1.A case report on SMART-EST action plan with lifestyle medicine approach in the non-pharmacologic management of the metabolic syndrome
Andres Kim L. Tan III, MD, DFM
The Filipino Family Physician 2023;61(1):36-40
Obesity and overweight are considered health risks for non-communicable diseases. Most clinical practice guidelines suggest lifestyle modification as the primary management and as an adjunct to pharmacologic treatment. Using the SMART-EST goaloriented action plan and lifestyle medicine may improve weight reduction outcomes.
The case presented had clinical criteria (3/5) for metabolic syndrome, diagnosed previously as obese stage II, asthma moderately uncontrolled, prediabetes, and mild dyslipidemia. Baseline weight and waist-to-hip ratio were taken and interpreted as obese stage II with a very severe risk for comorbidity.
The diagnostics used were fasting plasma glucose, lipid profile, HbA1c, and 2-D echocardiography on the eight months of intervention only.
Using the SMART-EST action plan plus Lifestyle medicine approaches as non-pharmacologic management for metabolic syndrome. There was an 11.4 % reduction in weight, improved fasting glucose, lipid profile, and 2-D echocardiography within the eight months of intervention.
Metabolic syndrome
2.The association between Betel Quid Chewing and Metabolic Syndrome among urban adults in Mandalay District of Myanmar
Aye Aye Aung ; Sai Ni Soe Zin ; Aung Ko Ko ; Aung Cho Thet
Journal of the ASEAN Federation of Endocrine Societies 2023;38(2):50-56
Background:
As the prevalence of metabolic syndrome, obesity and diabetes increase worldwide, the need to identify modifiable lifestyle risk factors also increases, especially those that may be relatively unique to a specific population. To explore a possible association between betel quid chewing and metabolic syndrome, a community-based cross-sectional study was conducted.
Methodology:
Three hundred ninety-one (391) adults were interviewed and the following parameters were measured: triglycerides, HDL-cholesterol, glucose, waist circumference, body mass index and blood pressure. Multiple logistic regression was used to determine the association between betel quid chewing and metabolic syndrome while controlling for confounders.
Results:
The prevalence of metabolic syndrome was similar in chewers and non-chewers, 50% and 49%, respectively. After controlling for other factors, development of metabolic syndrome was positively associated with number of betel quid chewed per day, age greater than 40 years , and a positive family history of hypertension and diabetes. Regarding the duration of betel chewing, when analyzed by sex, the risk was doubled in men compared to non-chewers (OR 2.15; 95% CI = 1.21, 3.84]). As a result, a man chewing more than 10 pieces (OR 2.49; 95% CI = 1.36, 4.57]) of betel quids per day for more than 10 years had a two-fold increased chance of developing the metabolic syndrome.
Conclusions
Frequency and duration of betel quid chewing may represent a behavioral lifestyle target for approaches to reduce the incidence of metabolic syndrome.
Metabolic Syndrome
3.Metabolic syndrome in hypertensive patients
Journal of Medical and Pharmaceutical Information 2003;0(11):36-39
With a control group of 43 health persons a study was performed on 131 hypertensive patients using the test of glucose tolerance. The average similar in 2 groups. In both 2 groups, an incidence of 36,78% of metabolic syndrome was concluded, among them 41,22% were in hypertensive group and 23,26% in control. The factors occurred with high frequency were diabetes, poor tolerance with glucose, BMI ≥ 23, high triglyceride levels ans low HDL- C levels subsequently
Syndrome
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Hypertension
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Metabolic Diseases
4.A patients with the X syndrome was diagnosed in the Department of Endocrine and Diabetes in Bach Mai Hospital
Pharmaceutical Journal 1999;370(8):29-31
Recent changes in lifestyle such as high-fat diet and inactivity have promoted a metabolic disorder titled syndrome X. At the moment, it is very rare in Vietnam but the prevalence of this syndrome is going to significantly increases in next decades. In Endocrinology and Diabetic Dept- Bach Mai Hospital, we found a 44 year-old patient, who met the basic criteria of the syndrome X: Hypertension, central obesity and high fasting serum Insulin. He has mild dyslipidemia. All members of his family, including his mother and his sister are also suffering from syndrome X with hypertension, obesity and overt diabetes mellitus. This patient was advised to have diet with caloric restriction and exercise to improve insulin resistance. He has been using gemfibrozil (Lopid) and metformin. After 2 months, he has lost 6 kilograms and felt better. His blood pressure was controlled without antihypertensive drugs
Metabolic Syndrome X
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diagnosis
5.Metabolic syndrome: cunent status and perspective.
