1.Evaluation of Enzyme Immunoassay for the Diagnosis of pulmonary Tuberculosis.
Jin Hee PARK ; Jung Won HUH ; Mi Ae LEE
Korean Journal of Clinical Microbiology 2000;3(1):48-52
BACKGROUND: The diagnosis of tuberculosis has been based on the detection of tubercle bacilli by acid-fast stain of smear or cultures, and recently the serologic diagnosis of tuberculosis has been provided a means of sensitive and specific detection of Mycobacterium tuberculosis. We evaluated the utility of enzyme immunoassay using determiner Tuberculosis Glicolipids(TBGL) antibody kit(Kyowa Medex Co. Ltd, Japan) to detect anti-TBGL antibody for diagnosis of pulmonary tuberculosis. METHODS: Anti-TBGL antibody assay was performed to the form 44 patients with active pulmonary tuberculosis(17 patients with smear positive, 7 patients with only culture positive, 20 patients with clinically active tuberculosis) and 80 controls (30 healthy controls, 24 patients with non-tuberculous respiratory diseases, 26 patients with inactive tuberculosis). We compared the sensitivity and specificity of anti-TBGL antibody with culture and AFB stain. RESULTS: Anti-TBGL antibodies were detected in 16 of 17(94%) smear positive patients, 4 of 7 patients with only culture positive and 16 of 20(80%) smear negative patients who had been clinically diagnosed as active pulmonary tuberculosis. Nine(35%) out of 26 patients with inactive tuberculosis, one(4%) out of 24 patients with non-tuberculous respiratory diseases and no one of healthy control had a positive antibody response. Overall sensitivity, specificity of the anti-TBGL antibody assay were 82%, 88%, respectively and sensitivities and specificities of culture and AFB smear 64%, 97%, and 49%, 100%, respectively. Anti-TBGL antibody titers in patients with active tuberculosis were significantly higher than control grup(P<0.05). Conclusions : The anti-TBGL antibody assay was sensitive, rapid and convenient. This assay will be useful as a tool for the diagnosis of tuberculosis in combination with other conventional methods.
Antibodies
;
Antibody Formation
;
Diagnosis*
;
Humans
;
Immunoenzyme Techniques*
;
Mycobacterium tuberculosis
;
Sensitivity and Specificity
;
Tuberculosis
;
Tuberculosis, Pulmonary*
2.Comparison of Fine Needle Aspiration Cytologic Diagnoses and Histologic Diagnoses in 256 Breast Lesions.
Mi Sun KANG ; Soo Jin JUNG ; Hye Kyoung YOON
Korean Journal of Cytopathology 1997;8(2):120-128
PURPOSE: Henoch-Schonlein purpura nephritis(HSPN) accompanied by nephrotic syndrome(NS) is known to have a poor prognosis and effective treatment is still controversial, even though both corticosteroids and immunosuppresant have been used for therapy. Cyclosporine A(CsA) is a well known immunosuppresant and widely used in renal transplantation and glomerular diseases especially steroid resistant. The aims of this study was to evaluate the therapeutic effect of CsA and to compare CsA with previously reported our data of rifampin(RFP) and azathioprine(AZA) in children with HSPN accompanied by NS. METHODS: 37 HSPN patients with NS confirmed by renal biopsy were selected. Of these, 17 patients were treated with CsA(5 mg/kg/day) for 6-8 months, 7 children were treated with RFP(10-20 mg/kg/day) for 9-12 months and 13 patients were treated with AZA(2 mg/kg/day) for 8 months. Along with these regimens, low dose oral prednisolone(0.5-1 mg/kg, qod) was also used. Sequential renal biopsy was done in all patients 1 month after termination of treatment. RESULTS: Complete remission rate of nephrotic syndrome was 5S.8% in CsA, 57.1% in RFP and 38.4% in AZA group after 17, 22, 11 months of mean follow-up period. Overall remission rate including partial remission was 88.2% in CsA, 85.7% in RFP and 84.6% in AZA group. Disappearance rate of hematuria was 58.8% in CsA, 57.1% in RFP and 46.2% in AZA group. Improvement of grade of clinical status was observed in 17 out of 17 CsA, 7 out of 7 RFP and 10 out of 13 AZA group. Improvement of pathologic class on sequencial renal biopsy was shown in 5 CsA(29.4%), none RFP(0%) and 2 AZA group(12.4%). Improvement on histologic immune-deposition was seen in 15 CsA(88.2%), 6 RFP(85.9%) and 4 AZA group(30.8%). CONCLUSION: In conclusion, Both CsA and RFP treated groups showed better result in complete remission rate of nephrotic syndrome and significant inprovement of histologic immune-deposition compared with AZA treated group(p=0.004). So, we recommend CsA and RFP rather than AZA for immunosuppresant treatment in HSPN with nephrotic syndrome.
