OBJECTIVES: The prevalence of metabolic syndrome has recently increased. Payments from the Korea Labor Welfare Corporation for compensation for mortality in workers caused by cardiovascular and cerebrovascular diseases have also increased in Korea in recent years. The association of metabolic syndrome and cardiocere brovascular disease has been investigated by several researchers in recent studies. This study was conducted in an attempt to characterize the relationship between metabolic syndrome and Korean cardiocerebrovascular disease risk assessment, and to provide basic data to group health practices for the prevention of cardiocere brovascular disease. METHODS: Health examinations were previously conducted for 1526 male researchers at a private laboratory. The prevalence by age and the odds ratio of metabolic syndrome scores into the "cardiocerebrovascular risk group" (sum of low, intermediate, and high risk groups) of the Korean cardiocerebrovascular disease risk assessment were assessed, in an effort to elucidate the associations between metabolic syndrome and cardiocere brovascular disease risk assessment. RESULTS: The prevalence of metabolic syndrome and inclusion in the cardiocerebrovascular risk group was 11.7% and 22.1% respectively. The severity of metabolic syndrome and cardiocerebrovascular risk assessment showed that individuals in their 40's and 50's were at higher risk than those in their 30's (p<0.001). The age-adjusted odds ratio of metabolic syndrome to cardiocere brovascular risk group inclusion was 5.6. CONCLUSIONS: An active prevention program for cardiocerebrovascular disease needs to begin in the 40's, as the prevalence of metabolic syndrome and the risk group of cardiocerebrovascular risk assessment peak in the 40's age group. The odds ratio between metabolic syndrome and the cardiocerebrovascular risk group was high, which indicates that metabolic syndrome scores should be utilized as guidelines during the consultation and behavioral modification program for the workplace prevention of cardiocerebrovascular diseases in group health practices.
Age Distribution ; Cardiovascular Diseases/economics/*epidemiology ; Cerebrovascular Disorders/complications/*epidemiology ; Humans ; Korea/epidemiology ; Male ; Metabolic Syndrome X/complications/*epidemiology ; Prevalence

Antipsychotic Agents ; therapeutic use ; Cardiovascular Diseases ; epidemiology ; Female ; Humans ; Male ; Metabolic Syndrome ; epidemiology ; Schizophrenia ; drug therapy

Antipsychotic Agents ; therapeutic use ; Cardiovascular Diseases ; epidemiology ; Female ; Humans ; Male ; Metabolic Syndrome ; epidemiology ; Schizophrenia ; drug therapy

Adult ; Asymptomatic Diseases/epidemiology* ; Autoimmune Diseases/etiology* ; China/epidemiology* ; Female ; Humans ; Hypothyroidism/etiology* ; Male ; Metabolic Syndrome/epidemiology* ; Middle Aged ; Obesity/epidemiology* ; Risk Factors ; Thyroid Diseases/etiology* ; Young Adult

OBJECTIVEThe aim of the present study was to investigate the difference of intolerance to food between southern and northern middle-aged Chinese, and furthermore analyze its association with eating habits in both study population.

METHODSELISA was applied to determine the serum concentrations of specific IgG of 14 food anaphylactogen in 1568 healthy subjects from totally 9 districts in both southern and northern China. Life style questionnaire was also applied to investigate the daily intake of six categorizes of food associated with food intolerance.

RESULTS45.8% of all subjects were found to be intolerant to certain food. 62.3% of subjects from southern China and 40.4% of subjects from northern China were found to be intolerant to certain food, the difference between southern and northern Chinese was statistically significant. Top three foods intolerant by southern Chinese were crab, egg, and cold fish, while top three food intolerant by northern Chinese were egg, crab, and milk. The differences of intolerance to crab, cold fish, soy bean, rice, and tomato between southern and northern Chinese were statistically significant. Investigation on eating habits revealed that cereals and fish were the major food consumed by subjects in our study. There was no certain association between food intolerance and eating habits.

CONCLUSIONConsidering that there are differences between southern and northern Chinese, southern and northern Chinese should pay attention to their daily food in order to avoid food allergy.

Adult ; China ; epidemiology ; Feeding Behavior ; Female ; Food Hypersensitivity ; epidemiology ; Humans ; Male ; Metabolic Diseases ; epidemiology ; Middle Aged ; Surveys and Questionnaires

OBJECTIVETo study the relationship between prevalence of central obesity and clustering of cardiometabolic diseases among Chinese elder people over 60 years old.

