1.Multiple Granuloma Pyogenicum on Shoulder area.
Yoon Kee PARK ; Mi Jin Hee TAK
Korean Journal of Dermatology 1981;19(4):589-593
Granuloma pyogenicum is a benign vascular tumor, usually about 0.5 to 2cm in diameter. It occurs as a single lesion with few exceptions and consists of pedunulated nodule with a dull red or slightly purplish color. We observed a 29-year old man who had multiple satellite recurrences in the scapular region which developed after excision of a single lesion of granuloma pyogenicum. Histapathologic findings showed many newly formed capillaries that had prominant endothelial cells and showed varying degrees of dilation without appearance of epiderrnal collarette sign. The lesions were much improved by X-ray irradiation.
Adult
;
Capillaries
;
Endothelial Cells
;
Granuloma*
;
Granuloma, Pyogenic*
;
Humans
;
Recurrence
;
Shoulder*
2.Drug Eruption & Liver Damage due to Diaminodiphenyl - Sulfone (DDS): Report of a case.
Yoon Kee PARK ; Won Ho LEE ; Mi Ji Hee TAK
Korean Journal of Dermatology 1980;18(3):241-245
We report a case of drug eruption and liver damage due to diaminodiphenyl suIfone(DDS) ingestion in a 17-year-old female. This patient had taken DDS for 20 days, 100mg-200mg daily to treat an unknown skin disease. Thereafter, she had generalized erythematous eruption on whole body, icteric sclera and fever. Liver function test showed abnormality (SGOT 514 unit, SGPT 710 unit, alkarine phosphotase 4. 3 B.U., total biIirubin 7. Oml/dl, direct bilirubin 4. 8mg/dl). The adverse reactiions to DDS are gastrointestinal intolerance, hemolytic, anemia, methemoglobinemia, agranulocytoais, hepatitis, neuritis, psychosis and a skin rash described as a fixed drug eruption, erythema multiforme, exfoliative dermatitis and toxic epidermal necrolysis. In Korea, DDS has been used for the treatment of skin diseases of various types for a long time without prescription, especially in rural areas. This trend is a significant sociomediical problem in Korea.
Adolescent
;
Alanine Transaminase
;
Anemia
;
Bilirubin
;
Dermatitis, Exfoliative
;
Drug Eruptions*
;
Eating
;
Erythema Multiforme
;
Exanthema
;
Female
;
Fever
;
Hepatitis
;
Humans
;
Korea
;
Liver Function Tests
;
Liver*
;
Methemoglobinemia
;
Neuritis
;
Prescriptions
;
Psychotic Disorders
;
Sclera
;
Skin Diseases
;
Stevens-Johnson Syndrome
3.Expression and Antigenicity of Replicase Protein from Snow Mountain-like Caliciviruses,Korean Isolates.
Mi Yoon CHANG ; Jai Myung YANG ; Kyung Hee KIM
Journal of the Korean Society of Virology 1997;27(2):151-160
In view of the potential of replicase protein as a diagnostic reagent for human caliciviruses (HuCVs), we have cloned and over-expressed this gene from the Snow Mountain-like Korean strains in Escherichia coli as a fusion protein with glutathione S-transferase (GST, and described the preliminary antigenic characterization of the recombinant products. Each 470bp fragment corresponding to highly conserved region of RNA-dependent RNA polymerase was generated by RT-PCR from stools of two diarrheal children, cloned in pMOSBlue T-vector, and subcloned between the EcoRI and SalI restriction sites of pGEX-47-3, a GST gene fusion vector, yielding pGCVpol. This construct expressed a Snow Mountain-like HuCV replicate under the control of the IPTG-inducible pac promoter. An extract prepared by sonication of the E. coli cell inclusion bodies bearing pGCVpol products was purified and analyzed by SDS-PAGE. After Coomassie blue staining, it was shown that the recombinant replicase migrated on the gels with an approximate molecular mass of 46.5 kDa, that was subsequently cleaved into a 26 kDa GST fragment and a 20.5 kDa replicase protein upon digestion with thrombin protease. The replicase was recognized on immunoblotting with the sera from symptomatic children with the HuCV-associated diarrhea but not by asymptomatic sera from adults. The results presented the first biological activity of individually expressed HuCV replicase subunit and provided important reagents for diagnosis of HuCV infection.
Adult
;
Child
;
Clone Cells
;
Diagnosis
;
Diarrhea
;
Digestion
;
Electrophoresis, Polyacrylamide Gel
;
Escherichia coli
;
Gels
;
Gene Fusion
;
Glutathione Transferase
;
Humans
;
Immunoblotting
;
Inclusion Bodies
;
Indicators and Reagents
;
RNA Replicase
;
Snow*
;
Sonication
;
Staphylococcal Protein A
;
Thrombin
4.An Analysis of Articles for International Marriage Immigrant Women Related to Health.
