1.Fecal Microbiota Transplantation against Gut Colonization Using a Multidrug-Resistant Organism
Seul Ki LEE ; Ji Eun CHOI ; Chae Min SHIN ; Mi-Na KIM
Annals of Clinical Microbiology 2021;24(3):97-104
Background:
Fecal microbiota transplantation against gut colonization using a multidrugresistant organism is a technique used to treat infections through normalizing the gut microbiota via fecal microbiota transplantation in patients with confirmed colonization by carbapenem-resistant Enterobacteriaceae (CRE) or vancomycin-resistant enterococci (VRE) based on a fecal culture test within the past one week. In this study, we aimed to determinethe safety and effectiveness of this technique.
Methods:
The safety and effectiveness were assessed via a systematic review. A literature search was conducted using five Korean databases, such as KoreaMed, and international databases, including Ovid-MEDLINE, Ovid-EMBASE, and Cochrane Library.
Results:
Main results are described here. From the studies retrieved using the aforementioned search strategy, the remaining 581 studies were screened using the inclusion and exclusion criteria, resulting in the selection of nine studies for further consideration. In terms of safety, many studies reported deaths and adverse reactions associated with different causes. Fewer studies reported the rate of colonization; however, the effect of colony rate was inconsistent when compared to no treatment group. Additionally, none of the studies assessed the recurrence rate, a decrease in the prevalence of diseases related to infection by multidrugresistant bacteria, and the quality of life.
Conclusion
Fecal bacterial colonization for the decolonization of intestinal multidrugresistant bacteria was evaluated using a technique that requires further research as there is insufficient literature evidence to validate its safety and efficacy in treating infections through normalizing the intestinal flora of patients with confirmed colonization by CRE or VRE.
2.Fecal Microbiota Transplantation against Gut Colonization Using a Multidrug-Resistant Organism
Seul Ki LEE ; Ji Eun CHOI ; Chae Min SHIN ; Mi-Na KIM
Annals of Clinical Microbiology 2021;24(3):97-104
Background:
Fecal microbiota transplantation against gut colonization using a multidrugresistant organism is a technique used to treat infections through normalizing the gut microbiota via fecal microbiota transplantation in patients with confirmed colonization by carbapenem-resistant Enterobacteriaceae (CRE) or vancomycin-resistant enterococci (VRE) based on a fecal culture test within the past one week. In this study, we aimed to determinethe safety and effectiveness of this technique.
Methods:
The safety and effectiveness were assessed via a systematic review. A literature search was conducted using five Korean databases, such as KoreaMed, and international databases, including Ovid-MEDLINE, Ovid-EMBASE, and Cochrane Library.
Results:
Main results are described here. From the studies retrieved using the aforementioned search strategy, the remaining 581 studies were screened using the inclusion and exclusion criteria, resulting in the selection of nine studies for further consideration. In terms of safety, many studies reported deaths and adverse reactions associated with different causes. Fewer studies reported the rate of colonization; however, the effect of colony rate was inconsistent when compared to no treatment group. Additionally, none of the studies assessed the recurrence rate, a decrease in the prevalence of diseases related to infection by multidrugresistant bacteria, and the quality of life.
Conclusion
Fecal bacterial colonization for the decolonization of intestinal multidrugresistant bacteria was evaluated using a technique that requires further research as there is insufficient literature evidence to validate its safety and efficacy in treating infections through normalizing the intestinal flora of patients with confirmed colonization by CRE or VRE.
3.A Study on the Propensity of Koreans in Choosing Dementia Care Settings.
