1.Induction of the c-fos in Rat Brain after Acute Carbon Monoxide Exposure.
Soo Hoon CHO ; Heon KIM ; Ho Jang KWON ; Mi Na HA
Korean Journal of Occupational and Environmental Medicine 1997;9(3):459-468
No abstract available.
Animals
;
Brain*
;
Carbon Monoxide*
;
Carbon*
;
Rats*
2.Change of Serum Electrolyte Level Following Succinycholine Administration.
Mi Na KWON ; Duck Mi YOON ; Yong Taek NAM ; Chung Hyun CHO
Korean Journal of Anesthesiology 1988;21(6):938-941
Succinylcholine(SCC) is well known to elevate the serum potassium level and to threaten life in some cases. In order to minimize the elevation of serum potassium following SCC, several attempts have been made such as SCC tamming and pretreatment with pancuronium or lidocaine or diazepam. Our study was undertaken to evaluate the change of serum potassium following induction in 60 patients divided into 7 different groups; group l. SCC 1mg/kg; group ll. SCC 2 mg/kg, grouplll, SCC 1mg/kg after SCC 10mg; group IV, SCC 1mg/kg after pancuronium 0.015mg/kg, group V. Pnacuronium 0.1mg/kg; group VI, SCC 1mg/kg after Lidocaine 1mg/kg; grou VII, SCC 1mg/kg after Diazepam 0.2mg/kg. The results were as follows: 1) Serum potassium were increased 0.14mEq/L in group l and 0.17 mEq/L in group ll. 2) Serum potassium were decreased in group lll, VI and VII than their control values but they were not statistically significant. 3) The decrease in serum potassium was most significant in group IV and V.
Calcium
;
Diazepam
;
Humans
;
Lidocaine
;
Pancuronium
;
Potassium
;
Succinylcholine
3.Induction versus expectant management in premature rupture of membranes at 34 to 37 weeks' gestation.
Joo Taek KWON ; Ho Myung HWANG ; Jong Hyun KIM ; Mi Ok NA ; Chul EUM ; Young Joo JUNG ; Sung Nam JO
Korean Journal of Obstetrics and Gynecology 2000;43(12):2135-2139
No abstract available.
Membranes*
;
Pregnancy*
;
Rupture*
4.Effects of Weight Control Program on Body Weight and the Sense of Efficacy for Control of Dietary Behavior of Psychiatric Inpatients.
Mi Na HONG ; Geum Sun BAEK ; Yong Hee HAN ; Myung Soon KWON
Journal of Korean Academy of Nursing 2008;38(4):533-540
PURPOSE: This study was designed to examine the effects of a weight control program on body weight and the sense of efficacy for control of dietary behavior in psychiatric inpatients. METHODS: A quasi-experimental design was used. Data were collected from March 1 to September 30, 2007. Female mentally ill patients in closing psychiatry ward of H University Hospital participated in the study (16 persons in the experimental group and 13 in the control group). RESULTS: The weight control program including diet therapy, exercise, education and behavior modification therapy decreased the rate of weight gain in female mentally ill patients taking atypical antipsychotics, and effectively increased a sense of efficacy for control of dietary behavior. CONCLUSION: Weight control program had a positive effect as a nursing intervention to decrease obesity and to increase the sense of efficacy for control of dietary behavior of psychiatric inpatients in psychiatric inpatients.
Adult
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Cognitive Therapy
;
Diet Therapy
;
Exercise
;
Female
;
Health Behavior
;
Hospitals, Psychiatric
;
Humans
;
Inpatients/psychology
;
Mentally Ill Persons/*psychology
;
Middle Aged
;
Patient Education as Topic
;
Psychiatric Nursing
;
*Weight Loss
5.A Case of Mixed Germ Cell Tumor of Ovary: Complete Remission after Conservative Surgery and Bleomycin, Etoposide, Cisplatin (BEP) therapy.
Moon Ki KWON ; Poong Do HAM ; Min Jung KWON ; Mi Kyung JEE ; Wook Yull NA
Korean Journal of Obstetrics and Gynecology 2002;45(6):1069-1073
Malignant germ cell tumor of ovary is very rare and one of the most malignant gynecologic neoplasms usually affecting younger women. we experienced a case of 19-year old female with mixed germ cell tumor of ovary which was composed of endodermal sinus tumor and dysgerminoma. we report this case with a brief review of the literature.
