1.Relationship among Powerlessness. Self-Efficacy and Quality of Life in Hemodialysis Patients.
Myung Hwa LEE ; Myung Sook SONG ; Gyung Mi WOO
Korean Journal of Rehabilitation Nursing 2002;5(2):166-179
The purpose of this study was to the relationship between powerlessness, self-efficacy and quality of life in hemodialysis patients. The subjects were compromised of 198 hemodialysis patients from Pusan, Kyung-Sang Namdo and Kyung-Sang Bukdo 6 hemodialysis clinics. There were significant positive correlation between self-efficacy and quality of life(r= .512, p .00l). Data were collected by questionnaires from Sep. 19 to Oct. 27, 2001. The instrument used for study were the Powerlessness Behavioral Assessment Tool (Miller, 1983) and self-efficacy developed by Kim, Ju-Hyun(1995) and quality of life developed by Kim, Ok-Soo(1993). Collected data were analyzed by frequency, percentage, mean, standard deviation, t-test, ANOVA, Scheffe test, pearson correlation The results were as follows. 1. The mean score of powerlessness was 52.41+/-.93, mean mark 3.28+/-.43, and the mea score of self-efficacy was 45.44+/-.75, mean mark 2.87+/-.49, and the mea score of quality of life was 121.27+/-3.81. mean mark 2.96+/-.58. 2. There were significant differences in the level of powerlessness according to sex (1,=2.148, p= .033), occupation(t=3.682, p=.000), economic status(F=3.094, p=.048), experience of hospitalization (1,=-2.002. p= .047). 3. There were significant differences in the level of self-efficacy according to age(F=3.271. p=.013), economic status (F=5.759, p=.004), religion(F=2.667, p= .048), hemodialysis period(F=2.991. p =.032), hemodialysis frequency(t = 9.045, p = .003), experience of hospitalization (1,=4.40, p=.037). 4. There were significant differences in the level of quality of life according to occupation(t=3.796, p=.053), economic status(F=11.478, p=.000), hemodialysis frequency(t=7.573, p=.006). 5 There were significant negative correlation between powerlessness and self-efficacy (r=- .401. p .001), powerlessness and quality of .life(r=- .562, p .001),
Busan
;
Hospitalization
;
Humans
;
Quality of Life*
;
Surveys and Questionnaires
;
Renal Dialysis*
2.The effect of ultrasonic nebulized salbutamol in the first attacked wheezy infants.
Soo Young KWEON ; Young Mi HONG ; Gyung Hee KIM ; Seung Joo LEE ; Keun LEE
Journal of the Korean Pediatric Society 1991;34(11):1505-1511
No abstract available.
Albuterol*
;
Humans
;
Infant*
;
Ultrasonics*
3.A Forensic Psychiatric Study for Substance-Related Offenders.
Gyung Sook LEE ; Hyuk LEE ; Mi Kyung LEE ; Sang Sub CHOI ; Jung Hwa LEE
Korean Journal of Legal Medicine 2001;25(2):6-11
OBJECT: This study examined the demographic characteristics, abused substance types, comorbid psychiatric diagnosis and associated crimes of substance-related offenders. METHOD: We surveyed 205 offenders of substance-related crime from court. RESULT: Substance-related offenders were all men and most of them were unemployed, living alone in the major city and mean age was 27.9+/-5.77years. 78.5% frequently abused inhalants like adhesives and 17.1% abused the methamphetamine. They violated the 1 or more times and the classification of crimes was violence, rape and rape-injury, larceny, arson. Substance-related offenders had comorbid psychiatric disorder ; 26 of them had personality disorder, 23 had mood disorder and 13 had psychotic disorder. Mean hospital day was 14.8+/-6.55 months. CONCLUSION: Substance-related offenders were young single men without a job living major city. They had comorbid psychiatric disorder and high risk to commit crime.
Adhesives
;
Classification
;
Crime
;
Criminals*
;
Firesetting Behavior
;
Humans
;
Male
;
Mental Disorders
;
Methamphetamine
;
Mood Disorders
;
Personality Disorders
;
Psychotic Disorders
;
Rape
;
Violence
4.Implication for early implantation failure in women with hydrosalpinx : Hydrosalpingeal fluid inhibits trophoblast cell proliferation in vitro culture system.
