steroids. It is therefore impartant to detect the presence of any underlying disease and to treat this alongside pyoderma gangrenosum.
Age of Onset ; Colchicine ; Colon ; Dapsone ; Dermis ; Epidermis ; Extremities ; Female ; Humans ; Iron ; Korea ; Lymphocytes ; Male ; Medical Records ; Neutrophils ; Pyoderma Gangrenosum* ; Pyoderma* ; Rare Diseases ; Recurrence ; Steroids ; Ulcer ; Whales

The purpose of this study was to compare the body compositions and food behaviors of middle aged men with different obesity indices. The subjects were 62 middle aged men who lived Gunsan city. Heights, body weights, soft/lean masses, fat masses, percentages of body fat, and fat distributions were measured. Food habits and health-related lifestyle habits were evaluated based on questionnaires. The subjects were assigned to one of the following groups based on their percentage of body fat (%Fat); normal, overweight and obesity. The results were as follows: their heights, fat masses, percentages of body fat, WHR, RBW, BMI and fitness scores were significantly higher in the obese subjects when compared to the normal and overweight subjects. Self-perceptions of weight and desires of weight control were significantly related with their percents of Fat. The overweight and the obese groups skipped meals, ate supper out, ate snacks, smoked tobacco, and exercised less frequently than the normal group. There were no significant differences in the scores of the dietary habits and drinking of alcohol among the three groups. Therefore, proper nutritional education on regular meals and intervention is required if middle aged men want to be of normal weight and have healthy lifestyles.
Adipose Tissue* ; Body Composition* ; Body Height ; Drinking ; Education ; Food Habits ; Humans ; Jeollabuk-do* ; Life Style ; Male ; Meals ; Middle Aged* ; Obesity ; Overweight ; Self Concept ; Smoke ; Snacks ; Tobacco ; Weights and Measures ; Surveys and Questionnaires

This study examined the effect of self-perception of health and related factors of flood life and disease on health floods intakes among the middle aged(150 men and 159 women) in the Jeonbuk region. The health foods were classified into 4 groups including Chinese medicine(CM), toner foods(TF), nutritional supplements(NS), and other manufactured health foods supplements(MHFS). Differences of BMI and self-perception for body shape was that overweight was 30% in men and 24.5% in women on BMI, but conversely was 21.3% in men and 43.4% in women on self-perception for body shape. Men thought themselves more than normal weight, but women thought themselves less than normal weight for the criteria of normal weight. Consumption of CM was high in the overweight group on BMI and was a low in the overweight group on self-perception for bodyshape Men thought themselves better than women and those in their 40's thought better than those in their 50's on self perception of health status, and women were better than men on self-perception of food habits. The difference of health foods intakes according to the self-perception of health status and food habits was not significant. The points of food habits, food attitude and nutrition knowledge were 11.21 +/- 2.43, 68.18 +/- 15.56 and 15.53 +/- 1.59 in women and 10.49 +/- 2.71, 67.53 +/- 14.41, and 15.11 +/- 1.79 in men respectively. The points of all were higher for women than for men. Consumption of CM (p<0.01) and TF(p<0.01) were a low in groups that scored high points on nutrition knowledge. The points of climacteric symptoms were that men were 48.36 +/- 6.30 and woman were 46.43 +/- 6.70. Men thought themselves in good condition more than women(p<0.01), and those in their 40's thought themselves in good condition as opposed to those in their 50's in men(p<0.05). Consumption of TF and NS were high in the low points group on climacteric symptoms(p<0.01). Women were higher than men on morbidity, but men were more than women on cases of liver disease(p<0.01). Consumption of CM was high in the liver disease group(p<0.05), MHFS was high in the kidney disease group(p<0.05), TF and NS were hgih in the bone disease group(p<0.05) and NS was hgih in the endocrine disease group(p<0.05). People in their 40's were higher than those in their 50's in men on morbidity of cold(p<0.05), women were higher than men by about 2 times on constipation (p<0.01), those in their 40's were higher than those in their 50's in mein on gastritis(p<0.05). Consumption of NS was highest for those with diseases in respiratory organs and gastrointestinal tracts. This study suggests that nutritional education for the right recognition of self-perception of health status and food habits, and nutrition knowledge are needed to select for health floods. Consumption of health foods was different according to kinds of diseases. Thus, recognition of etiology, symptoms and dietetics of diseases is needed to select adequate health foods for diseases in middle age.
Asian Continental Ancestry Group ; Bone Diseases ; Climacteric ; Constipation ; Dietetics ; Education ; Endocrine System Diseases ; Female ; Floods ; Food Habits ; Gastrointestinal Tract ; Food, Organic* ; Humans ; Jeollabuk-do* ; Kidney Diseases ; Liver ; Liver Diseases ; Male ; Middle Aged* ; Overweight ; Self Concept*

