OBJECTIVE To standardize the implementation methods for therapeutic drug monitoring （TDM） of meropenem and ensure the accuracy of TDM results， thereby facilitating the scientific development of individualized treatment regimens for meropenem. METHODS The expert consensus was launched by the Society of Therapeutic Drug Monitoring Pharmacists of Chinese Pharmacists Association. The compilation team comprised experts in clinical pharmacy， TDM technology， and pharmaceutical administration， and it was developed in accordance with the relevant recommendations from the methodology handbook of WHO and the guidelines for TDM guidelines development. Twelve clinical questions were selected through a three- round Delphi voting process conducted by the committee， followed by a comprehensive review of relevant original articles， systematic reviews， and guidelines through general databases. The GRADE approach was employed to evaluate the quality of evidence so as to formulate the consensus recommendations. The experts’ opinions were organized， revised and finally formed into a consensus. RESULTS Ultimately， the consensus presented 14 recommendations， mainly regarding all aspects of TDM processes including necessity， method， monitor timing， target PK/PD， medication adjustments based on PK/PD， and the quality control of TDM. CONCLUSIONS This consensus provides standardized methods and process suggestions for meropenem TDM in medical institutions in China， and is of great significance for meropenem individualized drug use， improving clinical efficacy， and ensuring drug safety.