Jee Ae LEE ; Bum Chae CHOI ; Hye Gyung BYUN ; Jung Wook KIM ; Jung Ryul HAN ; Geun Jae YOO ; Kye Hyun KIM ; Mi Gyung KOONG ; Joseph A HILL
Korean Journal of Obstetrics and Gynecology 2000;43(8):1344-1348
No abstract available.
Cell Proliferation*
;
Female
;
Humans
;
Trophoblasts*
5.Nutritional assessment to predict postoperative complications in patients with gynecologic surgery.
Gee Hyung KIM ; Young Tae KIM ; Eun Mi JO ; Eun Gyung CHOI ; Jae Wook KIM ; Sang Won PARK ; Gyung Joo LEE
Korean Journal of Obstetrics and Gynecology 2000;43(12):2185-2190
No abstract available.
Female
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Gynecologic Surgical Procedures*
;
Humans
;
Nutrition Assessment*
;
Postoperative Complications*
6.A case of Intramural Pregnancy following currettage , treated with Laparoscopic exicision and MTX .
Jae Yeon KIM ; Jae Joo LEE ; Jung Ho SONG ; Jae Gyung YOO ; Young Ryul CHOI ; Mi Sun LEE ; young Mi LEE ; In Soo HWANG
Korean Journal of Obstetrics and Gynecology 2000;43(11):2045-2049
Intramural pregnancy is one of the rarest form of ectopic pregnancy that only 20 cases have been reported in the world so far. Pathologically, the location of the gestational sac is completely isolated from the uterine cavity and entirely surrounded by myometrium without any contact of endometrium. Many reports noted that there would be possible relationship between the intramural pregnancy and prior uterine traumatic factor- curettage, cesarean section, myomectomy, salpingectomy, and manual removal of the placenta and so on. We have recently experienced a case of intramural pregnancy following curettage, managed completely by the laparoscopic excision and additive single dose intramuscular MTX treatment. So, we report this case with a brief review of the literature.
Animals
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Cesarean Section
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Curettage
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Endometrium
;
Female
;
Gestational Sac
;
Mice
;
Myometrium
;
Placenta
;
Pregnancy*
;
Pregnancy, Ectopic
;
Salpingectomy
7.Hepaplastin test for screen of vitamin K deficiency in term and preterm neonates.
Eun Mi KIM ; Gyung Og YU ; Dong Rak CHOI ; Chong Young PARK ; Hae Ran LEE ; Choon Myung RO
Journal of the Korean Pediatric Society 1992;35(5):614-620
No abstract available.
Humans
;
Infant, Newborn*
;
Vitamin K Deficiency*
;
Vitamin K*
;
Vitamins*
8.Efficacy and adverse events related to the initial dose of methimazole in children and adolescents with Graves’ disease
Hyun Gyung LEE ; Eun Mi YANG ; Chan Jong KIM
Annals of Pediatric Endocrinology & Metabolism 2021;26(3):199-204
Purpose:
The first-line antithyroid drug for children and adolescents with Graves’ disease (GD) is methimazole (MMI). This study evaluated the relationship between the initial MMI dose and the clinical course of GD after treatment.
Methods:
We studied the efficacy of the initial MMI dose and the relationship between the initial MMI dose and adverse events (AEs). We retrospectively enrolled 22 males and 77 females and divided those subjects into 3 groups according to the initial dose of MMI: <0.4 mg/kg/day (group A; n=32); 0.4–0.7 mg/kg/day (group B; n=39); and >0.7 mg/kg/day (group C; n=28).
Results:
The mean time to the normalization of free thyroxine (fT4) levels upon initial treatment was 5.64, 8.61, and 7.98 weeks in groups A, B, and C, respectively (P=0.116). The incidence of liver dysfunction, neutropenia, and skin rash was 12.5%, 20.5%, and 42.9% in groups A, B, and C, respectively (P=0.018). Neutropenia, as a severe AE, was absent in group A, but its prevalence was 7.7% in group B and 21.4% in group C (P=0.015). When comparing only groups B and C, the incidences of liver dysfunction and neutropenia were higher in group C (P=0.04 and P=0.021, respectively).