Chinese Journal of Epidemiology 2006;27(12):1018-1019
6.Second thoughts on metabolic syndrome.
Chinese Journal of Epidemiology 2006;27(12):1017-1018
8.Hepokines in metabolic diseases.
Huixia ZHAN ; Xianglu RONG ; Jiao GUO
Chinese Journal of Hepatology 2015;23(5):397-400
9.Cardiometabolic risk factors leading to Diabetes Mellitus among the Young (YOD) from the 8th Philippine National Nutrition Survey
Angelique Bea Uy ; Cecilia Jimeno
Journal of the ASEAN Federation of Endocrine Societies 2021;36(1):12-24
Objectives:
This study looked into the prevalence of diabetes mellitus (DM) and risks for cardiovascular and metabolic diseases among young adults with diabetes (age 20-44 years old, YOD) and late-onset DM (≥45 years old, LOD) in Filipinos.
Methodology:
Weighted data from 546,580 adults with DM from the 8th Philippine National Nutrition and Health Survey (NNHeS) were utilized. Differences in sociodemographic, anthropometric, clinical profiles and metabolic risks were compared between YOD and LOD.
Results:
The aggregated prevalence of DM is 5.43% (95%CI, 5.10–5.79), YOD were 2.64% (95% CI, 2.32–3.00) and LOD 9.85% (95%CI, 9.18–10.56). Mean age of YOD was 37,6 years, LOD 59,9 years. The YOD were mostly males (56%), with higher BMI (26.24 kg/m2 vs 25 kg/m2, p=0.002), lower mean SBP (122.41±19.17 mmHg vs 135.45±22.47 mmHg, p<0.001), more daily smokers (23% vs 14%), and alcoholic beverage drinkers (39% vs 31%). Physical activity was similar between groups (44% vs 51%, p=0.078). However, average total caloric intake (1776.78±758.38 kcal vs 1596.88±639.16 kcal, p=0.023) and carbohydrate intake (306.13±142.16 grams vs 270.53±104.74 g, p=0.014) were higher in YOD. Dietary carbohydrate proportions were higher than recommended (69% vs 68%) for both groups. Young Filipinos had higher risk to develop diabetes when they are obese II (22% vs 12%), current drinker (56% vs 37%), and current smoker (28% vs 18%). Eighty percent of YOD and LOD had metabolic syndrome (MetS). With every unit increase in age and fat intake, the odds of having MetS were raised by 5.4% (95%CI 1%–10%, p=0.029) and 1.6% (95%CI 0.04%-3%, p=0.044), respectively.
Conclusion
Early-onset diabetes mellitus appears to be driven by obesity, MetS and social behaviors. Modifiable risk factors can be improved early to decrease hazards to develop cardiometabolic complications.
Metabolic Syndrome
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Cardiovascular Diseases
10.Androgenetic alopecia and its association with metabolic syndrome: A systematic review and meta-analysis.
Leah Antoinette M. CARO-CHANG ; Mia Katrina R. GERVASIO ; Claudine YAP-SILVA
Acta Medica Philippina 2019;53(2):122-131
OBJECTIVES: The study aimed to confirm the association between androgenetic alopecia (AGA) and Metabolic Syndrome (MetS). It also aimed to determine if early-onset AGA among males and AGA among females increases the risk of developing MetS, and if severity of AGA increases the odds of developing MetS.
METHODS: Observational studies from electronic databases were selected by the consensus of three independent review authors. The Newcastle-Ottawa Scale for assessing the quality of non-randomized studies in meta-analysis was used. Statistical analyses were accomplished using Review Manager software.
RESULTS: A total of 11 case-control studies, one prospective cohort study, and five cross-sectional studies were selected. In the meta-analysis of ten case-control studies and three cross-sectional studies (3840 participants), AGA was significantly correlated with MetS (OR 2.59, 95% CI 1.51 to 4.44; p<0.0005). Early-onset AGA among males (
CONCLUSION: Although the pathophysiology still remains under investigation, the present study points to an association between AGA and MetS. It can be used as a marker to identify patients who should be screened for MetS and managed accordingly.
Alopecia ; Metabolic Syndrome