Ok Hee AHN ; Mi Soon JEON ; Yoon Young HWANG ; Kyung Ae KIM ; Mi Sun YOUN
Journal of Agricultural Medicine & Community Health 2010;35(2):134-150
OBJECTIVES: This study was for analyzing the research about international marriage immigrant women and a trial to find the right direction for future research. METHODS: Sixty articles published from June, 2004 to June, 2009 were reviewed and analyzed according to the general characteristics, major of author, and theme of health domains. RESULTS: Most of them were master's thesis(71.7%) and journals(21.7%) and doctoral dissertation(6.7%) have been published mostly after thesis. Among 83.3% for quantitative research, descriptive(33.3%) and descriptive correlation(41.7%) methods were the most used and there were some qualitative researches(16.7%). The most frequently used data gathering method was questionnaire(81.7%) and the next was interview(16.7%). The major rates of the author were 61.7% for social welfare and 2.1% for nursing. The investigated variables in social health domain were adaptation(28.3%), and communication(1.7%). In psychological health domain, marriage satisfaction(16.7%), life satisfaction(11.7%), and depression(10.0%) were most researched. Utilization of medical center(5.0%) and health promotion behavior(1.7%) were investigated in physical health domain. CONCLUSIONS: Above this, most articles were researched about the adaptation of international marriage immigrant women. But the life in foreign countries can cause physical and psychosocial unhealthy conditions, so many-sided health related researches are supposed to be conducted for adaptation and prevention health problems of international marriage immigrant women.
Emigrants and Immigrants
;
Female
;
Health Promotion
;
Humans
;
Marriage
;
Social Welfare
5.The effects of passive smoking on children's respiratory illness.
Mi Jung LEE ; Soo Ann CHAE ; Kon Hee LEE ; Hae Sun YOON
Pediatric Allergy and Respiratory Disease 1993;3(1):14-22
No abstract available.
Tobacco Smoke Pollution*
6.Adenosis Tumor of the Breast: A Case Report.
Woo Hee JUNG ; Ki Keun OH ; Pyeong Ho YOON ; Mi Kyeong JUNG ; Jung Yeon SHIM
Journal of the Korean Radiological Society 1995;32(5):831-823
Adenosis tumor is a ra re tumor of the breast and primarily consists of adenosis. Authors report a case of surgically proved adenosis tumor in a 31-year-old woman. Mammogram showed a Iobulated, well-circumscribed mass with several surrounding radiolucent halos. In the center of the mass several linear radiolucent densities were seen with the appearance of a conglomerated well-circumscribed mass such as fibroadenoma. These linear radiolucent densities were consistent with the fat between the fibrous sclerosis in pathologic specimen. Ultrasonogram showed a well-circumscribed mass with homogeneous low echogenicity, partial posterior enhancement, and bilateral acoustic shadowings.
Acoustics
;
Adult
;
Breast*
;
Female
;
Fibroadenoma
;
Humans
;
Sclerosis
;
Shadowing (Histology)
;
Ultrasonography
7.Immunohistochemical Findings in 10 Cases of Inflammatory Myofibroblastic Tumor.
Soo Jin JUNG ; Mi Seon KANG ; Chang Hoon LEE ; Sook Hee HONG ; Hye Kyoung YOON
Korean Journal of Pathology 1999;33(9):717-722
A wide range of denomination has been used for inflammatory myofibroblastic tumor (IMT). IMT is not entirely homogeneous, even though it shows some overlapping histologic features such as haphazard proliferation of spindle cell and polymorphic chronic inflammatory cell infiltraion. The spindle cell is considered to be of myofibroblastic origin but follicular dendritic cell origin was reported recently. IMT is known as nonneoplastic, aberrant inflammatory response. However, IMT could show local invasion, recurrence, vascular invasion, and malignant transformation, and clonal characteristics and aneuploidy of IMT support the hypothesis that IMT may be a neoplastic process. In order to define the nature of spindle cell of IMT, immunohistochemical stains for smooth muscle actin (SMA), vimentin (VMT), lysozyme, S-100 protein, cytokeratin, CD21 were done. Additional immunohistochemical stains for MIB-1 for proliferating activity and LMP (latent membrane protein) for Epstein-Barr virus (EBV) were done. IMTs were composed of each 2 cases from lung, liver and lymph node and one case from common bile duct, maxillary sinus, bladder and thigh, and were histologically subclassified according to Coffin et al. Nine cases (90%) were positive for SMA and VMT, but no correlation between SMA and VMT immunoreactivity and histologic types was identified. Five cases (50%) were positive for lysozyme and S-100 protein, and histologic type III was negative for lysozyme and S-100 protein, and immunoreactivity for S-100 protein was different according to the histologic subtypes. All 11 cases were negative for CD21 and EBV LMP. MIB-1 labelling index was less than 1% in all cases. In summary, the spindle cell is regarded as myofibroblastic origin rather than follicular dendritic cell origin. Relationship with EBV is not clear, and negligible MIB-1 reaction suggests that IMT might have a good prognosis.