Conclusion
The mean time to the normalization of fT4 levels did not differ among the 3 groups, but the incidence of AEs was higher in the groups that received high MMI doses. High doses of MMI (>0.7 mg/kg/day) should be reconsidered as an initial treatment for children and adolescents with GD.
9.Efficacy and adverse events related to the initial dose of methimazole in children and adolescents with Graves’ disease
Hyun Gyung LEE ; Eun Mi YANG ; Chan Jong KIM
Annals of Pediatric Endocrinology & Metabolism 2021;26(3):199-204
Purpose:
The first-line antithyroid drug for children and adolescents with Graves’ disease (GD) is methimazole (MMI). This study evaluated the relationship between the initial MMI dose and the clinical course of GD after treatment.
Methods:
We studied the efficacy of the initial MMI dose and the relationship between the initial MMI dose and adverse events (AEs). We retrospectively enrolled 22 males and 77 females and divided those subjects into 3 groups according to the initial dose of MMI: <0.4 mg/kg/day (group A; n=32); 0.4–0.7 mg/kg/day (group B; n=39); and >0.7 mg/kg/day (group C; n=28).
Results:
The mean time to the normalization of free thyroxine (fT4) levels upon initial treatment was 5.64, 8.61, and 7.98 weeks in groups A, B, and C, respectively (P=0.116). The incidence of liver dysfunction, neutropenia, and skin rash was 12.5%, 20.5%, and 42.9% in groups A, B, and C, respectively (P=0.018). Neutropenia, as a severe AE, was absent in group A, but its prevalence was 7.7% in group B and 21.4% in group C (P=0.015). When comparing only groups B and C, the incidences of liver dysfunction and neutropenia were higher in group C (P=0.04 and P=0.021, respectively).
Conclusion
The mean time to the normalization of fT4 levels did not differ among the 3 groups, but the incidence of AEs was higher in the groups that received high MMI doses. High doses of MMI (>0.7 mg/kg/day) should be reconsidered as an initial treatment for children and adolescents with GD.
10.NCAM140 and pCREB Expression after Tianeptine Treatment of SH-SY5Y Cells.
Mi Gyung LEE ; Daeyoung OH ; Mi Ran CHOI ; Young Gyu CHAI ; Seok Hyeon KIM ; Dong Hoon OH ; Joonho CHOI
Psychiatry Investigation 2014;11(3):313-318
OBJECTIVE: Antidepressants Modulate Neuronal Plasticity. Tianeptine, An Atypical Antidepressant, Might Be Involved In The Restoration Of Neuronal Plasticity; It Primarily Enhances The Synaptic Reuptake Of Serotonin. Ncam140 Is Involved In Neuronal Development Processes, Synaptogenesis And Synaptic Plasticity. We Investigated The Effect Of Tianeptine On The Expression Of Ncam140 And Its Downstream Signaling Molecule In The Human Neuroblastoma Cell Line Sh-sy5y. METHODS: NCAM protein expression was measured in human neuroblastoma SH-SY5Y cells that were cultivated in serum-free media and treated with 0, 10, or 20 microM tianeptine for 6, 24, or 72 hours. NCAM140 expression in the tianeptine treatment group was confirmed by Western blot, and quantified through measurement of band intensity by absorbance. CREB and pCREB expression was identified after treatment with 20 microM tianeptine for 6, 24, and 72 hours by Western blot. RESULTS: Compared to cells treated for 6 hours, cells treated with 0 or 10 microM tianeptine for 72 hours showed a significant increase in NCAM140 expression and cells treated with 20 microM tianeptine showed a significant increase after 24 and 72 hours. The pCREB level in cells treated with 20 microM tianeptine increased in time-dependent manner. CONCLUSION: Our findings indicated that the tianeptine antidepressant effect may occur by induction of NCAM140 expression and CREB phosphorylation.
Antidepressive Agents
;
Blotting, Western
;
Cell Line
;
Culture Media, Serum-Free
;
Humans
;
Neural Cell Adhesion Molecules
;
Neuroblastoma
;
Neuronal Plasticity
;
Neurons
;
Phosphorylation
;
Plastics
;
Serotonin