Mi Mi JEON ; You Joung KIM ; Bin Na KIM ; Hanna KIM ; Su Jeong SEONG ; Ki Woong KIM
Journal of Korean Geriatric Psychiatry 2016;20(1):9-15
OBJECTIVE: This study was to investigate the factors that influence the propensity of Koreans in choosing care settings of dementia patients. METHODS: This study analyzed the data from the '2014 Nationwide Survey on Dementia Awareness of Koreans' that was conducted by the National Institute of Dementia. Korean's perception of care burden for dementia was measured with grading on its types. Also its influences on preference for care between facilities and homes were evaluated using multivariate analysis with socio-demographic characteristics. RESULTS: In terms of preferred care settings, respondents preferred facilities over homes in case of themselves and their family, respectively 77.5% and 68.2%. The preference for facilities was significantly influenced by the respondents' age for both themselves and their family. Additionally, the perception of relatively higher emotional and physical burden compared to economic burden significantly influenced preference for facilities for their family. CONCLUSION: Improving public awareness and setting-up a practical social supporting system are needed to reduce emotional and physical burden as well as economic burden of dementia. Furthermore, building up an appropriate and safer communities for dementia patients and their caregivers is much demanded for reducing their burdens.
Caregivers
;
Surveys and Questionnaires
;
Dementia*
;
Humans
;
Multivariate Analysis
4.Effects of an Evidence-Based Practice (EBP) Education Program on EBP Practice Readiness and EBP Decision Making in Clinical Nurses.
Ae Ri Na NAM ; Eun Ho LEE ; Jeong Ok PARK ; Eun Jung KI ; Su Min NAM ; Mi Mi PARK
Journal of Korean Academy of Nursing Administration 2017;23(3):239-248
PURPOSE: Today's clinical nurses deal with complex problems that need accurate evidence for practice and decision making. In this study the effectiveness of an EBP education program was examined. METHODS: A pre-posttest design was used for this study and participants were 46 nurses working at a tertiary hospital located in Suwon, Korea. Date collection was done before and after the education program, from July 27 to October 2, 2015. Data were analyzed using paired t-test and ANCOVA with SPSS 21.0. RESULTS: There were significant differences in scores before and after the EBP education program for EBP readiness: belief (t=-5.65, p<.001), implementation(t=-2.89, p=.006), competence (t=-4.21, p<.001), and for evidence-based decision making (t=-16.25, p<.001) by the nurses. CONCLUSION: The findings indicate that the EBP education program has positive effects on EBP belief, implementation, competence and evidence-based decision making. In the future, it is necessary to reinforce the content of the program in the clinical workplace and to provide continuous education for clinical nurses.
Decision Making*
;
Education*
;
Evidence-Based Practice*
;
Gyeonggi-do
;
Korea
;
Mental Competency
;
Tertiary Care Centers
5.Difficulty in Facial Emotion Recognition in Children with ADHD.
Na Young AN ; Ju Young LEE ; Sun Mi CHO ; Young Ki CHUNG ; Yun Mi SHIN
Journal of the Korean Academy of Child and Adolescent Psychiatry 2013;24(2):83-89
OBJECTIVES: It is known that children with attention-deficit hyperactivity disorder (ADHD) experience significant difficulty in recognizing facial emotion, which involves processing of emotional facial expressions rather than speech, compared to children without ADHD. This objective of this study is to investigate the differences in facial emotion recognition between children with ADHD and normal children used as control. METHODS: The children for our study were recruited from the Suwon Project, a cohort comprising a non-random convenience sample of 117 nine-year-old ethnic Koreans. The parents of the study participants completed study questionnaires such as the Korean version of Child Behavior Checklist, ADHD Rating Scale, Kiddie-Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version. Facial Expression Recognition Test of the Emotion Recognition Test was used for the evaluation of facial emotion recognition and ADHD Rating Scale was used for the assessment of ADHD. RESULTS: ADHD children (N=10) were found to have impaired recognition when it comes to Emotional Differentiation and Contextual Understanding compared with normal controls (N=24). We found no statistically significant difference in the recognition of positive facial emotions (happy and surprise) and negative facial emotions (anger, sadness, disgust and fear) between the children with ADHD and normal children. CONCLUSION: The results of our study suggested that facial emotion recognition may be closely associated with ADHD, after controlling for covariates, although more research is needed.
Checklist
;
Child
;
Child Behavior
;
Cohort Studies
;
Facial Expression
;
Humans
;
Mood Disorders
;
Parents
;
Surveys and Questionnaires
6.Acute gastroenteritis caused by calicivirus in childhood.
