One of the important activities nursing is the alleviating of discomfort including pain as providing comfort to patient. Postoperativediscom has been underestimated because it is only a part of postoperative physiological process and disappear in time. The study was designed to investigate the effect of relaxation technique on postoperative discomfort of patients with lumbosacral back pain. A total of 40 patients were selected as a subject from August 12th to October 10th 1995 who had been hospitalized at NS and OS nursing units in K medical center. Of them twenty were in the experimental group and the remaining twenty were in the control group in convenience sampling. The tools for study were Relaxation technique, designed to use postoperative setting adequately by Park, and Postoperative Discomfort Scale. The data were analyzed by use of t-test an x2 test. The study was concluded as follows : The main hypothesis, that "the experimental group who used relaxation technique will express a lesser score of postoperative discomfort than the control group who did not use relaxation technique" is divided into seven sub-hypotheses. Hypothesis 1, that "the experimental group will express less postoperative pain than the control group"was supported(t=-7.52, p=0.000). Hypothesis 2, that "the experimental group will express less postoperative feeling of unpleasantness than the control group"was supported(t=-7.04, p=0.000). Hypothesis 3, that "the experimental group will express less postoperative immobilization discomfort than the control group"was supported(t=-6.66, p=0.000). Hypothesis 4, that "the experimental group will show fewer nonverbal expressions of postoperative distress than the control group"was supported(t=-3.75, p=0.01). Hypothesis 5, that "the experimental group will use analgesic medication less frequently than the control group" was supported(t=-4.15, p=0.000). Hypothesis 6, that "the experimental group will have less change in vital sings between the pre and postoperative periods than control group"was supported only for respiratory rate(t=-4.06, p=0.000). Hypothesis 7. that "the experimental group will express less postoperative voiding difficulty than the control group"was not supported(t=0.06, p=0.951). As a result, this study showed that relaxation technique has the effect to postoperative discomfort of the patients with lumbosacral back pain, so the researcher thought it is enable for nurses to help patients undergoing postoperative discomfort.
Back Pain* ; Humans ; Immobilization ; Nursing ; Pain, Postoperative ; Physiological Processes ; Postoperative Period ; Relaxation*

No abstract available.
Gentamicins* ; Humans ; Infant, Newborn*

No abstract available.
Carcinoma, Transitional Cell*

No abstract available.
Mucocutaneous Lymph Node Syndrome* ; Thrombocytopenia*

No abstract available.
Glomerulonephritis*

The purpose of study was to develop and validate Korean Sleep Scale A which can be easily administrated by nurse for a wide range of adult subjects. Dimensions of adult concept were derived by literature review. Previously developed sleep scales were also analyzed in order to develop scales items. The Korean sleep scale A was structured as a 15 item, 4 point like type scale. The Scale was tested an 298 female and male adult subjects after pilottest and content validation. The results showed reliability by internal consistency of Cronbach's alpha=75 Construct validity was tested by factor analysis and known group technique. Factor analysis showed 4 factor-sleep pattern, sleep evaluation, sleep result, and cause of sleep disturbance. Theses four factors explained 55.9% of total variance. Correlations between factors ranged from .15-.32. There was correlation among Korean Sleep Scale A score, Verran and Snyder-Halpern(VSH) Sleep Scale scale, and sleep satisfaction scale score, r= .71(p=.00), r=.51(p=.03), respectively. These study results partially support reliability, construct validity, and criterion related validity of Korean Sleep Scale A. Further validation study is required with other subjects and other settings.
Adult ; Female ; Humans ; Korea* ; Male ; Weights and Measures

No abstract available.
Chlamydial Pneumonia* ; Humans ; Infant*

OBJECTIVE: A number of studies to improve in vitro culture conditions have been tried over past ten years by using co-culture system with helper somatic cells. However, the mechanism of coculture is poorly understood. This study was designed to understand the mechanism for the mode of actual action of co-culture system of ICR strain's 1-cell embryos with human oviduct epithelial cells by examining the effect of conditioned medium and contactless coculture using a cell culture insert on the embryo development and by measuring the level of superoxide anion from conditioned medium after co-culture. METHODS: ICR strain's zygote embryos were cultured in medium alone (control), coculture, conditioned medium, or contactless coculture system for 6 days. Conditioned media (CM) were prepared as following 5 groups. All CM were collected after culturing oviduct cells for 2 days. CM-1 was stored at -20degrees C until use, and CM-2 was prepared just before use as a culture medium. CM-3 was cocultured with embryos and retrieved just before use. CM-4 and CM-5 were derives from the microfilteration of CM-2 and CM-3, respectively, using Microcon-10 (10 kDa molecular weight cut-off). The percentage of the embryos developed to hatched blastocyst stage and the level of superoxide anion in supernatant from medium alone culture (control), coculture, and contactless coculture were measured. RESULTS: The rates of embryo development to the hatched blastocyst stage were significantly higher in coculture (43%) than in control (0%) (p<0.05). The CM-1 group had no embryo development since 2-cell embryonic stage, whereas the CM-2, CM-3, CM-4 and CM-5 groups had the improved development to 4 or 8 cell embryo stage, but the similar rate of development to hatched blastocyst compared to control. The effect of coculture on embryo develpment was disappeared in the contactless coculture group. The level of superoxide anion was significantly reduced in coculture group compared to control. CONCLUSION: It is concluded that the present coculture system overcomes the 2-cell block in vitro and improves the embryo development. This beneficial effect may be due to the direct cell-cell contact between embryo and helper cells or the removal of deleterious components from medium rather than the embryotrophic factors.
Animals ; Blastocyst ; Cell Culture Techniques ; Coculture Techniques* ; Culture Media, Conditioned ; Embryonic Development ; Embryonic Structures ; Epithelial Cells ; Female ; Humans ; Molecular Weight ; Oviducts ; Pregnancy ; Superoxides ; T-Lymphocytes, Helper-Inducer ; Zygote

