No abstract available.
Myasthenia Gravis* ; Pregnancy*

PURPOSE: This study was conducted to construct and test a structural model on family life satisfaction of aged individuals living at home. The conceptual model was based on Bandura's self-efficacy and social cognitive theories (1977; 1986) and Bowen's (1976) family systems theory. METHODS: From January 25 to March 5, 2016, 227 older adults living at home completed a structured questionnaire. Data were analyzed to calculate the direct and indirect effects of factors affecting family life satisfaction. SPSS WIN 20.0 and AMOS 20.0 were used. RESULTS: The hypothetical model was a good fit for the data. The model fit indices were χ2=78.05, χ2/df=1.35, RMSR=.02, GFI=.98, AGFI=.96, NFI=.94, CFI=.98, and RMSEA=. 05. Family life satisfaction was positively affected by perceived collective family efficacy, status of physical health, family communication, and family support. Depression resulted in a significant negative effect. Family differentiation had a significant indirect effect on family life satisfaction. The model explained 76% of variance in family life satisfaction. CONCLUSION: Perceived collective family efficacy, status of physical health, depression, family differentiation, family communication, and family support were significant factors explaining family life satisfaction among older adults staying at home. Further research should be conducted to seek intervention strategies to improve family life satisfaction among older adults living at home by focusing on the respective contributing factors.
Adult* ; Depression ; Family Health ; Humans ; Models, Structural ; Personal Satisfaction ; Systems Theory

The thioureylene drugs, propylthiouracil and methylmercaptoimidazol(MMI), exert their antithyroid effect primarily through inhibition of thyroid peroxidase-catalyzed iodination of thyroglobulin. Recently the interest about the effect to the thyroglobulin synthesis of these drugs have been increasing. So we studied the MMI effect to the thyroglobulin synthesis in cultured porcine thyroid cells. Porcine thyroid cells were isolated by sequential trypsinization in the presence of EGTA, seeded at high density(1X10^6 cells/cm^2) and cultured. One week later, MMI was added in different concentrations(0, 0.2, 1, 5mM) with TSH only or with 4H(b-TSH, Insulin, Transferrin, Hydrocortisone) or without hormone. Medias were collected after 24 hours and compared the amount of thyroglobulin secreted. And also pulse-labeling were performed with S^35 cysteine/methionine(1-2uCi/well) for 30, 60, 90min at the same conditions.There was no significant change in the amount of the secreted thyroglobulin by MMI, and there was no significant change in the pulse-labeled interacellular thyroglobulin by MMI. And also there was no significant change in the secretion of TSH-stimulated thyroglobulin by MMI. So we conclude that MMI has no effect on the thyroglobulin synthesis in cultured porcine thyroid cells and also MMI has no effect on the TSH-stimulated thyroglobulin synthesis in cultured porcine thyroid cell.
Antithyroid Agents ; Egtazic Acid ; Halogenation ; Insulin ; Methimazole ; Propylthiouracil ; Thyroglobulin ; Thyroid Gland ; Transferrin ; Trypsin

The amount of thyroglobulin synthesized from thyroid cells and stored in colloid space in very important in thyroid hormone synthesis. The thyroglobulin synthesis is mainly regulated by TSH secreted from the pituitary gland. But recently there were some reports about the possibility that iodine regulated the thyroid protein synthesis. So our studied were conducted to determined whether iodine could have inhibitory effect on thyroglobulin synthesis and methimazole could abolish the inhibitory effect of idoine.Porcine thyroid cells were isolated by sequential trypsinization in the presence of EGTA, seeded at high density(1X10^6 cells/cm^2) and cultured. One week later, Nal was added in different concentrations(10^-7, 10^-6, 10^-5, 10^-4M). 24hour medias were collected and checked the amount of thyroglobulin secreted. And also pulse-labeling were performed with[^35S] cysteine/methionine(1-2 uCi/well) for 1 hour at the same conditions. We used 3mM methimazole and 10^-4M NaI to observe the blocking effect of methimazol in iodine.The extracellular thyroglobulin secretion was significantly decreased by iodine in dose dependent manner(82.4%, 80.7%, 76.8% and 73.1% of control). And also intracellular thyroglobulin synthesis was significantly decreased by iodide in dose dependent manner(100.5%, 83.4%, 82.3% and 79.4% of control). The inhibitory effect of iodide was abolished by methimazole(74.7% to 101.3% of control). These data indicate that high iodide inhibit the thyroglobulin synthesis and secretion from the thyroid cells, and furthermore autoregulation by iodide may include thyroglobulin synthesis. And also this effect is dependent on the generation of an organic form of iodine because methimazole abolish the inhibitory effect of iodide.
Colloids ; Egtazic Acid ; Homeostasis ; Iodine ; Methimazole ; Pituitary Gland ; Thyroglobulin ; Thyroid Gland ; Trypsin

PURPOSE: This study was done to examine the importance of health promotion behavior for infants and toddlers as perceived by mothers of children in early childhood, and graduate students in nursing and to provide information for health promotion in early childhood. METHODS: This study was a cross-sectional survey research study. The participants were 91 mothers of children in early childhood, and 115 graduate students in nursing. RESULTS: The comparisons showed that graduate students in nursing reported higher perception of the importance health promotion behavior for infants and toddlers than did the mothers. In health promotion behavior, the highest score was in the category of safety. CONCLUSION: Providing information by nurses is necessary to promote health promotion behavior for mothers of children in early childhood. Therefore, it is important for healthcare professionals to develop effective programs for these mothers who want to promote good health promotion behavior in their children.
Child ; Cross-Sectional Studies ; Delivery of Health Care ; Health Behavior ; Health Promotion ; Humans ; Infant ; Mothers ; Child Health

Neurilemmoma is a relatively rare, which was first described by Stout in 1935. Neurilemmoma is a neoplasm arising from Schwann cells. It is usually solitary and may be benign or malignant, solid or cystic, encapsulated or diffuse. We report one case of retroperitoneal neurilemmoma with review of literature.
Neurilemmoma* ; Schwann Cells

No abstract available.
Child* ; Humans

No abstract available.
Thyroglobulin* ; Thyroid Gland*

No abstract available.
Bone Density* ; Gonads*

PURPOSE: The purposes of this study were to develop a postpartum nursing intervention program for immigrant women and evaluate the effects on postpartum depression, child rearing confidence, home environment, and infant temperament. METHODS: This research was a non-equivalent control group pre-test and post-test design. Participants were pregnant immigrant women from China, Vietnam, and the Philippines residing in Kyunggi province and Seoul. Twenty women were assigned to the intervention group, and 19 women to the control group. For the intervention group, the women were visited at home and provided emotional support and parenting education for three months. To analyze the intervention effects, repeated measure ANOVA and t-test were used. RESULTS: Child rearing confidence was higher in the experimental group than the control group at interaction effect of time and group, six weeks and three months postpartum. However, there were no significant effects for maternal depression, infant temperament, and husband support. Home Observation for Measurement of the Environment (HOME) score in the experimental group was higher than that of the control group at three month postpartum. CONCLUSION: Results indicate that the nursing intervention program had positive effects and can be used to further the health status of immigrant mothers and children.
Child ; Child Rearing ; China ; Depression ; Depression, Postpartum ; Education, Nonprofessional ; Emigrants and Immigrants* ; Emigration and Immigration ; Female ; Gyeonggi-do ; Humans ; Infant ; Mothers* ; Nursing* ; Philippines ; Postpartum Period* ; Seoul ; Spouses ; Temperament ; Vietnam