Dong Soo KIM ; Young Mock LEE ; Mi Na KI ; Ki Soon KIM ; Doo Sung CHUN ; Young Wha KANG ; Young Mi JI ; Jae Deuk YUN
Korean Journal of Infectious Diseases 2000;32(2):123-128
BACKGROUND: Rotavirus is the most common agent of acute gastroenteritis in childhood worldwide. Besides rotavirus, calicivirus is well known another important cause of acute gastroenteritis in childhood. However, caliciviral acute gastroenteritis has not been studied well in Korea. Here we report clinical manifestations of caliciviral acute gastroenteritis confirmed by RT-PCR. METHODS: Eleven patients who were admitted to Severance Hospital, Yonsei University College of Medicine from April 1998 to April 1999, were involved in this study. RNA was isolated from the stool of the patients. RT-PCR was done. Electrophoresis with the PCR products was done. Viruses were identified by electron microscope. Medical records were reviewed retrospectively. RESULTS: Infections occurred below 7 years of age in almost all patients. No sex predominance was found. The clinical manifestations were those of acute gastroenteritis, such as diarrhea, vomiting, poor oral intake, fever, nausea, or abdominal pain. Symptoms were less severe compared to rotaviral infection. CONCLUSION: In case of viral gastroenteritis caused not by rotavirus, we should keep in mind that calicivirus is a possible cause.
Abdominal Pain
;
Diarrhea
;
Electrophoresis
;
Fever
;
Gastroenteritis*
;
Humans
;
Korea
;
Medical Records
;
Nausea
;
Polymerase Chain Reaction
;
Retrospective Studies
;
RNA
;
Rotavirus
;
Vomiting
7.A Case Of Squamous Cell Carcinoma Arising In Mature Cystic Teratoma Of Left Ovary.
Poong Do HAM ; Moon Ki KWON ; Min Jung KWON ; Seung Yeop BAEK ; Mi Kyung JEE ; Wook Yull NA
Korean Journal of Obstetrics and Gynecology 2002;45(8):1439-1443
Mature cystic teratoma of the ovary is the most common ovarian germ cell neoplasm representing 10-20% of all ovarian tumors. Malignant transformation rarely takes place, which is approximately 1-2% of all cases. The most common malignancy arising in mature cystic teratoma is squamous cell carcinoma. The prognosis of malignant transformation developing in mature cystic teratoma is poor and the management is not established due to the rarity of malignant degeneration. A case of stage Ia squamous cell carcinoma which developed in mature cystic teratoma of left ovary in a 43-year-old female is presented. The ovarian tumor was woman's fist-sized with intact capsule. Left oophorocystectomy was done. Above case with a brief review of literature is given.
Adult
;
Carcinoma, Squamous Cell*
;
Female
;
Germ Cells
;
Humans
;
Ovary*
;
Prognosis
;
Teratoma*
8.A Case Of Intraperitoneal Hemorrhage Of Intraligamentary Pregnancy.
Moon Ki KWON ; Poong Do HAM ; Min Jung KWON ; Seung Yeop BAEK ; Mi Kyung JEE ; Wook Yull NA
Korean Journal of Obstetrics and Gynecology 2002;45(8):1427-1430
A case of intraperitoneal hemorrhage of intraligamentary pregnancy is one of the most unusual accidents in obstetrics and carries a high degree of maternal and fetal morbity and mortality. The diagnosis of intraligamentary pregnancy is rarely ever made prior to laparotomy. We report a case of it with a brief review of literatures concerned.
Diagnosis
;
Hemorrhage*
;
Laparotomy
;
Mortality
;
Obstetrics
;
Pregnancy*
9.Iron Deficiency and Feeding Practices in Infants and Young Children.
