1.Leisure time physical activity and its relationship to coronary risk factors in male workers.
Yun Kyeong RHO ; Mi Hae YEH ; Sung Kook LEE ; Byung Yeol CHUN
Korean Journal of Preventive Medicine 1993;26(3):332-346
This study was attempted to observe leisure time physical activity pattern and its relationship to coronary risk factors(BMI, systolic blood pressure, diastolic blood pressure, serum total cholesterol, triglycerides, fasting blood sugar). Subjects participated in this study were 277 adult male workers of an industry in Kyungpook province, Korea. Energy expenditure were measured using modified Physical Activity History questionnaire of CARDIA study by interviewing. Serum total cholesterol, triglycerides and blood sugar level were tested with 5 ml fasting blood and height, weight and blood pressure were measured. Data on smoking and drinking habits and others were obtained. Geometric mean of leisure time physical energy expenditure were estimated as 212.80 kcal per week for study subjects and only 22.4% of them expended 2,000 kcal or more per week in leisure time physical activity. Taking walks or hikes and jogging or running were more frequent leisure time physical activities in study subjects. Statistically significant mean differences in total weekly leisure time physical activity for all coronary risk factors were not found among three groups. Because energy expenditure of leisure time was generally low in this subjects and most of them were healthy men, we did not found that leisure time physical activity was significantly associated with coronary risk factors.
Adult
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Blood Glucose
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Blood Pressure
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Cardia
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Cholesterol
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Drinking
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Energy Metabolism
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Fasting
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Gyeongsangbuk-do
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Humans
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Jogging
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Korea
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Leisure Activities*
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Male*
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Motor Activity*
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Surveys and Questionnaires
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Risk Factors*
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Running
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Smoke
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Smoking
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Triglycerides
2.Endothelial Dysfunction and Microvascular Complications in Type 1 Diabetes Mellitus.
Seon Mi JIN ; Chung Il NOH ; Sei Won YANG ; Eun Jung BAE ; Choong Ho SHIN ; Hae Rim CHUNG ; You Yeh KIM ; Yong Soo YUN
Journal of Korean Medical Science 2008;23(1):77-82
We examined whether alterations in vascular endothelial function and early structural changes in atherosclerosis are associated with microvascular complications in patients with type 1 diabetes mellitus (DM). Flow-mediated dilation (FMD) of the brachial artery and carotid intima-media thickness (IMT) measurement were performed in 70 young adults (aged 19 to 35 yr), 48 with type 1 DM, and 22 normal controls. Patients with diabetes had a lower peak FMD response (7.8+/-3.9 vs. 11.1 +/-1.9%, p<0.001) and increased IMT (0.51+/-0.10 vs. 0.42+/-0.07 mm, p<0.001) compared with controls. Twenty (41.7%) of the patients had microvascular complications including neuropathy, nephropathy, or retinopathy. In these complicated diabetic patients, we found a lower FMD response (6.1+/-2.5 vs. 9.9+/-3.5%, p=0.001) compared with diabetics without microvascular complications. The presence of microvascular complications was also associated with older age and longer duration of the disease. However, no differences were observed in IMT, body size, blood pressure, HbA1c, C-reactive protein, low-density lipoprotein or high-density lipoprotein cholesterol levels between complicated and non-complicated patients. Endothelial dysfunction and early structural atherosclerotic changes are common manifestations in type 1 DM, and endothelial dysfunction is thought to be an early event in the atherosclerotic process and important in the pathogenesis of microvascular complications.
Adult
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Diabetes Mellitus, Type 1/*complications
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Diabetic Angiopathies/*etiology
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Endothelium, Vascular/*physiology
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Female
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Humans
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Male
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*Microcirculation
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Tunica Intima/pathology
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Tunica Media/pathology
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Vasodilation