Adrenal Cortex Hormones
;
Biopsy
;
Biopsy, Fine-Needle*
;
Breast*
;
Child
;
Cyclosporine
;
Diagnosis*
;
Follow-Up Studies
;
Hematuria
;
Humans
;
Kidney Failure, Chronic
;
Kidney Transplantation
;
Nephrotic Syndrome
;
Prognosis
;
Purpura, Schoenlein-Henoch
3.Psychosocial Adaptation in Children with Growth Hormone Deficiency.
Mi Jung PARK ; Yee Jin SHIN ; Hae Jung SHIN ; Duk Hee KIM
Journal of Korean Society of Pediatric Endocrinology 2000;5(1):83-92
PURPOSE: Emotional and behavioral disturbances have been reported in severe short stature children. The purpose of this study was to examine psychosocial problems in children with Growth hormone deficiency(GHD), comparing with their normal height siblings. METHODS: Twenty three children with GHD(17 boys and 6 girls, mean age:13.1+/-2.8 yrs) were included. Their normal height siblings(8 boys and 2 girls, mean age:12.3+/-2.9 yrs) were included as control group. Parents of all participating children completed the Child Behavior Checklist. Patients 10 years and older completed the Youth Self Report. RESULTS: 1)Internalizing problem scores(somatic complaints, anxiety, depression, social incompetence) were higher in GHD compared to control group(49.0+/-15.0 vs 43.2+/-6.2, P<0.05). Externalizing problem scores and social competences were not different between GHD and control group. 2) Total problem scores in GHD were not different by sex. 3)Total problem scores were not different between idiopathic GHD and organic GHD. 4)Attention problems(r=0.45, P<0.05), delinquent behavior(r=0.49, P=0.01) and aggressive behavior(r=0.51, P<0.01) increased by age. 5)Height SDS negatively correlated with social problem(r=-0.47, P<0.05) and delinquent behavior(r=-0.61, P<0.01). Height SDS also negatively correlated with somatic complaints(r=-0.75, P<0.01), anxiety and depression(r=-0.66, P=0.01). CONCLUSION: Internalized problems such as somatic complaints, anxiety and depression were higher in GHD than control group. Behavioral problem scores were increased by age and behavioral problem scores were correlated with height deficit. When we treat GHD children, appropriate medical and psychological counseling should be included.
Adolescent
;
Anxiety
;
Checklist
;
Child Behavior
;
Child*
;
Counseling
;
Depression
;
Female
;
Growth Hormone*
;
Humans
;
Parents
;
Self Report
;
Siblings
4.Effect of immune globulin on the prevention of coronary artery aneurysm in Kawasaki disease.
Mi Jin JUNG ; Chung Il NOH ; Jung Yun CHOI ; Yong Soo YUN
Journal of the Korean Pediatric Society 1991;34(5):668-676
No abstract available.
Aneurysm*
;
Coronary Vessels*
;
Mucocutaneous Lymph Node Syndrome*
5.Foreign Bodies in the Chest: How Come They Are Seen in Adults?.
Tae Jung KIM ; Jin Mo GOO ; Min Hoan MOON ; Jung Gi IM ; Mi Young KIM
Korean Journal of Radiology 2001;2(2):87-96
The radiologic and clinical findings of foreign bodies in the chest of children are well recognized. Foreign bodies in adults are infrequent, however, and the radiologic findings of these unusual circumstances have rarely been described. We classified various thoracic foreign bodies into three types according to their cause: Type I, Aspiration, Type II, Trauma or Accident; Type III, Iatrogenic. This pictorial essay will illustrate the radiologic findings and consequences of thoracic foreign bodies in adults, which have rarely been described in the radiologic literature. The clinical significance of thoracic foreign bodies will be also be discussed.
Accidents
;
Adolescent
;
Adult
;
Aged
;
Aspiration
;
Esophagus/radiography
;
Female
;
Foreign Bodies/*etiology/*radiography
;
Heart/radiography
;
Human
;
Iatrogenic Disease
;
Male
;
Middle Age
;
Radiography, Thoracic
;
Support, Non-U.S. Gov't
;
*Thorax
;
Wounds and Injuries/complications
;
Wounds, Gunshot/complications
6.Clinical Case Conference.
Jun Mi SONG ; Jung Jin KIM ; Jung Seo YI ; Kang Seob OH
Journal of Korean Neuropsychiatric Association 2010;49(4):353-360
No abstract available.
7.The comparison of coronary arterial dimensions measured by cross-sextional echocardiography with values obtained by coronary angiography in Kawasaki disease.
