1.Enhancement of Immunogenicity of the Inefficient Antigen Through DNA Vaccine-based Epitope Modification.
Soong Hwa JANG ; Mi Jin KIM ; Yong Suk JANG
Korean Journal of Immunology 2000;22(3):111-116
No abstract available.
DNA*
2.A Research on Analysis of Eating Habits and Textbook Contents for Efficient Nutrition Education of Elementary School Students in Gangneung City.
Journal of the Korean Dietetic Association 2007;13(4):379-388
This study empirically examined the actual level of elementary school children's knowledge of nutrition and the extent of current nutrition education for the children through the use of textbooks. Two or three classes were sampled from each of six schools, respectively, in Gangneung; of the 562 questionnaires that were distributed, 537 were returned and used for analysis. Respondents were all sixth-graders, on average boys and girls were 153.02+/-8.19cm and 152.79+/-7.15cm in height and 45.27+/-10.32kg and 43.33+/-7.46kg in weight, respectively, which was consistent with others' research. Most children had two siblings and a working mother, considered that they were well off, and their mother prepared meals. Children regularly had breakfast and dinner, although more children had dinner than breakfast. As a whole, their knowledge of the main nutrients contained in foods was lower than their general knowledge of nutrition. There were significant differences in knowledge of the main nutrients contained in foods, with girls showing more knowledge than boys (p<0.01). Most of them learned about nutrition at school, followed by home. At school, Practical Technology classes taught them the most about nutrition. Although Physical Education classes were expected to teach about nutrition in a quantitative way, they accounted for just 4.7% of the overall knowledge. As for the children's understanding of nutrition education through use of a textbook at school, just 19% of the students gained a very good understanding. As for interest in nutrition education at school, 22.2% of the students had no interest, while girls were more likely to have their interest in nutrition education at school affected by knowledge of nutrition than boys. For both boys and girls, the most desired method of education was cooking practice. More research across subjects is necessary so that nutrition education concentrated on the curriculum for fifth-graders can be provided by stages from the lower grades. Since cooking practice or games were preferred, it is necessary to develop nutrition education methods to incite active interest rather than passive education.
Breakfast
;
Child
;
Cooking
;
Curriculum
;
Surveys and Questionnaires
;
Eating*
;
Education*
;
Female
;
Gangwon-do*
;
Humans
;
Meals
;
Mothers
;
Physical Education and Training
;
Siblings
3.Effect of Intravenous Immunoglobulin(IVIG) on Renal Function in Very Low Birth Weight Infants.
Journal of the Korean Pediatric Society 1996;39(4):475-481
PURPOSE: This study was conducted to evaluate the effect of IVIG infusion on renal function in VLBW infants. IVIG has been proved quite safe in neonates given prophylactic and therapeutic doses. But nephrotoxicity is not recognized as adverse in IVIG therapy, only several previous adult cases have been noted. METHODS: For a total of ten VLBW infants who had not been received any medication except parenteral nutrition, vitamin and Fe supplements was assigned for study. To observe changes in renal function after preventive dose of IVIG administration(500mg/kg, 1dose) serum BUN and creatinine, 2-microglobulin( 2-MG) and N-acetyl- -D-glucosaminidase(NAG) were obtained prior to study and 1, 3 and 7 days after infusion. RESULTS: 1) There were no elevation of serum BUN and creatinine after IVIG administration, 2) There was transient increase of urine NAG from 1.1+/-0.7 u/mg creatinine before infusion to 2.7+/-5.3 u/mg creatinine on the first day of infusion, which was not statistically significat, decreasing to pretreatment level on the 3rd and 7th days after infusion. 3) There was transient increase of urine 2-MG from 294.6+/-223.8 microgram/mg creatinine before infusion to 680.0+/-108.9 microgram/mg creatinine on the first day and 416.0+/-246.3 microgram/mg creatinine on 3rd day after infusion, which was not statistically significant. CONCLUSIONS: It was found that prophylactic dose of IVIG in VLBW infants does not cause clinically significant impairment of renal function. but mild increment of urine NAG and 2-MG may suggest the possibility of renal tubular damage. Based on these results, further evaluation of the effect of IVIG on renal function in VLBW infant is recommended.
Acetylglucosaminidase
;
Adult
;
Creatinine
;
Humans
;
Immunoglobulins, Intravenous
;
Infant*
;
Infant, Newborn
;
Infant, Very Low Birth Weight*
;
Parenteral Nutrition
;
Vitamins
4.A Clinical Observation on 24 Hour Holter Monitoring: The Differences between Day and Night Time.