Kue Sook KIM ; Mi Kyung KIM ; Young YOO ; Shin Na KIM ; Soon Ki KIM
Journal of the Korean Pediatric Society 1998;41(8):1060-1069
PURPOSE: Iron deficiency anemia is the most common nutrient deficient disorder in infants and young children. Iron deficiency at this age group can cause seroius effects on mental and psychomotor development. The object of this study is to determine the prevalence of iron deficiency and evaluate its relationship with diet during the weaning period. METHODS: We conducted blood tests on 247 healthy, 5-24 months olds, who visited DongBu Municipal Hospital and the local health center for immunizations. One hundred and fifty-two children also had serum iron, TIBC, transferrin-saturation and serum ferritin tested. Mothers of 129 children answered a questionnaire about feeding practices and their children were divided into 3 groups according to age; groupl (5-11 mon.), groupll (12-17 mon.), grouplll (18-24 mon.). RESULTS: Out of the total number of subjects 7.3% (n=18) was anemic (Hbg<11g/dl) and the highest 9.4% was in groupl (5-11 mon.). Among 152, 32.2% (n=49) were in an iron deficient state (ferritin<10ng/ml). In group lll, 57.5% (23/40) were iron deficient. Transferrin saturation<10% was 13.8% (21/152) and ferritin<10ng/ml and/or TS<10% was 37.5%. Analysis of questionnaires is as follows : Total daily caloric intake was 771.9 +/- 264.0 Cal on average. Average daily iron intake was 5.5 +/- 2.7 mg, about half the recommended dietary allowance of 10mg. CONCLUSION: The prevalence of iron deficiency was high (32.9%) in 5-24 months olds. Because iron deficiency without anemia was 27.0%, we recommend to add serum ferritin to routine Hb indices test for iron deficiency evaluation. As average iron intake in weaning period was much less than recommended, it seems appropriate to emphasize feeding iron rich weaning foods.
Anemia
;
Anemia, Iron-Deficiency
;
Child*
;
Diet
;
Energy Intake
;
Ferritins
;
Hematologic Tests
;
Hospitals, Municipal
;
Humans
;
Immunization
;
Infant*
;
Iron*
;
Mothers
;
Prevalence
;
Surveys and Questionnaires
;
Recommended Dietary Allowances
;
Transferrin
;
Weaning
10.Iron Deficiency and Feeding Practices in Infants and Young Children.
Kue Sook KIM ; Mi Kyung KIM ; Young YOO ; Shin Na KIM ; Soon Ki KIM
Journal of the Korean Pediatric Society 1998;41(8):1060-1069
PURPOSE: Iron deficiency anemia is the most common nutrient deficient disorder in infants and young children. Iron deficiency at this age group can cause seroius effects on mental and psychomotor development. The object of this study is to determine the prevalence of iron deficiency and evaluate its relationship with diet during the weaning period. METHODS: We conducted blood tests on 247 healthy, 5-24 months olds, who visited DongBu Municipal Hospital and the local health center for immunizations. One hundred and fifty-two children also had serum iron, TIBC, transferrin-saturation and serum ferritin tested. Mothers of 129 children answered a questionnaire about feeding practices and their children were divided into 3 groups according to age; groupl (5-11 mon.), groupll (12-17 mon.), grouplll (18-24 mon.). RESULTS: Out of the total number of subjects 7.3% (n=18) was anemic (Hbg<11g/dl) and the highest 9.4% was in groupl (5-11 mon.). Among 152, 32.2% (n=49) were in an iron deficient state (ferritin<10ng/ml). In group lll, 57.5% (23/40) were iron deficient. Transferrin saturation<10% was 13.8% (21/152) and ferritin<10ng/ml and/or TS<10% was 37.5%. Analysis of questionnaires is as follows : Total daily caloric intake was 771.9 +/- 264.0 Cal on average. Average daily iron intake was 5.5 +/- 2.7 mg, about half the recommended dietary allowance of 10mg. CONCLUSION: The prevalence of iron deficiency was high (32.9%) in 5-24 months olds. Because iron deficiency without anemia was 27.0%, we recommend to add serum ferritin to routine Hb indices test for iron deficiency evaluation. As average iron intake in weaning period was much less than recommended, it seems appropriate to emphasize feeding iron rich weaning foods.
Anemia
;
Anemia, Iron-Deficiency
;
Child*
;
Diet
;
Energy Intake
;
Ferritins
;
Hematologic Tests
;
Hospitals, Municipal
;
Humans
;
Immunization
;
Infant*
;
Iron*
;
Mothers
;
Prevalence
;
Surveys and Questionnaires
;
Recommended Dietary Allowances
;
Transferrin
;
Weaning