BACKGROUND: Adrenalectomy does impair the expression of hypothalamic NPY gene in the rat and replacement of glucocorticoid by intracerebroventricular(ICV) route resulted in a normalization of refeeding hyperphagia and weight gain in adrenalectomized(ADX), food-deprived rats. The purpose of this study was to assess the direct effect of CNS glucocorticoid on hypothalamic NPY gene expression which occurs following food deprivation in ADX rats. METHODS: Adult male Wistar rats were fitted with ICV cannulae and restricted the food intake for 14 days. Adrenalectomy and sham operation were done on the 10th day and single ICV corticosterone acetate(100ug/2uL) was given in one ADX group(ADX+CORT, n=9) and vehicle (2uL) was given in another ADX group(ADX+VEH, n=9) and sham rats(SHAM+VEH, n=7). After experiment, we measured NPY mRNA on arcuate nucleus by in situ hybridization. RESULTS: The rate of weight loss of ADX rats closely parallded that of sham-operated rats. Plasma glucose and insulin levels were not significantly different in three groups. Hybridization density on the ARC in ADX+VEH rats(0.42+/-0.02uCi/g: p<0.05) was significantly reduced compared to that in sham controls(0.68+/-0. 11uCi/g). ICV corticosterone injection increased the hybridization density in ADX+CORT rats(0.53+/-0.04uCi/g) compared to vehicle alone, although this did not reach that of controls. NPY gene expression was 40% in ADX+VEH rats and 62% in ADX+CORT rats compared to control rats. CONCLUSIONS: These results are consistent with the hypothesis that CNS glucocorticoid deficiency appears to be responsible for the impairment of refeeding hyperphagia in ADX rats and the effect of CNS glucocorticoid deficiency is a manifestation of impaired activation of hypothalamic NPY gene expression in the ARC.
Adrenalectomy ; Adult ; Animals ; Arcuate Nucleus ; Blood Glucose ; Catheters ; Corticosterone* ; Eating ; Food Deprivation ; Gene Expression ; Humans ; Hyperphagia ; In Situ Hybridization ; Insulin ; Male ; Rats* ; Rats, Wistar ; RNA, Messenger* ; Weight Gain ; Weight Loss

MRI (magnetic resonance imaging ) had been the most up-to-dated modality in evaluating white matter disease in recent years, whereas US (ultrasonogram) has been used extensively in diagnosis of neonatal PVL(periventricular leukomalacia) conventionally. We evaluated the diagnostic value of MRI by reviewing the MR findings and correlation of MR and US of PVL in II preterm infants. Evaluation criteria were MR signal intensity and discrimination of PVL on each pulse sequences land comparision between MR and US findings performed simultaneously, on the extent of PVL, size of the largest cyst and detectability of hemorrhagic lesion. MR findings of 11 cases of PVL were of low signal patterns on T1WI (T1weighted image) in 7, low signal patterns of PDWI (proton density weighted image) in 9, iso signal patterns on T2WI(T2weighted image) in 8 and low signal patterns on STIR(short time inversion recovery) in 7 cases. The lesions of 11 PVL were well discriminated in all 11 cases of T1WI, 7 cases of STR, 5 case of PDWE and 2 cases of T2WI. The lateral ventricle was diffuse dilated (n=1) and focally dilated (n=3) in atrial area. In the comparative study, MR presented more extensive lesions in 7 cases, larger cysts in 6 cases out of 7 PVL and more definitive hemorrhage in 3 cases out of 4 cases than sonography. In conclusion MR was more valuable than sonography in evaluating the extent of lesions, size of the largest cystic lesion and detetion of hemorrhage. TIWI and STIR images were more useful in detection of PVL than T2WI and PDWI.
Diagnosis ; Discrimination (Psychology) ; Hemorrhage ; Humans ; Infant, Newborn ; Infant, Premature ; Lateral Ventricles ; Leukoencephalopathies ; Magnetic Resonance Imaging