Mi Young JANG ; Jong Hwa KIM ; Jong Man KIM ; Hong Soon LEE ; Hak Choong LEE
Korean Circulation Journal 1984;14(1):125-133
A modern development of ambulatory ECG monitoring gave great advances in the diagnosis and evaluation of various cardiac conditions. Fifteen cases of ischemic heart disease, 11 cases of nonischemic heart disease, 5 cases of noncardiac disease and 9 cases of normal healthy subjects were studied from January 1980 to July 1981 in national Medical Center, with the following results: 1) The heart rate was decreased during night time, with less decreasing tendency in patients with ischemic heart disease. 2) Among 30 cases, including 12 patients with ischemic heart disease, who didn't show arrhythmia on routine 12 lead ECG, 12 cases, including 6 patients with ischemic heart disease, showed arrhythmia on Holter monitoring. 3) Among 5 cases with ischemic heart disease who showed premature ventricular contraction on day time monitoring, 2 cases didn't show premature ventricular contraction on nigh time monitoring. 4) The S-T segment and T wave were changed during night time in 2 cases with ischemic heart disease and in 2 normal subjects. From these results, we could assert that Holter monioring or ambulatory ECG tracing would be a good method for diagnosis and evaluation of ischemic heart disease, and other cardiac conditions. Several another studies with this equipment have to be performed and would give more distinctive outcomes.
Arrhythmias, Cardiac
;
Diagnosis
;
Electrocardiography
;
Electrocardiography, Ambulatory*
;
Heart Diseases
;
Heart Rate
;
Humans
;
Myocardial Ischemia
;
Ventricular Premature Complexes
5.Effect of malocclusion or orthodontic treatment on oral health-related quality of life in adults.
The Korean Journal of Orthodontics 2014;44(6):304-311
OBJECTIVE: The purpose of this study was to evaluate the effect of malocclusion or orthodontic treatment on oral health-related quality of life (OHRQoL) in adults. METHODS: The sample consisted of 860 adults (378 men and 482 women, aged 18-39 years) who were clinically evaluated for malocclusion or orthodontic treatment experience. Participants were divided into 4 groups as follows: normal occlusion, malocclusion, fixed treatment, and retention. OHRQoL was assessed with the short form of the Oral Health Impact Profile (OHIP-14) and Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ). RESULTS: The malocclusion group and the fixed treatment group had significantly higher OHIP-14 scores than the normal occlusion group and the retention group (p < 0.001). The malocclusion group had the highest PIDAQ score, while the normal occlusion group and the retention group had the lowest PIDAQ score (p < 0.001). Women had higher OHIP-14 and PIDAQ scores than men. A significant positive correlation was found between OHIP-14 and PIDAQ scores (p < 0.01). CONCLUSIONS: Malocclusion has a negative impact on OHRQoL, but this could be improved in adults through orthodontic treatment. These OHRQoL questionnaires can provide additional useful information on specific aspects of orthodontic patients' psychological state.
Adult*
;
Esthetics
;
Female
;
Humans
;
Male
;
Malocclusion*
;
Oral Health
;
Psychology
;
Quality of Life*
;
Surveys and Questionnaires
6.Risk Factors and Clinical Characteristics of Post-Renal Transplant Diabetes Mellitus.
Mi Hwa JANG ; Sun Dong JUNG ; Yong Hwan LEE ; Ji Hyun LEE ; Keun Tae KIM ; Jin Min KONG
Korean Journal of Nephrology 1998;17(6):957-963
To investigate the risk factors and clinical characteristics of postrenal transplant diabetes mellitus (PTDM), we reviewed the records of 177 renal allograft recipients in Maryknoll Hospiatal whose allografts had functioned longer than 6 months. Nineteen patients (10.7%) developed PTDM at 5.0+/-7.8 (1-52) months; 9 (47%) of these within 1 month. PTDM patients were older than nondiabetic renal transplants (42+/-2 vs 37+/-1 years, P<0.05). Body mass index tended to be higher in PTDM (23.5+/-1.0 vs 21.8+/-0.3kg/m2, P=0.09). Number of acute rejections (0.6+/-0.2 vs 0.5+/-0.1) and serum creatinine at 1 year after transplantation (1.2+/-0.8 vs 1.3+/-0.3mg/dL) were not different. Fasting (103.6+/-10.4 vs 84.4+/-1.6mg/dL, P<0.05) and postprandial (189.2+/-24.8 vs 118.6+/-2.3 mg/dL, P<0.01) blood sugars, measured before transplantation, were higher in PTDM. CsA blood level at 1 month posttransplantation was higher in PTDM (350+/-34 vs 279+/-8ng/mL, P<0.05). Fasting serum insulin was significantly higher (28.2+/-12.2 vs 7.3+/-2.0 microunit/dL, P<0.05) and serum C-peptide tended to be higher in PTDM patients compared with euglycemic renal recipients (6.3+/-1.6 vs 3.8+/-0.9ng/dL, P=0.08). All the PTDM patients were treated by either insulin or oral agent; 15 of 19 required no treatment after 4.7+/-6.9 months. In conclusion, prevalence of PTDM was 10.7%. PTDM patients were older. Body mass index was tended to be higher. Fasting and postprandial blood sugars, measured before transplantation, were higher in PTDM. Faslting serum insulin was higher and C-peptide tended to be higher in diabetics. These results suggested that increased insulin resistance plays a major role in the pathogenesis of PTDM.