Bleomycin*
;
Cisplatin*
;
Dysgerminoma
;
Endodermal Sinus Tumor
;
Etoposide*
;
Female
;
Genital Neoplasms, Female
;
Germ Cells*
;
Humans
;
Neoplasms, Germ Cell and Embryonal*
;
Ovary*
;
Young Adult
6.A Case of Pneumatosis Intestinalis Induced by Chemotherapy in a Patient with Lung Cancer.
Mi Hye KWON ; Sun Jung KWON ; Eugene CHOI ; Moon Jun NA ; Ji Woong SON
Journal of Lung Cancer 2008;7(2):101-102
Pneumatosis intestinalis is an uncommon condition that is characterized by the presence of gas within the bowel wall. We experienced a case of pneumatosis intestinalis after cession of chemotherapy and we herein report on this case. A 58-year old man was admitted to our hospital for the evaluation of incidentally recognized pneumatosis intestinalis. He was diagnosed as having non small cell lung cancer in August 2006 and he received radiation therapy for concomitant brain metastasis and SVC syndrome in September 2006. He achieved a partial response after completing 6 cycles of chemotherapy with gemcitabine and cisplatin. Newly enlarged lymph nodes were observed on the follow-up CT, and chemotherapy with paclitaxel and carboplatin was started in July 2007. Due to the lack of a response, the therapeutic regimen was switched to oral erlotinib. After 1 month of treatment, the follow-up CT for response evaluation revealed pneumatosis intestinalis in the ascending colon without any subjective symptoms such as fever or abdominal pain. The laboratory results were within the normal range except for a slight increase of leukocytes. He underwent right hemicolectomy, but he didn't survive his postoperative acute renal failure and pneumonia
Abdominal Pain
;
Acute Kidney Injury
;
Brain
;
Carboplatin
;
Cisplatin
;
Colon, Ascending
;
Deoxycytidine
;
Fever
;
Follow-Up Studies
;
Humans
;
Leukocytes
;
Lung
;
Lung Neoplasms
;
Lymph Nodes
;
Neoplasm Metastasis
;
Paclitaxel
;
Pneumonia
;
Quinazolines
;
Reference Values
;
Small Cell Lung Carcinoma
;
Erlotinib Hydrochloride
7.A Case Of Squamous Cell Carcinoma Arising In Mature Cystic Teratoma Of Left Ovary.
Poong Do HAM ; Moon Ki KWON ; Min Jung KWON ; Seung Yeop BAEK ; Mi Kyung JEE ; Wook Yull NA
Korean Journal of Obstetrics and Gynecology 2002;45(8):1439-1443
Mature cystic teratoma of the ovary is the most common ovarian germ cell neoplasm representing 10-20% of all ovarian tumors. Malignant transformation rarely takes place, which is approximately 1-2% of all cases. The most common malignancy arising in mature cystic teratoma is squamous cell carcinoma. The prognosis of malignant transformation developing in mature cystic teratoma is poor and the management is not established due to the rarity of malignant degeneration. A case of stage Ia squamous cell carcinoma which developed in mature cystic teratoma of left ovary in a 43-year-old female is presented. The ovarian tumor was woman's fist-sized with intact capsule. Left oophorocystectomy was done. Above case with a brief review of literature is given.
Adult
;
Carcinoma, Squamous Cell*
;
Female
;
Germ Cells
;
Humans
;
Ovary*
;
Prognosis
;
Teratoma*
8.A Case Of Intraperitoneal Hemorrhage Of Intraligamentary Pregnancy.
Moon Ki KWON ; Poong Do HAM ; Min Jung KWON ; Seung Yeop BAEK ; Mi Kyung JEE ; Wook Yull NA
Korean Journal of Obstetrics and Gynecology 2002;45(8):1427-1430
A case of intraperitoneal hemorrhage of intraligamentary pregnancy is one of the most unusual accidents in obstetrics and carries a high degree of maternal and fetal morbity and mortality. The diagnosis of intraligamentary pregnancy is rarely ever made prior to laparotomy. We report a case of it with a brief review of literatures concerned.
Diagnosis
;
Hemorrhage*
;
Laparotomy
;
Mortality
;
Obstetrics
;
Pregnancy*
9.Production of Monoclonal Anti-idiotypic Antibody to Monoclonal Anti-DNA Antibody.