Actins
;
Aneuploidy
;
Coloring Agents
;
Common Bile Duct
;
Dendritic Cells, Follicular
;
Herpesvirus 4, Human
;
Immunohistochemistry
;
Keratins
;
Liver
;
Lung
;
Lymph Nodes
;
Maxillary Sinus
;
Membranes
;
Muramidase
;
Muscle, Smooth
;
Myofibroblasts*
;
Prognosis
;
Recurrence
;
S100 Proteins
;
Thigh
;
Urinary Bladder
;
Vimentin
8.Latent Mean Analysis of Health Behavior between Adolescents with a Health Problem and Those without: Using the 2009 Korean Youth Health Behavior Survey.
Jeong Mo PARK ; Mi Won KIM ; Yoon Hee CHO
Journal of Korean Academy of Community Health Nursing 2013;24(4):488-497
PURPOSE: The purpose of this study was to identify the construct equivalence of the general five factors of health behavior and to compare the latent means between adolescents with a health problem and those without in Korea. METHODS: The 2009 KYRBS (Korean Youth Risk Behavior Survey) data were used for the analysis. Multi-group confirmatory factor analysis was performed to test whether the scale had configural, metric, and scalar invariances across the existence of health problems in adolescents. RESULTS: Configural, metric, and factor invariances were satisfied for the latent mean analysis (LMA) between adolescents with health problem and those without. Adolescents with health problem and those without were not different in the LMA of all factors. CONCLUSION: Health providers should give more interest to the group of adolescents with health problems and consider prudential school life to the same group.
Adolescent*
;
Health Behavior*
;
Humans
;
Korea
;
Life Style
;
Risk-Taking
9.The Impact of Alcohol and Caffeine Intake on Body Mass Index, Alcohol Use Disorder, and Quality of Sleep among University Freshmen.
Journal of Korean Biological Nursing Science 2015;17(4):363-371
PURPOSE: The purpose of this study was to assess alcohol and caffeine intake and identify the impact of alcohol and caffeine intake on body mass index, alcohol use disorder, and quality of sleep among university students. METHODS: This study design was accomplished with a cross sectional survey and conducted from May to June 2014. One hundred and twenty-four freshmen of E university in S city, Korea were selected and evaluated by self-administered questionnaires. Alcohol and caffeine intake were measured by self-reported recall. The data were analyzed using descriptive analysis, independent t-test, one-way ANOVA, Pearson's correlation, and multiple linear regression. RESULTS: The average amount of alcohol intake was 175.02 +/- 219.97 g and the proportion of freshmen who took in more than 40g per day of alcohol was 75%. The average amount of caffeine intake was 116.79 +/- 111.14 mg. Factors influencing alcohol use disorder were dwelling type (t=2.25, p=.027) and alcohol intake (t=8.11, p<.001). And, the factor influencing quality of sleep was caffeine intake (t=3.88, p<.001). CONCLUSION: In order to reduce the harmful drinking of university students, preventive activities for freshmen are required and efforts on the part of the school needed.
Alcohol Drinking
;
Body Mass Index*
;
Caffeine*
;
Cross-Sectional Studies
;
Drinking
;
Humans
;
Korea
;
Linear Models
10.Maximal Diagnostic Accuracy in Virtual Telepathology System according to Input Device and Video Signal.
Rae Woong PARK ; Hee Jae JOO ; Hyunee YIM ; Yoon Mi JIN ; Kyi Beom LEE
Korean Journal of Pathology 1999;33(12):1191-1198
Varieties of telepathology system had been developed and in use, but their functional capability and diagnostic accuracy are considered to be inferior to those of conventional optical microscope. This study is intended to find out: 1) the diagnostic accuracy and reproducibility rate according to the input devices and the video signals; 2) any potential technical problems of the telepathology system; 3) any possible physical and psychological impacts. We devised a virtual telepathology system using our existing microscope equipped with CCD camera unit that has no restriction of network speed. Total fifty-five surgical pathology cases from 11 different organs were selected. Three pathologists were involved in making diagnoses. The resulting diagnostic accuracies were: 1 CCD camera with composite video signal was 86.2%; 3 CCD camera with composite video signal was 93.1%; 3 CCD camera with component video signal was 95.0%. The 3 CCD camera with component video signal resulted in 95.0% diagnostic accuracy and was superior to 1 CCD camera with composite video signal. Some technical problems noted during this study were: the visual field of the virtual telepathology system was smaller by 43% than that of microscope; the difference of cell sizes between microscope and monitor; low resolution of image. Some physical and psychological symptoms were noted.
Cell Size
;
Diagnosis
;
Pathology, Surgical
;
Telepathology*
;
Visual Fields