METHODSA complex multistage stratified sampling survey on chronic diseases was conducted in 162 surveillance points, 31 provinces, China in 2010 by China CDC. The survey included face-to-face interview, physical measurement (body height, weight, waist circumference (WC) and blood pressure) and laboratory test (blood sugar, blood lipid and hemoglobin A1C), to collect the information about the prevalence of the risk factors as smoking, drinking, diet and physical activities and the prevalence of hypertension, diabetes and dyslipidemia. The survey selected 19 966 subjects who were over 60 years old. Central obesity was defined as WC ≥ 85 cm in males or ≥ 80 cm in females. The prevalence of central obesity among the elder people over 60 years old in different districts and populations was calculated; and the proportion of cardiometabolic diseases in groups of different WC was then analyzed.

RESULTSThe prevalence of central obesity among elderly population over 60 years old was 48.6% (95%CI:46.1%-51.2%), including 39.7% (95%CI:37.2%-42.2%) males and 57.3% (95%CI:54.5%-60.1%) females. The proportion of females was higher than that of males (χ(2) = 474.63, P < 0.01). The higher the education level, the higher the prevalence of central obesity among elderly men. There was no significant association among females. The higher the family income, the higher the prevalence of central obesity. The prevalence of central obesity was 59.2% in urban area, which was much higher than that in rural area (43.5%) (χ(2) = 50.06, P < 0.01). The proportion of hypertension, diabetes and clustering of cardiometabolic disease was separately 18.8% (95%CI:16.1%-21.5%) , 66.2% (95%CI:63.0%-69.4%) and 47.5% (95%CI:44.1%-50.8%) among elderly men with WC between 85 and 89 cm, and separately 24.0% (95%CI:21.2%-26.8%), 78.2% (95%CI:75.6%-80.8%) and 64.0% (95%CI:60.3%-67.6%) among elderly men with WC ≥ 90 cm; which were both higher than those among elderly men with WC < 85 cm (separately 13.4% (95%CI:11.5%-15.3%) , 58.3% ( 95%CI:55.5%-60.1%) and 30.8% (95%CI:28.7%-32.9%) ). The proportion of hypertension, diabetes and clustering of cardiometabolic disease was 20.1% (95%CI:17.4%-22.7%) , 68.6% (95%CI:65.5%-71.8%) and 48.1% (95%CI:44.6%-51.6%) among elderly women with WC between 80 and 84 cm, and separately 31.7% (95%CI:28.9%-34.4%) , 81.0% (95%CI:78.5%-83.5%) and 61.8% (95%CI:58.9%-64.8%) among elderly women with WC ≥ 85 cm; which were both higher than those among elderly women with WC < 80 cm (separately 12.8% (95%CI:10.8%-14.8%) , 60.1% (95%CI:57.1%-63.0%) and 30.4% (95%CI:27.3%-33.5%)).

CONCLUSIONNearly half of the Chinese elder people were central obese. The proportion of cardiometabolic diseases among central obesity was significantly higher than that among non-obese population. We should pay more concern about them in the future prevention and control of chronic diseases.

Aged ; Aged, 80 and over ; Body Mass Index ; Cardiovascular Diseases ; epidemiology ; China ; epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Male ; Metabolic Diseases ; epidemiology ; Middle Aged ; Obesity, Abdominal ; epidemiology ; Risk Factors

OBJECTIVETo screen the risk factors for osteopenia in youths.

METHODSNinety-nine subjects aged 15 to 43 years with primary osteopenia(-2.5

RESULTSBinary logistic regression identified 5 factors that showed significantly correlations to osteopenia, namely inactivity, prolonged use of computers, imbalanced diet, staying up late at night, and alcohol drinking (P=0.000 for all the factors with yield ratios all >80%). Joint clicking and skeletal pain were the most common symptoms, and most of the patients had complaints of fatigue, insomnia and gastric discomforts.

CONCLUSIONSInactivity, prolonged use of computers, imbalanced diet, staying up late at night, and alcohol drinking are the risk factors for osteopenia in youths. Most of the patients have a sub-health status, indicating the necessity of relevant interventions to prevent the occurrence of osteoporosis.

Adolescent ; Adult ; Bone Diseases, Metabolic ; epidemiology ; Female ; Humans ; Logistic Models ; Male ; Risk Factors ; Young Adult

OBJECTIVETo evaluate the trends of cardiovascular disease (CVD) risk factors between 1992 and 2002 (10 years) in a cohort of Beijing.