Myung Hee KWON ; Jae Seung KANG ; Ho Joon SHIN ; Young Ju JANG ; Sun PARK ; Mi Lli Na LEE ; Hyung Il KIM
Korean Journal of Immunology 1998;20(2):109-117
It has been thought that autoimmune diseases like systemic lupus erythematosus and rhumatoid athritis are closely associated with anti-DNA antibodies (Abs). In studies of the control for anti-DNA Ab generation, an understanding of the regulatory mechanisms by anti-idiotypic Abs that influence the production of anti- DNA Abs would be facillitated by the availability of the hybridomas producing the pairs of DNA-specific and anti-DNA's idiotope-specific monoclonal antibodies (mAbs). We have produced a series of anti-DNA mAbs and then monoclonal anti-idiotypic Ab directed against idiotypic determinant of the 3D8 mAb that has the highest affinity to dsDNA and ssDNA among the anti-DNA mABs that we had obtained. The spleen cells of the MRL-Ipr/Ipr, autoimmune prone, mice were fused with P3X63Ag8.653 myeioma cells to obtain anti-DNA Ab secreting hybridomas. Out of the fourteen clones that showed strong binding to ssDNA, four clones had cross-reactivity with dsDNA whereas none of these clones reacted with left-handed z-DNA. The binding activities of the anti-DNA mAbs to various synthetic polynucleotide sequences were different respectively. Anti-idiotypic mAbs were generated by the fusion of myeloma cells and spleen cells from the Balb/c mice immunized with 3DB-Fab. We have produced two anti-idiotypic mAbs, B7 (IgG2a/k) and 02F3 (IgM/k), which were specific to 3DB-Fab and cloned the variable region of the heavy chain from the 02F3 hybridoma.
Mice
;
Animals
10.The Development of Systemic Health Management Program in the Small Scale Industry using Organic Solvents: Application of Neurobehavioral Core Test Battery(NCTB).
Soo Hun CHO ; Sang Hwan HAN ; Mi Na HA ; Dork Ro YUN ; Ho Jang KWON
Korean Journal of Occupational and Environmental Medicine 1995;7(2):258-268
It is known that there appear some nonspecific and delicate changes in neuropsychiatric aspect on the workers when they are exposed for a long period to low concentrated organic solvents in the work places. Therefore, it give rise to the necessity of developing a program for the health supervisor stationed in the work place to supervise these neurobehavioral health affection. In addition to the questionnaire posed to the workers exposed to organic solvents, the study team conducted NCTB(Neurobehavioral Core Test Battery) respectively on an exposed group and a non-exposed group to organic solvents. The study team compared the results and decided whether or not to apply the results to the evaluation program of health affection. The study team divided 132 workers in 6 car repairing factories and 2 textile printing factories into exposed group and non-exposed group, pairing them off into 66 research objects according to their age, sex, and job. Neurobehavioral test was conducted on 6 items, except the POMS test, of NCTB developed by the World Health 0rganization (WHO) . The study team conducted examinations of working environment on the exposed and non-exposed groups of each work place. The analysis of the collected materials for examinations were conducted with GC-MS. The concentration of the mix-ture in the air, relative to their respective threshold limit values (TLV) was calculated according to the formula of the ACGIH and the Korean threshold limits. The results indicated that for two of eight factories samples the recommended concentration limits for mixtures was exceeded. Of the six tests, the'digit span forward','digit span backward'and'digit symbol' produced conspicuous statistical differences between the two groups (p<0.1) as a result of compairing the test values by means of paired t-test. The results of respective analysis of the car repairing factories and textile printing factories revealed that the textile printing factories had greater differences between the exposed and the non-exposed than in the car repairing factories. It is presumably because the textile printing workers are continuously exposed to the organic solvents during working hours, whereas the car repairing workers are exposed only when they are doing painting works. The NCTB is assessed very useful in examining the neurobehavioral health affection under the exposure to organic solvents, and, therefore, the study team expects that the NCTB will play an important part in the course of developing a health program for the workers exposed to organic solvents.
Paint
;
Paintings
;
Questionnaires
;
Solvents*
;
Textiles
;
Threshold Limit Values
;
Workplace
;
World Health