This study examined health foods intakes and related variables among the middle aged(150 men and 159 women) in the Jeonbuk region. Health foods were classified into 4 groups including Chinese medicine(CM), toner foods(TF), vitamin or mineral supplements(VMS), and other manufactured health food supplements(MHFS). The number of people taking health foods were higher for those in their 50's than in their 40's. The consumption rate of TF in men was the highest among health foods, this result had significance. The reasons for taking health foods were recovery from fatigue, supplement of nutrients and making smooth body activity in general, but TF was used to increase of vigor. The consumption rate of health foods was a little different according to social-economic factors, namely, the consumption rate of CM was higher in people in rural than urban areas, those who graduated from middle school than university, blue color & self-employed as opposed to housewives and service workers, low level income than high level income, and Buddhism and no religion than Christian. The consumption rate had a correlation with the habits of smoking, alcohol drinking and exercise ; namely, the consumption rate of CM was higher than VMS and MHFS on smokers and alcohol drinkers. The more the frequency of exercise, the higher the consumption rate of TF, but the duration of the exercise was not correlated. This study suggests that middle aged people need nutritional education for the right recognition and selection of health foods and to consider the nature of each type of health foods.
Alcohol Drinking ; Asian Continental Ancestry Group ; Buddhism ; Education ; Fatigue ; Food, Organic* ; Humans ; Jeollabuk-do* ; Male ; Middle Aged* ; Smoke ; Smoking ; Vitamins

The purpose of this study was to investigate the change in food habits of girl students 1985 and 1998. A similar study had been conducted in 1985 and this study was carried in May, 1998 using the questionnaires. The subjects were 746 female students in middle school, high school and university students living in Jeonbuk region. The average score of food habit was 4.11+/-1.63 out of a possible 10. This aversge is lower than the 4.91 score in 1985, especially the score of university students lowered from 4.80 points to 3.52+/-1.58 points. The correlation coefficient between the score of food habit and standard of living, utilizing increase as compared with the 54.9% in 1985. The most preferred side-dish changed from fried food to Kimchi. The preference of snacks was not changed. Eating bread increased at breakfast but eating noodles increased at lunch. University students' lunch basket preparation ratio decreased from 32.6% to 3.3%, so they had more noodles at refectory than lunch basket. The reason for skipping breakfast did not changes, but skipping lunch changed from annoyance due to lunch basket preparation to lack of time and no appetite. Skipping supper was changed from missing time to weight control. Having supper at home decreased from 96.6% to 75.9%. Substitution food on no preparation of lunch basket was changed from bread to noodles. The preference for biscuits and snack did not changes but fewer students preferend bread and fried food. In order to improve the nutritional status of the girl students, they must establish good food habits, especially by eating 3 regular meals per day and balancing their diet they should also be notified that severe weight control is very harmful for health.
Appetite ; Bread ; Breakfast ; Diet ; Eating ; Female* ; Food Habits* ; Humans ; Jeollabuk-do* ; Lunch ; Meals ; Nutritional Status ; Snacks ; Socioeconomic Factors ; Surveys and Questionnaires

Problems of Adverse Drug Reaction (ADR) have been regarded as growing social concern in health. The purposes of this study were to analyze current domestic and foreign adverse drug reaction monitoring system and to develop a web-based reporting system and to test its performance. Two university hospitals, one clinic, and six pharmaceutical companies were participated in this pilot project. From March 1 to Oct. 30, 1998, a total of 310 cases were reported fromm the participating two hospitals. Of these, 240 cases were mild(77.42%), 61 cases were moderate(19.68%), and 9 cases were severe cases(2.9%). More ADR cases were report from the outpatients(83.22%) than inpatients. Oral intake was the most common route of administration(74.2%). A future ADR monitoring system was also presented in this paper.
Drug-Related Side Effects and Adverse Reactions ; Hospitals, University ; Humans ; Inpatients ; Pilot Projects

Purpose: The purpose of this study was to examine the effects of a mobile application on quality of life, wellness, and preventive behaviors against dementia among older adults who use senior citizen centers. Methods: Seventy-two older adults who used senior citizen centers were allocated to an intervention group (n=36) and a control group (n=36). The experimental treatment involved a cognitive enhancement program for preventing dementia using a mobile application for 12 sessions over 6 weeks. Data were analyzed using the t-test, chi-square test, Fisher’s exact test, paired t-test, and independent t-test. Results: The cognitive enhancement program based on a mobile application was effective for wellness (t = -3.87, p < .001) and preventive behaviors against dementia (t = -3.98, p < .001) for older adults who used a senior center. Conclusion The mobile application-based cognitive enhancement program developed in this study is recommended as an effective intervention for dementia prevention in older adults.

Aplasia cutis congenita is a congenital localized or widespread absence of the skin. We report a case of aplasia cutis congenita, type V, in a 6-day-old male infant born with the stellate and linear skin lesions covered by granulation tissue and soft capsule with slightly elevated erythematous edges on the trunk and lower extremities without any associated family history. The patient had amniotic bands and were diagnosed as aplasia cutis, type V. The patient received conservative treatment such as antiseptic dressing and prophylactic systemic antibiotics with healing of the ulcer.
Amniotic Band Syndrome ; Anti-Bacterial Agents ; Bandages ; Ectodermal Dysplasia* ; Granulation Tissue ; Humans ; Infant ; Infant, Newborn ; Lower Extremity ; Male ; Skin ; Ulcer