METHODSTwo separate surveys were carried out for a cohort (2740 subjects) in 1992 and 2002 according to methods of the WHO MONICA project. Systolic blood pressure (SBP) and diastolic blood pressure (DBP), body mass index (BMI), waist circumference (WC) and hip circumference (HC), serum total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), triglyceride (TG), glucose, prevalence of hypertension, rate of hypertension treatment and control were compared between 1992 and 2002.

RESULTS(1) Comparisons of the same age groups showed that CVD risk factors increased significantly during the 10 year period from 1992 to 2002. (2) Nineteen percent of the subjects with optimal BP in 1992 became hypertensive in 2002, and 45.3% of normal BP subjects in 1992 became hypertensive in 2002. (3) 43.8% of the subjects with normal blood lipid in 1992 became hyperlipidemia in 2002. (4) 37.0% of the subjects with normal BMI in 1992 became overweight in 2002, and 43.7% of subjects with normal WC in 1992 became high WC in 2002. (5) 14.6% of the subjects without metabolic syndrome in 1992 became with metabolic syndrome in 2002.

CONCLUSIONSThe levels of CVD risk factors in this cohort increased significantly in a 10 year period from 1992 to 2002. Most of the risk factors were related to unhealthy life styles. To modify unhealthy life style and control the increasing rate of major risk factors are the key to reduce CVD incidence.

Adult ; Body Mass Index ; Cardiovascular Diseases ; epidemiology ; China ; epidemiology ; Cohort Studies ; Humans ; Hypertension ; Male ; Metabolic Syndrome ; epidemiology ; Middle Aged ; Obesity ; epidemiology ; Risk Factors ; Waist-Hip Ratio

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease seen in patients with obesity, diabetes, and metabolic syndrome. Metabolic syndrome is an important predictor of the severe form of NAFLD, nonalcoholic steatohepatitis (NASH), and NASH patients with diabetes have an increased risk of liver cirrhosis and hepatocellular carcinoma. With the prevalence of obesity and diabetes around the world, NAFLD has become a global public health problem. NAFLD is not only one of the most important causes of liver-related disability and mortality, but also associated with the increasing incidence of diabetes and cardiovascular disease. The effective prevention and treatment of NAFLD is expected to reduce the burden of liver disease and cardiovascular disease. Therefore, this article overviews the advances in the diagnosis, prevention, and treatment of NAFLD.
Carcinoma, Hepatocellular ; epidemiology ; Cardiovascular Diseases ; epidemiology ; Diabetes Mellitus ; epidemiology ; Humans ; Liver Cirrhosis ; epidemiology ; Liver Neoplasms ; epidemiology ; Metabolic Syndrome ; epidemiology ; Non-alcoholic Fatty Liver Disease ; diagnosis ; epidemiology ; therapy ; Obesity ; epidemiology ; Prevalence

This study aimed to estimate nationwide prevalence of the metabolic syndrome and to identify its association with cardiovascular diseases. The data on a national representative sample of 6,147 adults from 1998 Korea National Health and Nutrition Survey were analyzed. The syndrome was determined according to two kinds of modified definition from ATP III, in which abdominal obesity was determined by waist circumference (WC) standard for Asians and waist-to-hip ratio (WHR). Based on the former, prevalence was 22.1% in men and 27.8% in women. However, based on the latter, prevalence was 28.6% and 27.8%, respectively. Although age-specific prevalence was higher in men than in women among the younger group, it became higher in women among the older group because of its steeper rise with age. In multiple logistic regression, the syndrome was found to be positively associated with cardiovascular diseases (adjusted odds ratios (ORs)1.97 by WC and 1.48 by WHR in men, and 1.54 and 1.31 in women). Moreover, its effect size exceeded that of total cholesterol (adjusted ORs 1.21 in men, and 1.08 in women) or LDL cholesterol (1.58 in men and 1.22 in women). It is obvious that the metabolic syndrome prevails in Korea, and its importance regarding cardiovascular diseases is considerable. Prevention strategies should be implemented immediately to avoid cardiovascular epidemic in the near future.
Adult ; Aged ; Body Constitution ; Cardiovascular Diseases/*epidemiology ; Female ; Human ; Korea/epidemiology ; Male ; Metabolic Syndrome X/*epidemiology ; Middle Aged ; Prevalence ; Risk Factors ; Support, Non-U.S. Gov't