Mi Jin JUNG ; Jung Yun CHOI ; Chung Il NOH ; Yong Soo YUN ; I Seok KANG
Journal of the Korean Pediatric Society 1992;35(8):1102-1106
No abstract available.
Angiography
;
Coronary Angiography*
;
Coronary Vessels
;
Echocardiography*
;
Mucocutaneous Lymph Node Syndrome*
8.A Study on Laparoscopic Sacral Colpopexy for Uterine Prolapse.
Eun A CHO ; Mi Jung UM ; Suk Jin KIM ; Hyuk JUNG
Journal of Menopausal Medicine 2017;23(3):190-195
OBJECTIVES: We sought to describe the perioperative and postoperative adverse events associated with sacral colpopexy and evaluate the surgical outcome, complications, and benefits of laparoscopic sacral fixation for patients with pelvic prolapse. METHODS: Ninety-two women with uterine prolapse underwent sacral colpopexy between January 2011 and September 2016 at Chosun University Hospital. Patients' electronic medical records were investigated for demographic, intraoperative, and postoperative data. Strict definitions were used for all clinically relevant adverse events. Patients' outcomes were documented with 1 self-administered quality of life questionnaires: the Pelvic Floor Distress Inventory-20 focused on symptom distress. The primary analysis looking at perioperative and postoperative adverse events was descriptive and statistics were reported for all groups as n/N (%) with 95% confidence intervals for categorical variables and as mean ± standard deviation and mean (range) for all continuous variables. RESULTS: Their mean age was 69 ± 8.1 years, mean follow-up duration was 12 months, and mean operating time was 61 minutes. There were seven conversions due to anesthetic or surgical difficulties. Follow-up was performed using a telephone questionnaire and physical examination at 12 months. There were three cases of sacral pain with strong analgesics, one of vaginal erosion, two of transient urinary retentions, one of spondylitis, and two of mesh infection. Of the patients, 98.9% were satisfied with the surgical results, while none complained of sexual dysfunction or problems performing her usual activities. CONCLUSIONS: Laparoscopic sacral colpopexy is a feasible and highly effective technique that offers good long-term results with complication rates similar to those of open surgery with the added benefit of being minimally invasive.
Analgesics
;
Electronic Health Records
;
Female
;
Follow-Up Studies
;
Humans
;
Laparoscopy
;
Pelvic Floor
;
Physical Examination
;
Postoperative Complications
;
Prolapse
;
Quality of Life
;
Spondylitis
;
Telephone
;
Uterine Prolapse*
9.Pain and Pain Management in Hospitalized Cancer Patients.
Mi Jung KIM ; Jin A PARK ; Su Jin SHIN
Journal of Korean Academy of Fundamental Nursing 2008;15(2):161-170
PURPOSE: The purpose of this study was to provide basic data for proper pain management. METHOD: Data were collected from 85 hospitalized patients with cancer pain. A retrospective chart review of level of pain, source of pain, verbal expression of pain, and pain management was done. The data were analyzed with the SPSS program. RESULTS: The level of pain measured by NRS at the three time points was as follows: Time 1 (4.40+/-2.25), Time 2 (0.61+/-1.30), Time 3 (2.47+/-2.75). The kinds of pain were somatic pain (51.8%), visceral pain (37.6%), neuropathic pain (12.9%). The analgesic amount measured by OME (oral morphine equivalent) was as follows: Time 1 (70.85+/-69.65), Time 2 (91.61+/-89.20), Time 3 (96.71+/-94.25). Degree of pain had significant differences according to type of cancer (F=-3.286, p= .002), cancer origin (F=2.906, p= .018), and metastasis (F=2.906, p= .018) at Time 2. Best control period had significant difference according to type of cancer (F=2.373, p= .023), and origin of cancer (F=2.466, p= .040) at Time 2. CONCLUSION: These finding will enable the application of nursing interventions for pain control in cancer patients, identification of kinds of nursing compared to priorities, and increased levels of comfort in cancer patients in clinical settings.
Analgesics
;
Humans
;
Morphine
;
Neoplasm Metastasis
;
Neuralgia
;
Nociceptive Pain
;
Pain Management
;
Retrospective Studies
;
Visceral Pain
10.Acute renal failure with back pain after exercise.
Hae Jung PARK ; Mi Jung KIM ; Dong Kyu JIN ; Hae Il CHEONG ; Yong CHOI ; Kwang Wook KO ; Jung Mi PARK ; Kyung Mo YEUN
Journal of the Korean Pediatric Society 1991;34(6):863-868
No abstract available.
Acute Kidney Injury*
;
Back Pain*