Allografts
;
Blood Glucose
;
Body Mass Index
;
C-Peptide
;
Creatinine
;
Cyclosporine
;
Diabetes Mellitus*
;
Fasting
;
Humans
;
Insulin
;
Insulin Resistance
;
Prevalence
;
Risk Factors*
7.Infection Control Activity in Hallym University Medical Center.
Hyun Sook KOO ; Seung Ju KIM ; Hye Ryeung LEE ; Mi Hwa JANG ; Sung Soon HAN ; Heung Jeong WOO
Korean Journal of Nosocomial Infection Control 2001;6(2):117-124
No Abstract available.
Academic Medical Centers*
;
Infection Control*
8.Identification of p.Glu131Lys Mutation in the IHH Gene in a Korean Patient With Brachydactyly Type A1.
Mi Ae JANG ; Ok Hwa KIM ; Sun Wook KIM ; Chang Seok KI
Annals of Laboratory Medicine 2015;35(3):387-389
No abstract available.
Adult
;
Asian Continental Ancestry Group
;
Base Sequence
;
Brachydactyly/diagnosis/*genetics
;
DNA/chemistry/genetics/metabolism
;
DNA Mutational Analysis
;
Fingers/abnormalities
;
Hedgehog Proteins/*genetics
;
Humans
;
Male
;
Pedigree
;
Polymorphism, Single Nucleotide
;
Republic of Korea
;
Toes/abnormalities
9.Epidemiology and Clinical Characteristics of Rapid Response Team Activations.
Sei Won KIM ; Hwa Young LEE ; Mi Ra HAN ; Yong Suk LEE ; Eun Hyoung KANG ; Eun Ju JANG ; Keum Sook JEUN ; Seok Chan KIM
Korean Journal of Critical Care Medicine 2017;32(2):124-132
BACKGROUND: To ensure patient safety and improvements in the quality of hospital care, rapid response teams (RRTs) have been implemented in many countries, including Korea. The goal of an RRT is early identification and response to clinical deterioration in patients. However, there are differences in RRT systems among hospitals and limited data are available. METHODS: In Seoul St. Mary's Hospital, the St. Mary's Advanced Life Support Team was implemented in June 2013. We retrospectively reviewed the RRT activation records of 287 cases from June 2013 to December 2016. RESULTS: The median response time and median modified early warning score were 8.6 minutes (interquartile range, 5.6 to 11.6 minutes) and 5.0 points (interquartile range, 4.0 to 7.0 points), respectively. Residents (35.8%) and nurses (59.1%) were the main activators of the RRT. Interestingly, postoperative patients account for a large percentage of the RRT activation cases (69.3%). The survival rate was 83.6% and survival was mainly associated with malignancy, Acute Physiology and Chronic Health Evaluation-II score, and the time from admission to RRT activation. RRT activation with screening showed a better outcome compared to activation via a phone call in terms of the intensive care unit admission rate and length of hospital stay after RRT activation. CONCLUSIONS: Malignancy was the most important factor related to survival. In addition, RRT activation with patient screening showed a better outcome compared to activation via a phone call. Further studies are needed to determine the effective screening criteria and improve the quality of the RRT system.
Epidemiology*
;
Humans
;
Intensive Care Units
;
Korea
;
Length of Stay
;
Mass Screening
;
Patient Safety
;
Physiology
;
Reaction Time
;
Retrospective Studies
;
Seoul
;
Survival Rate
10.Effects of Brief Symptom Management Module on Inpatients with Chronic Schizophrenia: A Preliminary Study.
Choong Sik CHOI ; Jeong Ho CHAE ; Dong Won WOO ; Young Hee CHOI ; Woong HAHM ; Kyu Hang LEE ; Mi Hwa JANG
Journal of Korean Neuropsychiatric Association 2001;40(1):72-80
OBJECTIVES: The purpose of this study was to examine whether Symptom Management Module-Korean Brief Version(SMM-B) is effective as a psychosocial treatment of the inpatients with chronic schizophrenia. We also questioned which of demographic and clinical characteristics could be predictors of differential treatment response. METHODS: The subjects were composed of 30 inpatients with chronic schizophrenia, who were trained with weekly session of SMM-B for 5 weeks. Before and after the training, the level of psychopathology, knowledge about schizophrenia were assessed as dependent variables by using Clinical Global Impression(CGI) and Scale to Assess Unawareness of Mental Disorder(SUMD). RESULTS: Overall, patients showed improvement over the treatment period on psychopathology as well as knowledge about psychosis. Total scores of SUMD were changed from 16.9+/-4.0 before training to 12.9+/-4.2 after training(p<0.01) and scores of CGI were improved from 3.7+/-0.9 to 2.8+/-0.8 (p<0.01). However age, gender, years of education, age of onset, duration of illness, duration of admission, numbers of psychiatric admission, and clinical status evaluated by CGI were not correlated with un-awareness of psychosis. CONCLUSION: These results suggest that SMM-B could be a reliable method to improve self-awareness of psychosis in patients with chronic schizophrenia and one of important elements in rehabilitation.
Age of Onset
;
Education
;
Humans
;
Inpatients*
;
Psychopathology
;
Psychotic Disorders
;
Rehabilitation
;
Schizophrenia*